Outcomes of antiretroviral therapy in the Swiss HIV Cohort Study: latent class analysis

Keiser, Olivia; Spycher, Ben; Rauch, Andri; Calmy, Alexandra; Cavassini, Matthias; Glass, Tracy R; Nicca, Dunja; Ledergerber, Bruno; Egger, Matthias; Swiss HIV, Cohort Study (2012). Outcomes of antiretroviral therapy in the Swiss HIV Cohort Study: latent class analysis. AIDS and behavior, 16(2), pp. 245-55. New York, N.Y.: Springer 10.1007/s10461-011-9971-5

Preview	Text Keiser AIDSBehav 2012.pdf - Published Version Available under License Publisher holds Copyright. Download (291kB) | Preview
	Text Keiser AIDSBehav 2012_manuscript.doc - Accepted Version Available under License Publisher holds Copyright. Download (1MB)

An in-depth understanding of the different groups that make up the HIV-infected population should inform prevention and care. Using latent class analysis (LCA) we identified seven groups with similar socio-demographic and behavioral characteristics at enrolment in the Swiss HIV Cohort Study: older gay men, younger gay men, older heterosexual men, injection drug users, single migrants, migrant women in partnerships and heterosexual men and women. Outcomes of combination antiretroviral therapy (ART) were analyzed in 1,633 patients starting ART. Compared to older gay men, the probability of a virologic response to ART was reduced in single migrants, in older heterosexual men and in IDUs. Loss to follow-up was higher in single migrants and IDUs, and mortality was increased in older heterosexual men and IDUs. Socio-behavioral groups identified by LCA allow insights above what can be gleaned from traditional transmission groups, and may identify patients who could benefit from targeted interventions.

Interest & Impact

Downloads

393 since deposited on 04 Oct 2013
36 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item