Modlin, Robert L

Gruber, Thomas; Kremenovic, Mirela; Sadozai, Hassan; Rombini, Nives; Baeriswyl, Lukas; Maibach, Fabienne; Modlin, Robert L; Gilliet, Michel; von Werdt, Diego; Hunger, Robert E.; Jafari, S. Morteza Seyed; Parisi, Giulia; Abril-Rodriguez, Gabriel; Ribas, Antoni; Schenk, Mirjam (2020). IL-32γ potentiates tumor immunity in melanoma. JCI insight, 5(18) JCI Insight 10.1172/jci.insight.138772

Keegan, Caroline; Krutzik, Stephan; Schenk, Mirjam; Scumpia, Philip O; Lu, Jing; Pang, Yan Ling Joy; Russell, Brandon S; Lim, Kok Seong; Shell, Scarlet; Prestwich, Erin; Su, Dan; Elashoff, David; Hershberg, Robert M; Bloom, Barry R; Belisle, John T; Fortune, Sarah; Dedon, Peter C; Pellegrini, Matteo; Modlin, Robert L (2018). Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network. Journal of immunology, 200(9), pp. 3244-3258. American Association of Immunologists 10.4049/jimmunol.1701733

Schenk, Mirjam; Mahapatra, Sebabrata; Le, Phuonganh; Kim, Hee Jin; Choi, Aaron W; Brennan, Patrick J; Belisle, John T; Modlin, Robert L (2016). Human NOD2 Recognizes Structurally Unique Muramyl Dipeptides from Mycobacterium leprae. Infection and immunity, 84(9), pp. 2429-2438. American Society for Microbiology 10.1128/IAI.00334-16

Realegeno, Susan; Kelly-Scumpia, Kindra M; Dang, Angeline Tilly; Lu, Jing; Teles, Rosane; Liu, Philip T; Schenk, Mirjam; Lee, Ernest Y; Schmidt, Nathan W; Wong, Gerard C L; Sarno, Euzenir N; Rea, Thomas H; Ochoa, Maria T; Pellegrini, Matteo; Modlin, Robert L (2016). S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages. PLoS pathogens, 12(6), e1005705. Public Library of Science 10.1371/journal.ppat.1005705

Cappuccio, Antonio; Zollinger, Raphaël; Schenk, Mirjam; Walczak, Aleksandra; Servant, Nicolas; Barillot, Emmanuel; Hupé, Philippe; Modlin, Robert L; Soumelis, Vassili (2015). Combinatorial code governing cellular responses to complex stimuli. Nature communications, 6(6847), p. 6847. Nature Publishing Group 10.1038/ncomms7847

Montoya, Dennis; Inkeles, Megan S; Liu, Phillip T; Realegeno, Susan; Teles, Rosane M B; Vaidya, Poorva; Munoz, Marcos A; Schenk, Mirjam; Swindell, William R; Chun, Rene; Zavala, Kathryn; Hewison, Martin; Adams, John S; Horvath, Steve; Pellegrini, Matteo; Bloom, Barry R; Modlin, Robert L (2014). IL-32 is a molecular marker of a host defense network in human tuberculosis. Science translational medicine, 6(250), 250ra114. American Association for the Advancement of Science 10.1126/scitranslmed.3009546

Schenk, Mirjam; Fabri, Mario; Krutzik, Stephan R; Lee, Delphine J; Vu, David M; Sieling, Peter A; Montoya, Dennis; Liu, Philip T; Modlin, Robert L (2014). Interleukin-1β triggers the differentiation of macrophages with enhanced capacity to present mycobacterial antigen to T cells. Immunology, 141(2), pp. 174-180. Wiley-Blackwell 10.1111/imm.12167

Teles, Rosane M B; Graeber, Thomas G; Krutzik, Stephan R; Montoya, Dennis; Schenk, Mirjam; Lee, Delphine J; Komisopoulou, Evangelia; Kelly-Scumpia, Kindra; Chun, Rene; Iyer, Shankar S; Sarno, Euzenir N; Rea, Thomas H; Hewison, Martin; Adams, John S; Popper, Stephen J; Relman, David A; Stenger, Steffen; Bloom, Barry R; Cheng, Genhong and Modlin, Robert L (2013). Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science, 339(6126), pp. 1448-1453. American Association for the Advancement of Science 10.1126/science.1233665

