Blume, Tanja

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Journal Article

Blume, Tanja; Deussing, Maximilian; Biechele, Gloria; Peters, Finn; Zott, Benedikt; Schmidt, Claudio; Franzmeier, Nicolai; Wind, Karin; Eckenweber, Florian; Sacher, Christian; Shi, Yuan; Ochs, Katharina; Kleinberger, Gernot; Xiang, Xianyuan; Focke, Carola; Lindner, Simon; Gildehaus, Franz-Josef; Beyer, Leonie; von Ungern-Sternberg, Barbara; Bartenstein, Peter; ... (2022). Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition. Frontiers in aging neuroscience, 14, p. 854031. Frontiers Research Foundation 10.3389/fnagi.2022.854031

Biechele, Gloria; Sebastian Monasor, Laura; Wind, Karin; Blume, Tanja; Parhizkar, Samira; Arzberger, Thomas; Sacher, Christian; Beyer, Leonie; Eckenweber, Florian; Gildehaus, Franz-Josef; von Ungern-Sternberg, Barbara; Willem, Michael; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen; Lichtenthaler, Stefan; Haass, Christian; Tahirovic, Sabina and Brendel, Matthias (2022). Glitter in the Darkness? Non-fibrillar β-amyloid Plaque Components Significantly Impact the β-amyloid PET Signal in Mouse Models of Alzheimer's Disease. Journal of nuclear medicine, 63(1), pp. 117-124. Society of Nuclear Medicine 10.2967/jnumed.120.261858

Xiang, Xianyuan; Wind, Karin; Wiedemann, Thomas; Blume, Tanja; Shi, Yuan; Briel, Nils; Beyer, Leonie; Biechele, Gloria; Eckenweber, Florian; Zatcepin, Artem; Lammich, Sven; Ribicic, Sara; Tahirovic, Sabina; Willem, Michael; Deussing, Maximilian; Palleis, Carla; Rauchmann, Boris-Stephan; Gildehaus, Franz-Josef; Lindner, Simon; Spitz, Charlotte; ... (2021). Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases. Science translational medicine, 13(615), eabe5640. American Association for the Advancement of Science 10.1126/scitranslmed.abe5640

Biechele, Gloria; Blume, Tanja; Deussing, Maximilian; Zott, Benedikt; Shi, Yuan; Xiang, Xianyuan; Franzmeier, Nicolai; Kleinberger, Gernot; Peters, Finn; Ochs, Katharina; Focke, Carola; Sacher, Christian; Wind, Karin; Schmidt, Claudio; Lindner, Simon; Gildehaus, Franz-Josef; Eckenweber, Florian; Beyer, Leonie; von Ungern-Sternberg, Barbara; Bartenstein, Peter; ... (2021). Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation. Theranostics, 11(18), pp. 8964-8976. Ivyspring International 10.7150/thno.64022

Biechele, Gloria; Wind, Karin; Blume, Tanja; Sacher, Christian; Beyer, Leonie; Eckenweber, Florian; Franzmeier, Nicolai; Ewers, Michael; Zott, Benedikt; Lindner, Simon; Gildehaus, Franz-Josef; von Ungern-Sternberg, Barbara; Tahirovic, Sabina; Willem, Michael; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen; Brendel, Matthias (2021). Microglial Activation in the Right Amygdala-Entorhinal-Hippocampal Complex is Associated with Preserved Spatial Learning in AppNL-G-F mice. NeuroImage, 230, p. 117707. Elsevier 10.1016/j.neuroimage.2020.117707

Palleis, Carla; Sauerbeck, Julia; Beyer, Leonie; Harris, Stefanie; Schmitt, Julia; Morenas-Rodriguez, Estrella; Finze, Anika; Nitschmann, Alexander; Ruch-Rubinstein, Francois; Eckenweber, Florian; Biechele, Gloria; Blume, Tanja; Shi, Yuan; Weidinger, Endy; Prix, Catharina; Bötzel, Kai; Danek, Adrian; Rauchmann, Boris-Stephan; Stöcklein, Sophia; Lindner, Simon; ... (2021). In Vivo Assessment of Neuroinflammation in 4-Repeat Tauopathies. Movement disorders, 36(4), pp. 883-894. Wiley-Blackwell 10.1002/mds.28395

Biechele, Gloria; Franzmeier, Nicolai; Blume, Tanja; Ewers, Michael; Luque, Jose Medina; Eckenweber, Florian; Sacher, Christian; Beyer, Leonie; Ruch-Rubinstein, Francois; Lindner, Simon; Gildehaus, Franz-Josef; von Ungern-Sternberg, Barbara; Cumming, Paul; Bartenstein, Peter; Rominger, Axel; Höglinger, Günter U; Herms, Jochen; Brendel, Matthias (2020). Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases. Journal of neuroinflammation, 17(1), p. 374. BioMed Central 10.1186/s12974-020-02046-2

