Spontaneous liver rupture after treatment with drug-eluting beads.

Ritter, C O; Wartenberg, Martin; Mottok, A; Steger, U; Goltz, J P; Hahn, D; Kickuth, R (2012). Spontaneous liver rupture after treatment with drug-eluting beads. Cardiovascular and interventional radiology, 35(1), pp. 198-202. Springer 10.1007/s00270-011-0145-7

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Spontaneous rupture of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. Pathophysiologic mechanisms are not yet fully known; it is suggested that rupture is preceded by reactive tissue edema and intratumerous bleeding, leading to a rapid expansion of tumour mass with risk of extrahepatic bleeding in the case of subcapsular localisation. This case report discusses a sudden, unexpected lethal complication in a 74 year-old male patient treated with TACE using DC Bead loaded with doxorubicin (DEBDOX) in a progressive multifocal HCC.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology > Clinical Pathology

UniBE Contributor:

Wartenberg, Martin

ISSN:

0174-1551

Publisher:

Springer

Language:

English

Submitter:

Doris Haefelin

Date Deposited:

18 Jan 2017 09:30

Last Modified:

05 Dec 2022 15:00

Publisher DOI:

10.1007/s00270-011-0145-7

PubMed ID:

21431968

BORIS DOI:

10.7892/boris.92178

URI:

https://boris.unibe.ch/id/eprint/92178

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