Oertel, Markus Florian; Schüpbach, Michael; Ghika, Joseph-André; Stieglitz, Lennart H; Fiechter, Michael; Kaelin, Alain; Raabe, Andreas; Pollo, Claudio (2017). Combined thalamic and subthalamic deep brain stimulation for tremor-dominant Parkinson's disease. Acta neurochirurgica, 159(2), pp. 265-269. Springer 10.1007/s00701-016-3044-5
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Deep brain stimulation (DBS) in the thalamic ventral intermediate (Vim) or the subthalamic nucleus (STN) reportedly improves medication-refractory Parkinson's disease (PD) tremor. However, little is known about the potential synergic effects of combined Vim and STN DBS. We describe a 79-year-old man with medication-refractory tremor-dominant PD. Bilateral Vim DBS electrode implantation produced insufficient improvement. Therefore, the patient underwent additional unilateral left-sided STN DBS. Whereas Vim or STN stimulation alone led to partial improvement, persisting tremor resolution occurred after simultaneous stimulation. The combination of both targets may have a synergic effect and is an alternative option in suitable cases.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery 04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology |
UniBE Contributor: |
Oertel, Markus Florian, Schüpbach, Michael, Kaelin, Alain, Raabe, Andreas, Pollo, Claudio |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0001-6268 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Nicole Söll |
Date Deposited: |
13 Jan 2017 17:00 |
Last Modified: |
05 Dec 2022 15:00 |
Publisher DOI: |
10.1007/s00701-016-3044-5 |
PubMed ID: |
27966027 |
Uncontrolled Keywords: |
Deep brain stimulation; Parkinson’s disease; Subthalamic nucleus; Thalamic ventral intermediate nucleus; Tremor |
BORIS DOI: |
10.7892/boris.92285 |
URI: |
https://boris.unibe.ch/id/eprint/92285 |
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