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Xu, Yanning; Derakhshan, Arash; Hysaj, Ola; Wildisen, Lea; Ittermann, Till; Pingitore, Alessandro; Abolhassani, Nazanin; Medici, Marco; Kiemeney, Lambertus A L M; Riksen, Niels P; Dullaart, Robin P F; Trompet, Stella; Dörr, Marcus; Brown, Suzanne J; Schmidt, Börge; Führer-Sakel, Dagmar; Vanderpump, Mark P J; Muendlein, Axel; Drexel, Heinz; Fink, Howard A; ... (2023). The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis. The lancet. Diabetes & endocrinology, 11(10), pp. 743-754. Elsevier 10.1016/S2213-8587(23)00227-9
Young, William J; Lahrouchi, Najim; Isaacs, Aaron; Duong, ThuyVy; Foco, Luisa; Ahmed, Farah; Brody, Jennifer A; Salman, Reem; Noordam, Raymond; Benjamins, Jan-Walter; Haessler, Jeffrey; Lyytikäinen, Leo-Pekka; Repetto, Linda; Concas, Maria Pina; van den Berg, Marten E; Weiss, Stefan; Baldassari, Antoine R; Bartz, Traci M; Cook, James P; Evans, Daniel S; ... (2022). Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways. Nature communications, 13(1), p. 5144. Nature Publishing Group 10.1038/s41467-022-32821-z
Wang, Zhe; Emmerich, Andrew; Pillon, Nicolas J; Moore, Tim; Hemerich, Daiane; Cornelis, Marilyn C; Mazzaferro, Eugenia; Broos, Siacia; Ahluwalia, Tarunveer S; Bartz, Traci M; Bentley, Amy R; Bielak, Lawrence F; Chong, Mike; Chu, Audrey Y; Berry, Diane; Dorajoo, Rajkumar; Dueker, Nicole D; Kasbohm, Elisa; Feenstra, Bjarke; Feitosa, Mary F; ... (2022). Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention. Nature genetics, 54(9), pp. 1332-1344. Nature America 10.1038/s41588-022-01165-1
Castaneda, Andy B; Petty, Lauren E; Scholz, Markus; Jansen, Rick; Weiss, Stefan; Zhang, Xiaoling; Schramm, Katharina; Beutner, Frank; Kirsten, Holger; Schminke, Ulf; Hwang, Shih-Jen; Marzi, Carola; Dhana, Klodian; Seldenrijk, Adrie; Krohn, Knut; Homuth, Georg; Wolf, Petra; Peters, Marjolein J; Dörr, Marcus; Peters, Annette; ... (2022). Associations of carotid intima media thickness with gene expression in whole blood and genetically predicted gene expression across 48 tissues. Human molecular genetics, 31(7), pp. 1171-1182. Oxford University Press 10.1093/hmg/ddab236
Syrogiannouli, Lamprini; Wildisen, Lea; Meuwese, Christiaan; Bauer, Douglas C; Cappola, Anne R; Gussekloo, Jacobijn; den Elzen, Wendy P J; Trompet, Stella; Westendorp, Rudi G J; Jukema, J Wouter; Ferrucci, Luigi; Ceresini, Graziano; Åsvold, Bjørn O; Chaker, Layal; Peeters, Robin P; Imaizumi, Misa; Ohishi, Waka; Vaes, Bert; Völzke, Henry; Sgarbi, Josè A; ... (2022). Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies. Frontiers in psychiatry, 13, p. 774251. Frontiers 10.3389/fpsyt.2022.774251
van Vliet, Nicolien A; van Heemst, Diana; Almeida, Osvaldo P; Åsvold, Bjørn O; Aubert, Carole E.; Bae, Jong Bin; Barnes, Linda E; Bauer, Douglas C; Blauw, Gerard J; Brayne, Carol; Cappola, Anne R; Ceresini, Graziano; Comijs, Hannie C; Dartigues, Jean-Francois; Degryse, Jean-Marie; Dullaart, Robin P F; van Eersel, Marlise E A; den Elzen, Wendy P J; Ferrucci, Luigi; Fink, Howard A; ... (2021). Association of Thyroid Dysfunction With Cognitive Function: An Individual Participant Data Analysis. JAMA Internal Medicine, 181(11), pp. 1440-1450. American Medical Association 10.1001/jamainternmed.2021.5078
