Rufener, Lucien

Baur, Roland; Beech, Robin; Sigel, Erwin; Rufener, Lucien (2015). Monepantel irreversibly binds to and opens Haemonchus contortus MPTL-1 and Caenorhabditis elegans ACR-20 receptors. Molecular pharmacology, 87(1), pp. 96-102. American Society for Pharmacology and Experimental Therapeutics 10.1124/mol.114.095653

Rufener, Lucien; Bedoni, Nicola; Baur, Roland; Rey, Samantha; Glauser, Dominique A.; Bouvier, Jacques; Beech, Robin; Sigel, Erwin; Puoti, Alessandro (2013). acr-23 Encodes a Monepantel-Sensitive Channel in Caenorhabditis elegans. PLoS pathogens, 9(8), e1003524. Public Library of Science 10.1371/journal.ppat.1003524

Rufener, Lucien; Baur, Roland; Kaminsky, Ronald; Mäser, Pascal; Sigel, Erwin (2010). Monepantel allosterically activates DEG-3/DES-2 channels of the gastrointestinal nematode Haemonchus contortus. Molecular pharmacology, 78(5), pp. 895-902. Bethesda, Md.: American Society for Pharmacology and Experimental Therapeutics 10.1124/mol.110.066498

Rufener, Lucien; Keiser, Jennifer; Kaminsky, Ronald; Mäser, Pascal; Nilsson, Daniel (2010). Phylogenomics of ligand-gated ion channels predicts monepantel effect. PLoS pathogens, 6(9), e1001091. San Francisco, Calif.: Public Library of Science 10.1371/journal.ppat.1001091

Rufener, Lucien; Mäser, Pascal; Roditi, Isabel; Kaminsky, Ronald (2009). Haemonchus contortus acetylcholine receptors of the DEG-3 subfamily and their role in sensitivity to monepantel. PLoS pathogens, 5(4), e1000380. San Francisco, Calif.: Public Library of Science 10.1371/journal.ppat.1000380

Rufener, Lucien; Kaminsky, Ronald; Mäser, Pascal (2009). In vitro selection of Haemonchus contortus for benzimidazole resistance reveals a mutation at amino acid 198 of beta-tubulin. Molecular and biochemical parasitology, 168(1), pp. 120-2. Amsterdam: Elsevier 10.1016/j.molbiopara.2009.07.002

Kaminsky, Ronald; Ducray, Pierre; Jung, Martin; Clover, Ralph; Rufener, Lucien; Bouvier, Jacques; Schorderet Weber, Sandra; Wenger, Andre; Wieland-Berghausen, Susanne; Goebel, Thomas; Gauvry, Noelle; Pautrat, François; Skripsky, Thomas; Froelich, Olivier; Komoin-Oka, Clarisse; Westlund, Bethany; Sluder, Ann; Mäser, Pascal (2008). A new class of anthelmintics effective against drug-resistant nematodes. Nature, 452(7184), pp. 176-180. London: Macmillan Journals Ltd. 10.1038/nature06722