Harder, Daniel

Harder, Daniel; Ritzmann, Noah; Ucurum Fotiadis, Zöhre; Müller, Daniel J; Fotiadis, Dimitrios (2024). Light Color-Controlled pH-Adjustment of Aqueous Solutions Using Engineered Proteoliposomes. Advanced science, 11(15), e2307524. Wiley 10.1002/advs.202307524

Kantipudi, Satish; Harder, Daniel; Fotiadis, Dimitrios (2023). Characterization of substrates and inhibitors of the human heterodimeric transporter 4F2hc-LAT1 using purified protein and the scintillation proximity radioligand binding assay. Frontiers in physiology, 14(1148055), p. 1148055. Frontiers Research Foundation 10.3389/fphys.2023.1148055

Stauffer, Mirko; Ucurum, Zöhre; Harder, Daniel; Fotiadis, Dimitrios (2021). Engineering and functional characterization of a proton-driven β-lactam antibiotic translocation module for bionanotechnological applications. Scientific reports, 11(1), p. 17205. Springer Nature 10.1038/s41598-021-96298-4

Kantipudi, Satish; Harder, Daniel; Bonetti, Sara; Fotiadis, Dimitrios; Jeckelmann, Jean-Marc (2021). Pichia pastoris and the Recombinant Human Heterodimeric Amino Acid Transporter 4F2hc-LAT1: From Clone Selection to Pure Protein. Methods and protocols, 4(3) MDPI AG 10.3390/mps4030051

Stauffer, Mirko; Hirschi, Stephan; Ucurum, Zöhre; Harder, Daniel; Schlesinger, Ramona; Fotiadis, Dimitrios (2020). Engineering and Production of the Light-Driven Proton Pump Bacteriorhodopsin in 2D Crystals for Basic Research and Applied Technologies. Methods and protocols, 3(3) MDPI AG 10.3390/mps3030051

Lemmin, Thomas; Kalbermatter, David; Harder, Daniel; Plattet, Philippe; Fotiadis, Dimitrios (2020). Structures and dynamics of the novel S1/S2 protease cleavage site loop of the SARS-CoV-2 spike glycoprotein. Journal of structural biology: X, 4, p. 100038. Elsevier 10.1016/j.yjsbx.2020.100038

Pfreundschuh, Moritz; Harder, Daniel; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José; Müller, Daniel J (2017). Detecting Ligand-Binding Events and Free Energy Landscape while Imaging Membrane Receptors at Subnanometer Resolution. Nano letters, 17(5), pp. 3261-3269. American Chemical Society 10.1021/acs.nanolett.7b00941

Harder, Daniel; Hirschi, Stephan; Ucurum Fotiadis, Zöhre; Goers, Roland; Meier, Wolfgang; Müller, Daniel J; Fotiadis, Dimitrios José (2016). Engineering a Chemical Switch into the Light-driven Proton Pump Proteorhodopsin by Cysteine Mutagenesis and Thiol Modification. Angewandte Chemie (International ed.), 55(31), pp. 8846-8849. Wiley-VCH 10.1002/anie.201601537

Hirschi, Stephan; Stauffer, Mirko; Harder, Daniel; Müller, Daniel J; Meier, Wolfgang; Fotiadis, Dimitrios José (2016). Engineering and Assembly of Protein Modules into Functional Molecular Systems. CHIMIA, 70(6), pp. 398-401. Schweizerische Chemische Gesellschaft 10.2533/chimia.2016.398

Boggavarapu, Venkata Ravi Naga Rajendr; Hirschi, Stephan; Harder, Daniel; Meury, Marcel; Ucurum Fotiadis, Zöhre; Bergeron, Marc; Fotiadis, Dimitrios José (2016). Purification of Human and Mammalian Membrane Proteins Expressed in Xenopus laevis Frog Oocytes for Structural Studies. In: Mus-Veteau, Isabelle (ed.) Heterologous Expression of Membrane Proteins. Methods and Protocols. Methods in Molecular Biology: Vol. 1432 (pp. 223-242). New York: Springer 10.1007/978-1-4939-3637-3_14

Petrosyan, Rafayel; Bippes, Christian A; Walheim, Stefan; Harder, Daniel; Fotiadis, Dimitrios José; Schimmel, Thomas; Alsteens, David; Müller, Daniel J (2015). Single-molecule force spectroscopy of membrane proteins from membranes freely spanning across nanoscopic pores. Nano letters, 15(5), pp. 3624-3633. American Chemical Society 10.1021/acs.nanolett.5b01223