Wildisen, Lea; Del Giovane, Cinzia; Moutzouri, Elisavet; Beglinger, Shanthi; Syrogiannouli, Lamprini; Collet, Tinh-Hai; Cappola, Anne R; Åsvold, Bjørn O; Bakker, Stephan J L; Yeap, Bu B; Almeida, Osvaldo P; Ceresini, Graziano; Dullaart, Robin P F; Ferrucci, Luigi; Grabe, Hans; Jukema, J Wouter; Nauck, Matthias; Trompet, Stella; Völzke, Henry; Westendorp, Rudi; ... (2020). An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms. Scientific Reports, 10(1), p. 19111. Nature Publishing Group 10.1038/s41598-020-75776-1
Bahls, Martin; Lorenz, Matthias W; Dörr, Marcus; Gao, Lu; Kitagawa, Kazuo; Tuomainen, Tomi-Pekka; Agewall, Stefan; Berenson, Gerald; Catapano, Alberico L; Norata, Giuseppe D; Bots, Michiel L; van Gilst, Wiek; Asselbergs, Folkert W; Brouwers, Frank P; Uthoff, Heiko; Sander, Dirk; Poppert, Holger; Hecht Olsen, Michael; Empana, Jean Philippe; Schminke, Ulf; ... (2020). Progression of conventional cardiovascular risk factors and vascular disease risk in individuals: insights from the PROG-IMT consortium. European journal of preventive cardiology, 27(3), pp. 234-243. SAGE Publications 10.1177/2047487319877078
Schmidt, Amand F; Holmes, Michael V; Preiss, David; Swerdlow, Daniel I; Denaxas, Spiros; Fatemifar, Ghazaleh; Faraway, Rupert; Finan, Chris; Valentine, Dennis; Fairhurst-Hunter, Zammy; Hartwig, Fernando Pires; Horta, Bernardo Lessa; Hypponen, Elina; Power, Christine; Moldovan, Max; van Iperen, Erik; Hovingh, Kees; Demuth, Ilja; Norman, Kristina; Steinhagen-Thiessen, Elisabeth; ... (2019). Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. BMC cardiovascular disorders, 19(1), p. 240. BioMed Central 10.1186/s12872-019-1187-z
Wildisen, Lea; Moutzouri, Elisavet; Beglinger, Shanthi; Syrogiannouli, Lamprini; Cappola, Anne R; Åsvold, Bjørn O; Bakker, Stephan J L; Ceresini, Graziano; Dullaart, Robin; Ferrucci, Luigi; Grabe, Hans; Jukema, J Wouter; Nauck, Matthias; Trompet, Stella; Völzke, Henry; Westendorp, Rudi G J; Gussekloo, Jacobijn; Peeters, Robin P; Klöppel, Stefan; Aujesky, Drahomir; ... (2019). Subclinical thyroid dysfunction and depressive symptoms: protocol for a systematic review and individual participant data meta-analysis of prospective cohort studies. BMJ open, 9(7), e029716. BMJ Publishing Group 10.1136/bmjopen-2019-029716
Meuwese, Christiaan L; van Diepen, Merel; Cappola, Anne R; Sarnak, Mark J; Shlipak, Michael G; Bauer, Douglas C; Fried, Linda P; Iacoviello, Massimo; Vaes, Bert; Degryse, Jean; Khaw, Kay-Tee; Luben, Robert N; Åsvold, Bjørn O; Bjøro, Trine; Vatten, Lars J; de Craen, Anton J M; Trompet, Stella; Iervasi, Giorgio; Molinaro, Sabrina; Ceresini, Graziano; ... (2019). Low thyroid function is not associated with an accelerated deterioration in renal function. Nephrology, dialysis, transplantation, 34(4), pp. 650-659. Oxford University Press 10.1093/ndt/gfy071
Franceschini, Nora; Giambartolomei, Claudia; de Vries, Paul S; Finan, Chris; Bis, Joshua C; Huntley, Rachael P; Lovering, Ruth C; Tajuddin, Salman M; Winkler, Thomas W; Graff, Misa; Kavousi, Maryam; Dale, Caroline; Smith, Albert V; Hofer, Edith; van Leeuwen, Elisabeth M; Nolte, Ilja M; Lu, Lingyi; Scholz, Markus; Sargurupremraj, Muralidharan; Pitkänen, Niina; ... (2018). GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nature communications, 9(1), p. 5141. Nature Publishing Group 10.1038/s41467-018-07340-5
