Gilard, Martine; Schlüter, Michael; Snow, Thomas M; Dall'Ara, Gianni; Eltchaninoff, Helene; Moat, Neil; Goicolea, Javier; Ussia, Gian Paolo; Kala, Petr; Wenaweser, Peter Martin; Zembala, Marian; Nickenig, Georg; Price, Susanna; Alegria Barrero, Eduardo; Iung, Bernard; Zamorano, Pepe; Schuler, Gerhard; Corti, Roberto; Alfieri, Ottavio; Prendergast, Bernard; ... (2016). The 2011-2012 pilot European Society of Cardiology Sentinel Registry of Transcatheter Aortic Valve Implantation: 12-month clinical outcomes. EuroIntervention, 12(1), pp. 79-87. Europa Digital & Publishing 10.4244/EIJV12I1A15
Full text not available from this repository.AIMS
Our aim was to assess one-year outcomes of patients enrolled in the pilot European Sentinel Registry of Transcatheter Aortic Valve Implantation (TAVI).
METHODS AND RESULTS
One-year outcomes of 4,571 patients (81.4±7.2 years, 2,291 [50.1%] male) receiving TAVI with the SAPIEN XT (57.3%) or CoreValve prosthesis at 137 European centres were analysed using Kaplan-Meier and Cox proportional hazards regression techniques. At one year, 3,341 patients were alive, 821 had died, and 409 were lost to follow-up. Of 2,125 patients who underwent functional assessment, 1,916 (90%) were in New York Heart Association (NYHA) Class I/II at one year, with functional improvement from baseline noted in 1,682 patients (88%). One-year survival based on 4,564 patients was estimated at 79.1%. Independent baseline predictors of mortality were increasing age and logistic EuroSCORE, the presence of NYHA III/IV, chronic obstructive pulmonary disease, and atrial fibrillation. Female gender was associated with a 4% survival benefit at one year. Vascular access routes other than transfemoral were associated with poorer survival. Procedural failure and major periprocedural complications had an adverse impact on survival.
CONCLUSIONS
Contemporary European experience attests to the effectiveness of routine TAVI in unselected elderly patients.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology |
UniBE Contributor: |
Wenaweser, Peter Martin, Windecker, Stephan |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1774-024X |
Publisher: |
Europa Digital & Publishing |
Language: |
English |
Submitter: |
Judith Liniger |
Date Deposited: |
28 Dec 2016 16:37 |
Last Modified: |
05 Dec 2022 14:59 |
Publisher DOI: |
10.4244/EIJV12I1A15 |
PubMed ID: |
27173867 |
URI: |
https://boris.unibe.ch/id/eprint/89744 |
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