Fluorinated peptide nucleic acid

Hollenstein, Marcel; Gautschi, Daniel; Leumann, Christian (2003). Fluorinated peptide nucleic acid. Nucleosides, nucleotides & nucleic acids, 22(5-8), pp. 1191-1194. Taylor & Francis 10.1081/NCN-120022833

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The fluorinated olefinic peptide nucleic acid analogue (F-OPA) monomer containing the base thymine was synthesised in 13 steps. PNAs containing this unit were prepared and their pairing properties assessed by means of UV-melting experiments

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP)

UniBE Contributor:

Hollenstein, Marcel, Gautschi, Daniel, Leumann, Christian

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 540 Chemistry

ISSN:

1525-7770

Publisher:

Taylor & Francis

Language:

English

Submitter:

Christian Leumann

Date Deposited:

19 May 2015 09:25

Last Modified:

05 Dec 2022 14:46

Publisher DOI:

10.1081/NCN-120022833

PubMed ID:

14565377

Additional Information:

Notes: Department of Chemistry and Biochemistry, University of Bern, Bern, Switzerland hollenstein@iocunibechFAU - Hollenstein, Marcel

Uncontrolled Keywords:

ACID analogue base Base Sequence chemical synthesis chemistry Fluorine Indicators and Reagents Molecular Structure OLIGODEOXYRIBONUCLEOTIDES PAIRING PROPERTIES peptide Peptide Nucleic Acids PNA properties THYMINE

BORIS DOI:

10.7892/boris.68564

URI:

https://boris.unibe.ch/id/eprint/68564

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