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Maccarrone, Mauro; Di Marzo, Vincenzo; Gertsch, Juerg; Grether, Uwe; Howlett, Allyn C; Hua, Tian; Makriyannis, Alexandros; Piomelli, Daniele; Ueda, Natsuo; van der Stelt, Mario (2023). Goods and bads of endocannabinoid system as a therapeutic target: Lessons learned after 30 years. Pharmacological reviews, 75(5), pp. 885-958. American Society for Pharmacology and Experimental Therapeutics 10.1124/pharmrev.122.000600

Krishnan, Sandhya R; Skiba, Adrianna; Luca, Simon Vlad; Marcourt, Laurence; Wolfender, Jean-Luc; Skalicka-Woźniak, Krystyna; Gertsch, Jürg (2023). Bioactivity-guided isolation of trypanocidal coumarins and dihydro-pyranochromones from selected Apiaceae plant species. Phytochemistry, 213, p. 113770. Elsevier 10.1016/j.phytochem.2023.113770

Gertsch, Jürg; Heilmann, Jörg; Skaltsa, Eleni (2023). Editorial. Phytochemistry, 213(113781), p. 113781. Elsevier 10.1016/j.phytochem.2023.113781

Selimi, Zoja; Rougier, Jean-Sébastien; Abriel, Hugues; Kucera, Jan P (2023). A detailed analysis of single-channel Nav 1.5 recordings does not reveal any cooperative gating. The journal of physiology, 601(17), pp. 3847-3868. The Physiological Society 10.1113/JP284861

Thompson, Danielle; Cismaru, Christiana Victoria; Rougier, Jean-Sébastien; Schwemmle, Martin; Zimmer, Gert (2023). The M2 proteins of bat influenza A viruses reveal atypical features compared to conventional M2 proteins. Journal of virology, 97(8), e0038823. American Society for Microbiology 10.1128/jvi.00388-23

Fischer, Jérôme Paul; Bátora, Dániel; Dick, Luca Julian; Kaderli, Reto Martin; Gertsch, Jürg; Lochner, Martin (8 August 2023). Developing Molecular Tools for the Study and Detection of Calcium-Sensing Receptor [MC-112]. CHIMIA, 77(7/8), p. 526. Schweizerische Chemische Gesellschaft

Gerber, Christian Elias; Grossenbacher, Philipp; Singer, Simon Alex; Lochner, Martin (8 August 2023). Development of novel 4-chloro-2-(2-phenoxyacetamido)benzoic acid-based TRPM4 inhibitors [MC-115]. CHIMIA, 77(7/8), p. 526. Schweizerische Chemische Gesellschaft

Papapostolou, Irida; Ross, Daniela; Bochen, Florian; Peinelt, Christine; Maldifassi, Maria Constanza (2023). Contribution of the α5 nAChR Subunit and α5SNP to Nicotine-Induced Proliferation and Migration of Human Cancer Cells. Cells, 12(15) MDPI 10.3390/cells12152000

Khaddaj, Rasha; Kukulski, Wanda (2023). Piecing together the structural organisation of lipid exchange at membrane contact sites. Current opinion in cell biology, 83, p. 102212. Elsevier 10.1016/j.ceb.2023.102212

Arullampalam, Prakash; Essers, Maria C; Boukenna, Mey; Guichard, Sabrina; Rougier, Jean-Sébastien; Abriel, Hugues (2023). Knockdown of the TRPM4 channel alters cardiac electrophysiology and hemodynamics in a sex- and age-dependent manner in mice. Physiological reports, 11(16) The American Physiological Society 10.14814/phy2.15783

Iamshanova, Oksana; Rougier, Jean-Sébastien; Abriel, Hugues (2023). Exploring the Oligomerization of Nav1.5 and Its Implication for the Dominant-Negative Effect. Bioelectricity, 5 Mary Ann Liebert 10.1089/bioe.2023.0014

Skiba, Adrianna; Pellegata, Daniele; Morozova, Veronika; Kozioł, Ewelina; Budzyńska, Barbara; Lee, Simon Ming-Yuen; Gertsch, Jürg; Skalicka-Woźniak, Krystyna (2023). Pharmacometabolic Effects of Pteryxin and Valproate on Pentylenetetrazole-Induced Seizures in Zebrafish Reveal Vagus Nerve Stimulation. Cells, 12(11) MDPI 10.3390/cells12111540

Maldifassi, Maria Constanza; Campello, Hugo Rego; Gallagher, Timothy; Lester, Henry A; Dougherty, Dennis A (2023). Human α6β4 nicotinic acetylcholine receptor: heterologous expression and agonist behavior provide insights into the immediate binding site. Molecular pharmacology, 103(6), pp. 339-347. American Society for Pharmacology and Experimental Therapeutics 10.1124/molpharm.123.000672

Wozny, Michael R; Di Luca, Andrea; Morado, Dustin R; Picco, Andrea; Khaddaj, Rasha; Campomanes, Pablo; Ivanović, Lazar; Hoffmann, Patrick C; Miller, Elizabeth A; Vanni, Stefano; Kukulski, Wanda (2023). In situ architecture of the ER-mitochondria encounter structure. Nature, 618(7963), pp. 188-192. Macmillan Journals Ltd. 10.1038/s41586-023-06050-3

Ontsouka, Edgar; Schroeder, Mariana; Ok, Linda; Vaillancourt, Cathy; Stroka, Deborah; Albrecht, Christiane (2023). The Placenta-A New Source of Bile Acids during Healthy Pregnancy? First Results of a Gene Expression Study in Humans and Mice. International journal of molecular sciences, 24(11) MDPI 10.3390/ijms24119511

Kara, Nilufer; Ayoub, Nooraldeen; Ilgu, Huseyin; Fotiadis, Dimitrios; Ilgu, Muslum (2023). Aptamers Targeting Membrane Proteins for Sensor and Diagnostic Applications. Molecules, 28(9) Molecular Diversity Preservation International MDPI 10.3390/molecules28093728

Boukenna, Mey; Rougier, Jean-Sébastien; Aghagolzadeh, Parisa; Pradervand, Sylvain; Guichard, Sabrina; Hämmerli, Anne-Flore; Pedrazzini, Thierry; Abriel, Hugues (2023). Multiomics uncover the pro-inflammatory role of Trpm4 deletion after myocardial infarction in mice. American journal of physiology - heart and circulatory physiology, 324(4), H504-H518. American Physiological Society 10.1152/ajpheart.00671.2022

Ayoub, Nooraldeen; Roth, Patrick; Ucurum, Zöhre; Fotiadis, Dimitrios; Hirschi, Stephan (2023). Structural and biochemical insights into His-tag-induced higher-order oligomerization of membrane proteins by cryo-EM and size exclusion chromatography. Journal of structural biology, 215(1), p. 107924. Elsevier 10.1016/j.jsb.2022.107924

Ganeva, Iva; Lim, Koini; Boulanger, Jerome; Hoffmann, Patrick C; Muriel, Olivia; Borgeaud, Alicia C; Hagen, Wim J H; Savage, David B; Kukulski, Wanda (2023). The architecture of Cidec-mediated interfaces between lipid droplets. (In Press). Cell reports, 42(2), p. 112107. Cell Press 10.1016/j.celrep.2023.112107

Selimi, Zoja; Rougier, Jean-Sébastien; Abriel, Hugues; Kucera, Jan P (2023). No evidence of functional interactions between cardiac sodium channels. Biophysical journal, 122(3 S1), 101a-102a. Elsevier 10.1016/j.bpj.2022.11.736

Kalbermatter, David; Jeckelmann, Jean-Marc; Wyss, Marianne; Shrestha, Neeta; Pliatsika, Dimanthi; Riedl, Rainer; Lemmin, Thomas; Plattet, Philippe; Fotiadis, Dimitrios (2023). Structure and supramolecular organization of the canine distemper virus attachment glycoprotein. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 120(6), e2208866120. National Academy of Sciences NAS 10.1073/pnas.2208866120

Kolatt Chandran, Sailendrakumar; Yiannakas, Adonis; Kayyal, Haneen; Salalha, Randa; Cruciani, Federica; Mizrahi, Liron; Khamaisy, Mohammad; Stern, Shani; Rosenblum, Kobi (2023). Intrinsic excitability in layer IV-VI anterior insula to basolateral amygdala projection neurons correlates with the confidence of taste valence encoding. eNeuro, 10(1) Society for Neuroscience 10.1523/ENEURO.0302-22.2022

Reynoso-Moreno, Ines; Rau, Mark; Chicca, Andrea; Nicolussi, Simon; Gertsch, Jürg (2023). Assay of Endocannabinoid Uptake. Methods in molecular biology, 2576, pp. 329-348. Springer 10.1007/978-1-0716-2728-0_28

Kantipudi, Satish; Harder, Daniel; Fotiadis, Dimitrios (2023). Characterization of substrates and inhibitors of the human heterodimeric transporter 4F2hc-LAT1 using purified protein and the scintillation proximity radioligand binding assay. Frontiers in physiology, 14(1148055), p. 1148055. Frontiers Research Foundation 10.3389/fphys.2023.1148055

Ontsouka, Edgar; Schröder, Mariana; Albrecht, Christiane (2023). Revisited role of the placenta in bile acid homeostasis. Frontiers in physiology, 14(1213757), p. 1213757. Frontiers Research Foundation 10.3389/fphys.2023.1213757


Preti, Barbara; Rougier, Jean-Sébastien; Papapostolou, Irida; Bochen, Florian; Gerber, Christian E; Abriel, Hugues; Lochner, Martin; Peinelt, Christine (2022). Targeting Ion Channel TRPM4. CHIMIA, 76(12), pp. 1039-1044. Schweizerische Chemische Gesellschaft 10.2533/chimia.2022.1039

