Burki, Richard; Krasnov, A.; Bettge, Kathrin; Rexroad, C. E.; Afanasyev, S.; Antikainen, M.; Burkhardt-Holm, P.; Wahli, Thomas; Segner, Helmut (2012). Pathogenic infection confounds induction of the estrogenic biomarker vitellogenin in rainbow trout. Environmental toxicology and chemistry, 31(10), pp. 2318-23. SETAC Press 10.1002/etc.1966
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To examine the behavior of the estrogenic biomarker vitellogenin (VTG) under the combined impact of estrogens and pathogens, parasite-infected or noninfected rainbow trout were exposed to two doses of 17beta-estradiol (E2). Infected and E2-exposed fish showed significantly lower hepatic VTG mRNA levels than healthy fish. Transcriptome data suggest that this was due to energetic constraints. Reduced responsiveness of the VTG biomarker in parasitized fish might obscure detection of low-level field exposure.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute for Fish and Wildlife Health (FIWI) |
UniBE Contributor: |
Burki, Richard, Bettge, Kathrin, Wahli, Thomas, Segner, Helmut |
Subjects: |
600 Technology > 630 Agriculture |
ISSN: |
0730-7268 |
Publisher: |
SETAC Press |
Language: |
English |
Submitter: |
Andrea Stettler |
Date Deposited: |
27 Jan 2014 10:43 |
Last Modified: |
05 Dec 2022 14:27 |
Publisher DOI: |
10.1002/etc.1966 |
PubMed ID: |
22847860 |
BORIS DOI: |
10.7892/boris.40437 |
URI: |
https://boris.unibe.ch/id/eprint/40437 |
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