Wopereis, Daisy M; Du Puy, Robert S; van Heemst, Diana; Walsh, John P; Bremner, Alexandra; Bakker, Stephan J L; Bauer, Douglas C; Cappola, Anne R; Ceresini, Graziano; Degryse, Jean; Dullaart, Robin P F; Feller, Martin; Ferrucci, Luigi; Floriani, Carmen; Franco, Oscar H; Iacoviello, Massimo; Iervasi, Georgio; Imaizumi, Misa; Jukema, J Wouter; Khaw, Kay-Tee; ... (2018). The relation between thyroid function and anemia: a pooled analysis of individual participant data. Journal of clinical endocrinology and metabolism, 103(10), pp. 3658-3667. Endocrine Society 10.1210/jc.2018-00481
Baumgartner, Christine; Da Costa, Bruno R; Collet, Tinh-Hai; Feller, Martin; Floriani, Carmen; Bauer, Douglas C; Cappola, Anne R; Heckbert, Susan R; Ceresini, Graziano; Gussekloo, Jacobijn; den Elzen, Wendy P J; Peeters, Robin P; Luben, Robert; Völzke, Henry; Dörr, Marcus; Walsh, John P; Bremner, Alexandra; Iacoviello, Massimo; Macfarlane, Peter; Heeringa, Jan; ... (2017). Thyroid Function Within the Normal Range, Subclinical Hypothyroidism and the Risk of Atrial Fibrillation. Circulation, 136(22), pp. 2100-2116. Lippincott Williams & Wilkins 10.1161/CIRCULATIONAHA.117.028753
Hibar, Derrek P.; Hieab, H.H. Adams; Chauhan, Ganesh; Stein, Jason L.; Hofer, Edith; Renteria, Miguel E.; Bis, Joshua; Arias-Vasquez, Alejandro; Ikram, Kamran; Desrivières, Sylvane; Vernooij, Meike W.; Abramovic, Lucija; Alhusaini, Saud; Amin, Najaf; Andersson, Micael; Arfanakis, Konstantinos A.; Aribisala, Benjamin S.; Armstrong, Nicola J.; Athanasiu, Lavinia; Axelsson, Tomas; ... (2017). Novel genetic loci associated with hippocampal volume. Nature communications, 8, p. 13624. Nature Publishing Group 10.1038/ncomms13624
Chu, Audrey Y; Deng, Xuan; Fisher, Virginia A; Drong, Alexander; Zhang, Yang; Feitosa, Mary F; Liu, Ching-Ti; Weeks, Olivia; Choh, Audrey C; Duan, Qing; Dyer, Thomas D; Eicher, John D; Guo, Xiuqing; Heard-Costa, Nancy L; Kacprowski, Tim; Kent, Jack W; Lange, Leslie A; Liu, Xinggang; Lohman, Kurt; Lu, Lingyi; ... (2017). Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Nature genetics, 49(1), pp. 125-130. Nature America 10.1038/ng.3738
Cornelis, Marilyn C; Kacprowski, Tim; Menni, Cristina; Gustafsson, Stefan; Pivin, Edward; Adamski, Jerzy; Artati, Anna; Eap, Chin B; Ehret, Georg; Friedrich, Nele; Ganna, Andrea; Guessous, Idris; Homuth, Georg; Lind, Lars; Magnusson, Patrik K; Mangino, Massimo; Pedersen, Nancy L; Pietzner, Maik; Suhre, Karsten; Völzke, Henry; ... (2016). Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. Human molecular genetics, 25(24), pp. 5472-5482. Oxford University Press 10.1093/hmg/ddw334
Adams, Hieab H H; Hibar, Derrek P; Chouraki, Vincent; Stein, Jason L; Nyquist, Paul A; Rentería, Miguel E; Trompet, Stella; Arias-Vasquez, Alejandro; Seshadri, Sudha; Desrivières, Sylvane; Beecham, Ashley H; Jahanshad, Neda; Wittfeld, Katharina; Van der Lee, Sven J; Abramovic, Lucija; Alhusaini, Saud; Amin, Najaf; Andersson, Micael; Arfanakis, Konstantinos; Aribisala, Benjamin S; ... (2016). Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature neuroscience, 19(12), pp. 1569-1582. Nature America 10.1038/nn.4398
