Althaus, Christian L (2015). Of mice, macaques and men: scaling of virus dynamics and immune responses. Frontiers in Microbiology, 6, p. 355. Frontiers 10.3389/fmicb.2015.00355
|
Text
Althaus FrontMicrobiol 2015.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (87kB) | Preview |
In this Opinion piece, I argue that the dynamics of viruses and the cellular immune response depend on the body size of the host. I use allometric scaling theory to interpret observed quantitative differences in the infection dynamics of lymphocytic choriomeningitis virus (LCMV) in mice (Mus musculus), simian immunodeficiency virus (SIV) in rhesus macaques (Macaca mulatta) and human immunodeficiency virus (HIV) in humans.
Item Type: |
Journal Article (Further Contribution) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM) |
UniBE Contributor: |
Althaus, Christian |
Subjects: |
600 Technology > 610 Medicine & health 300 Social sciences, sociology & anthropology > 360 Social problems & social services |
ISSN: |
1664-302X |
Publisher: |
Frontiers |
Language: |
English |
Submitter: |
Doris Kopp Heim |
Date Deposited: |
19 May 2015 14:06 |
Last Modified: |
05 Dec 2022 14:46 |
Publisher DOI: |
10.3389/fmicb.2015.00355 |
PubMed ID: |
25954270 |
Uncontrolled Keywords: |
allometric scaling, viral dynamics, viral replication, immune escape, cellular immune response, mice, macaques, humans |
BORIS DOI: |
10.7892/boris.68430 |
URI: |
https://boris.unibe.ch/id/eprint/68430 |
Actions (login required)
 |
Edit item |