Moleda, Lukas; Trebicka, Jonel; Dietrich, Peter; Gäbele, Erwin; Hellerbrand, Claus; Straub, Rainer H; Sauerbruch, Tilman; Schoelmerich, Juergen; Wiest, Reiner (2011). Amelioration of portal hypertension and the hyperdynamic circulatory syndrome in cirrhotic rats by neuropeptide Y via pronounced splanchnic vasoaction. Gut, 60(8), pp. 1122-32. London: BMJ Publishing Group 10.1136/gut.2010.226407
Full text not available from this repository.Splanchnic vasodilation triggers the development of the hyperdynamic circulatory syndrome in portal hypertension. Neuropeptide Y (NPY), a sympathetic co-transmitter of norepinephrine, improves contractility in mesenteric arteries of pre-hepatic portal hypertensive rats. Therefore, we investigated the effect of NPY on mesenteric arterial contractility in vitro and in vivo in cirrhotic ascitic rats, as well as the vasoactive pathways involved.
Item Type: |
Journal Article (Original Article) |
---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Gastroenterology |
UniBE Contributor: |
Wiest, Reiner |
ISSN: |
0017-5749 |
Publisher: |
BMJ Publishing Group |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:23 |
Last Modified: |
05 Dec 2022 14:06 |
Publisher DOI: |
10.1136/gut.2010.226407 |
PubMed ID: |
21317421 |
Web of Science ID: |
000292318200019 |
URI: |
https://boris.unibe.ch/id/eprint/7771 (FactScience: 213097) |