Management of floating thrombus in the aortic arch

Weiss, Salome; Bühlmann, Roman; von Allmen, Regula S; Makaloski, Vladimir; Carrel, Thierry; Schmidli, Jürg; Wyss, Thomas (2016). Management of floating thrombus in the aortic arch. Journal of thoracic and cardiovascular surgery, 152(3), pp. 810-817. Mosby 10.1016/j.jtcvs.2016.03.078

[img] Text
1-s2.0-S0022522316301015-main.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (870kB) | Request a copy
[img]
Preview
Text
Definitive Version - Management of floating thrombus in the aortic arch.pdf - Accepted Version
Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND).

Download (184kB) | Preview

OBJECTIVE

Floating aortic thrombus is an underrecognized source of systemic emboli and carries a life-threatening risk of stroke when located in the aortic arch. Optimal treatment is not established in available guidelines. We report our experience in managing floating thrombi in the aortic arch.

METHODS

Consecutive patients diagnosed with a floating aortic arch thrombus at a tertiary referral center between January 2008 and December 2014 were reviewed. Perioperative and midterm outcomes were assessed.

RESULTS

Ten patients (8 female) with a median age of 56 years (range, 47-82 years) were identified. Eight patients presented with a symptomatic embolic event, and 2 patients were asymptomatic. One patient presenting with stroke due to embolic occlusion of all supra-aortic vessels died 2 days after admission. Three patients (2 asymptomatic and 1 unfit for surgery) were treated conservatively by anticoagulation, leading to thrombus resolution in 2 patients. In the third patient, the thrombus persisted despite anticoagulation, resulting in recurrent embolic events. The remaining 6 patients underwent open thrombectomy of the aortic arch during deep hypothermic circulatory arrest. All patients treated by surgery had an uneventful postoperative course with no recurrent thrombus or embolic event during follow-up. Median follow-up of all patients was 17 months (range, 11-89 months).

CONCLUSIONS

Floating aortic arch thrombus is a dangerous source of systemic emboli. Surgical removal of the thrombus is easy to perform and followed by good clinical results. Conservative treatment with anticoagulation may be considered in asymptomatic, inoperable or high-risk patients.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Heart Surgery

UniBE Contributor:

Bühlmann, Roman, Makaloski, Vladimir, Carrel, Thierry, Schmidli, Jürg, Wyss, Thomas (B)

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0022-5223

Publisher:

Mosby

Language:

English

Submitter:

Daniela Huber

Date Deposited:

26 Jul 2016 11:44

Last Modified:

27 Feb 2024 14:28

Publisher DOI:

10.1016/j.jtcvs.2016.03.078

PubMed ID:

27160939

Uncontrolled Keywords:

aortic arch; embolism; thrombus

BORIS DOI:

10.7892/boris.84065

URI:

https://boris.unibe.ch/id/eprint/84065

Actions (login required)

Edit item Edit item
Provide Feedback