Chaker, Layal; Baumgartner, Christine; den Elzen, Wendy P J; Collet, Tinh-Hai; Ikram, M Arfan; Blum, Manuel; Dehghan, Abbas; Drechsler, Christiane; Luben, Robert N; Portegies, Marileen L P; Iervasi, Giorgio; Medici, Marco; Stott, David J; Dullaart, Robin P; Ford, Ian; Bremner, Alexandra; Newman, Anne B; Wanner, Christoph; Sgarbi, José A; Dörr, Marcus; ... (2016). Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis. The Journal of clinical endocrinology and metabolism, 101(11), pp. 4270-4282. The Endocrine Society 10.1210/jc.2016-2255
Andlauer, Till F M; Buck, Dorothea; Antony, Gisela; Bayas, Antonios; Bechmann, Lukas; Berthele, Achim; Chan, Andrew; Gasperi, Christiane; Gold, Ralf; Graetz, Christiane; Haas, Jürgen; Hecker, Michael; Infante-Duarte, Carmen; Knop, Matthias; Kümpfel, Tania; Limmroth, Volker; Linker, Ralf A; Loleit, Verena; Luessi, Felix; Meuth, Sven G; ... (2016). Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. Science Advances, 2(6), e1501678. American Association for the Advancement of Science 10.1126/sciadv.1501678
Pattaro, Cristian; Teumer, Alexander; Gorski, Mathias; Chu, Audrey Y; Li, Man; Mijatovic, Vladan; Garnaas, Maija; Tin, Adrienne; Sorice, Rossella; Li, Yong; Taliun, Daniel; Olden, Matthias; Foster, Meredith; Yang, Qiong; Chen, Ming-Huei; Pers, Tune H; Johnson, Andrew D; Ko, Yi-An; Fuchsberger, Christian; Tayo, Bamidele; ... (2016). Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature communications, 7, p. 10023. Nature Publishing Group 10.1038/ncomms10023
Teumer, Alexander; Tin, Adrienne; Sorice, Rossella; Gorski, Mathias; Yeo, Nan Cher; Chu, Audrey Y; Li, Man; Li, Yong; Mijatovic, Vladan; Ko, Yi-An; Taliun, Daniel; Luciani, Alessandro; Chen, Ming-Huei; Yang, Qiong; Foster, Meredith C; Olden, Matthias; Hiraki, Linda T; Tayo, Bamidele O; Fuchsberger, Christian; Dieffenbach, Aida Karina; ... (2015). Genome-wide Association Studies Identify Genetic Loci Associated with Albuminuria in Diabetes. Diabetes, 65(3), pp. 803-817. American Diabetes Association 10.2337/db15-1313
Buch, Stephan; Stickel, Felix; Trépo, Eric; Way, Michael; Herrmann, Alexander; Nischalke, Hans Dieter; Brosch, Mario; Rosendahl, Jonas; Berg, Thomas; Ridinger, Monika; Rietschel, Marcella; McQuillin, Andrew; Frank, Josef; Kiefer, Falk; Schreiber, Stefan; Lieb, Wolfgang; Soyka, Michael; Semmo, Nasser; Aigner, Elmar; Datz, Christian; ... (2015). A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis. Nature genetics, 47(12), pp. 1443-1448. Nature America 10.1038/ng.3417
Åsvold, Bjørn O; Vatten, Lars J; Bjøro, Trine; Bauer, Douglas C; Bremner, Alexandra; Cappola, Anne R; Ceresini, Graziano; den Elzen, Wendy P J; Ferrucci, Luigi; Franco, Oscar H; Franklyn, Jayne A; Gussekloo, Jacobijn; Iervasi, Giorgio; Imaizumi, Misa; Kearney, Patricia M; Khaw, Kay-Tee; Maciel, Rui M B; Newman, Anne B; Peeters, Robin P; Psaty, Bruce M; ... (2015). Thyroid function within the normal range and risk of coronary heart disease: an individual participant data analysis of 14 cohorts. JAMA Internal Medicine, 175(6), pp. 1037-1047. American Medical Association 10.1001/jamainternmed.2015.0930
Chaker, Layal; Baumgartner, Christine; den Elzen, Wendy P J; Ikram, M Arfan; Blum, Manuel; Collet, Tinh-Hai; Bakker, Stephan J L; Dehghan, Abbas; Drechsler, Christiane; Luben, Robert N; Hofman, Albert; Portegies, Marileen L P; Medici, Marco; Iervasi, Giorgio; Stott, David J; Ford, Ian; Bremner, Alexandra; Wanner, Christoph; Ferrucci, Luigi; Newman, Anne B; ... (2015). Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis. Journal of clinical endocrinology and metabolism, 100(6), pp. 2181-2191. Endocrine Society 10.1210/jc.2015-1438
