Impaired type I and type III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells

Vareille, Marjolaine; Alves, Marco P; Kopf, Brigitte S; Möller, Alexander; Geiser, Thomas; Johnston, Sebastian L; Edwards, Michael R; Regamey, Nicolas (2012). Impaired type I and type III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells. Thorax, 67(6), pp. 517-25. London: BMJ Publishing Group 10.1136/thoraxjnl-2011-200405

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Rhinoviruses are important triggers of pulmonary exacerbations and possible contributors to long-term respiratory morbidity in cystic fibrosis (CF), but mechanisms leading to rhinovirus-induced CF exacerbations are poorly understood. It is hypothesised that there is a deficient innate immune response of the airway epithelium towards rhinovirus infection in CF.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Pneumology

UniBE Contributor:

Kieninger, Elisabeth, Geiser, Thomas (A), Regamey, Nicolas

ISSN:

0040-6376

Publisher:

BMJ Publishing Group

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:24

Last Modified:

29 Mar 2023 23:32

Publisher DOI:

10.1136/thoraxjnl-2011-200405

PubMed ID:

22213737

Web of Science ID:

000304351300010

Additional Information:

Retracted (see new version)

URI:

https://boris.unibe.ch/id/eprint/8410 (FactScience: 213945)

Available Versions of this Item

  • Impaired type I and type III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells. (deposited 04 Oct 2013 14:24) [Currently Displayed]

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