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Martinez Flores, Danaë; Akhoundova, Dilara; Seipel, Katja; Legros, Myriam; Kronig, Marie-Noelle; Daskalakis, Michael; Bacher, Ulrike; Pabst, Thomas (2024). Gemtuzumab Ozogamicin and Stem Cell Mobilization for Autologous Stem Cell Transplantation in Favorable Risk Acute Myeloid Leukemia. Biomedicines, 12(7) MDPI 10.3390/biomedicines12071616
Seipel, Katja; Mandhair, Harpreet; Bacher, Ulrike; Pabst, Thomas (2024). FLT3 and IRAK4 Inhibitor Emavusertib in Combination with BH3-Mimetics in the Treatment of Acute Myeloid Leukemia. Current issues in molecular biology, 46(4), pp. 2946-2960. MDPI 10.3390/cimb46040184
Maru, Bruktawit; Messikommer, Alessandra; Huang, Linhui; Seipel, Katja; Kovecses, Olivia; Valk, Peter J M; Theocharides, Alexandre P A; Mercier, Francois E; Pabst, Thomas; McKeague, Maureen; Luedtke, Nathan W (2023). PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy. Cell reports. Medicine, 4(9), p. 101191. Elsevier 10.1016/j.xcrm.2023.101191
Messerli, Christian; Wiedemann, Gertrud; Porret, Naomi; Nagler, Michael; Seipel, Katja; Jeker, Barbara; Novak, Urban; Zeerleder, Sacha; Bacher, Ulrike; Pabst, Thomas (2023). Correlation of peripheral chimeric antigen receptor T-cell (CAR-T cell) mRNA expression levels with toxicities and outcome in patients with diffuse large B-cell lymphoma (DLBCL). Turkish journal of haematology, 40(3), pp. 187-196. Turkish Society of Haematology 10.4274/tjh.galenos.2023.2023.0136
Seipel, Katja; Kohler, Scarlett; Bacher, Ulrike; Pabst, Thomas (2023). HSP90 Inhibitor PU-H71 in Combination with BH3-Mimetics in the Treatment of Acute Myeloid Leukemia. Current issues in molecular biology, 45(9), pp. 7011-7026. MDPI 10.3390/cimb45090443
Seipel, Katja; Abbühl, Mariesol; Bacher, Vera; Nilius, Henning; Daskalakis, Michael; Pabst, Thomas (2023). Clinical Impact of Single Nucleotide Polymorphism in CD-19 on Treatment Outcome in FMC63-CAR-T Cell Therapy. Cancers, 15(11) MDPI AG 10.3390/cancers15113058
Gillich, Cédric; Akhoundova, Dilara; Hayoz, Michael; Aebi, Yolanda; Largiadèr, Carlo R; Seipel, Katja; Daskalakis, Michael; Bacher, Vera; Pabst, Thomas (2023). Efficacy and Safety of High-Dose Chemotherapy with Treosulfan and Melphalan in Multiple Myeloma. Cancers, 15(10) MDPI AG 10.3390/cancers15102699
Akhoundova Sanoyan, Dilara; Seipel, Katja; Bacher, Ulrike; Kronig, Marie-Noelle; Porret, Naomi; Wiedemann, Gertrud; Daskalakis, Michael; Pabst, Thomas (2023). Real-life experiences with CAR T-cell therapy with idecabtagene vicleucel (ide-cel) for triple-class exposed relapsed/refractory multiple myeloma patients. BMC cancer, 23(1), p. 345. BioMed Central 10.1186/s12885-023-10824-3
Heini, Alexander D; Beck, Philipp; Bacher, Ulrike; Seipel, Katja; Zander, Thilo; Daskalakis, Michael; Pabst, Thomas (2023). BeEAM Conditioning including High-Dose Bendamustine before Autologous Stem Cell Transplantation Is Safe and Effective in Patients with Waldenstrom's Macroglobulinemia. Journal of Clinical Medicine, 12(6) MDPI 10.3390/jcm12062378
Wittibschlager, Valerie; Bacher, Ulrike; Seipel, Katja; Porret, Naomi; Wiedemann, Gertrud; Haslebacher, Claudia; Hoffmann, Michèle; Daskalakis, Michael; Akhoundova, Dilara; Pabst, Thomas (2023). CAR T-Cell Persistence Correlates with Improved Outcome in Patients with B-Cell Lymphoma. International journal of molecular sciences, 24(6) MDPI 10.3390/ijms24065688
