Hediger, Matthias; Hepworth, D (eds.) (2016). Membrane Transporters: Solute Carriers, 7. Royal Society of Chemistry
Metabolic homeostasis within cells requires strict control over the import and export of metabolites, nutrients and ions across membranes. Polar chemical species such as these have negligible ability to cross phospholipid membranes by simple diffusion and instead require highly regulated transport proteins to control their movement. The largest class of transport proteins is the solute carrier (SLC) series (www.bioparadigms.org) and it is on this superfamily that this themed collection focuses.
These proteins are of great interest for basic academic research, but beyond that they are of central importance in a number of areas of applied science: as drug targets, as controllers of drug disposition and pharmacokinetics, and as the cause of drug toxicity.
This collection of articles, guest edited by Prof Matthias A. Hediger (University of Bern, Switzerland ) and & Dr David Hepworth (Pfizer) is a celebration of all areas of research where the chemical sciences have impacted the study of the SLC superfamily.
Item Type: |
Journal or Series ((Book) Series) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Biochemistry and Molecular Medicine |
UniBE Contributor: |
Hediger, Matthias |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
Publisher: |
Royal Society of Chemistry |
Language: |
English |
Submitter: |
Kevin Marc Rupp |
Date Deposited: |
05 Jun 2018 10:39 |
Last Modified: |
05 Dec 2022 15:10 |
URI: |
https://boris.unibe.ch/id/eprint/110865 |
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