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Preti, Barbara; Suchankova, Anna; Deganutti, Giuseppe; Leuenberger, Michele; Barkan, Kerry; Manulak, Iga; Huang, Xianglin; Carvalho, Sabrina; Ladds, Graham; Lochner, Martin (2022). Discovery and Structure-Activity Relationship Studies of Novel Adenosine A1 Receptor-Selective Agonists. Journal of medicinal chemistry, 65(21), pp. 14864-14890. American Chemical Society 10.1021/acs.jmedchem.2c01414
Wall, Mark J; Hill, Emily; Huckstepp, Robert; Barkan, Kerry; Deganutti, Giuseppe; Leuenberger, Michele; Preti, Barbara; Winfield, Ian; Carvalho, Sabrina; Suchankova, Anna; Wei, Haifeng; Safitri, Dewi; Huang, Xianglin; Imlach, Wendy; La Mache, Circe; Dean, Eve; Hume, Cherise; Hayward, Stephanie; Oliver, Jess; Zhao, Fei-Yue; ... (2022). Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression. Nature communications, 13(1), p. 4150. Nature Publishing Group 10.1038/s41467-022-31652-2
Deganutti, Giuseppe; Barkan, Kerry; Preti, Barbara; Leuenberger, Michele; Wall, Mark; Frenguelli, Bruno G.; Lochner, Martin; Ladds, Graham; Reynolds, Christopher A. (2021). Deciphering the Agonist Binding Mechanism to the Adenosine A1 Receptor. ACS pharmacology & translational science, 4(1), pp. 314-326. ACS Publications 10.1021/acsptsci.0c00195
Knight, Anthony; Hemmings, Jennifer L.; Winfield, Ian; Leuenberger, Michele; Frattini, Eugenia; Frenguelli, Bruno G.; Dowell, Simon J.; Lochner, Martin; Ladds, Graham (2020). Correction to Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity. Journal of medicinal chemistry, 63(18), p. 10531. American Chemical Society 10.1021/acs.jmedchem.0c01416
Knight, Anthony; Hemmings, Jennifer Luise; Winfield, Ian; Leuenberger, Michele; Frattini, Eugenia; Frenguelli, Bruno G.; Dowell, Simon J.; Lochner, Martin; Ladds, Graham (2016). Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity. Journal of medicinal chemistry, 59(3), pp. 947-964. American Chemical Society 10.1021/acs.jmedchem.5b01402
Preti, Barbara; Suchankova, Anna; Barkan, Kerry; Leuenberger, Michele; Ladds, Graham; Lochner, Martin (July 2021). Structure-activity relationship study to find novel potent and selective adenosine A1 receptor agonists [MC-125]. CHIMIA, 75(7/8), p. 667. Schweizerische Chemische Gesellschaft
Preti, Barbara; Leuenberger, Michele; Lochner, Martin; Frenguelli, Bruno G.; Ladds, Graham (6 September 2019). Development of Molecular Tools for the Cellular Study of Adenosine A1 Receptors. CHIMIA, 73(7/8). Schweizerische Chemische Gesellschaft
Lochner, Martin; Leuenberger, Michele; Preti, Barbara; Tesfazghi, Bereket; Bartlome, Pascal; Frenguelli, Bruno G.; Barkan-Bulman, Kerry; Ladds, Graham (10 September 2018). Development of Molecular Tools for the Study of Adenosine A1 Receptors (Unpublished). In: 7th RSC/SCI Symposium on GPCRs in Medicinal Chemistry. Verona. 10.-12.09.2018.
Preti, Barbara; Tesfazghi, Bereket; Bartlome, Pascal; Leuenberger, Michele; Frenguelli, Bruno G.; Ladds, Graham; Lochner, Martin (7 September 2018). Molecular Tools for the Cellular Study of Adenosine A1 Receptors. CHIMIA, 72(7/8). Schweizerische Chemische Gesellschaft
Lochner, Martin; Hemmings, Jennifer Luise; Leuenberger, Michele; Meyer, Jonas; Bartlome, Pascal; Perozzo, Alyssa Victoria; Frenguelli, Bruno G.; Winfield, Ian; Ladds, Graham (12 February 2017). Molecular Tools for the Cellular Study of Adenosine A1 Receptors (Unpublished). In: GDCh/SCS conference on Frontiers in Medicinal Chemistry. Bern. 12.-15.02.2017.
Lochner, Martin; Hemmings, Jennifer Luise; Knight, Anthony; Frenguelli, Bruno G.; Ladds, Graham (15 June 2015). Development of small molecular tools for the cellular study of adenosine receptors (Unpublished). In: Challenges in Chemical Biology (ISACS16). ETH Zürich, Hönggerberg, Switzerland. 15.06.-18.06.2015.
Hemmings, Jennifer Luise; Ladds, Graham; Knight, Anthony; Frenguelli, Bruno G.; Lochner, Martin (August 2013). Synthesis of novel fluorescent agonists, with selectivity for the A1 adenosine receptor. CHIMIA, 67(7/8), p. 532. Schweizerische Chemische Gesellschaft
Hill, Emily; Huang, Xianglin; Del Popolo, Ivana; La Mache, Circe; Lochner, Martin; Ladds, Graham; Frenguelli, Bruno G.; Wall, Mark J. (2 December 2022). Species-dependent actions of the Goαb selective adenosine A1 receptor agonist BnOCPA (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2022.12.02.518704
Wall, Mark J.; Hill, Emily; Huckstepp, Robert; Barkan, Kerry; Deganutti, Giuseppe; Leuenberger, Michele; Preti, Barbara; Winfield, Ian; Carvalho, Sabrina; Suchankova, Anna; Wei, Haifeng; Safitri, Dewi; Huang, Xianglin; Imlach, Wendy; La Mache, Circe; Dean, Eve; Hume, Cherise; Hayward, Stephanie; Oliver, Jess; Zhao, Fei-Yue; ... (27 April 2022). Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2020.04.04.023945
Deganutti, Giuseppe; Barkan, Kerry; Preti, Barbara; Leuenberger, Michele; Wall, Mark; Frenguelli, Bruno G.; Lochner, Martin; Ladds, Graham; Reynolds, Christopher A. (22 October 2020). Deciphering the Agonist Binding Mechanism to the Adenosine A1 Receptor (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2020.10.22.350827
