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Anliker-Ort, Marion; Rodieux, Frédérique; Ziesenitz, Victoria C; Atkinson, Andrew; Bielicki, Julia A; Erb, Thomas O; Gürtler, Nicolas; Holland-Cunz, Stefan; Duthaler, Urs; Rudin, Deborah; Haschke, Manuel; van den Anker, John; Pfister, Marc; Gotta, Verena (2024). Pharmacokinetics-Based Pediatric Dose Evaluation and Optimization Using Saliva - A Case Study. Journal of clinical pharmacology, 64(7), pp. 810-819. Wiley 10.1002/jcph.2428
Kern, Charlotte; Müller, Pie; Chaccour, Carlos; Liechti, Matthias E; Hammann, Felix; Duthaler, Urs (2023). Pharmacokinetics of ivermectin metabolites and their activity against Anopheles stephensi mosquitoes. Malaria journal, 22(1), p. 194. BioMed Central 10.1186/s12936-023-04624-0
Chaccour, Carlos; Casellas, Aina; Hammann, Felix; Ruiz-Castillo, Paula; Nicolas, Patricia; Montaña, Julia; Mael, Mary; Selvaraj, Prashant; Duthaler, Urs; Mrema, Sigilbert; Kakolwa, Mwaka; Lyimo, Issa; Okumu, Fredros; Marathe, Achla; Schürch, Roger; Elobolobo, Eldo; Sacoor, Charfudin; Saute, Francisco; Xia, Kang; Jones, Caroline; ... (2023). BOHEMIA: Broad One Health Endectocide-based Malaria Intervention in Africa-a phase III cluster-randomized, open-label, clinical trial to study the safety and efficacy of ivermectin mass drug administration to reduce malaria transmission in two African settings. Trials, 24(1), p. 128. BioMed Central 10.1186/s13063-023-07098-2
Lett, Martin J; Mehta, Hema; Keogh, Adrian; Jaeger, Tina; Jacquet, Maxime; Powell, Kate; Meier, Marie-Anne; Fofana, Isabel; Melhem, Hassan; Vosbeck, Jürg; Cathomas, Gieri; Heigl, Andres; Heim, Markus H; Burri, Emanuel; Mertz, Kirsten D; Niess, Jan Hendrik; Kollmar, Otto; Zech, Christoph J; Ivanek, Robert; Duthaler, Urs; ... (2022). Stimulatory MAIT cell antigens reach the circulation and are efficiently metabolised and presented by human liver cells. Gut, 71(12), pp. 2526-2538. BMJ Publishing Group 10.1136/gutjnl-2021-324478
Duthaler, Urs; Bachmann, Fabio; Suenderhauf, Claudia; Grandinetti, Tanja; Pfefferkorn, Florian; Haschke, Manuel; Hruz, Petr; Bouitbir, Jamal; Krähenbühl, Stephan (2022). Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel Phenotyping Cocktail Differently. Clinical pharmacokinetics, 61(7), pp. 1039-1055. Springer 10.1007/s40262-022-01119-0
Bachmann, Fabio; Duthaler, Urs; Meyer Zu Schwabedissen, Henriette E; Puchkov, Maxim; Huwyler, Jörg; Haschke, Manuel; Krähenbühl, Stephan (2021). Metamizole is a moderate cytochrome P450 inducer via the constitutive androstane receptor and a weak inhibitor of CYP1A2. Clinical pharmacology and therapeutics, 109(6), pp. 1505-1516. Wiley 10.1002/cpt.2141
Nicolas, Patricia; Kiuru, Caroline; Wagah, Martin G; Muturi, Martha; Duthaler, Urs; Hammann, Felix; Maia, Marta; Chaccour, Carlos (2021). Potential metabolic resistance mechanisms to ivermectin in Anopheles gambiae: a synergist bioassay study. Parasites & Vectors, 14(1), p. 172. BioMed Central 10.1186/s13071-021-04675-9
Scholz, Irene; Liakoni, Evangelia; Hammann, Felix; Grafinger, Katharina Elisabeth; Duthaler, Urs; Nagler, Michael; Krähenbühl, Stephan; Haschke, Manuel (2021). Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans. British journal of clinical pharmacology, 87(3), pp. 1466-1474. Wiley-Blackwell 10.1111/bcp.14553
Duthaler, Urs; Weber, Michael; Hofer, Lorenz; Chaccour, Carlos; Maia, Marta; Müller, Pie; Krähenbühl, Stephan; Hammann, Felix (2021). The pharmacokinetics and drug-drug interactions of ivermectin in Aedes aegypti mosquitoes. PLoS pathogens, 17(3), e1009382. Public Library of Science 10.1371/journal.ppat.1009382