Bühler, Selina; Akhoundova, Dilara; Jeker, Barbara; Legros, Myriam; Seipel, Katja; Daskalakis, Michael; Bacher, Ulrike; Pabst, Thomas (2023). Stem Cell Mobilization with Ixazomib and G-CSF in Patients with Multiple Myeloma. Cancers, 15(2) MDPI AG 10.3390/cancers15020430
Seipel, Katja; Frey, Michèle; Nilius, Henning; Akhoundova, Dilara; Banz, Yara; Bacher, Ulrike; Pabst, Thomas (2023). Low-Frequency PPM1D Gene Mutations Affect Treatment Response to CD19-Targeted CAR T-Cell Therapy in Large B-Cell Lymphoma. Current oncology, 30(12), pp. 10463-10476. MDPI 10.3390/curroncol30120762
Rüegsegger, Laura; Schanz, Urs; Seipel, Katja; Pabst, Thomas; Schwegler, Jürg; Schmidt, Elisabeth; Schmidt, Adrian (2022). Emberger Syndrome – A Family History Over 3 Generations (In Press). Healthbook TIMES oncology hematology, 14(4), pp. 34-40. The Healthbook Company 10.36000/hbT.OH.2022.14.092
Seipel, Katja; Brügger, Yvo; Mandhair, Harpreet; Bacher, Ulrike; Pabst, Thomas (2022). Rationale for Combining the BCL2 Inhibitor Venetoclax with the PI3K Inhibitor Bimiralisib in the Treatment of IDH2- and FLT3-Mutated Acute Myeloid Leukemia. International journal of molecular sciences, 23(20) MDPI 10.3390/ijms232012587
Heini, Alexander D; Bacher, Ulrike; Porret, Naomi; Wiedemann, Gertrud; Legros, Myriam; Stalder Zeerleder, Denise; Seipel, Katja; Novak, Urban; Daskalakis, Michael; Pabst, Thomas (2022). Experiences with Glofitamab Administration following CAR T Therapy in Patients with Relapsed Mantle Cell Lymphoma. Cells, 11(17) MDPI 10.3390/cells11172747
Rentsch, Vera; Seipel, Katja; Banz, Yara; Wiedemann, Gertrud; Porret, Naomi; Bacher, Ulrike; Pabst, Thomas (2022). Glofitamab Treatment in Relapsed or Refractory DLBCL after CAR T-Cell Therapy. Cancers, 14(10) MDPI AG 10.3390/cancers14102516
Seipel, Katja; Porret, Naomi; Wiedemann, Gertrud; Jeker, Barbara; Bacher, Vera Ulrike; Pabst, Thomas (2022). sBCMA Plasma Level Dynamics and Anti-BCMA CAR-T-Cell Treatment in Relapsed Multiple Myeloma. Current issues in molecular biology, 44(4), pp. 1463-1471. MDPI 10.3390/cimb44040098
Seipel, Katja; Graber, Carolyn; Flückiger, Laura; Bacher, Vera; Pabst, Thomas (2021). Rationale for a Combination Therapy with the STAT5 Inhibitor AC-4-130 and the MCL1 Inhibitor S63845 in the Treatment of FLT3-Mutated or TET2-Mutated Acute Myeloid Leukemia. International journal of molecular sciences, 22(15) MDPI 10.3390/ijms22158092
Seipel, Katja; Kopp, Basil; Bacher, Ulrike; Pabst, Thomas (2021). BMI1-Inhibitor PTC596 in Combination with MCL1 Inhibitor S63845 or MEK Inhibitor Trametinib in the Treatment of Acute Leukemia. Cancers, 13(3) MDPI AG 10.3390/cancers13030581
Idle, Jeffrey R; Seipel, Katja; Bacher, Ulrike; Pabst, Thomas; Beyoğlu, Diren (2020). (2R,3S)-Dihydroxybutanoic Acid Synthesis as a Novel Metabolic Function of Mutant Isocitrate Dehydrogenase 1 and 2 in Acute Myeloid Leukemia. Cancers, 12(10) MDPI AG 10.3390/cancers12102842
Pabst, Thomas; Joncourt, Raphael; Shumilov, Evgenii; Heini, Alexander; Wiedemann, Gertrud; Legros, Myriam; Seipel, Katja; Schild, Christof; Jalowiec, Katarzyna; Mansouri, Behrouz; Fux, Michaela; Novak, Urban; Porret, Naomi; Zeerleder, Sacha; Bacher, Vera (2020). Analysis of IL-6 serum levels and CAR-T cell specific digital PCR in the context of cytokine release syndrome (CRS). Experimental hematology, 88, 7-14.e3. Elsevier 10.1016/j.exphem.2020.07.003
Seipel, Katja; Messerli, Christian; Wiedemann, Gertrud; Bacher, Ulrike; Pabst, Thomas (2020). MN1, FOXP1 and hsa-miR-181a-5p as prognostic markers in acute myeloid leukemia patients treated with intensive induction chemotherapy and autologous stem cell transplantation. Leukemia research, 89(106296), p. 106296. Elsevier 10.1016/j.leukres.2020.106296
