Tyrand, Rémi; Momjian, Shahan; Pollo, Claudio; Lysakowski, Christopher; Lascano, Agustina M; Vulliémoz, Serge; Schaller, Karl; Boëx, Colette (2016). Continuous Intraoperative Monitoring of Temporal Lobe Epilepsy Surgery. Stereotactic and functional neurosurgery, 94(6), pp. 404-412. Karger 10.1159/000452842
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BACKGROUND/AIMS
The monitoring of interictal epileptiform discharge rates (IEDRs) all along anterior temporal lobe resections (ATLRs) has never been reported. Here the effect of ATLR on continuous IEDR monitoring is described.
METHODS
IEDRs computed automatically during entire interventions were recorded in 34 patients (38.2%, 13/34 depth; 61.8%, 21/34 scalp electrodes only). Monitorings were invalidated when burst suppression occurred or if initial IEDRs were <5.
RESULTS
Monitoring was successful for 69.2% (9/13) of the patients with depth recordings and for 4.8% (1/21) of the patients with scalp recordings. Burst suppressions precluded it in 30.8% (4/13) of the depth and in 57.1% (12/21) of the scalp recordings. Initial IEDRs were <5 for 38.1% (8/21) of the scalp recordings. Significant IEDR decreases were observed in 8/10 patients with successful monitoring. These decreases started with resection of the superior temporal gyrus. IEDRs decreased further with amygdalohippocampectomy in 3/5 patients. At the 12-month follow-up, all patients with IEDR decreases remained seizure free; both patients without did not.
CONCLUSION
IEDR monitoring was possible with depth, but not with scalp electrodes. IEDR decreases started with resection of the superior temporal gyrus. A larger patient cohort is necessary to confirm the high predictive values of IEDR monitoring that could become a tool for surgery customization.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery |
UniBE Contributor: |
Pollo, Claudio |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1011-6125 |
Publisher: |
Karger |
Language: |
English |
Submitter: |
Nicole Söll |
Date Deposited: |
06 Apr 2017 10:28 |
Last Modified: |
05 Dec 2022 15:01 |
Publisher DOI: |
10.1159/000452842 |
PubMed ID: |
27997922 |
BORIS DOI: |
10.7892/boris.93657 |
URI: |
https://boris.unibe.ch/id/eprint/93657 |
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