Blaser, Lea S; Duthaler, Urs; Bouitbir, Jamal; Leuppi-Taegtmeyer, Anne B; Liakoni, Evangelia; Dolf, Reto; Mayr, Michael; Drewe, Jürgen; Krähenbühl, Stephan; Haschke, Manuel (2021). Comparative Effects of Metamizole (Dipyrone) and Naproxen on Renal Function and Prostacyclin Synthesis in Salt-Depleted Healthy Subjects - A Randomized Controlled Parallel Group Study. Frontiers in Pharmacology, 12(620635), p. 620635. Frontiers 10.3389/fphar.2021.620635
Duthaler, Urs; Leisegang, Rory; Karlsson, Mats O; Krähenbühl, Stephan; Hammann, Felix (2020). The effect of food on the pharmacokinetics of oral ivermectin. The journal of antimicrobial chemotherapy, 75(2), pp. 438-440. Oxford University Press 10.1093/jac/dkz466
Suenderhauf, Claudia; Berger, Benjamin; Puchkov, Maxim; Schmid, Yasmin; Müller, Sabine; Huwyler, Jörg; Haschke, Manuel; Krähenbühl, Stephan; Duthaler, Urs (2020). Pharmacokinetics and phenotyping properties of the Basel phenotyping cocktail combination capsule in healthy male adults. British journal of clinical pharmacology, 86(2), pp. 352-361. Wiley-Blackwell 10.1111/bcp.14157
Bachmann, Fabio; Blaser, Lea; Haschke, Manuel Martin; Krähenbühl, Stephan; Duthaler, Urs (2020). Development and validation of an LC-MS/MS method for the bioanalysis of the major metamizole metabolites in human plasma. Bioanalysis, 12(3), pp. 175-189. Future Science 10.4155/bio-2019-0251
Ziesenitz, Victoria C; Rodieux, Frédérique; Atkinson, Andrew; Borter, Carole; Bielicki, Julia A; Haschke, Manuel; Duthaler, Urs; Bachmann, Fabio; Erb, Thomas O; Gürtler, Nicolas; Holland-Cunz, Stefan; van den Anker, Johannes N; Gotta, Verena; Pfister, Marc (2019). Dose evaluation of intravenous metamizole (dipyrone) in infants and children: a prospective population pharmacokinetic study. European journal of clinical pharmacology, 75(11), pp. 1491-1502. Springer 10.1007/s00228-019-02720-2
Duthaler, Urs; Suenderhauf, Claudia; Gaugler, Stefan; Vetter, Beatrice; Krähenbühl, Stephan; Hammann, Felix (2019). Development and validation of an LC-MS/MS method for the analysis of ivermectin in plasma, whole blood, and dried blood spots using a fully automatic extraction system. Journal of pharmaceutical and biomedical analysis, 172, pp. 18-25. Elsevier 10.1016/j.jpba.2019.04.007
Leuppi-Taegtmeyer, Anne; Duthaler, Urs; Hammann, Felix; Schmid, Yasmin; Dickenmann, Michael; Amico, Patricia; Jehle, Andreas W; Kalbermatter, Stefan; Lenherr, Christoph; Meyer Zu Schwabedissen, Henriette E; Haschke, Manuel Martin; Liechti, Matthias E; Krähenbühl, Stephan (2019). Pharmacokinetics of oxycodone/naloxone and its metabolites in patients with end-stage renal disease during and between haemodialysis sessions. Nephrology, dialysis, transplantation, 34(4), pp. 692-702. Oxford University Press 10.1093/ndt/gfy285
Duthaler, Urs; Berger, Benjamin; Erb, Stefan; Battegay, Manuel; Letang, Emili; Gaugler, Stefan; Natamatungiro, Alex; Mnzava, Dorcas; Donzelli, Massimiliano; Krähenbühl, Stephan; Haschke, Manuel Martin (2018). Using dried blood spots to facilitate therapeutic drug monitoring of antiretroviral drugs in resource-poor regions. The journal of antimicrobial chemotherapy, 73(10), pp. 2729-2737. Oxford University Press 10.1093/jac/dky254
Bachmann, Fabio; Duthaler, Urs; Rudin, Deborah; Krähenbühl, Stephan; Haschke, Manuel Martin (2018). N-demethylation of N-methyl-4-aminoantipyrine, the main metabolite of metamizole. European journal of pharmaceutical sciences, 120, pp. 172-180. Elsevier 10.1016/j.ejps.2018.05.003
Berger, Benjamin; Bachmann, Fabio; Duthaler, Urs; Krähenbühl, Stephan; Haschke, Manuel Martin (2018). Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug. Frontiers in Pharmacology, 9(774), p. 774. Frontiers 10.3389/fphar.2018.00774
