Obmann, Verena C.; Christe, Andreas; Ebner, Lukas; Szücs Farkas, Zsolt; Ott, Sebastian Robert; Yarram, Sai; Stranzinger, Enno (2017). Bone subtraction radiography in adult patients with cystic fibrosis. Acta radiologica, 58(8), pp. 929-936. Sage 10.1177/0284185116679456
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BACKGROUND
Bone subtraction radiography allows reading pulmonary changes of chest radiographs more accurately without superimposition of bones.
PURPOSE
To evaluate the value of bone subtraction chest radiography using dual energy (DE) bone subtracted lung images compared to conventional radiographs (CR) in adult patients with cystic fibrosis (CF).
MATERIAL AND METHODS
Forty-nine DE radiographs of 24 patients (16 men) with CF (mean age, 32 years; age range, 18-71 years) were included. Lung function tests were performed within 10 days of the radiographs. Two radiologists evaluated all CR, DE, and CR + DE radiographs using the modified Chrispin-Norman score (CNS) and a five-point score for the confidence. Findings were statistically evaluated by Friedman ANOVA and Wilcoxon matched-pairs test.
RESULTS
There was significant difference of CNS between CR and DE (P = 0.044) as well as CR and CR + DE (P < 0.001). CNS of CR images showed moderate correlation with FEV1% (R = 0.287, P = 0.046) while DE and CR + DE correlated poorly with FEV1% (R = 0.023, P = 0.874 and R = 0.04, P = 0.785). A higher confidence was achieved with bone-subtracted radiographs compared to radiographs alone (median, CR 3.3, DE 3.9, CR + DE 4.1, for both P < 0.001).
CONCLUSION
DE radiographs are reliable for the evaluation of adult patients with CF in acute exacerbation. For yearly surveillance, CR and DE radiographs may play a limited role. However, in clinical routine, DE radiographs are useful for adult CF patients and may depict more accurately inflammatory changes than CR.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
?? DCD5A442C25EE17DE0405C82790C4DE2 ?? 04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Pneumology |
UniBE Contributor: |
Obmann, Verena Carola, Christe, Andreas, Ebner, Lukas, Szücs Farkas, Zsolt, Ott, Sebastian Robert, Stranzinger, Enno |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0284-1851 |
Publisher: |
Sage |
Language: |
English |
Submitter: |
Rahel Holderegger |
Date Deposited: |
23 Jan 2017 15:33 |
Last Modified: |
05 Dec 2022 15:01 |
Publisher DOI: |
10.1177/0284185116679456 |
PubMed ID: |
27879399 |
Uncontrolled Keywords: |
Cystic fibrosis (CF); Dual-energy scanned projection radiography; adult; conventional radiography; respiratory function test; thorax |
BORIS DOI: |
10.7892/boris.93289 |
URI: |
https://boris.unibe.ch/id/eprint/93289 |
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