Iliev, Asparouh Iliev

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2024

Hoffet, Michelle Salomé; Tomov, Nikola S.; Hupp, Sabrina; Mitchell, Timothy J; Iliev, Asparouh I. (2024). Glucose and Oxygen Levels Modulate the Pore-Forming Effects of Cholesterol-Dependent Cytolysin Pneumolysin from Streptococcus pneumoniae. Toxins, 16(6) MDPI 10.3390/toxins16060232

2023

Müller, Annelies; Lekhuleni, Cebile; Hupp, Sabrina; du Plessis, Mignon; Holivololona, Lalaina; Babiichuk, Eduard; Leib, Stephen L.; Grandgirard, Denis; Iliev, Asparouh I.; von Gottberg, Anne; Hathaway, Lucy J. (2023). Meningitis-associated pneumococcal serotype 8, ST 53, strain is hypervirulent in a rat model and has non-haemolytic pneumolysin which can be attenuated by liposomes. Frontiers in cellular and infection microbiology, 12 Frontiers 10.3389/fcimb.2022.1106063

2022

Hupp, Sabrina; Förtsch, Christina; Graber, Franziska; Mitchell, Timothy J; Iliev, Asparouh I (2022). Pneumolysin boosts the neuroinflammatory response to Streptococcus pneumoniae through enhanced endocytosis. Nature communications, 13(1), p. 5032. Nature Publishing Group 10.1038/s41467-022-32624-2

Baronti, Dario; Tomov, Nikola; Hupp, Sabrina; Mitchell, Timothy J; Iliev, Asparouh Iliev (2022). Dendritic spine loss deep in the neocortex and dendrite distortion with diffusion disturbances occur early in experimental pneumococcal meningitis. Frontiers in neuroscience, 16(912445), p. 912445. Frontiers Research Foundation 10.3389/fnins.2022.912445

2021

Hupp, Sabrina; Tomov, Nikola Stefanov; Bischoff, Carolin; Baronti, Dario; Iliev, Asparouh I. (2021). Easy to build cost-effective acute brain slice incubation system for parallel analysis of multiple treatment conditions. Journal of neuroscience methods, 366, p. 109405. Elsevier 10.1016/j.jneumeth.2021.109405

2020

Hupp, Sabrina; Iliev, Asparouh I. (2020). CSF-1 receptor inhibition as a highly effective tool for depletion of microglia in mixed glial cultures. Journal of neuroscience methods, 332, p. 108537. Elsevier 10.1016/j.jneumeth.2019.108537

2019

Hupp, Sabrina; Grandgirard, Denis; Mitchell, Timothy J.; Leib, Stephen; Hathaway, Lucy Jane; Iliev, Asparouh I. (2019). Pneumolysin and the bacterial capsule of Streptococcus pneumoniae cooperatively inhibit taxis and motility of microglia. Journal of neuroinflammation, 16(1), p. 105. BioMed Central 10.1186/s12974-019-1491-7

2018

Seele, Jana; Tauber, Simone C; Bunkowski, Stephanie; Baums, Christoph G; Valentin-Weigand, Peter; de Buhr, Nicole; Beineke, Andreas; Iliev, Asparouh Iliev; Brück, Wolfgang; Nau, Roland (2018). The inflammatory response and neuronal injury in Streptococcus suis meningitis. BMC infectious diseases, 18(1), p. 297. BioMed Central 10.1186/s12879-018-3206-6

2017

Hupp, Sabrina; Ribes, Sandra; Seele, Jana; Bischoff, Carolin; Förtsch, Christina; Maier, Elke; Benz, Roland; Mitchell, Timothy J; Nau, Roland; Iliev, Asparouh Iliev (2017). Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation. British journal of pharmacology, 174(23), pp. 4295-4307. Wiley-Blackwell 10.1111/bph.14027

Maurer, Jana; Hupp, Sabrina; Bischoff, Carolin; Foertsch, Christina; Mitchell, Timothy J; Chakraborty, Trinad; Iliev, Asparouh Iliev (2017). Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes. Toxins, 9(1) MDPI 10.3390/toxins9010034

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