Gadaldi, Karolina; Erdemoğlu, Yeliz; Yawalkar, Nikhil (2015). Successful Treatment of Recalcitrant Prurigo with Alitretinoin. Dermatology, 231(4), pp. 330-333. Karger 10.1159/000435911
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Successful treatment of recalcitrant prurigo with alitretinoin- revised clean version.pdf - Accepted Version Available under License Publisher holds Copyright. Download (90kB) | Preview |
BACKGROUND
Chronic itch with secondary scratch lesions such as prurigo has a major impact on quality of life. Due to its relapsing nature and often unknown origin, its treatment is challenging.
OBJECTIVE
We sought to demonstrate that alitretinoin can be an efficacious and well-tolerated treatment in a patient suffering from chronic itch with concomitant prurigo and psoriatic lesions.
METHODS
Case report.
RESULTS
After 1 month of alitretinoin treatment (30 mg daily), itch as well as prurigo and psoriasis lesions decreased markedly. Three cycles of alitretinoin were administered, as each cessation of treatment led to relapse of the symptoms after 6-8 weeks. Tapering of the alitretinoin dose (30 mg every second day) after the third cycle allowed to maintain the effects for over 18 months.
CONCLUSION
Treatment of refractory prurigo with alitretinoin might be an efficacious alternative to standard therapies. In case of relapse, retreatment with alitretinoin reinduces a further long-lasting response.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Gadaldi, Karolina, Yawalkar, Nikhil |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1018-8665 |
Publisher: |
Karger |
Language: |
English |
Submitter: |
Andrea Studer-Gauch |
Date Deposited: |
16 Mar 2016 15:48 |
Last Modified: |
05 Dec 2022 14:52 |
Publisher DOI: |
10.1159/000435911 |
PubMed ID: |
26304762 |
BORIS DOI: |
10.7892/boris.76252 |
URI: |
https://boris.unibe.ch/id/eprint/76252 |
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