Legler, Daniel F

Ruef, Nora; Martínez Magdaleno, Jose; Ficht, Xenia; Purvanov, Vladimir; Palayret, Matthieu; Wissmann, Stefanie; Pfenninger, Petra; Stolp, Bettina; Thelen, Flavian; Barreto de Albuquerque, Juliana; Germann, Philipp; Sharpe, James; Abe, Jun; Legler, Daniel F; Stein, Jens V (2023). Exocrine gland-resident memory CD8+ T cells use mechanosensing for tissue surveillance. Science immunology, 8(90), eadd5724. American Association for the Advancement of Science 10.1126/sciimmunol.add5724

Garcia-Seyda, Nicolas; Song, Solene; Seveau de Noray, Valentine; David-Broglio, Luc; Matti, Christoph; Artinger, Marc; Dupuy, Florian; Biarnes-Pelicot, Martine; Valignat, Marie-Pierre; Legler, Daniel F; Bajénoff, Marc; Theodoly, Olivier (2023). Naive T lymphocytes chemotax long distance to CCL21 but not to a source of bioactive S1P. iScience, 26(10), p. 107695. Elsevier 10.1016/j.isci.2023.107695

Artinger, Marc; Gerken, Oliver J; Legler, Daniel F (2023). Heparin Specifically Interacts with Basic BBXB Motifs of the Chemokine CCL21 to Define CCR7 Signaling. International journal of molecular sciences, 24(2) MDPI 10.3390/ijms24021670

Sigmund, Elena C; Bauer, Aline; Jakobs, Barbara D; Tatliadim, Hazal; Tacconi, Carlotta; Thelen, Marcus; Legler, Daniel F; Halin, Cornelia (2023). Reassessing the adrenomedullin scavenging function of ACKR3 in lymphatic endothelial cells. PLoS ONE, 18(5), e0285597. Public Library of Science 10.1371/journal.pone.0285597

Melgrati, Serena; Gerken, Oliver J; Artinger, Marc; Radice, Egle; Szpakowska, Martyna; Chevigné, Andy; D'Uonnolo, Giulia; Antonello, Paola; Thelen, Sylvia; Pelczar, Pawel; Legler, Daniel F; Thelen, Marcus (2023). GPR182 is a broadly scavenging atypical chemokine receptor influencing T-independent immunity. Frontiers in immunology, 14(1242531), p. 1242531. Frontiers Research Foundation 10.3389/fimmu.2023.1242531

Rossatti, Pascal; Redpath, Gregory M I; Ziegler, Luca; Samson, Guerric P B; Clamagirand, Camille D; Legler, Daniel F; Rossy, Jérémie (2022). Rapid increase in transferrin receptor recycling promotes adhesion during T cell activation. BMC biology, 20(1), p. 189. BioMed Central 10.1186/s12915-022-01386-0

Artinger, Marc; Gerken, Oliver J; Purvanov, Vladimir; Legler, Daniel F (2022). Distinct Fates of Chemokine and Surrogate Molecule Gradients: Consequences for CCR7-Guided Dendritic Cell Migration. Frontiers in immunology, 13, p. 913366. Frontiers Research Foundation 10.3389/fimmu.2022.913366

Patel, Monica; Matti, Christoph; Grimsey, Natasha L; Legler, Daniel F; Javitch, Jonathan A; Finlay, David B; Glass, Michelle (2022). Delineating the interactions between the cannabinoid CB2 receptor and its regulatory effectors; β-arrestins and GPCR kinases. British journal of pharmacology, 179(10), pp. 2223-2239. Wiley 10.1111/bph.15748

Gerken, Oliver J; Artinger, Marc; Legler, Daniel F (2022). Shifting CCR7 towards Its Monomeric Form Augments CCL19 Binding and Uptake. Cells, 11(9) MDPI 10.3390/cells11091444

Friess, Mona C; Kritikos, Ioannis; Schineis, Philipp; Medina-Sanchez, Jessica Danielly; Gkountidi, Anastasia-Olga; Vallone, Angela; Sigmund, Elena C; Schwitter, Corina; Vranova, Martina; Matti, Christoph; Arasa, Jorge; Saygili Demir, Cansaran; Bovay, Esther; Proulx, Steven T; Tomura, Michio; Rot, Antal; Legler, Daniel F; Petrova, Tatiana V; Halin, Cornelia (2022). Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics. Cell reports, 38(5), p. 110334. Cell Press 10.1016/j.celrep.2022.110334

Seumen, Clovis H T; Tomasiunaite, Urte; Legler, Daniel F; Hauck, Christof R (2021). Elimination of negative feedback in TLR signalling allows rapid and hypersensitive detection of microbial contaminants. Scientific reports, 11(1), p. 24414. Springer Nature 10.1038/s41598-021-03618-9

Phan, Truong San; Schink, Leonhard; Mann, Jasmin; Merk, Verena M; Zwicky, Pascale; Mundt, Sarah; Simon, Dagmar; Kulms, Dagmar; Abraham, Susanne; Legler, Daniel F; Noti, Mario; Brunner, Thomas (2021). Keratinocytes control skin immune homeostasis through de novo-synthesized glucocorticoids. Science Advances, 7(5) American Association for the Advancement of Science 10.1126/sciadv.abe0337

Cosgrove, Jason; Novkovic, Mario; Albrecht, Stefan; Pikor, Natalia B; Zhou, Zhaoukun; Onder, Lucas; Mörbe, Urs; Cupovic, Jovana; Miller, Helen; Alden, Kieran; Thuery, Anne; O'Toole, Peter; Pinter, Rita; Jarrett, Simon; Taylor, Emily; Venetz, Daniel; Heller, Manfred; Uguccioni, Mariagrazia; Legler, Daniel F; Lacey, Charles J; ... (2020). B cell zone reticular cell microenvironments shape CXCL13 gradient formation. Nature Communications, 11(1), p. 3677. Springer Nature 10.1038/s41467-020-17135-2

Laufer, Julia M; Lyck, Ruth; Legler, Daniel F (2018). ZAP70 expression enhances chemokine-driven chronic lymphocytic leukemia cell migration and arrest by valency regulation of integrins. FASEB journal, 32(9), pp. 4824-4835. Federation of American Societies for Experimental Biology 10.1096/fj.201701452RR

Ackerknecht, Markus; Hauser, Mark A; Legler, Daniel F; Stein, Jens Volker (2015). In vivo TCR Signaling in CD4(+) T Cells Imprints a Cell-Intrinsic, Transient Low-Motility Pattern Independent of Chemokine Receptor Expression Levels, or Microtubular Network, Integrin, and Protein Kinase C Activity. Frontiers in immunology, 6, p. 297. Frontiers Research Foundation 10.3389/fimmu.2015.00297

Nachbur, Ueli; Kassahn, Daniela; Yousefi, Shida; Legler, Daniel F; Brunner, Thomas (2006). Posttranscriptional regulation of Fas (CD95) ligand killing activity by lipid rafts. Blood, 107(7), pp. 2790-6. Washington, D.C.: American Society of Hematology 10.1182/blood-2005-07-2744