Messikommer, Alessandra; Seipel, Katja; Byrne, Stephen; Valk, Peter J. M.; Pabst, Thomas; Luedtke, Nathan W. (2020). RNA Targeting in Acute Myeloid Leukemia. ACS pharmacology & translational science, 3(6), pp. 1225-1232. ACS Publications 10.1021/acsptsci.0c00120
Seipel, Katja; Schmitter, Karin; Bacher, Ulrike; Pabst Müller, Thomas Niklaus (2019). Rationale for a Combination Therapy Consisting of MCL1- and MEK-Inhibitors in Acute Myeloid Leukemia. Cancers, 11(11) MDPI AG 10.3390/cancers11111779
Hitz, F; Kraus, M; Pabst, Thomas; Hess, D; Besse, L; Silzle, T; Novak, Urban; Seipel, Katja; Rondeau, S; Stüdeli, S; Vilei, S Berardi; Samaras, P; Mey, U; Driessen, C (2019). Nelfinavir and lenalidomide/dexamethasone in patients with lenalidomide-refractory multiple myeloma. A phase I/II Trial (SAKK 39/10). Blood cancer journal, 9(9), p. 70. Springer Nature 10.1038/s41408-019-0228-2
Mueller, Beatrice U; Seipel, Katja; Pabst Müller, Thomas Niklaus (2018). Myelodysplastic syndromes and acute myeloid leukemias in the elderly. European journal of internal medicine, 58, pp. 28-32. Elsevier 10.1016/j.ejim.2018.05.026
Seipel, Katja; Marques, Miguel A T; Sidler, Corinne; Mueller, Beatrice U; Pabst Müller, Thomas Niklaus (2018). MDM2- and FLT3-inhibitors in the treatment of -ITD acute myeloid leukemia, specificity and efficacy of NVP-HDM201 and midostaurin. Haematologica - the hematology journal, 103(11), pp. 1862-1872. Ferrata-Storti Foundation 10.3324/haematol.2018.191650
Alva, Laura C; Bacher, Vera Ulrike; Seipel, Katja; Mansouri Taleghani, Behrouz; Mueller, Beatrice U; Novak, Urban; Pabst, Thomas (2018). Iron overload is correlated with impaired autologous stem cell mobilization and survival in acute myeloid leukemia. Transfusion, 58(10), pp. 2365-2373. Wiley-Blackwell 10.1111/trf.14895
Seipel, Katja; Marques, Miguel A T; Sidler, Corinne; Mueller, Beatrice U; Pabst Müller, Thomas Niklaus (2018). The Cellular p53 Inhibitor MDM2 and the Growth Factor Receptor FLT3 as Biomarkers for Treatment Responses to the MDM2-Inhibitor Idasanutlin and the MEK1 Inhibitor Cobimetinib in Acute Myeloid Leukemia. Cancers, 10(6) MDPI AG 10.3390/cancers10060170
Berger, Martin Dave; Heini, Alexander D; Seipel, Katja; Mueller, Beatrice; Angelillo-Scherrer, Anne; Pabst, Thomas (2017). Increased fibrinogen levels at diagnosis are associated with adverse outcome in patients with acute myeloid leukemia. Hematological oncology, 35(4), pp. 789-796. Wiley 10.1002/hon.2307
Oberson, JS; Novak, Urban; Mansouri Taleghani, Behrouz; Baerlocher, Gabriela M.; Seipel, Katja; Mueller, BU; Leibundgut, Kurt; Zimmerli, Stefan; Pabst, Thomas (2017). Revisiting G-CSF Support for Hematologic Recovery after Autologous Transplantation in AML Patients. Annals of Hematology & Oncology, 4(5), p. 1148. Austin Publishing Group 10.26420/annhematoloncol.2017.1148
Heini, Alexander D; Berger, Martin Dave; Seipel, Katja; Mansouri Taleghani, Behrouz; Baerlocher, Gabriela M.; Leibundgut, Kurt; Banz Wälti, Yara; Novak, Urban; Pabst, Thomas (2017). Consolidation with autologous stem cell transplantation in first remission is safe and effective in AML patients above 65 years. Leukemia research, 53, pp. 28-34. Elsevier 10.1016/j.leukres.2016.12.001
Stettler, Jasmin; Novak, Urban; Baerlocher, Gabriela M.; Seipel, Katja; Mansouri Taleghani, Behrouz; Pabst, Thomas (2017). Autologous stem cell transplantation in elderly patients with multiple myeloma: evaluation of its safety and efficacy. Leukemia & lymphoma, 58(5), pp. 1076-1083. Informa Healthcare 10.1080/10428194.2016.1233542
