Zahn, P K; Sabatowski, R; Schug, S A; Stamer, Ulrike; Pogatzki-Zahn, E M (2010). Paracetamol for perioperative analgesia. Old substance - new insights. Der Anaesthesist, 59(10), pp. 940-952. Springer 10.1007/s00101-010-1773-z
|
Text
s00101-010-1773-z.pdf - Published Version Available under License Publisher holds Copyright. Download (730kB) | Preview |
Since paracetamol was first synthesized in 1878 it has become one of the most popular and widely used drugs for the first-line treatment of fever and pain. The reasons for this popularity are a wide variety of formulations, an assumed positive safety record and the wide availability as an over-the-counter drug. However, recently several studies questioned the positive risk-benefit ratio of paracetamol for postoperative pain by observing several possible adverse effects and limitations. The aim of the present review is to give an update of the recent literature on the efficacy of paracetamol for postoperative pain and on the value of the clinical relevance of different adverse effects of paracetamol. Finally, based on the current findings the authors try to assess the role of paracetamol for the treatment of postoperative pain.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic and Policlinic for Anaesthesiology and Pain Therapy |
UniBE Contributor: |
Stamer, Ulrike |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1432-055X |
Publisher: |
Springer |
Language: |
German |
Submitter: |
Jeannie Wurz |
Date Deposited: |
17 Jul 2015 16:23 |
Last Modified: |
05 Dec 2022 14:48 |
Publisher DOI: |
10.1007/s00101-010-1773-z |
PubMed ID: |
20827451 |
BORIS DOI: |
10.48350/70339 |
URI: |
https://boris.unibe.ch/id/eprint/70339 |
Actions (login required)
 |
Edit item |