Phosphate disorders: hyperphosphatemia or pseudohyperphosphatemia?

Aeberhard, Nicole; Schild, Christof; Rodondi, Nicolas; Roten, Christine; Tänzler, Kristina (2014). Phosphate disorders: hyperphosphatemia or pseudohyperphosphatemia? Praxis - schweizerische Rundschau für Medizin, 103(20), pp. 1203-1206. Huber 10.1024/1661-8157/a001792

Text fulltext.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (81kB)

We report the case of a 79 year old woman presenting with progressive confusion and drowsiness. Renal insufficiency with hyperkalemia as well as hypercalcemia and severe hyperphosphatemia were diagnosed. Renal insufficiency improved with treatment. However, hyperphosphatemia persisted without apparent explanation. We discuss possible causes of hyper- and pseudohyperphosphatemia. Specifically, phosphate analysis may be disturbed by the paraproteins in patients with multiple myeloma, resulting in pseudohyperphosphatemia. We review the standard laboratory phosphate measurement and the mechanisms of interference with paraproteins.

Interest & Impact

Downloads

2 since deposited on 16 Apr 2015
0 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item