Wenning, Anna Silvia; Kirchner, Paul; Antwi, Kwadwo; Fani, Melpomeni; Wild, Damian; Christ, Emanuel; Gloor, Beat (2015). Preoperative Glucagon-like peptide-1 receptor imaging reduces surgical trauma and pancreatic tissue loss in insulinoma patients: a report of three cases. Patient safety in surgery, 9, p. 23. BioMed Central 10.1186/s13037-015-0064-7
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Preoperative Glucagon-like peptide-1 receptor imaging reduces surgical trauma and pancreatic tissue loss in insulinoma patients a report of three cases. .pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (2MB) | Preview |
BACKGROUND
Insulinomas are rare tumors, in the majority of cases best treated by surgical resection. Preoperative localization of insulinoma is challenging. The more precise the preoperative localization the less invasive and safer is the resection. The purpose of the study is to check the impact of a new technique to localize insulinoma on the surgical strategy.
FINDINGS
We present exact preoperative localization with Glucagon-like peptide-1 receptor (GLP-1R) imaging. This allows a more precise resection thereby reducing surgical access trauma, loss of healthy pancreatic tissue and increasing safety and quality of the surgical intervention.
CONCLUSION
With the help of precise preoperative localization of insulinoma with GLP-1R imaging the surgeon is able to minimize the amount of resected healthy pancreatic tissue. We hypothesize that GLP-1R imaging will become a preoperative diagnostic tool to be used for many patients scheduled for open or laparoscopic insulinoma resection.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Visceral Surgery 04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine |
UniBE Contributor: |
Wenning, Anna Silvia, Kirchner, Paul, Christ, Emanuel, Gloor, Beat |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1754-9493 |
Publisher: |
BioMed Central |
Language: |
English |
Submitter: |
Lilian Karin Smith-Wirth |
Date Deposited: |
30 Mar 2016 10:22 |
Last Modified: |
05 Dec 2022 14:52 |
Publisher DOI: |
10.1186/s13037-015-0064-7 |
PubMed ID: |
26034506 |
BORIS DOI: |
10.7892/boris.77506 |
URI: |
https://boris.unibe.ch/id/eprint/77506 |
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