Zaugg, Jonas; Pujol Giménez, Jonai; Cabra, Romina Silvia; Hofstetter, Wilhelm; Hediger, Matthias; Albrecht, Christiane (2022). New Insights into the Physiology of Iron Transport: An Interdisciplinary Approach. CHIMIA, 76(12), pp. 996-1004. 10.2533/chimia.2022.996

Hill, Emily; Huang, Xianglin; Del Popolo, Ivana; La Mache, Circe; Lochner, Martin; Ladds, Graham; Frenguelli, Bruno G.; Wall, Mark J. (2 December 2022). Species-dependent actions of the Goαb selective adenosine A1 receptor agonist BnOCPA (bioRxiv). Cold Spring Harbor Laboratory 10.1101/2022.12.02.518704

Preti, Barbara; Suchankova, Anna; Deganutti, Giuseppe; Leuenberger, Michele; Barkan, Kerry; Manulak, Iga; Huang, Xianglin; Carvalho, Sabrina; Ladds, Graham; Lochner, Martin (2022). Discovery and Structure-Activity Relationship Studies of Novel Adenosine A1 Receptor-Selective Agonists. Journal of medicinal chemistry, 65(21), pp. 14864-14890. American Chemical Society 10.1021/acs.jmedchem.2c01414

Hirschi, Stephan; Ward, Thomas R; Meier, Wolfgang P; Müller, Daniel J; Fotiadis, Dimitrios (2022). Synthetic Biology: Bottom-Up Assembly of Molecular Systems. Chemical reviews, 122(21), pp. 16294-16328. American Chemical Society 10.1021/acs.chemrev.2c00339

Melero, Alejandro; Boulanger, Jerome; Kukulski, Wanda; Miller, Elizabeth A (2022). Ultrastructure of COPII vesicle formation in yeast characterised by correlative light and electron microscopy. Molecular biology of the cell, 33(13), ar122. American Society for Cell Biology 10.1091/mbc.E22-03-0103

Jeckelmann, Jean-Marc; Lemmin, Thomas; Schlapschy, Martin; Skerra, Arne; Fotiadis, Dimitrios (2022). Structure of the human heterodimeric transporter 4F2hc-LAT2 in complex with Anticalin, an alternative binding protein for applications in single-particle cryo-EM. Scientific reports, 12(1), p. 18269. Springer Nature 10.1038/s41598-022-23270-1

Grossenbacher, Philipp; Essers, Maria C; Moser, Joël; Singer, Simon A; Häusler, Stephanie; Stieger, Bruno; Rougier, Jean-Sébastien; Lochner, Martin (2022). Bioorthogonal site-selective conjugation of fluorescent dyes to antibodies: method and potential applications. RSC advances, 12(44), pp. 28306-28317. Royal Society of Chemistry 10.1039/d2ra05580e

Abou Hamdan, Abbas; Mahler, Roman; Grossenbacher, Philipp; Biner, Olivier; Sjöstrand, Dan; Lochner, Martin; Högbom, Martin; von Ballmoos, Christoph (2022). Functional design of bacterial superoxide:quinone oxidoreductase. Biochimica et biophysica acta. Bioenergetics, 1863(7), p. 148583. Elsevier 10.1016/j.bbabio.2022.148583

Kappel, Sven; Peinelt, Christine (2022). Targeting CRAC channels in inflammatory bowel disease. EMBO molecular medicine, 14(9), e16489. EMBO Press 10.15252/emmm.202216489

Graff, Julien; Müller, Jennifer; Sadurní, Anna; Rubin, Matthias; Cuissa, Inês André Canivete; Keller, Claudia; Hartmann, Marco; Singer, Simon; Gertsch, Jürg; Altmann, Karl-Heinz (2022). The Evaluation of L-Tryptophan Derivatives as Inhibitors of the LType Amino Acid Transporter LAT1 (SLC7A5). ChemMedChem, 17(17), e202200308. Wiley-VCH 10.1002/cmdc.202200308

Ruggeri, Francesca; Schwemmer, Christian; Stauffer, Mirko; Nicollier, Philippe; Figueiredo da Silva, Jacqueline; Bosshart, Patrick D; Kochems, Kirstin; Fotiadis, Dimitrios; Knoll, Armin; Wolf, Heiko (2022). Placement of Biological Membrane Patches in a Nanofluidic Gap With Control Over Position and Orientation. Advanced materials interfaces, 9(23), p. 2200941. Wiley 10.1002/admi.202200941

Vachalova, Veronika; Karahoda, Rona; Ottaviani, Martina; Anandam, Kasin Yadunandam; Abad, Cilia; Albrecht, Christiane; Staud, Frantisek (2022). Functional reorganization of monoamine transport systems during villous trophoblast differentiation: evidence of distinct differences between primary human trophoblasts and BeWo cells. Reproductive biology and endocrinology, 20(1), p. 112. BioMed Central 10.1186/s12958-022-00981-8

Zaugg, Jonas; Solenthaler, Fabia Sina; Albrecht, Christiane (2022). Materno-fetal iron transfer and the emerging role of ferroptosis pathways. Biochemical pharmacology, 202, p. 115141. Elsevier 10.1016/j.bcp.2022.115141

Schneider, Henning; Albrecht, Christiane; Ahmed, Mahmoud S; Broekhuizen, Michelle; Aengenheister, Leonie; Buerki-Thurnherr, Tina; Danser, A H Jan; Gil, Sophie; Hansson, Stefan R; Greupink, Rick; Lewis, Rohan M; Markert, Udo R; Mathiesen, Line; Powles-Glover, Nicola; Wadsack, Christian; Brownbill, Paul (2022). Ex vivo dual perfusion of an isolated human placenta cotyledon: Towards protocol standardization and improved inter-centre comparability. Placenta, 126, pp. 83-89. Elsevier 10.1016/j.placenta.2022.05.003

Wall, Mark J; Hill, Emily; Huckstepp, Robert; Barkan, Kerry; Deganutti, Giuseppe; Leuenberger, Michele; Preti, Barbara; Winfield, Ian; Carvalho, Sabrina; Suchankova, Anna; Wei, Haifeng; Safitri, Dewi; Huang, Xianglin; Imlach, Wendy; La Mache, Circe; Dean, Eve; Hume, Cherise; Hayward, Stephanie; Oliver, Jess; Zhao, Fei-Yue; ... (2022). Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression. Nature communications, 13(1), p. 4150. Nature Publishing Group 10.1038/s41467-022-31652-2

Augustynek, Bartlomiej; Gyimesi, Gergely; Dernič, Jan; Sallinger, Matthias; Albano, Giuseppe; Klesse, Gabriel J; Kandasamy, Palanivel; Grabmayr, Herwig; Frischauf, Irene; Fuster, Daniel G; Peinelt, Christine; Hediger, Matthias A; Bhardwaj, Rajesh (2022). Discovery of novel gating checkpoints in the Orai1 calcium channel by systematic analysis of constitutively active mutants of its paralogs and orthologs. Cell calcium, 105, p. 102616. Elsevier 10.1016/j.ceca.2022.102616

Fischer, Jérôme; Batora, Daniel; Kaderli, Reto Martin; Gertsch, Jürg; Lochner, Martin (July 2022). Developing Molecular Tools for the Study and Detection of Calcium-Sensing Receptor (CaSR) in Parathyroid Glands [MC-112]. CHIMIA, 76(7/8), p. 693. Schweizerische Chemische Gesellschaft

Grossenbacher, Philipp; Lochner, Martin (July 2022). Rapid Synthesis of Trifunctionalised Chemical Biology Probe from Unprotected L-Cysteine [MC-115]. CHIMIA, 76(7/8), p. 693. Schweizerische Chemische Gesellschaft

Fuenzalida, Barbara; Kallol, Sampada; Zaugg, Jonas; Müller, Martin; Mistry, Hiten D; Gutierrez, Jaime; Leiva, Andrea; Albrecht, Christiane (2022). Primary Human Trophoblasts Mimic the Preeclampsia Phenotype after Acute Hypoxia-Reoxygenation Insult. Cells, 11(12) MDPI 10.3390/cells11121898

Mistry, Hiten D; Klossner, Rahel; Kallol, Sampada; Lüthi, Michael P; Moser, Ruedi; Schneider, Henning; Ontsouka, Edgar C; Kurlak, Lesia O; Mohaupt, Markus G.; Albrecht, Christiane (2022). Effects of aldosterone on the human placenta: Insights from placental perfusion studies. Placenta, 123, pp. 32-40. Elsevier 10.1016/j.placenta.2022.03.129

Dokshokova, Lolita; Franzoso, Mauro; Bona, Anna Di; Moro, Nicola; Sanchez-Alonso-Mardones, Josè; Prando, Valentina; Sandre, Michele; Basso, Cristina; Faggian, Giuseppe; Abriel, Hugues; Marin, Oriano; Gorelik, Julia; Zaglia, Tania; Mongillo, Marco (2022). Nerve Growth Factor transfer from cardiomyocytes to innervating sympathetic neurons activates TrkA receptors at the neuro-cardiac junction. The journal of physiology, 600(12), pp. 2853-2875. The Physiological Society 10.1113/JP282828

Kappel, Sven; Ross, Daniela; Hauert, Barbara; Rother, Karen; Peinelt, Christine (2022). p53 alters intracellular Ca2+ signaling through regulation of TRPM4. Cell calcium, 104(102591), p. 102591. Elsevier 10.1016/j.ceca.2022.102591

