Furrer, Julien; Süss-Fink, Georg (2016). Thiolato-bridged dinuclear arene ruthenium complexes and their potential as anticancer drugs. Coordination Chemistry Reviews, 309, pp. 36-50. Elsevier 10.1016/j.ccr.2015.10.007
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Water-soluble arene ruthenium complexes have been intensively studied as cytotoxic compounds for the last fifteen years, notably owing to the promising in vitro and in vivo evaluations of, respectively, RAPTA-C (η6-p-MeC6H4Pri)Ru(P-pta)Cl2 (pta = 1,3,5-triaza-7-phospha-tricyclo-[3.3.1.1]decane) from Dyson's laboratory, and the (η6-arene)Ru(en)Cl]+ (en = ethylenediamine, RAED) family of compounds from Sadler's laboratory. In this account we describe the discovery of thiolato-bridged dinuclear arene ruthenium complexes and highlight subsequent developments in the field, including their syntheses, structures, and the recent strategies for the design of thiolato-bridged dinuclear arene ruthenium bioconjugates.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Furrer, Julien |
Subjects: |
500 Science > 570 Life sciences; biology 500 Science > 540 Chemistry |
ISSN: |
0010-8545 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Julien Henri Lucien Furrer |
Date Deposited: |
14 Dec 2015 08:46 |
Last Modified: |
05 Dec 2022 14:50 |
Publisher DOI: |
10.1016/j.ccr.2015.10.007 |
BORIS DOI: |
10.7892/boris.73621 |
URI: |
https://boris.unibe.ch/id/eprint/73621 |
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