Gyimesi, Gergely

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Number of items: 22.

Journal Article

Alexander, Stephen P H; Fabbro, Doriano; Kelly, Eamonn; Mathie, Alistair A; Peters, John A; Veale, Emma L; Armstrong, Jane F; Faccenda, Elena; Harding, Simon D; Davies, Jamie A; Amarosi, Laura; Anderson, Catriona M H; Beart, Philip M; Broer, Stefan; Dawson, Paul A; Gyimesi, Gergely; Hagenbuch, Bruno; Hammond, James R; Hancox, Jules C; Hershfinkel, Michal; ... (2023). The Concise Guide to PHARMACOLOGY 2023/24: Transporters. British journal of pharmacology, 180 Suppl 2, S374-S469. Wiley-Blackwell 10.1111/bph.16182

Schlosser, Pascal; Scherer, Nora; Grundner-Culemann, Franziska; Monteiro-Martins, Sara; Haug, Stefan; Steinbrenner, Inga; Uluvar, Burulça; Wuttke, Matthias; Cheng, Yurong; Ekici, Arif B; Gyimesi, Gergely; Karoly, Edward D; Kotsis, Fruzsina; Mielke, Johanna; Gomez, Maria F; Yu, Bing; Grams, Morgan E; Coresh, Josef; Boerwinkle, Eric; Köttgen, Michael; ... (2023). Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine. Nature genetics, 55(6), pp. 995-1008. Nature America 10.1038/s41588-023-01409-8

Gyimesi, Gergely; Hediger, Matthias A (2023). Transporter-Mediated Drug Delivery. Molecules, 28(3) MDPI 10.3390/molecules28031151

Augustynek, Bartlomiej; Gyimesi, Gergely; Dernič, Jan; Sallinger, Matthias; Albano, Giuseppe; Klesse, Gabriel J; Kandasamy, Palanivel; Grabmayr, Herwig; Frischauf, Irene; Fuster, Daniel G; Peinelt, Christine; Hediger, Matthias A; Bhardwaj, Rajesh (2022). Discovery of novel gating checkpoints in the Orai1 calcium channel by systematic analysis of constitutively active mutants of its paralogs and orthologs. Cell calcium, 105, p. 102616. Elsevier 10.1016/j.ceca.2022.102616

Anderegg, Manuel A; Gyimesi, Gergely; Ho, Manh Tin; Hediger, Matthias A; Fuster, Daniel G (2022). The Less Well-Known Little Brothers: The SLC9B/NHA Sodium Proton Exchanger Subfamily—Structure, Function, Regulation and Potential Drug-Target Approaches. Frontiers in physiology, 13, p. 898508. Frontiers Research Foundation 10.3389/fphys.2022.898508

Gyimesi, Gergely; Hediger, Matthias A (2022). Systematic in silico discovery of novel solute carrier-like proteins from proteomes. PLoS ONE, 17(7), e0271062. Public Library of Science 10.1371/journal.pone.0271062

Gyimesi, Gergely; Hediger, Matthias (2020). Sequence Features of Mitochondrial Transporter Protein Families. Biomolecules, 10(12) MDPI 10.3390/biom10121611

Bhardwaj, Rajesh; Lindinger, Sonja; Neuberger, Arthur; Nadezhdin, Kirill D.; Singh, Appu K.; R. Cunha, Micael; Derler, Isabella; Gyimesi, Gergely; Reymond, Jean-Louis; Hediger, Matthias A.; Romanin, Christoph; Sobolevsky, Alexander I. (2020). Inactivation-mimicking block of the epithelial calcium channel TRPV6. Science Advances, 6(48), eabe1508. American Association for the Advancement of Science 10.1126/sciadv.abe1508

Gyimesi, Gergely; Pujol-Gimenez, Jonai; Kanai, Yoshikatsu; Hediger, Matthias A. (2020). Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application. Pflügers Archiv : European journal of physiology, 472(9), pp. 1177-1206. Springer 10.1007/s00424-020-02433-x

Gyimesi, Gergely; Albano, Giuseppe; Fuster, Daniel G.; Hediger, Matthias A.; Pujol-Giménez, Jonai (2020). Correction: Unraveling the structural elements of pH sensitivity and substrate binding in the human zinc transporter SLC39A2 (ZIP2). Journal of biological chemistry, 295(13), p. 4369. American Society for Biochemistry and Molecular Biology 10.1074/jbc.AAC120.013245