Stokłosa, Paulina; Kappel, Sven; Peinelt, Christine (2022). A Novel Role of the TRPM4 Ion Channel in Exocytosis. Cells, 11(11) MDPI 10.3390/cells11111793

Bononi, Giulia; Di Stefano, Miriana; Poli, Giulio; Ortore, Gabriella; Meier, Philip; Masetto, Francesca; Caligiuri, Isabella; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Avan, Amir; Giovannetti, Elisa; Vagaggini, Chiara; Brai, Annalaura; Dreassi, Elena; Valoti, Massimo; Minutolo, Filippo; Granchi, Carlotta; Gertsch, Jürg and Tuccinardi, Tiziano (2022). Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives. Journal of medicinal chemistry, 65(10), pp. 7118-7140. American Chemical Society 10.1021/acs.jmedchem.1c01806

Gazzi, Thais; Brennecke, Benjamin; Atz, Kenneth; Korn, Claudia; Sykes, David; Forn-Cuni, Gabriel; Pfaff, Patrick; Sarott, Roman C; Westphal, Matthias V; Mostinski, Yelena; Mach, Leonard; Wasinska-Kalwa, Malgorzata; Weise, Marie; Hoare, Bradley L; Miljuš, Tamara; Mexi, Maira; Roth, Nicolas; Koers, Eline J; Guba, Wolfgang; Alker, André; ... (2022). Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe. Chemical Science, 13(19), pp. 5539-5545. The Royal Society of Chemistry 10.1039/d1sc06659e

Iyer, Advaitha Subramanyam; Niemann, Moritz; Serricchio, Mauro; Dewar, Caroline E; Oeljeklaus, Silke; Farine, Luce; Warscheid, Bettina; Schneider, André; Bütikofer, Peter (2022). The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei. PLoS pathogens, 18(5), e1009717. Public Library of Science 10.1371/journal.ppat.1009717

Hinden, Liad; Ahmad, Majdoleen; Hamad, Sharleen; Nemirovski, Alina; Szanda, Gergő; Glasmacher, Sandra; Kogot-Levin, Aviram; Abramovitch, Rinat; Thorens, Bernard; Gertsch, Jürg; Leibowitz, Gil; Tam, Joseph (2022). Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function. Nature Communications, 13(1), p. 1783. Springer Nature 10.1038/s41467-022-29124-8

Knüsel, Sebastian; Jenni, Aurelio; Benninger, Mattias; Bütikofer, Peter; Roditi, Isabel (2022). Persistence of Trypanosoma brucei as early procyclic forms and social motility are dependent on glycosylphosphatidylinositol transamidase. Molecular microbiology, 117(4), pp. 802-817. Wiley 10.1111/mmi.14873

Espinoza, Cristian; Fuenzalida, Barbara; Leiva, Andrea (2022). Epigenetic Changes as a Possible Mechanism Leading to Increased Fetal Cardiovascular Disease Risk in Pregnancies with Gestational Diabetes Mellitus and/or Maternal Hypercholesterolemia. Current vascular pharmacology, 20(4), p. 381. Bentham Science 10.2174/1570161120666220314090700

Farfariello, Valerio; Gordienko, Dmitri V; Mesilmany, Lina; Touil, Yasmine; Germain, Emmanuelle; Fliniaux, Ingrid; Desruelles, Emilie; Gkika, Dimitra; Roudbaraki, Morad; Shapovalov, George; Noyer, Lucile; Lebas, Mathilde; Allart, Laurent; Zienthal-Gelus, Nathalie; Iamshanova, Oksana; Bonardi, Franck; Figeac, Martin; Laine, William; Kluza, Jerome; Marchetti, Philippe; ... (2022). TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence. Nature Communications, 13(1), p. 956. Springer Nature 10.1038/s41467-022-28597-x

Lüscher, Benjamin P.; Albrecht, Christiane; Stieger, Bruno; Surbek, Daniel V.; Baumann, Marc U. (2022). Glucose Transporter 9 (GLUT9) Plays an Important Role in the Placental Uric Acid Transport System. Cells, 11(4) MDPI 10.3390/cells11040633

Cowton, Andrew; Bütikofer, Peter; Häner, Robert; Menon, Anant K (2022). Identification of TbPBN1 in Trypanosoma brucei reveals a conserved heterodimeric architecture for glycosylphosphatidylinositol-mannosyltransferase I. Molecular microbiology, 117(2), pp. 450-461. Wiley 10.1111/mmi.14859

Kowalczyk, Joanna; Budzyńska, Barbara; Kurach, Łukasz; Pellegata, Daniele; El Sayed, Nesrine S; Gertsch, Jürg; Skalicka-Woźniak, Krystyna (2022). Neuropsychopharmacological profiling of scoparone in mice. Scientific reports, 12(1), p. 822. Springer Nature 10.1038/s41598-021-04741-3

Andrieu, Thomas; Chicca, Andrea; Pellegata, Daniele; Bersinger, Nick A.; Imboden, Sara; Nirgianakis, Konstantinos; Gertsch, Jürg; Mueller, Michael D. (2022). Association of endocannabinoids with pain in endometriosis. Pain, 163(1), pp. 193-203. Elsevier 10.1097/j.pain.0000000000002333

Karahoda, Rona; Zaugg, Jonas; Fuenzalida, Barbara; Kallol, Sampada; Moser-Haessig, Ruedi; Staud, Frantisek; Albrecht, Christiane (2022). Trophoblast Differentiation Affects Crucial Nutritive Functions of Placental Membrane Transporters. Frontiers in cell and developmental biology, 10, p. 820286. Frontiers 10.3389/fcell.2022.820286

Loffreda, Alessio; Schlame, Michael; Bütikofer, Peter (2022). StaR-related lipid transfer-like domain-containing protein CLDP43 affects cardiolipin synthesis and mitochondrial function in Trypanosoma brucei. PLoS ONE, 17(4), e0259752. Public Library of Science 10.1371/journal.pone.0259752

Schroeder, Mariana; Badini, Gina; Sferruzzi-Perri, Amanda N; Albrecht, Christiane (2022). The Consequences of Assisted Reproduction Technologies on the Offspring Health Throughout Life: A Placental Contribution. Frontiers in cell and developmental biology, 10, p. 906240. Frontiers 10.3389/fcell.2022.906240

Stauffer, Mirko; Jeckelmann, Jean-Marc; Ilgü, Hüseyin; Ucurum, Zöhre; Boggavarapu, Rajendra; Fotiadis, Dimitrios (2022). Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor. Communications chemistry, 5(1) Springer Nature 10.1038/s42004-022-00636-0


Shrestha, Neeta; Gall, Flavio Max; Mathieu, Cyrille; Hierweger, Melanie Michaela; Brügger, Melanie; Alves, Marco P.; Vesin, Jonathan; Banfi, Damiano; Kalbermatter, David; Horvat, Branka; Chambon, Marc; Turcatti, Gerardo; Fotiadis, Dimitrios; Riedl, Rainer; Plattet, Philippe (2021). Highly Potent Host-Specific Small-Molecule Inhibitor of Paramyxovirus and Pneumovirus Replication with High Resistance Barrier. mBio, 12(6), e0262121. American Society for Microbiology 10.1128/mBio.02621-21

Li, Jin (2021). The Role of Autoantibodies in Arrhythmogenesis. Current cardiology reports, 23(1), p. 3. Springer 10.1007/s11886-020-01430-x

Serricchio, Mauro; Bütikofer, Peter (2021). A Conserved Mitochondrial Chaperone-Protease Complex Involved in Protein Homeostasis. Frontiers in Molecular Biosciences, 8, p. 767088. Frontiers 10.3389/fmolb.2021.767088

Gertsch, Jürg (2021). Travelogues from the Rainforest: Notes on Prof. Otto Sticher's 85th birthday. Planta medica, 87(14), pp. 1123-1127. Thieme 10.1055/a-1508-0613

Shahnawaz, Saira; Nawaz, Usman Shah; Zaugg, Jonas; Hussain, Ghulam; Malik, Nadia; Dogar, Muhammad Zahoor-Ul-Hassan; Malik, Shoaib Ahmad; Albrecht, Christiane (2021). Dysregulated Autophagy Leads to Oxidative Stress and Aberrant Expression of ABC Transporters in Women with Early Miscarriage. Antioxidants, 10(11) MDPI 10.3390/antiox10111742

Stoklosa, Paulina; Borgström, Anna; Hauert, Barbara; Baur, Roland; Peinelt, Christine (2021). Investigation of Novel Small Molecular TRPM4 Inhibitors in Colorectal Cancer Cells. Cancers, 13(21) MDPI AG 10.3390/cancers13215400

Hoffmann, Patrick C; Giandomenico, Stefano L; Ganeva, Iva; Wozny, Michael R; Sutcliffe, Magdalena; Lancaster, Madeline A; Kukulski, Wanda (2021). Electron cryo-tomography reveals the subcellular architecture of growing axons in human brain organoids. eLife, 10 eLife Sciences Publications 10.7554/eLife.70269

Luca, Simon Vlad; Gaweł-Bęben, Katarzyna; Strzępek-Gomółka, Marcelina; Czech, Karolina; Trifan, Adriana; Zengin, Gokhan; Korona-Glowniak, Izabela; Minceva, Mirjana; Gertsch, Jürg; Skalicka-Woźniak, Krystyna (2021). Insights into the Phytochemical and Multifunctional Biological Profile of Spices from the Genus Piper. Antioxidants, 10(10) MDPI 10.3390/antiox10101642

