Incidence, predictive factors, and prognosis of chondrosarcoma in patients with Ollier disease and Maffucci syndrome: an international multicenter study of 161 patients

Verdegaal, Suzan H M; Bovée, Judith V M G; Pansuriya, Twinkal C; Grimer, Robert J; Ozger, Harzem; Jutte, Paul C; San Julian, Mikel; Biau, David J; van der Geest, Ingrid C M; Leithner, Andreas; Streitbürger, Arne; Klenke, Frank M; Gouin, Francois G; Campanacci, Domenico A; Marec-Berard, Perrine; Hogendoorn, Pancras C W; Brand, Ronald; Taminiau, Antonie H M (2011). Incidence, predictive factors, and prognosis of chondrosarcoma in patients with Ollier disease and Maffucci syndrome: an international multicenter study of 161 patients. Oncologist, 16(12), pp. 1771-9. Miamisburg, Ohio: AlphaMed Press 10.1634/theoncologist.2011-0200

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Enchondromatosis is characterized by the presence of multiple benign cartilage lesions in bone. While Ollier disease is typified by multiple enchondromas, in Maffucci syndrome these are associated with hemangiomas. Studies evaluating the predictive value of clinical symptoms for development of secondary chondrosarcoma and prognosis are lacking. This multi-institute study evaluates the clinical characteristics of patients, to get better insight on behavior and prognosis of these diseases.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Orthopaedic Surgery

UniBE Contributor:

Klenke, Frank M.

ISSN:

1083-7159

Publisher:

AlphaMed Press

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:22

Last Modified:

05 Dec 2022 14:06

Publisher DOI:

10.1634/theoncologist.2011-0200

PubMed ID:

22147000

Web of Science ID:

000298661000015

URI:

https://boris.unibe.ch/id/eprint/7420 (FactScience: 212680)

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