 | Up a level |
Ferreira de Sousa, Maria Cristina; Imhof, Dennis; Hänggeli, Kai Pascal Alexander; Choi, Ryan; Hulverson, Matthew A; Arnold, Samuel L M; Van Voorhis, Wesley C; Fan, Erkang; Roberto, Sánchez-Sánchez; Ortega-Mora, Luis M; Hemphill, Andrew (2024). Efficacy of the bumped kinase inhibitor BKI-1708 against the cyst-forming apicomplexan parasites Toxoplasma gondii and Neospora caninum in vitro and in experimentally infected mice. International journal for parasitology. Drugs and drug resistance, 25, p. 100553. Elsevier 10.1016/j.ijpddr.2024.100553
Anghel, Nicoleta; Imhof, Dennis; Winzer, Pablo; Balmer, Vreni; Ramseier, Jessica; Haenggeli, Kai; Choi, Ryan; Hulverson, Matthew A; Whitman, Grant R; Arnold, Samuel L M; Ojo, Kayode K; Van Voorhis, Wesley C; Doggett, J Stone; Ortega-Mora, Luis M; Hemphill, Andrew (2021). Endochin-like quinolones (ELQs) and bumped kinase inhibitors (BKIs): Synergistic and additive effects of combined treatments against Neospora caninum infection in vitro and in vivo. International journal for parasitology. Drugs and drug resistance, 17, pp. 92-106. Elsevier 10.1016/j.ijpddr.2021.08.007
Imhof, Dennis; Anghel, Nicoleta; Winzer, Pablo; Balmer, Vreni; Ramseier, Jessica; Hänggeli, Kai; Choi, Ryan; Hulverson, Matthew A; Whitman, Grant R; Arnold, Samuel L M; Ojo, Kayode K; Van Voorhis, Wesley C; Doggett, J Stone; Ortega-Mora, Luis M; Hemphill, Andrew (2021). In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma gondii oocysts. International journal for parasitology. Drugs and drug resistance, 16, pp. 90-101. Elsevier 10.1016/j.ijpddr.2021.05.001
Van Voorhis, Wesley C; Hulverson, Matthew A; Choi, Ryan; Huang, Wenlin; Arnold, Samuel L M; Schaefer, Deborah A; Betzer, Dana P; Vidadala, Rama S R; Lee, Sangun; Whitman, Grant R; Barrett, Lynn K; Maly, Dustin J; Riggs, Michael W; Fan, Erkang; Kennedy, Thomas J; Tzipori, Saul; Doggett, J Stone; Winzer, Pablo; Anghel, Nicoleta; Imhof, Dennis; ... (2021). One health therapeutics: Target-Based drug development for cryptosporidiosis and other apicomplexa diseases. Veterinary parasitology, 289, p. 109336. Elsevier 10.1016/j.vetpar.2020.109336
Choi, Ryan; Hulverson, Matthew A; Huang, Wenlin; Vidadala, Rama S R; Whitman, Grant R; Barrett, Lynn K; Schaefer, Deborah A; Betzer, Dana P; Riggs, Michael W; Doggett, J Stone; Hemphill, Andrew; Ortega-Mora, Luis Miguel; McCloskey, Molly C; Arnold, Samuel L M; Hackman, Robert C; Marsh, Kennan C; Lynch, James J; Freiberg, Gail M; Leroy, Bruce E; Kempf, Dale J; ... (2020). Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned. International journal for parasitology, 50(5), pp. 413-422. Elsevier 10.1016/j.ijpara.2020.01.006
Hulverson, Matthew A; Choi, Ryan; Arnold, Samuel L M; Schaefer, Deborah A; Hemphill, Andrew; McCloskey, Molly C; Betzer, Dana P; Müller, Joachim; Vidadala, Rama S R; Whitman, Grant R; Rivas, Kasey L; Barrett, Lynn K; Hackman, Robert C; Love, Melissa S; McNamara, Case W; Shaughnessy, Thomas K; Kondratiuk, Alison; Kurnick, Matthew; Banfor, Patricia N; Lynch, James J; ... (2017). Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis. International journal for parasitology, 47(12), pp. 753-763. Elsevier 10.1016/j.ijpara.2017.08.006