Collet, Tinh-Hai; Bauer, Douglas C; Cappola, Anne R; Asvold, Bjørn O; Weiler, Stefan; Vittinghoff, Eric; Gussekloo, Jacobijn; Bremner, Alexandra; den Elzen, Wendy P J; Maciel, Rui M B; Vanderpump, Mark P J; Cornuz, Jacques; Dörr, Marcus; Wallaschofski, Henri; Newman, Anne B; Sgarbi, José A; Razvi, Salman; Völzke, Henry; Walsh, John P; Aujesky, Drahomir; ... (2014). Thyroid antibody status, subclinical hypothyroidism, and the risk of coronary heart disease: an individual participant data analysis. The Journal of clinical endocrinology and metabolism, 99(9), pp. 3353-3362. The Endocrine Society 10.1210/jc.2014-1250
Lubitz, Steven A; Lunetta, Kathryn L; Lin, Honghuang; Arking, Dan E; Trompet, Stella; Li, Guo; Krijthe, Bouwe P; Chasman, Daniel I; Barnard, John; Kleber, Marcus E; Dörr, Marcus; Ozaki, Kouichi; Smith, Albert V; Müller-Nurasyid, Martina; Walter, Stefan; Agarwal, Sunil K; Bis, Joshua C; Brody, Jennifer A; Chen, Lin Y; Everett, Brendan M; ... (2014). Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. Journal of the American College of Cardiology, 63(12), pp. 1200-1210. Elsevier 10.1016/j.jacc.2013.12.015
Fuhs, Andrea; Bentama, Dunya; Hoffmann, Wolfgang; Völzke, Henry; Mathis, Johannes; Kraywinkel, Klaus; Berger, Klaus (2014). Restless legs syndrome and cancer: an analysis in three independent studies. Epidemiology Reports, 2(1), p. 4. Herbert Publications 10.7243/2054-9911-2-4
Stickel, Felix; Buch, Stephan; Zoller, Heinz; Hultcrantz, Rolf; Gallati, Sabina; Österreicher, Christoph; Finkenstedt, Armin; Stadlmayr, Andreas; Aigner, Elmar; Sahinbegovic, Enijad; Sarrazin, Christoph; Schafmayer, Clemens; Braun, Felix; Erhart, Wiebke; Nothnagel, Michael; Lerch, Markus M; Mayerle, Julia; Völzke, Henry; Schaller, André; Kratzer, Wolfgang; ... (2014). Evaluation of genome-wide loci of iron metabolism in hereditary hemochromatosis identifies PCSK7 as a host risk factor of liver cirrhosis. Human molecular genetics, 23(14), pp. 3883-3890. Oxford University Press 10.1093/hmg/ddu076
Collet, Tinh-Hai; Gussekloo, Jacobijn; Bauer, Douglas C; den Elzen, Wendy P J; Cappola, Anne R; Balmer, Philippe; Iervasi, Giorgio; Åsvold, Bjørn O; Sgarbi, José A; Völzke, Henry; Gencer, Bariş; Maciel, Rui M B; Molinaro, Sabrina; Bremner, Alexandra; Luben, Robert N; Maisonneuve, Patrick; Cornuz, Jacques; Newman, Anne B; Khaw, Kay-Tee; Westendorp, Rudi G J; ... (2012). Subclinical hyperthyroidism and the risk of coronary heart disease and mortality. Archives of internal medicine, 172(10), pp. 799-809. Chicago, Ill.: American Medical Association 10.1001/archinternmed.2012.402
Stickel, Felix; Buch, Stephan; Lau, Katharina; Meyer zu Schwabedissen, Henriette; Berg, Thomas; Ridinger, Monika; Rietschel, Marcella; Schafmayer, Clemens; Braun, Felix; Hinrichsen, Holger; Günther, Rainer; Arlt, Alexander; Seeger, Marcus; Müller, Sebastian; Seitz, Helmut Karl; Soyka, Michael; Lerch, Markus; Lammert, Frank; Sarrazin, Christoph; Kubitz, Ralf; ... (2011). Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians. Hepatology, 53(1), pp. 86-95. Hoboken, N.J.: Wiley Interscience 10.1002/hep.24017