Anghel, Nicoleta; Müller, Joachim; Serricchio, Mauro; Jelk, Jennifer; Bütikofer, Peter; Boubaker, Ghalia; Imhof, Dennis; Ramseier, Jessica; Desiatkina, Oksana; Paunescu, Emilia; Braga, Sophie Marie-Pierre; Heller, Manfred; Furrer, Julien; Hemphill, Andrew (2021). Cellular and Molecular Targets of Nucleotide-Tagged Trithiolato-Bridged Arene Ruthenium Complexes in the Protozoan Parasites Toxoplasma gondii and Trypanosoma brucei. International journal of molecular sciences, 22(19) Molecular Diversity Preservation International MDPI 10.3390/ijms221910787

Zaugg, Jonas; Ziegler, Fabian; Nuoffer, Jean-Marc; Moser-Hässig, Ruedi; Albrecht, Christiane (2021). Counter-directed leucine gradient promotes amino acid transfer across the human placenta. The journal of nutritional biochemistry, 96, p. 108760. Elsevier 10.1016/j.jnutbio.2021.108760

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Kalbermatter, David; Chiu, Po-Lin; Jeckelmann, Jean-Marc; Ucurum Fotiadis, Zöhre; Walz, Thomas; Fotiadis, Dimitrios José (2017). Electron crystallography reveals that substrate release from the PTS IIC glucose transporter is coupled to a subtle conformational change. Journal of structural biology, 199(1), pp. 39-45. Elsevier 10.1016/j.jsb.2017.05.005

von Rotz, Robin; Kometer, Michael; Dornbierer, Dario; Gertsch, Jürg; Gachet Otanez, Maria Salomé; Vollenweider, Franz X; Seifritz, Erich; Bosch, Oliver G; Quednow, Boris B (2017). Neuronal oscillations and synchronicity associated with gamma-hydroxybutyrate during resting-state in healthy male volunteers. Psychopharmacology, 234(13), pp. 1957-1968. Springer 10.1007/s00213-017-4603-z

Chicca, Andrea; Nicolussi, Simon; Bartholomäus, Ruben; Blunder, Martina; Aparisi Rey, Alejandro; Petrucci, Vanessa; Reynoso, Ines del Carmen; Viveros-Paredes, Juan Manuel; Dalghi Gens, Marianela Gisela; Lutz, Beat; Schiöth, Helgi B; Soeberdt, Michael; Abels, Christoph; Charles, Roch-Philippe; Altmann, Karl-Heinz; Gertsch, Jürg (2017). Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 114(25), E5006-E5015. National Academy of Sciences NAS 10.1073/pnas.1704065114

Peng, J-B; Suzuki, Y; Gyimesi, Gergely; Hediger, Matthias (2017). TRPV5 and TRPV6 calcium-selective channels. In: Ashot Kozak, Juliusz; Putney, James Jr. (eds.) Calcium Entry Channels in Non-Excitable Cells. Methods in Signal Transduction Series (pp. 241-274). CRC Press

Gertsch, Jürg (2017). Cannabimimetic phytochemicals in the diet - an evolutionary link to food selection and metabolic stress adaptation? British journal of pharmacology, 174(11), pp. 1464-1483. Wiley-Blackwell 10.1111/bph.13676

Nisa Hernández, Lluís; Häfliger, Pascal; Poliakova, Michaela; Giger, Roland; Francica, Paola; Aebersold, Daniel; Charles, Roch-Philippe; Zimmer, Yitzhak; Medova, Michaela (2017). PIK3CA hotspot mutations differentially impact responses to MET targeting in MET-driven and non-driven preclinical cancer models. Molecular cancer, 16(1), p. 93. BioMed Central 10.1186/s12943-017-0660-5

Pfreundschuh, Moritz; Harder, Daniel; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José; Müller, Daniel J (2017). Detecting Ligand-Binding Events and Free Energy Landscape while Imaging Membrane Receptors at Subnanometer Resolution. Nano letters, 17(5), pp. 3261-3269. American Chemical Society 10.1021/acs.nanolett.7b00941

Farine, Luce; Jelk, Jennifer; Choi, Jae-Yeon; Voelker, Dennis R; Nunes, Jon; Smith, Terry K; Bütikofer, Peter (2017). Phosphatidylserine synthase 2 and phosphatidylserine decarboxylase are essential for aminophospholipid synthesis in Trypanosoma brucei. Molecular microbiology, 104(3), pp. 412-427. Blackwell Science 10.1111/mmi.13637

Orekhov, Philipp; Bothe, Arne; Steinhoff, Heinz-Jürgen; Shaitan, Konstantin V; Raunser, Stefan; Fotiadis, Dimitrios José; Schlesinger, Ramona; Klare, Johann P; Engelhard, Martin (2017). Sensory Rhodopsin I and Sensory Rhodopsin II Form Trimers of Dimers in Complex with their Cognate Transducers. Photochemistry and photobiology, 93(3), pp. 796-804. Blackwell Publishing 10.1111/php.12763

Hinard, Valérie; Britan, Aurore; Schaeffer, Mathieu; Zahn-Zabal, Monique; Thomet, Urs; Rougier, Jean-Sébastien; Bairoch, Amos; Abriel, Hugues; Gaudet, Pascale (2017). Annotation of functional impact of voltage-gated sodium channel mutations. Human mutation, 38(5), pp. 485-493. Wiley-Blackwell 10.1002/humu.23191

El Mokh, Oussama; Ruffieux-Daidié, Dorothée; Rölli, Matthias Andreas; Stooss, Amandine; Phillips, Wayne A; Gertsch, Jürg; Dettmer, Matthias; Charles, Roch-Philippe (2017). Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo. OncoTarget, 8(15), pp. 24604-24620. Impact Journals LLC 10.18632/oncotarget.15599

Steinmann, Michael Eduard; Schmidt, Remo S; Bütikofer, Peter; Mäser, Pascal; Sigel, Erwin (2017). TbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes. Scientific Reports, 7(1), p. 656. Nature Publishing Group 10.1038/s41598-017-00752-1

Russo-Abrahão, Thais; Koeller, Carolina Macedo; Steinmann, Michael Eduard; Silva-Rito, Stephanie; Marins-Lucena, Thaissa; Alves-Bezerra, Michele; Lima-Giarola, Naira Ligia; de-Paula, Iron Francisco; González Salgado, Amaia; Sigel, Erwin; Bütikofer, Peter; Gondim, Katia Calp; Heise, Norton; Meyer-Fernandes, José Roberto (2017). H+-dependent inorganic phosphate uptake in Trypanosoma brucei is influenced by myo-inositol transporter. Journal of bioenergetics and biomembranes, 49(2), pp. 183-194. Springer 10.1007/s10863-017-9695-y

Vermij, Sarah Helena; Abriel, Hugues; van Veen, Toon A B (2017). Refining the molecular organization of the cardiac intercalated disc. Cardiovascular research, 113(3), pp. 259-275. Oxford University Press 10.1093/cvr/cvw259

Maldifassi, Maria Constanza; Sigel, Erwin (2017). Functional sites for anesthetics in GABAA receptors. OncoTarget, 8(7), pp. 10779-10780. Impact Journals LLC 10.18632/oncotarget.14616

Lochner, Martin; Hemmings, Jennifer Luise; Leuenberger, Michele; Meyer, Jonas; Bartlome, Pascal; Perozzo, Alyssa Victoria; Frenguelli, Bruno G.; Winfield, Ian; Ladds, Graham (12 February 2017). Molecular Tools for the Cellular Study of Adenosine A1 Receptors (Unpublished). In: GDCh/SCS conference on Frontiers in Medicinal Chemistry. Bern. 12.-15.02.2017.

Leuenberger, Michele; Lochner, Martin; Bernhard, Stephanie; Stieger, Bruno (12 February 2017). Synthesis of Fluorescent Bile Salt Derivatives and Their Utility as Tracers of the Canalicular Lipid Transporter System (Unpublished). In: GDCh/SCS conference on Frontiers in Medicinal Chemistry. Bern. 12.-15.2.2017.

Ruepp, Marc-David; Wei, Hao; Leuenberger, Michele; Lochner, Martin; Thompson, Andrew James (2017). The binding orientation of structurally-related ligands can differ; A cautionary note. Neuropharmacology, 119, pp. 48-61. Elsevier 10.1016/j.neuropharm.2017.01.023

Gachet Otanez, Maria Salomé; Schubert, Alexandra; Calarco, Serafina; Boccard, Julien; Gertsch, Jürg (2017). Targeted metabolomics shows plasticity in the evolution of signaling lipids and uncovers old and new endocannabinoids in the plant kingdom. Scientific Reports, 7, p. 41177. Nature Publishing Group 10.1038/srep41177

Thompson, Andrew J.; Metzger, Simon; Lochner, Martin; Ruepp, Marc-David (2017). The binding orientation of epibatidine at α7 nACh receptors. Neuropharmacology, 116, pp. 421-428. Elsevier 10.1016/j.neuropharm.2017.01.008

Ontsouka, Edgar; Huang, Xiao; Aliyev, Eldar; Albrecht, Christiane (2017). In vitro characterization and endocrine regulation of cholesterol and phospholipid transport in the mammary gland. Molecular and cellular endocrinology, 439, pp. 35-45. Elsevier Ireland 10.1016/j.mce.2016.10.016

Mathieu, Christoph; Pereira de Macêdo, Juan; Hürlimann, Daniel; Wirdnam, Corina; Haindrich, Alexander; Suter, Marianne; González Salgado, Amaia; Schmidt, Remo; Inbar, Ehud; Mäser, Pascal; Bütikofer, Peter; Zilberstein, Dan; Rentsch, Doris (2017). Arginine and Lysine Transporters Are Essential for Trypanosoma brucei. PLoS ONE, 12(1), e0168775. Public Library of Science 10.1371/journal.pone.0168775

