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Hoffet, Michelle Salomé; Tomov, Nikola S.; Hupp, Sabrina; Mitchell, Timothy J; Iliev, Asparouh I. (2024). Glucose and Oxygen Levels Modulate the Pore-Forming Effects of Cholesterol-Dependent Cytolysin Pneumolysin from Streptococcus pneumoniae. Toxins, 16(6) MDPI 10.3390/toxins16060232
Müller, Annelies; Lekhuleni, Cebile; Hupp, Sabrina; du Plessis, Mignon; Holivololona, Lalaina; Babiichuk, Eduard; Leib, Stephen L.; Grandgirard, Denis; Iliev, Asparouh I.; von Gottberg, Anne; Hathaway, Lucy J. (2023). Meningitis-associated pneumococcal serotype 8, ST 53, strain is hypervirulent in a rat model and has non-haemolytic pneumolysin which can be attenuated by liposomes. Frontiers in cellular and infection microbiology, 12 Frontiers 10.3389/fcimb.2022.1106063
Hupp, Sabrina; Förtsch, Christina; Graber, Franziska; Mitchell, Timothy J; Iliev, Asparouh I (2022). Pneumolysin boosts the neuroinflammatory response to Streptococcus pneumoniae through enhanced endocytosis. Nature communications, 13(1), p. 5032. Nature Publishing Group 10.1038/s41467-022-32624-2
Baronti, Dario; Tomov, Nikola; Hupp, Sabrina; Mitchell, Timothy J; Iliev, Asparouh Iliev (2022). Dendritic spine loss deep in the neocortex and dendrite distortion with diffusion disturbances occur early in experimental pneumococcal meningitis. Frontiers in neuroscience, 16(912445), p. 912445. Frontiers Research Foundation 10.3389/fnins.2022.912445
Hupp, Sabrina; Tomov, Nikola Stefanov; Bischoff, Carolin; Baronti, Dario; Iliev, Asparouh I. (2021). Easy to build cost-effective acute brain slice incubation system for parallel analysis of multiple treatment conditions. Journal of neuroscience methods, 366, p. 109405. Elsevier 10.1016/j.jneumeth.2021.109405
Hupp, Sabrina; Iliev, Asparouh I. (2020). CSF-1 receptor inhibition as a highly effective tool for depletion of microglia in mixed glial cultures. Journal of neuroscience methods, 332, p. 108537. Elsevier 10.1016/j.jneumeth.2019.108537
Spes, Katarina Špiranec; Hupp, Sabrina; Werner, Franziska; Koch, Franziska; Völker, Katharina; Krebes, Lisa; Kämmerer, Ulrike; Heinze, Katrin G; Braunger, Barbara M; Kuhn, Michaela (2020). Natriuretic Peptides Attenuate Retinal Pathological Neovascularization Via Cyclic GMP Signaling in Pericytes and Astrocytes. Arteriosclerosis, thrombosis, and vascular biology, 40(1), pp. 159-174. Lippincott Williams & Wilkins 10.1161/ATVBAHA.119.313400
Hupp, Sabrina; Grandgirard, Denis; Mitchell, Timothy J.; Leib, Stephen; Hathaway, Lucy Jane; Iliev, Asparouh I. (2019). Pneumolysin and the bacterial capsule of Streptococcus pneumoniae cooperatively inhibit taxis and motility of microglia. Journal of neuroinflammation, 16(1), p. 105. BioMed Central 10.1186/s12974-019-1491-7
Maurer, Jana; Hupp, Sabrina; Pillich, Helena; Mitchell, Timothy J; Chakraborty, Trinad; Iliev, Asparouh I (2018). Missing elimination via membrane vesicle shedding contributes to the diminished calcium sensitivity of listeriolysin O. Scientific Reports, 8(1), p. 15846. Nature Publishing Group 10.1038/s41598-018-34031-4
Hupp, Sabrina; Ribes, Sandra; Seele, Jana; Bischoff, Carolin; Förtsch, Christina; Maier, Elke; Benz, Roland; Mitchell, Timothy J; Nau, Roland; Iliev, Asparouh Iliev (2017). Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation. British journal of pharmacology, 174(23), pp. 4295-4307. Wiley-Blackwell 10.1111/bph.14027
Maurer, Jana; Hupp, Sabrina; Bischoff, Carolin; Foertsch, Christina; Mitchell, Timothy J; Chakraborty, Trinad; Iliev, Asparouh Iliev (2017). Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes. Toxins, 9(1) MDPI 10.3390/toxins9010034
