Lapointe, Guillaume; Schenk, Kurt; Renaud, Philippe (2011). Concise Synthesis of Pyrrolidine and Indolizidine Alkaloids by a Highly Convergent Three-Component Reaction. Chemistry - a European journal, 17(11), pp. 3207-3212. Weinheim: Wiley-VCH 10.1002/chem.201003137
Full text not available from this repository. (Request a copy)The synthesis of pyrrolidine and indolizidine derivatives through radical carboazidation of alkenes with alpha-iodoketones, followed by reductive amination, is described. When properly substituted, further lactamization afforded pyrrolizidinones in good yield. This carboazidation/reductive amination sequence was efficiently applied to the total synthesis of three different simple alkaloids, including (+/-)-monomorine I.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Renaud, Philippe |
ISSN: |
0947-6539 |
Publisher: |
Wiley-VCH |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:26 |
Last Modified: |
05 Dec 2022 14:07 |
Publisher DOI: |
10.1002/chem.201003137 |
Web of Science ID: |
000288098800021 |
URI: |
https://boris.unibe.ch/id/eprint/9392 (FactScience: 215122) |
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