Boggavarapu, Venkata Ravi Naga Rajendr; Jeckelmann, Jean-Marc; Harder, Daniel; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José (2015). Role of electrostatic interactions for ligand recognition and specificity of peptide transporters. BMC biology, 13(58), p. 58. BioMed Central 10.1186/s12915-015-0167-8

Meury, Marcel; Costa Torres, Meritxell; Harder, Daniel; Stauffer, Mirko; Jeckelmann, Jean-Marc; Brühlmann, Béla; Rosell, Albert; Ilgü, Hüseyin; Kovar, Karin; Palacín, Manuel; Fotiadis, Dimitrios José (2014). Detergent-induced stabilization and improved 3D map of the human heteromeric amino acid transporter 4F2hc-LAT2. PLoS ONE, 9(10), e109882. Public Library of Science 10.1371/journal.pone.0109882

Jeckelmann, Jean-Marc; Harder, Daniel; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José (2014). 2D and 3D crystallization of a bacterial homologue of human vitamin C membrane transport proteins. Journal of structural biology, 188(1), pp. 87-91. Elsevier 10.1016/j.jsb.2014.08.004

Bippes, Christian A.; Ge, Lin; Meury, Marcel; Harder, Daniel; Ucurum, Zöhre; Daniel, Hannelore; Fotiadis, Dimitrios; Müller, Daniel J. (2013). Peptide transporter DtpA has two alternate conformations, one of which is promoted by inhibitor binding. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 110(42), E3978-E3986. National Academy of Sciences NAS 10.1073/pnas.1312959110

Boggavarapu, Rajendra; Jeckelmann, Jean-Marc; Harder, Daniel; Schneider, Philipp; Ucurum, Zöhre; Hediger, Matthias; Fotiadis, Dimitrios (2013). Expression, purification and low-resolution structure of human vitamin C transporter SVCT1 (SLC23A1). PLoS ONE, 8(10), e76427. Public Library of Science 10.1371/journal.pone.0076427

Harder, Daniel; Fotiadis, Dimitrios (2012). Measuring substrate binding and affinity of purified membrane transport proteins using the scintillation proximity assay. Nature protocols, 7(9), pp. 1569-78. London: Nature Publishing Group 10.1038/nprot.2012.090

Jeckelmann, Jean-Marc; Harder, Daniel; Mari, Stefania A; Meury, Marcel; Ucurum, Zöhre; Müller, Daniel J; Erni, Bernhard; Fotiadis, Dimitrios (2011). Structure and function of the glucose PTS transporter from Escherichia coli. Journal of structural biology, 176(3), pp. 395-403. San Diego, Calif.: Elsevier 10.1016/j.jsb.2011.09.012

Meury, Marcel; Harder, Daniel; Ucurum, Zöhre; Boggavarapu, Rajendra; Jeckelmann, Jean-Marc; Fotiadis, Dimitrios (2011). Structure determination of channel and transport proteins by high-resolution microscopy techniques. Biological chemistry, 392(1-2), pp. 143-50. Berlin: Walter de Gruyter 10.1515/BC.2011.004

Casagrande, Fabio; Harder, Daniel; Schenk, Andreas; Meury, Marcel; Ucurum, Zohre; Engel, Andreas; Weitz, Dietmar; Daniel, Hannelore; Fotiadis, Dimitrios (2009). Projection structure of DtpD (YbgH), a prokaryotic member of the peptide transporter family. Journal of molecular biology, 394(4), pp. 708-17. Amsterdam: Elsevier 10.1016/j.jmb.2009.09.048

Harder, Daniel; Stolz, Jürgen; Casagrande, Fabio; Obrdlik, Petr; Weitz, Dietmar; Fotiadis, Dimitrios; Daniel, Hannelore (2008). DtpB (YhiP) and DtpA (TppB, YdgR) are prototypical proton-dependent peptide transporters of Escherichia coli. FEBS journal, 275(13), pp. 3290-8. Oxford: Wiley-Blackwell 10.1111/j.1742-4658.2008.06477.x

Weitz, Dietmar; Harder, Daniel; Casagrande, Fabio; Fotiadis, Dimitrios; Obrdlik, Petr; Kelety, Bela; Daniel, Hannelore (2007). Functional and structural characterization of a prokaryotic peptide transporter with features similar to mammalian PEPT1. Journal of biological chemistry, 282(5), pp. 2832-9. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M604866200