Soethoudt, Marjolein; Grether, Uwe; Fingerle, Jürgen; Grim, Travis W; Fezza, Filomena; de Petrocellis, Luciano; Ullmer, Christoph; Rothenhäusler, Benno; Perret, Camille; van Gils, Noortje; Finlay, David; MacDonald, Christa; Chicca, Andrea; Gens, Marianela Dalghi; Stuart, Jordyn; de Vries, Henk; Mastrangelo, Nicolina; Xia, Lizi; Alachouzos, Georgios; Baggelaar, Marc P; ... (2017). Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity. Nature communications, 8(13958), p. 13958. Nature Publishing Group 10.1038/ncomms13958

Gottier, Petra; González Salgado, Amaia; Menon, Anant K; Liu, Yuk-Chien; Acosta-Serrano, Alvaro; Bütikofer, Peter (2017). RFT1 affects GPI anchor glycosylation. Journal of biological chemistry, 292(3), pp. 1103-1111. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M116.758367

Albano, Giuseppe; Dolder, Silvia; Siegrist, Mark; Mercier-Zuber, Annie; Auberson, Muriel; Stoudmann, Candice; Hofstetter, Wilhelm; Bonny, Olivier; Fuster, Daniel Guido (2017). Increased bone resorption by osteoclast-specific deletion of the sodium/calcium exchanger isoform 1 (NCX1). Pflügers Archiv : European journal of physiology, 469(2), pp. 225-233. Springer 10.1007/s00424-016-1923-5

Martínez-Pacheco, Heidy; Ramírez-Galicia, Guillermo; Vergara-Arias, Midalia; Gertsch, Jürg; Fragoso-Vázquez, Jonathan Manuel; Méndez-Luna, David; Abujamra, A L; Cristina, Cabrera-Pérez Laura; Cecilia, Rosales-Hernández Martha; Mendoza-Lujambio, I; Correa-Basurto, José (2017). Docking and QSAR studies of aryl-valproic acid derivatives to identify anti-proliferative agents targeting the HDAC8. Anti-cancer agents in medicinal chemistry, 17(7), pp. 927-940. Bentham Science Publishers

Chen, Songjie; Huang, Xiao; Decurtins, Silvio; Albrecht, Christiane; Liu, Shi-Xia (2017). A terpy-functionalized benzodifuran-based fluorescent probe for in vitro monitoring cellular Zn(II) uptake. Polyhedron, 134, pp. 287-294. Elsevier 10.1016/j.poly.2017.06.037

Kind, Marcus Johann; Klukowska-Rötzler, Jolanta; Berezowska, Sabina Anna; Arcaro, Alexandre; Charles, Roch-Philippe (2017). Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis. PLoS ONE, 12(10), e0187308. Public Library of Science 10.1371/journal.pone.0187308

Baur, Roland; Sigel, Erwin (2017). Low Expression in Xenopus Oocytes and Unusual Functional Properties of α1β2γ2 GABAA Receptors with Non-Conventional Subunit Arrangement. PLoS ONE, 12(1), e0170572. Public Library of Science 10.1371/journal.pone.0170572


Maldifassi, Maria Constanza; Wongsamitkul, Nisa; Baur, Roland; Sigel, Erwin (2016). Xenopus Oocytes: Optimized Methods for Microinjection, Removal of Follicular Cell Layers, and Fast Solution Changes in Electrophysiological Experiments. Journal of visualized experiments(118) MYJoVE Corporation 10.3791/55034

Deisl, Christine; Anderegg, Manuel; Albano, Giuseppe; Lüscher, Benjamin; Cerny, David; Soria Maldonado, Rodrigo; Bouillet, Elisa; Rimoldi, Stefano; Scherrer, Urs; Fuster, Daniel Guido (2016). Loss of Sodium/Hydrogen Exchanger NHA2 Exacerbates Obesity- and Aging-Induced Glucose Intolerance in Mice. PLoS ONE, 11(9), e0163568. Public Library of Science 10.1371/journal.pone.0163568

Ilgü, Hüseyin; Jeckelmann, Jean-Marc; Gapsys, Vytautas; Ucurum Fotiadis, Zöhre; de Groot, Bert L; Fotiadis, Dimitrios José (2016). Insights into the molecular basis for substrate binding and specificity of the wild-type L-arginine/agmatine antiporter AdiC. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(37), pp. 10358-10363. National Academy of Sciences NAS 10.1073/pnas.1605442113

Alferink, Judith; Specht, Sabine; Arends, Hannah; Schumak, Beatrix; Schmidt, Kim; Ruland, Christina; Lundt, Ramona; Kemter, Andrea; Dlugos, Andrea; Kuepper, Janina M; Poppensieker, Karola; Findeiss, Matthias; Albayram, Önder; Otte, David-M; Marazzi, Janine; Gertsch, Jürg; Förster, Irmgard; Maier, Wolfgang; Scheu, Stefanie; Hoerauf, Achim; ... (2016). Cannabinoid Receptor 2 Modulates Susceptibility to Experimental Cerebral Malaria through a CCL17-dependent Mechanism. Journal of biological chemistry, 291(37), pp. 19517-19531. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M116.746594

Bertran-Vicente, Jordi; Penkert, Martin; Nieto-Garcia, Olaia; Jeckelmann, Jean-Marc; Schmieder, Peter; Krause, Eberhard; Hackenberger, Christian P R (2016). Chemoselective synthesis and analysis of naturally occurring phosphorylated cysteine peptides. Nature communications, 7, p. 12703. Nature Publishing Group 10.1038/ncomms12703

Maldifassi, Maria Constanza; Baur, Roland; Sigel, Erwin (2016). Molecular mode of action of CGS 9895 at α1 β2 γ2 GABAA receptors. Journal of neurochemistry, 138(5), pp. 722-730. Wiley 10.1111/jnc.13711

Mu, Linjing; Müller Herde, Adrienne; Rüefli, Pascal; Sladojevich, Filippo; Sephton, Selena Milicevic; Krämer, Stefanie D.; Thompson, Andrew James; Schibli, Roger; Ametamey, Simon M.; Lochner, Martin (2016). Synthesis and Pharmacological Evaluation of [11C]granisetron and [18F]fluoropalonosetron as PET Probes for 5-HT3 Receptor Imaging. ACS chemical neuroscience, 7(11), pp. 1552-1564. American Chemical Society 10.1021/acschemneuro.6b00192

Wongsamitkul, Nisa; Baur, Roland; Sigel, Erwin (2016). Toward Understanding Functional Properties and Subunit Arrangement of α4β2δ γ-Aminobutyric Acid, Type A (GABAA) Receptors. Journal of biological chemistry, 291(35), pp. 18474-18483. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M116.738906

Eichel, Catherine A; Beuriot, Adeline; Chevalier, Morgan Yoann Edwin; Rougier, Jean-Sébastien; Louault, Florent; Dilanian, Gilles; Amour, Julien; Coulombe, Alain; Abriel, Hugues; Hatem, Stéphane N; Balse, Elise (2016). Lateral Membrane-Specific MAGUK CASK Down-Regulates NaV1.5 Channel in Cardiac Myocytes. Circulation research, 119(4), pp. 544-556. Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.116.309254

Jantsch, Andrea; Nieto, Lidia; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth; Jiménez-Barbero, Jesús; Díaz, J Fernando; Canales, Ángeles; Altmann, Karl-Heinz (2016). Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones). Molecules, 21(8) Molecular Diversity Preservation International MDPI 10.3390/molecules21081010

Clemençon, Benjamin; Fine, Michael; Hediger, Matthias (2016). Conservation of the oligomeric state of native VDAC1 in detergent micelles. Biochimie, 127, pp. 163-172. Elsevier Masson SAS 10.1016/j.biochi.2016.05.015

Lochner, Martin; Jack, Thomas; Simonin, Jonathan; Leuenberger, Michele; Rüefli, Pascal; Bur-Cecilio Hechavarria, Yamileidi; Ruepp, Marc-David; Thompson, Andrew J. (August 2016). Investigation of the interaction between 5-HT3R and its modulators: progress in understanding the agonist binding site. CHIMIA, 70(7/8), MC121. Schweizerische Chemische Gesellschaft

Leuenberger, Michele; Ritler, Andreas; Aerni, Valerie; Metzger, Simon G.; Ruepp, Marc-David; Lochner, Martin (August 2016). New insights into glutamate transport in brain: Concise asymmetric synthesis of TFB-TBOA and photoaffinity probes. CHIMIA, 70(7/8), MC123. Schweizerische Chemische Gesellschaft

Schild, Achille; Tscherrig, Dominic Armin; Wenger, Nicolas; Rajesh, Rajesh; Lüscher, Benjamin; Hediger, Matthias; Lochner, Martin (August 2016). Design, synthesis and pharmacological characterization of novel store-operated calcium channel (SOCE) modulators. CHIMIA, 70(7/8), MC125. Schweizerische Chemische Gesellschaft

Gambaro, Giovanni; Croppi, Emanuele; Coe, Fredric; Lingeman, James; Moe, Orson; Worcester, Elen; Buchholz, Noor; Bushinsky, David; Curhan, Gary C; Ferraro, Pietro Manuel; Fuster, Daniel Guido; Goldfarb, David S; Heilberg, Ita Pfeferman; Hess, Bernard; Lieske, John; Marangella, Martino; Milliner, Dawn; Preminger, Glen M; Reis Santos, Jose' Manuel; Sakhaee, Khashayar; ... (2016). Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement. Journal of nephrology JN, 29(6), pp. 715-734. Springer 10.1007/s40620-016-0329-y

