A Minimally Invasive Technique for the Detection and Analysis of Pulmonary Fat Embolism: A Feasibility Study*

Filograna, Laura; Bolliger, Stephan; Kneubuehl, Beat; Jackowski, Christian; Hatch, Gary M; Thali, Michael J (2012). A Minimally Invasive Technique for the Detection and Analysis of Pulmonary Fat Embolism: A Feasibility Study*. Journal of forensic sciences, 57(5), pp. 1329-1335. Hoboken, N.J.: Wiley 10.1111/j.1556-4029.2012.02134.x

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We investigated the feasibility of postmortem percutaneous needle biopsy (PNB) for obtaining pulmonary samples adequate for the study of pulmonary fat embolism (PFE). Samples of both lungs were obtained from 26 cadavers via two different methods: (i) PNB and (ii) the double-edged knife technique, the gold standard at our institute. After water storage and Sudan III staining, six forensic pathologists independently examined all samples for the presence and severity of PFE. The results were compared and analyzed in each case regarding the vitality of the PFE and its relationship to the cause of death. The results showed that PFE was almost identically diagnosed and graded on the samples obtained via both methods. The discrepancies between the two techniques did not affect the diagnoses of vitality or cause of death related to PFE. This study demonstrates the feasibility of the PNB sampling method for the diagnosis and interpretation of PFE in the postmortem setting.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Legal Medicine > Forensic Medicine
04 Faculty of Medicine > Service Sector > Institute of Legal Medicine
04 Faculty of Medicine > Service Sector > Institute of Legal Medicine > Forensic Imaging

UniBE Contributor:

Filograna, Laura, Bolliger, Stephan, Kneubühl, Beat P., Hatch, Gary, Thali, Michael

ISSN:

0022-1198

Publisher:

Wiley

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:21

Last Modified:

05 Dec 2022 14:05

Publisher DOI:

10.1111/j.1556-4029.2012.02134.x

PubMed ID:

22509792

Web of Science ID:

000308391500028

URI:

https://boris.unibe.ch/id/eprint/6881 (FactScience: 211930)

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