Dobrzynski, Maciej

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2024

Dobrzynski, Maciej; Grädel, Benjamin; Gagliardi, Paolo Armando; Pertz, Olivier (2024). Quantification of collective signalling in time-lapse microscopy images. Methods in microscopy, 1(1), pp. 19-30. de Gruyter 10.1515/mim-2024-0003

2023

Gagliardi, Paolo Armando; Grädel, Benjamin; Jacques, Marc-Antoine; Hinderling, Lucien; Ender, Pascal; Cohen, Andrew R; Kastberger, Gerald; Pertz, Olivier; Dobrzynski, Maciej (2023). Automatic detection of spatio-temporal signaling patterns in cell collectives. The Journal of cell biology, 222(10) Rockefeller Institute Press 10.1083/jcb.202207048

2022

Hell, Tanja; Dobrzyński, Maciej; Gröflin, Fabian; Reinhardt, Jakob K; Dürr, Lara; Pertz, Olivier; Hamburger, Matthias; Garo, Eliane (2022). Flavonoids from Ericameria nauseosa inhibiting PI3K/AKT pathway in human melanoma cells. Biomedicine & pharmacotherapy, 156(113754), p. 113754. Elsevier 10.1016/j.biopha.2022.113754

Dürr, Lara; Reinhardt, Jakob K; Dobrzyński, Maciej; Hell, Tanja; Smieško, Martin; Pertz, Olivier; Hamburger, Matthias; Garo, Eliane (2022). A Dimerosesquiterpene and Sesquiterpene Lactones from Artemisia argyi Inhibiting Oncogenic PI3K/AKT Signaling in Melanoma Cells. Journal of natural products, 85(11), pp. 2557-2569. American Chemical Society 10.1021/acs.jnatprod.2c00471

Ender, Pascal; Gagliardi, Paolo Armando; Dobrzyński, Maciej; Frismantiene, Agne; Dessauges, Coralie; Höhener, Thomas; Jacques, Marc-Antoine; Cohen, Andrew R; Pertz, Olivier (2022). Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis. Developmental cell, 57(18), 2153-2167.e6. Elsevier 10.1016/j.devcel.2022.08.008

Hell, Tanja; Rutz, Adriano; Dürr, Lara; Dobrzyński, Maciej; Reinhardt, Jakob K; Lehner, Timo; Keller, Morris; John, Anika; Gupta, Mahabir; Pertz, Olivier; Hamburger, Matthias; Wolfender, Jean-Luc; Garo, Eliane (2022). Combining Activity Profiling with Advanced Annotation to Accelerate the Discovery of Natural Products Targeting Oncogenic Signaling in Melanoma. Journal of natural products, 85(6), pp. 1540-1554. American Chemical Society 10.1021/acs.jnatprod.2c00146

Dessauges, Coralie; Mikelson, Jan; Dobrzyński, Maciej; Jacques, Marc-Antoine; Frismantiene, Agne; Gagliardi, Paolo Armando; Khammash, Mustafa; Pertz, Olivier (2022). Optogenetic actuator - ERK biosensor circuits identify MAPK network nodes that shape ERK dynamics. Molecular systems biology, 18(6), e10670. EMBO Press 10.15252/msb.202110670

Dürr, Lara; Hell, Tanja; Dobrzyński, Maciej; Mattei, Alberto; John, Anika; Augsburger, Nathanja; Bradanini, Gloria; Reinhardt, Jakob K; Rossberg, Florian; Drobnjakovic, Milos; Gupta, Mahabir P; Hamburger, Matthias; Pertz, Olivier; Garo, Eliane (2022). High-Content Screening Pipeline for Natural Products Targeting Oncogenic Signaling in Melanoma. Journal of natural products, 85(4), pp. 1006-1017. American Chemical Society 10.1021/acs.jnatprod.1c01154

Dobrzyński, Maciej; Jacques, Marc-Antoine; Pertz, Olivier (2022). Mining of Single-Cell Signaling Time-Series for Dynamic Phenotypes with Clustering. Methods in molecular biology, 2488, pp. 183-206. Springer 10.1007/978-1-0716-2277-3_13

2021

Jacques, Marc-Antoine; Dobrzyński, Maciej; Gagliardi, Paolo Armando; Sznitman, Raphael; Pertz, Olivier (2021). CODEX, a neural network approach to explore signaling dynamics landscapes. Molecular systems biology, 17(4), e10026. EMBO Press 10.15252/msb.202010026

2019

Blum, Yannick; Mikelson, Jan; Dobrzynski, Maciej; Ryu, Hyunryul; Jacques, Marc-Antoine; Jeon, Noo Li; Khammash, Mustafa; Pertz, Olivier (2019). Temporal perturbation of ERK dynamics reveals network architecture of FGF2/MAPK signaling. Molecular systems biology, 15(11), e8947. EMBO Press 10.15252/msb.20198947

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