Harder, Daniel; Hirschi, Stephan; Ucurum Fotiadis, Zöhre; Goers, Roland; Meier, Wolfgang; Müller, Daniel J; Fotiadis, Dimitrios José (2016). Engineering a Chemical Switch into the Light-driven Proton Pump Proteorhodopsin by Cysteine Mutagenesis and Thiol Modification. Angewandte Chemie (International ed.), 55(31), pp. 8846-8849. Wiley-VCH 10.1002/anie.201601537

Gertsch, Jürg (2016). The Metabolic Plant Feedback Hypothesis: How Plant Secondary Metabolites Nonspecifically Impact Human Health. Planta medica, 82(11-12), pp. 920-929. Thieme 10.1055/s-0042-108340

Bertini, Simone; Chicca, Andrea; Arena, Chiara; Chicca, Stefano; Saccomanni, Giuseppe; Gertsch, Jürg; Manera, Clementina; Macchia, Marco (2016). Synthesis and pharmacological evaluation of new biphenylic derivatives as CB2 receptor ligands. European journal of medicinal chemistry, 116, pp. 252-266. Elsevier Masson SAS 10.1016/j.ejmech.2016.03.072

Huang, Xiao; Lüthi, Michael; Ontsouka, Edgar; Kallol, Sampada Arvindrao; Baumann, Marc Ulrich; Surbek, Daniel; Albrecht, Christiane (2016). Establishment of a confluent monolayer model with human primary trophoblast cells: novel insights into placental glucose transport. Molecular human reproduction MHR, 22(6), pp. 442-456. Oxford University Press 10.1093/molehr/gaw018

Dhayat, Nasser; Ackermann, Daniel; Pruijm, Menno; Ponte, Belen; Ehret, Georg; Guessous, Idris; Leichtle, Alexander Benedikt; Paccaud, Fred; Mohaupt, Markus; Fiedler, Martin; Devuyst, Olivier; Pechère-Bertschi, Antoinette; Burnier, Michel; Martin, Pierre-Yves; Bochud, Murielle; Vogt, Bruno; Fuster, Daniel Guido (2016). Fibroblast growth factor 23 and markers of mineral metabolism in individuals with preserved renal function. Kidney international, 90(3), pp. 648-657. Elsevier 10.1016/j.kint.2016.04.024

Hirschi, Stephan; Stauffer, Mirko; Harder, Daniel; Müller, Daniel J; Meier, Wolfgang; Fotiadis, Dimitrios José (2016). Engineering and Assembly of Protein Modules into Functional Molecular Systems. CHIMIA, 70(6), pp. 398-401. Schweizerische Chemische Gesellschaft 10.2533/chimia.2016.398

Wellnitz, Olga; Zbinden, Christina; Huang, Xiao; Bruckmaier, Rupert (2016). Short communication: Differential loss of bovine mammary epithelial barrier integrity in response to lipopolysaccharide and lipoteichoic acid. Journal of dairy science, 99(6), pp. 4851-4856. American Dairy Science Association 10.3168/jds.2016-10927

Maldifassi, Maria Constanza; Baur, Roland; Pierce, David; Nourmahnad, Anahita; Forman, Stuart A; Sigel, Erwin (2016). Novel positive allosteric modulators of GABAA receptors with anesthetic activity. Scientific Reports, 6(25943), p. 25943. Nature Publishing Group 10.1038/srep25943

Lochner, Martin; Thompson, Andrew James (2016). The muscarinic antagonists scopolamine and atropine are competitive antagonists at 5-HT3 receptors. Neuropharmacology, 108, pp. 220-228. Elsevier 10.1016/j.neuropharm.2016.04.027

Eisele, Nicole; Albrecht, Christiane; Mistry, Hiten Dhirubhai; Dick, Bernhard; Baumann, Marc Ulrich; Surbek, Daniel; Currie, Gemma; Delles, Christian; Mohaupt, Markus; Escher, Geneviève; Gennari-Moser, Carine (2016). Placental expression of the angiogenic placental growth factor is stimulated by both aldosterone and simulated starvation. Placenta, 40, pp. 18-24. Elsevier 10.1016/j.placenta.2016.02.004

Oláh, Attila; Ambrus, Lídia; Nicolussi, Simon; Gertsch, Jürg; Tubak, Vilmos; Kemény, Lajos; Soeberdt, Michael; Abels, Christoph; Bíró, Tamás (2016). Inhibition of fatty acid amide hydrolase exerts cutaneous anti-inflammatory effects both in vitro and in vivo. Experimental dermatology, 25(4), pp. 328-330. Blackwell 10.1111/exd.12930

Gross, Josef Johann; Schwinn, Ann-Catherine; Schmitz-Hsu, F; Menzi, Fiona; Drögemüller, Cord; Albrecht, Christiane; Bruckmaier, Rupert (2016). Rapid Communication: Cholesterol deficiency-associated APOB mutation impacts lipid metabolism in Holstein calves and breeding bulls. Journal of animal science, 94(4), pp. 1761-1766. American Society of Animal Science 10.2527/jas.2016-0439

Gertsch, Jürg (2016). Editorial: Lung macrophages high on cannabinoids: jamming PAMs and taming TAMs? Journal of leukocyte biology, 99(4), pp. 518-520. Society for Leukocyte Biology 10.1189/jlb.3CE0915-409RR

Ross, Daniela; Altmann, Michael (2016). A fast protocol for purification of translating mRNAs. Methods, 107, pp. 57-62. Elsevier 10.1016/j.ymeth.2016.03.021

Rajesh, Rajesh; Hediger, Matthias; Demaurex, Nicolas (2016). Redox modulation of STIM-ORAI signaling. Cell calcium, 60(2), pp. 142-152. Elsevier 10.1016/j.ceca.2016.03.006

Dörr, Kathrin; Kilch, Tatiana; Kappel, Sven; Alansary, Dalia; Schwär, Gertrud; Niemeyer, Barbara A; Peinelt, Christine (2016). Cell type-specific glycosylation of Orai1 modulates store-operated Ca2+ entry. Science signaling, 9(418), ra25. American Association for the Advancement of Science 10.1126/scisignal.aaa9913

Chauhan, Neha; Farine, Luce; Pandey, Kalpana; Menon, Anant K; Bütikofer, Peter (2016). Lipid topogenesis - 35 years on. Biochimica et biophysica acta (BBA) - molecular and cell biology of lipids, 1861(8), pp. 757-766. Elsevier 10.1016/j.bbalip.2016.02.025

Leuenberger, Michele; Ritler, Andreas; Simonin, Alexandre; Hediger, Matthias; Lochner, Martin (2016). Concise Asymmetric Synthesis and Pharmacological Characterization of All Stereoisomers of Glutamate Transporter Inhibitor TFB-TBOA and Synthesis of EAAT Photoaffinity Probes. ACS chemical neuroscience, 7(5), pp. 534-539. American Chemical Society 10.1021/acschemneuro.5b00311

Crockett, Sara; Baur, Roland; Kunert, Olaf; Belaj, Ferdinand; Sigel, Erwin (2016). A new chromanone derivative isolated from Hypericum lissophloeus (Hypericaceae) potentiates GABAA receptor currents in a subunit specific fashion. Bioorganic & medicinal chemistry, 24(4), pp. 681-685. Elsevier 10.1016/j.bmc.2015.12.037

Ontsouka, Edgar; Albrecht, Christiane; Bruckmaier, Rupert (2016). Invited review: Growth-promoting effects of colostrum in calves based on interaction with intestinal cell surface receptors and receptor-like transporters. Journal of dairy science, 99(6), pp. 4111-4123. American Dairy Science Association 10.3168/jds.2015-9741

Knight, Anthony; Hemmings, Jennifer Luise; Winfield, Ian; Leuenberger, Michele; Frattini, Eugenia; Frenguelli, Bruno G.; Dowell, Simon J.; Lochner, Martin; Ladds, Graham (2016). Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity. Journal of medicinal chemistry, 59(3), pp. 947-964. American Chemical Society 10.1021/acs.jmedchem.5b01402

Maldifassi, Maria Constanza; Baur, Roland; Sigel, Erwin (2016). Functional sites involved in modulation of the GABAA receptor channel by the intravenous anesthetics propofol, etomidate and pentobarbital. Neuropharmacology, 105, pp. 207-214. Elsevier 10.1016/j.neuropharm.2016.01.003

Albrecht, Christiane; Caniggia, I; Clifton, V; Göhner, C; Harris, L; Hemmings, D; Jawerbaum, A; Johnstone, E; Jones, H; Keelan, J; Lewis, R; Mitchell, M; Murthi, P; Powell, T; Saffery, R; Smith, R; Vaillancourt, C; Wadsack, C; Salomon, C (2016). IFPA meeting 2015 workshop report IV: Nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid mediators and placental function. Placenta, 48 Suppl 1, S12-S16. Elsevier 10.1016/j.placenta.2016.01.003

Ontsouka, Edgar; Bertschi, Janique Sabina; Huang, Xiao; Lüthi, Michael; Müller, Stefan Jürg; Albrecht, Christiane (2016). Can widely used cell type markers predict the suitability of immortalized or primary mammary epithelial cell models? Biological research, 49(1), p. 1. BioMed Central 10.1186/s40659-015-0063-2

Simon, Hans-Uwe; Tschan, Mario P.; Bütikofer, Peter (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12(1), pp. 1-222. Landes Bioscience 10.1080/15548627.2015.1100356

Rau, Mark; Nicolussi, Simon; Chicca, Andrea; Gertsch, Jürg (2016). Assay of Endocannabinoid Uptake. In: Maccarrone, Mauro (ed.) Endocannabinoid Signaling. Methods and Protocols. Methods in Molecular Biology: Vol. 1412 (pp. 191-203). New York: Springer 10.1007/978-1-4939-3539-0_20