Sacher, Christian; Blume, Tanja; Beyer, Leonie; Biechele, Gloria; Sauerbeck, Julia; Eckenweber, Florian; Deussing, Maximilian; Focke, Carola; Parhizkar, Samira; Lindner, Simon; Gildehaus, Franz-Josef; von Ungern-Sternberg, Barbara; Baumann, Karlheinz; Tahirovic, Sabina; Kleinberger, Gernot; Willem, Michael; Haass, Christian; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; ... (2020). Asymmetry of Fibrillar Plaque Burden in Amyloid Mouse Models. Journal of nuclear medicine, 61(12), pp. 1825-1831. Society of Nuclear Medicine 10.2967/jnumed.120.242750

Eckenweber, Florian; Medina-Luque, Jose; Blume, Tanja; Sacher, Christian; Biechele, Gloria; Wind, Karin; Deussing, Maximilian; Briel, Nils; Lindner, Simon; Boening, Guido; von Ungern-Sternberg, Barbara; Unterrainer, Marcus; Albert, Nathalie L; Zwergal, Andreas; Levin, Johannes; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Höglinger, Günter U; Herms, Jochen; ... (2020). Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning. Journal of neuroinflammation, 17(1), p. 208. BioMed Central 10.1186/s12974-020-01883-5

Sacher, Christian; Blume, Tanja; Beyer, Leonie; Peters, Finn; Eckenweber, Florian; Sgobio, Carmelo; Deussing, Maximilian; Albert, Nathalie L; Unterrainer, Marcus; Lindner, Simon; Gildehaus, Franz-Josef; von Ungern-Sternberg, Barbara; Brzak, Irena; Neumann, Ulf; Saito, Takashi; Saido, Takaomi C; Bartenstein, Peter; Rominger, Axel; Herms, Jochen and Brendel, Matthias (2019). Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second-Generation Amyloid-β Mouse Model. The journal of nuclear medicine, 60(12), pp. 1787-1793. Society of Nuclear Medicine and Molecular Imaging 10.2967/jnumed.119.227322

Focke, Carola; Blume, Tanja; Zott, Benedikt; Shi, Yuan; Deussing, Maximilian; Peters, Finn; Schmidt, Claudio; Kleinberger, Gernot; Lindner, Simon; Gildehaus, Franz-Josef; Beyer, Leonie; von Ungern-Sternberg, Barbara; Bartenstein, Peter; Ozmen, Laurence; Baumann, Karlheinz; Dorostkar, Mario M; Haass, Christian; Adelsberger, Helmuth; Herms, Jochen; Rominger, Axel Oliver; ... (2019). Early and longitudinal microglial activation but not amyloid accumulation predict cognitive outcome in PS2APP mice. Journal of nuclear medicine, 60(4), pp. 548-554. Society of Nuclear Medicine 10.2967/jnumed.118.217703

Brendel, Matthias; Deussing, Maximilian; Blume, Tanja; Kaiser, Lena; Probst, Federico; Overhoff, Felix; Peters, Finn; von Ungern-Sternberg, Barbara; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Zwergal, Andreas; Levin, Johannes; Bartenstein, Peter; Yakushev, Igor; Cumming, Paul; Boening, Guido; Ziegler, Sibylle; Herms, Jochen; Giese, Armin; ... (2019). Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau. Alzheimer's research & therapy, 11(1), p. 67. BioMed Central 10.1186/s13195-019-0522-z

Blume, Tanja; Focke, Carola; Peters, Finn; Deussing, Maximilian; Albert, Nathalie L.; Lindner, Simon; Gildehaus, Franz-Josef; von Ungern-Sternberg, Barbara; Ozmen, Laurence; Baumann, Karlheinz; Bartenstein, Peter; Rominger, Axel; Herms, Jochen; Brendel, Matthias (2018). Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study. Journal of neuroinflammation, 15(1), p. 307. BioMed Central 10.1186/s12974-018-1347-6

Brendel, Matthias; Jaworska, Anna; Overhoff, Felix; Blume, Tanja; Probst, Federico; Gildehaus, Franz-Josef; Bartenstein, Peter; Haass, Christian; Bohrmann, Bernd; Herms, Jochen; Willem, Michael; Rominger, Axel (2018). Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional Aβ deposition rate and plaque burden at treatment initiation. Theranostics, 8(18), pp. 4957-4968. Ivyspring International 10.7150/thno.27868

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