Chung, Andrew W; Sieling, Peter A; Schenk, Mirjam; Teles, Rosane M B; Krutzik, Stephan R; Hsu, Daniel K; Liu, Fu-Tong; Sarno, Euzenir N; Rea, Thomas H; Stenger, Steffen; Modlin, Robert L; Lee, Delphine J (2013). Galectin-3 regulates the innate immune response of human monocytes. Journal of infectious diseases, 207(6), pp. 947-956. Oxford University Press 10.1093/infdis/jis920

Parvatiyar, Kislay; Zhang, Zhiqiang; Teles, Rosane M; Ouyang, Songying; Jiang, Yan; Iyer, Shankar S; Zaver, Shivam A; Schenk, Mirjam; Zeng, Shang; Zhong, Wenwan; Liu, Zhi-Jie; Modlin, Robert L; Liu, Yong-jun; Cheng, Genhong (2012). The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Nature immunology, 13(12), pp. 1155-1161. Nature Publishing Group 10.1038/ni.2460

Schenk, Mirjam; Krutzik, Stephan R; Sieling, Peter A; Lee, Delphine J; Teles, Rosane M B; Ochoa, Maria Teresa; Komisopoulou, Evangelia; Sarno, Euzenir N; Rea, Thomas H; Graeber, Thomas G; Kim, Soohyun; Cheng, Genhong; Modlin, Robert L (2012). NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nature medicine, 18(4), pp. 555-563. Nature Publishing Group 10.1038/nm.2650

Fabri, Mario; Stenger, Steffen; Shin, Dong-Min; Yuk, Jae-Min; Liu, Philip T; Realegeno, Susan; Lee, Hye-Mi; Krutzik, Stephan R; Schenk, Mirjam; Sieling, Peter A; Teles, Rosane; Montoya, Dennis; Iyer, Shankar S; Bruns, Heiko; Lewinsohn, David M; Hollis, Bruce W; Hewison, Martin; Adams, John S; Steinmeyer, Andreas; Zügel, Ulrich; ... (2011). Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages. Science translational medicine, 3(104), 104ra102. American Association for the Advancement of Science 10.1126/scitranslmed.3003045

Edfeldt, Kristina; Liu, Philip T; Chun, Rene; Fabri, Mario; Schenk, Mirjam; Wheelwright, Matthew; Keegan, Caroline; Krutzik, Stephan R; Adams, John S; Hewison, Martin; Modlin, Robert L (2010). T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 107(52), pp. 22593-22598. National Academy of Sciences NAS 10.1073/pnas.1011624108

Schenk, Mirjam; Belisle, John T; Modlin, Robert L (2009). TLR2 looks at lipoproteins. Immunity, 31(6), pp. 847-849. Cell Press 10.1016/j.immuni.2009.11.008

Montoya, Dennis; Cruz, Daniel; Teles, Rosane M B; Lee, Delphine J; Ochoa, Maria Teresa; Krutzik, Stephan R; Chun, Rene; Schenk, Mirjam; Zhang, Xiaoran; Ferguson, Benjamin G; Burdick, Anne E; Sarno, Euzenir N; Rea, Thomas H; Hewison, Martin; Adams, John S; Cheng, Genhong; Modlin, Robert L (2009). Divergence of macrophage phagocytic and antimicrobial programs in leprosy. Cell host & microbe, 6(4), pp. 343-353. Cell Press 10.1016/j.chom.2009.09.002

Liu, Philip T; Schenk, Mirjam; Walker, Valencia P; Dempsey, Paul W; Kanchanapoomi, Melissa; Wheelwright, Matthew; Vazirnia, Aria; Zhang, Xiaoran; Steinmeyer, Andreas; Zügel, Ulrich; Hollis, Bruce W; Cheng, Genhong; Modlin, Robert L (2009). Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses. PLoS ONE, 4(6), e5810. Public Library of Science 10.1371/journal.pone.0005810