Stergachis, Andrew B; Pujol Gimenez, Jonai; Gyimesi, Gergely; Fuster, Daniel Guido; Albano, Giuseppe; Troxler, Marina; Picker, Jonathan; Rosenberg, Paul A; Bergin, Ann; Peters, Jurriaan; Moufawad El Achkar, Christelle; Harini, Chellamani; Manzi, Shannon; Rotenberg, Alexander; Hediger, Matthias A.; Rodan, Lance H (2019). Recurrent SLC1A2 variants cause epilepsy via a dominant negative mechanism. Annals of neurology, 85(6), pp. 921-926. Wiley-Blackwell 10.1002/ana.25477

Gyimesi, Gergely; Albano, Giuseppe; Fuster, Daniel Guido; Hediger, Matthias A; Pujol Gimenez, Jonai (2019). Unraveling the structural elements of pH sensitivity and substrate binding in the human zinc transporter SLC39A2 (ZIP2). Journal of biological chemistry, 294(20), pp. 8046-8063. American Society for Biochemistry and Molecular Biology 10.1074/jbc.RA118.006113

Bulla, M.; Gyimesi, Gergely; Kim, JH.; Bhardwaj, Rajesh; Hediger, Matthias; Frieden, M.; Demaurex, N. (2019). ORAI1 channel gating and selectivity is differentially altered by natural mutations in the first or third transmembrane domain. Journal of physiology, 597(2), pp. 561-582. Wiley-Blackwell 10.1113/JP277079

Kandasamy, Palanivel; Gyimesi, Gergely; Kanai, Yoshikatsu; Hediger, Matthias (2018). Amino acid transporters revisited: New views in health and disease. Trends in biochemical sciences, 43(10), pp. 752-789. Elsevier Current Trends 10.1016/j.tibs.2018.05.003

Pujol Gimenez, Jonai; Hediger, Matthias; Gyimesi, Gergely (2017). A novel proton transfer mechanism in the SLC11 family of divalent metal ion transporters. Scientific Reports, 7(1), p. 6194. Nature Publishing Group 10.1038/s41598-017-06446-y

Simonin, Alexandre; Montalbetti, Nicolas; Gyimesi, Gergely; Pujol Gimenez, Jonai; Hediger, Matthias (2015). The Hydroxyl Side Chain of a Highly Conserved Serine Residue Is Required for Cation Selectivity and Substrate Transport in the Glial Glutamate Transporter GLT-1/SLC1A2. Journal of biological chemistry, 290(51), pp. 30464-30474. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M115.689836

César-Razquin, Adrián; Snijder, Berend; Frappier-Brinton, Tristan; Isserlin, Ruth; Gyimesi, Gergely; Bai, Xiaoyun; Reithmeier, Reinhart A; Hepworth, David; Hediger, Matthias; Edwards, Aled M; Superti-Furga, Giulio (2015). A Call for Systematic Research on Solute Carriers. Cell, 162(3), pp. 478-487. Cell Press 10.1016/j.cell.2015.07.022

Simonin, Céline; Awale, Mahendra; Brand, Michael; van Deursen, Ruud; Schwartz, Julian; Fine, Michael; Kovacs, Gergely; Häfliger, Pascal; Gyimesi, Gergely; Sithampari, Abilashan; Charles, Roch-Philippe; Hediger, Matthias; Reymond, Jean-Louis (2015). Optimization of TRPV6 Calcium Channel Inhibitors Using a 3D Ligand-Based Virtual Screening Method. Angewandte Chemie (International ed.), 54(49), pp. 14748-14752. Wiley-VCH 10.1002/anie.201507320

Book Section

Peng, J-B; Suzuki, Y; Gyimesi, Gergely; Hediger, Matthias (2017). TRPV5 and TRPV6 calcium-selective channels. In: Ashot Kozak, Juliusz; Putney, James Jr. (eds.) Calcium Entry Channels in Non-Excitable Cells. Methods in Signal Transduction Series (pp. 241-274). CRC Press

Working Paper

Gyimesi, Gergely; Hediger, Matthias A (3 November 2022). Transporter-Mediated Drug Delivery (Preprints). MDPI 10.20944/preprints202211.0062.v1

Gyimesi, Gergely; Hediger, Matthias A. (2021). Systematic in silico discovery of novel solute carrier-like proteins from proteomes (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2021.11.19.469292

Augustynek, Bartlomiej; Gyimesi, Gergely; Dernic, Jan; Sallinger, Matthias; Albano, Giuseppe; Klesse, Gabriel J.; Kandasamy, Palanivel; Grabmayr, Herwig; Frischauf, Irene; Fuster, Daniel G.; Peinelt, Christine; Hediger, Matthias A.; Bhardwaj, Rajesh (2021). Dissecting gating mechanisms of Orai calcium channel paralogs using constitutively active Orai mutants that mimic STIM1-gated state (In Press) (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2021.10.26.465861

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