Autologous stem cell transplantation: leukapheresis product has anti-angiogenic effects in vivo correlating with neutrophil-derived VEGFR1

Luethy, Anita; Stenner, Frank; Lohri, Corinne; Muller, Christoph; Samaras, Panagiotis; Steiner, Rudolf; Van Den Broek, Maries; Mischo, Axel; Renner, Christoph; Knuth, Alexander; Ruegg, Curzio; Wenger, Roland H; Zweifel, Martin (2011). Autologous stem cell transplantation: leukapheresis product has anti-angiogenic effects in vivo correlating with neutrophil-derived VEGFR1. Anticancer research, 31(10), pp. 3115-24. Kapandriti: International Inst. of Anticancer Research

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High-dose chemotherapy (HDC) followed by autologous stem cell transplantation (ASCT) is used for the treatment of hemato-oncologic malignancies. In this study, we measured the effect of HDC/ASCT on plasma concentrations of antiangiogenic soluble vascular endothelial growth factor receptor 1 (sVEGFR1) and of leukapheresis products (LP) and patient serum on chick chorioallantoic (CAM) angiogenesis.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology

UniBE Contributor:

Zweifel, Martin

ISSN:

0250-7005

Publisher:

International Inst. of Anticancer Research

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:20

Last Modified:

05 Dec 2022 14:05

PubMed ID:

21965716

Web of Science ID:

000295667700001

URI:

https://boris.unibe.ch/id/eprint/6474 (FactScience: 211441)

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