Boggavarapu, Venkata Ravi Naga Rajendr; Hirschi, Stephan; Harder, Daniel; Meury, Marcel; Ucurum Fotiadis, Zöhre; Bergeron, Marc; Fotiadis, Dimitrios José (2016). Purification of Human and Mammalian Membrane Proteins Expressed in Xenopus laevis Frog Oocytes for Structural Studies. In: Mus-Veteau, Isabelle (ed.) Heterologous Expression of Membrane Proteins. Methods and Protocols. Methods in Molecular Biology: Vol. 1432 (pp. 223-242). New York: Springer 10.1007/978-1-4939-3637-3_14

Eltschinger, Sandra; Bütikofer, Peter; Altmann, Michael (2016). Translation Elongation and Termination: 2 Are They Conserved Processes? In: Hernández, Greco; Jagus, Rosemary (eds.) Evolution of The Protein Synthesis Machinery and Its Regulation (pp. 277-311). Springer International 10.1007/978-3-319-39468-8_13

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Charles, Roch-Philippe; Silva, Jilian; Iezza, Gioia; Phillips, Wayne A; McMahon, Martin (2013). BRAF V600E and PIK3CA H1074R cooperate to promote progression of anaplastic thyroid carcinoma in the mouse. Endocrine abstracts, 32(S16.1) BioScientifica 10.1530/endoabs.32.s16.1


Stanisz, Hedwig; Stark, Alexandra; Kilch, Tatiana; Schwarz, Eva C; Müller, Cornelia S L; Peinelt, Christine; Hoth, Markus; Niemeyer, Barbara A; Vogt, Thomas; Bogeski, Ivan (2012). ORAI1 Ca(2+) channels control endothelin-1-induced mitogenesis and melanogenesis in primary human melanocytes. Journal of Investigative Dermatology, 132(5), pp. 1443-1451. Nature Publishing 10.1038/jid.2011.478

Gertsch, Jürg (2012). Cross-cultural comparisons of medicinal floras--what are the implications for bioprospecting? Journal of ethnopharmacology, 139(3), 685-7; discussion 688-90. Shannon: Elsevier Science Ireland 10.1016/j.jep.2011.09.017

Stach, Michaela; Maillard, Noélie; Kadam, Rameshwar; Kalbermatter, David; Meury, M.; Page, Malcolm; Fotiadis, Dimitrios José; Darbre, Tamis; Reymond, Jean-Louis (2012). Membrane disrupting antimicrobial peptide dendrimers with multiple amino termini. Medicinal chemistry communications - MedChemComm, 3(1), pp. 86-89. Cambridge: Royal Society of Chemistry 10.1039/c1md00272d

Eltschinger, Sandra; Greganova, Eva; Heller, Manfred; Bütikofer, Peter; Altmann, Michael (2012). Eukaryotic translation elongation factor 1A (eEF1A) domain I from S. cerevisiae is required but not sufficient for inter-species complementation. PLoS ONE, 7(7), e42338. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0042338

Bürzle, Marc; Hediger, Matthias A (2012). Functional and physiological role of vitamin C transporters. Current topics in membranes, 70, pp. 357-375. San Diego, Calif.: Academic Press 10.1016/B978-0-12-394316-3.00011-9

Kovacs, Gergely; Montalbetti, Nicolas; Simonin, Alexandre; Danko, Tamas; Balazs, Bernadett; Zsembery, Akos; Hediger, Matthias A (2012). Inhibition of the human epithelial calcium channel TRPV6 by 2-aminoethoxydiphenyl borate (2-APB). Cell calcium, 52(6), pp. 468-80. Amsterdam: Elsevier 10.1016/j.ceca.2012.08.005

Ross, Daniela; Saxena, Manisha; Altmann, Michael (2012). eIF4E is an important determinant of adhesion and pseudohyphal growth of the yeast S. cerevisiae. PLoS ONE, 7(11), e50773. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0050773

Christensen, Jon; El-Gebali, Sara; Natoli, Manuela; Sengstag, Thierry; Delorenzi, Mauro; Bentz, Susanne; Bouzourene, Hanifa; Rumbo, Martin; Felsani, Armando; Siissalo, Sanna; Hirvonen, Jouni; Vila, Maya R; Saletti, Piercarlo; Aguet, Michel; Anderle, Pascale (2012). Defining new criteria for selection of cell-based intestinal models using publicly available databases. BMC Genomics, 13, p. 274. London: BioMed Central 10.1186/1471-2164-13-274

Kleyer, Jonas; Nicolussi, Simon; Taylor, Peter; Simonelli, Deborah; Furger, Evelyne; Anderle, Pascale; Gertsch, Jürg (2012). Cannabinoid receptor trafficking in peripheral cells is dynamically regulated by a binary biochemical switch. Biochemical pharmacology, 83(10), pp. 1393-412. New York, N.Y.: Elsevier 10.1016/j.bcp.2012.02.014

Ao, Zihua; Quezada-Calvillo, Roberto; Nichols, Buford L; Rose, David R; Sterchi, Erwin E; Hamaker, Bruce R (2012). The nature of raw starch digestion. Journal of pediatric gastroenterology and nutrition, 55 Suppl 2, S42-S43. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/01.mpg.0000421413.18623.f9

Gilger, Mark; Hamaker, Bruce; Nichols, Buford L; Auricchio, Salvatore; Treem, William R; Naim, Hassan Y; Heine, Martin; Zimmer, Klaus-Peter; Jones, Kyra; Eskandari, Razieh; Pinto, B Mario; Rose, David R; Lee, Byung-Hoo; Quezada-Calvillo, Roberto; Adams, Bridget; Roach, Christine M; Ma, Chang-Xing; Baker, Susan S; Slawson, Mary H; Robayo-Torres, Claudia C; ... (2012). Research progress reported at the 50th Anniversary of the Discovery of Congenital Sucrase-Isomaltase Deficiency Workshop. Journal of pediatric gastroenterology and nutrition, 55 Suppl 2(0 2), S1. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/00005176-199507000-00001

Arolas, Joan L; Broder, Claudia; Jefferson, Tamara; Guevara, Tibisay; Sterchi, Erwin E; Bode, Wolfram; Stöcker, Walter; Becker-Pauly, Christoph; Gomis-Rüth, F Xavier (2012). Structural basis for the sheddase function of human meprin β metalloproteinase at the plasma membrane. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 109(40), pp. 16131-6. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.1211076109

Minder, Petra; Bayha, Elke; Becker-Pauly, Christoph; Sterchi, Erwin E (2012). Meprinα transactivates the epidermal growth factor receptor (EGFR) via ligand shedding, thereby enhancing colorectal cancer cell proliferation and migration. Journal of biological chemistry, 287(42), pp. 35201-11. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.368910

Serricchio, Mauro; Bütikofer, Peter (2012). An essential bacterial-type cardiolipin synthase mediates cardiolipin formation in a eukaryote. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 109(16), E954-61. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.1121528109

Greganova, Eva; Bütikofer, Peter (2012). Ethanolamine phosphoglycerol attachment to eEF1A is not essential for normal growth of Trypanosoma brucei. Scientific Reports, 2, p. 254. London: Nature Publishing Group 10.1038/srep00254

Gonzalez-Salgado, Amaia; Steinmann, Michael E; Greganova, Eva; Rauch, Monika; Mäser, Pascal; Sigel, Erwin; Bütikofer, Peter (2012). myo-Inositol uptake is essential for bulk inositol phospholipid but not glycosylphosphatidylinositol synthesis in Trypanosoma brucei. Journal of biological chemistry, 287(16), pp. 13313-23. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.344812

Sigel, Erwin; Steinmann, Michael E (2012). Structure, function, and modulation of GABA(A) receptors. Journal of biological chemistry, 287(48), pp. 40224-31. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.R112.386664

Stein, Marco; Middendorp, Simon J; Carta, Valentina; Pejo, Ervin; Raines, Douglas E; Forman, Stuart A; Sigel, Erwin; Trauner, Dirk (2012). Azo-propofols: photochromic potentiators of GABA(A) receptors. Angewandte Chemie (International ed.), 51(42), pp. 10500-4. Weinheim: Wiley-VCH 10.1002/anie.201205475

Lüscher, Benjamin P; Baur, Roland; Goeldner, Maurice; Sigel, Erwin (2012). Influence of GABA(A) receptor α subunit isoforms on the benzodiazepine binding site. PLoS ONE, 7(7), e42101. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0042101

Kuhn-Nentwig, Lucia; Fedorova, Irina M; Lüscher, Benjamin P; Kopp, Lukas; Trachsel, Christian; Schaller, Johann; Vu Nguyen, Xuan Lan; Seebeck, Thomas; Streitberger, Kathrin; Nentwig, Wolfgang; Sigel, Erwin; Magazanik, Lev G (2012). A venom-derived neurotoxin, CsTx-1, from the spider Cupiennius salei exhibits cytolytic activities. Journal of biological chemistry, 287(30), pp. 25640-25649. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.339051

Baur, R; Gertsch, J; Sigel, E (2012). The cannabinoid CB1 receptor antagonists rimonabant (SR141716) and AM251 directly potentiate GABA(A) receptors. British journal of pharmacology, 165(8), pp. 2479-84. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2011.01405.x

Harder, Daniel; Fotiadis, Dimitrios (2012). Measuring substrate binding and affinity of purified membrane transport proteins using the scintillation proximity assay. Nature protocols, 7(9), pp. 1569-78. London: Nature Publishing Group 10.1038/nprot.2012.090