Fridle, Chantal; Medinger, Michael; Wilk, Matthias C; Seipel, Katja; Passweg, Jakob; Manz, Markus G; Pabst, Thomas (2017). Cladribine, cytarabine and idarubicin (CLA-Ida) salvage chemotherapy in relapsed acute myeloid leukemia (AML). Leukemia & lymphoma, 58(5), pp. 1068-1075. Informa Healthcare 10.1080/10428194.2016.1235274
Seipel, Katja; Marques, Miguel Teixera; Bozzini, Marie-Ange; Meinken, Christina; Mueller, Beatrice U; Pabst, Thomas (2016). Inactivation of the p53-KLF4-CEBPA Axis in Acute Myeloid Leukemia. Clinical cancer research, 22(3), pp. 746-756. American Association for Cancer Research 10.1158/1078-0432.CCR-15-1054
Pathak, Anand; Seipel, Katja; Pemov, Alexander; Dewan, Ramita; Brown, Christina; Ravichandran, Sarangan; Luke, Brian T; Malasky, Michael; Suman, Shalabh; Yeager, Meredith; Cancer GenomicsResearch Laboratory, Nci Dceg; Cancer Sequencing Working Group, Nci Dceg; Parry, Dilys M; Gatti, Richard A; Caporaso, Neil E; Mulvihill, John; Goldin, Lynn R; Pabst, Thomas; McMaster, Mary L and Stewart, Douglas R (2016). Whole-exome sequencing reveals a C-terminal germline variant in CEBPA-associated acute myeloid leukemia: 45-year follow-up of a large family. Haematologica - the hematology journal, 101(7), pp. 846-852. Ferrata-Storti Foundation 10.3324/haematol.2015.130799
Mueller, Beatrice U; Keller, Sandra; Seipel, Katja; Mansouri Taleghani, Behrouz; Rauch, Daniel; Betticher, Daniel; Egger, Thomas; Pabst, Thomas (2015). Stem cell mobilization chemotherapy with gemcitabine is effective and safe in myeloma patients with bortezomib-induced neurotoxicity. Leukemia & lymphoma, 57(5), pp. 1122-1129. Informa Healthcare 10.3109/10428194.2015.1079315
Schardt, Julian; Keller, Manuela; Seipel, Katja; Pabst, Thomas (2015). Functional interplay of SP family members and nuclear factor Y is essential for transcriptional activation of the human Calreticulin gene. Biochimica et biophysica acta - gene regulatory mechanisms, 1849(9), pp. 1188-1197. Elsevier 10.1016/j.bbagrm.2015.07.003
Keller, Sandra; Seipel, Katja; Novak, Urban; Mueller, Beatrice U; Mansouri Taleghani, Behrouz; Leibundgut, Kurt; Pabst, Thomas (2015). Neurotoxicity of stem cell mobilization chemotherapy with vinorelbine in myeloma patients after bortezomib treatment. Leukemia research, 39(7), pp. 786-792. Elsevier 10.1016/j.leukres.2015.03.015
Berger, Martin Dave; Branger, Giacomo; Leibundgut, Kurt; Baerlocher, Gabriela M; Seipel, Katja; Mueller, Beatrice U; Gregor, Michael; Ruefer, Axel; Pabst, Thomas (2015). CD34+ selected versus unselected autologous stem cell transplantation in patients with advanced-stage mantle cell and diffuse large B-cell lymphoma. Leukemia research, 39(6), pp. 561-567. Elsevier 10.1016/j.leukres.2015.03.004
Wetzel, Dana; Müller, Beatrice Ursula; Mansouri Taleghani, Behrouz; Baerlocher, Gabriela M.; Seipel, Katja; Leibundgut, Kurt; Pabst, Thomas (2015). Delayed Haematological recovery after autologous stem cell transplantation is associated with favourable outcome in acute myeloid leukaemia. British journal of haematology, 168(2), pp. 268-273. Wiley-Blackwell 10.1111/bjh.13118
Messikomer, A; Bruktawit, M; Seipel, Katja; Valk, P; Theocharides, A; Pabst, Thomas; Mckeague, M; Luedtke, N (25 May 2021). Cancer Prognosis According to Parthanatos Features (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2021.05.24.445484