Fotiadis, Dimitrios (2012). Atomic force microscopy for the study of membrane proteins. Current opinion in biotechnology, 23(4), pp. 510-5. Amsterdam: Elsevier 10.1016/j.copbio.2011.11.032

Bruning, Marc; Barsukov, Igor; Franke, Barbara; Barbieri, Sonia; Volk, Martin; Leopoldseder, Sonja; Ucurum, Zöhre; Mayans, Olga (2012). The intracellular Ig fold: a robust protein scaffold for the engineering of molecular recognition. Protein engineering, design & selection, 25(5), pp. 205-12. Oxford: Oxford University Press 10.1093/protein/gzs007

Zurwerra, Didier; Glaus, Florian; Betschart, Leo; Schuster, Julia; Gertsch, Jürg; Ganci, Walter; Altmann, Karl-Heinz (2012). Total synthesis of (-)-zampanolide and structure-activity relationship studies on (-)-dactylolide derivatives. Chemistry - a European journal, 18(52), pp. 16868-83. Weinheim: Wiley-VCH 10.1002/chem.201202553

Bauer, Mark; Chicca, Andrea; Tamborrini, Marco; Eisen, David; Lerner, Raissa; Lutz, Beat; Poetz, Oliver; Pluschke, Gerd; Gertsch, Jürg (2012). Identification and quantification of a new family of peptide endocannabinoids (Pepcans) showing negative allosteric modulation at CB1 receptors. Journal of biological chemistry, 287(44), pp. 36944-67. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.382481

Serra, Silvia; Chicca, Andrea; Delogu, Giovanna; Vázquez-Rodríguez, Saleta; Santana, Lourdes; Uriarte, Eugenio; Casu, Laura; Gertsch, Jürg (2012). Synthesis and cytotoxic activity of non-naturally substituted 4-oxycoumarin derivatives. Bioorganic and medicinal chemistry letters, 22(18), pp. 5791-4. New York, N.Y.: Pergamon 10.1016/j.bmcl.2012.07.099

Chicca, Andrea; Marazzi, Janine; Nicolussi, Simon; Gertsch, Jürg (2012). Evidence for bidirectional endocannabinoid transport across cell membranes. Journal of biological chemistry, 287(41), pp. 34660-82. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.373241

Chicca, A; Marazzi, J; Gertsch, J (2012). The antinociceptive triterpene β-amyrin inhibits 2-arachidonoylglycerol (2-AG) hydrolysis without directly targeting cannabinoid receptors. British journal of pharmacology, 167(8), pp. 1596-608. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2012.02059.x

Yang, Peng; Myint, Kyaw-Zeyar; Tong, Qin; Feng, Rentian; Cao, Haiping; Almehizia, Abdulrahman A; Alqarni, Mohammed Hamed; Wang, Lirong; Bartlow, Patrick; Gao, Yingdai; Gertsch, Jürg; Teramachi, Jumpei; Kurihara, Noriyoshi; Roodman, Garson David; Cheng, Tao; Xie, Xiang-Qun (2012). Lead discovery, chemistry optimization, and biological evaluation studies of novel biamide derivatives as CB2 receptor inverse agonists and osteoclast inhibitors. Journal of medicinal chemistry, 55(22), pp. 9973-87. Easton, Pa.: American Chemical Society 10.1021/jm301212u

Bénard, Giovanni; Massa, Federico; Puente, Nagore; Lourenço, Joana; Bellocchio, Luigi; Soria-Gómez, Edgar; Matias, Isabel; Delamarre, Anna; Metna-Laurent, Mathilde; Cannich, Astrid; Hebert-Chatelain, Etienne; Mulle, Christophe; Ortega-Gutiérrez, Silvia; Martín-Fontecha, Mar; Klugmann, Matthias; Guggenhuber, Stephan; Lutz, Beat; Gertsch, Jürg; Chaouloff, Francis; López-Rodríguez, María Luz; ... (2012). Mitochondrial CB₁ receptors regulate neuronal energy metabolism. Nature neuroscience, 15(4), pp. 558-64. New York, N.Y.: Nature America 10.1038/nn.3053

Horváth, Béla; Mukhopadhyay, Partha; Kechrid, Malek; Patel, Vivek; Tanchian, Galin; Wink, David A; Gertsch, Jürg; Pacher, Pál (2012). β-Caryophyllene ameliorates cisplatin-induced nephrotoxicity in a cannabinoid 2 receptor-dependent manner. Free radical biology & medicine, 52(8), pp. 1325-33. San Diego, Calif.: Elsevier 10.1016/j.freeradbiomed.2012.01.014

Anavi-Goffer, Sharon; Baillie, Gemma; Irving, Andrew J; Gertsch, Jürg; Greig, Iain R; Pertwee, Roger G; Ross, Ruth A (2012). Modulation of L-α-lysophosphatidylinositol/GPR55 mitogen-activated protein kinase (MAPK) signaling by cannabinoids. Journal of biological chemistry, 287(1), pp. 91-104. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M111.296020

Gertsch, J; Anavi-Goffer, S (2012). Methylhonokiol attenuates neuroinflammation: a role for cannabinoid receptors? 9. J Neuroinflammation 10.1186/1742-2094-9-135

Kuhn, A; Fotiadis, D (2012). Membrane proteins - at the core of life. Public service review - European science & technology, 17 Newcastle-under-Lyme, UK: publicservice.co.uk Ltd

Trachsel, Christian; Siegemund, Doreen; Kämpfer, Urs; Kopp, Lukas; Bühr, Claudia; Grossmann, Jonas; Lüthi, Christoph; Cunningham, Monica; Nentwig, Wolfgang; Kuhn-Nentwig, Lucia; Schürch, Stefan; Schaller, Johann (2012). Multicomponent venom of the spider Cupiennius salei: a bioanalytical investigation applying different strategies. FEBS journal, 279(15), pp. 2683-2694. Oxford: Wiley-Blackwell 10.1111/j.1742-4658.2012.08650.x

Acharya, G; Albrecht, C; Benton, S J; Cotechini, T; Dechend, R; Dilworth, M R; Duttaroy, A K; Grotmol, T; Heazell, A E; Jansson, T; Johnstone, E D; Jones, H N; Jones, R L; Lager, S; Laine, K; Nagirnaja, L; Nystad, M; Powell, T; Redman, C; Sadovsky, Y; ... (2012). IFPA Meeting 2011 workshop report I: Placenta: Predicting future health; roles of lipids in the growth and development of feto-placental unit; placental nutrient sensing; placental research to solve clinical problems--a translational approach. Placenta, 33 Suppl, S4-8. Amsterdam: Elsevier 10.1016/j.placenta.2011.11.015

Ontsouka, E.C.; Burgener, I.A.; Luckschander-Zeller, N; Blum, J.W.; Albrecht, C. (2012). Fish-meal diet enriched with omega-3 PUFA and treatment of canine chronic enteropathies. European journal of lipid science and technology, 2012(114), pp. 412-422. Weinheim: Wiley-Blackwell 10.1002/ejlt.201100343

Körner, Meike; Wenger, Fabian; Nikitina, Liudmila; Baumann, Marc; Surbek, Daniel; Albrecht, Christiane (2012). The lipid transporters ABCA1 and ABCG1 are differentially expressed in syncytiotrophoblasts of preeclamptic and IUGR placentas. Placenta, 2012(9), A91. Elsevier

Lüscher, Benjamin; Messerli, Marianne; Surbek, Daniel; Sager, Ruth; Albrecht, Christiane; Hediger, Matthias; Baumann, Marc (2012). Placental glucose transporter (Glut)-1 expression in preeclampsia. Placenta, 33(9), A90-A90. Elsevier

Eisele, Nicole; Gennari-Moser, Carine; Albrecht, Christiane; Baumann, Marc; Surbek, Daniel; Mohaupt, Markus (2012). Does Aldosterone participate in placental angiogenesis via PLGF? Pregnancy hypertension, 2(3), p. 245. Amsterdam: Elsevier 10.1016/j.preghy.2012.04.121

Körner, M; Wenger, F; NIkitina, L; Baumann, M; Surbek, D; Albrecht, C (2012). PP141. The lipid transporters ABCA1 and ABCG1 are differentially expressed in preeclamptic and IUGR placentas. Pregnancy hypertension, 2(3), pp. 315-316. Elsevier 10.1016/j.preghy.2012.04.252


Gertsch, Jürg; Viveros Paredes, Juan Manuel; Taylor, Peter (2011). Plant immunostimulants-Scientific paradigm or myth? Journal of ethnopharmacology, 136(3), pp. 385-391. Shannon: Elsevier Science Ireland 10.1016/j.jep.2010.06.044

Kovacs, Gergely; Danko, Tamas; Bergeron, Marc J; Balazs, Bernadett; Suzuki, Yoshiro; Zsembery, Akos; Hediger, Matthias A (2011). Heavy metal cations permeate the TRPV6 epithelial cation channel. Cell calcium, 49(1), pp. 43-55. Amsterdam: Elsevier 10.1016/j.ceca.2010.11.007

Landowski, Christopher P; Bolanz, Katrin A; Suzuki, Yoshiro; Hediger, Matthias A (2011). Chemical inhibitors of the calcium entry channel TRPV6. Pharmaceutical research, 28(2), pp. 322-30. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s11095-010-0249-9

Nikitina, L; Wenger, F; Baumann, M; Surbek, D; Körner, M; Albrecht, C (2011). Expression and localization pattern of ABCA1 in diverse human placental primary cells and tissues. Placenta, 32(6), pp. 420-30. Amsterdam: Elsevier 10.1016/j.placenta.2011.03.003

Mani, O; Körner, M; Ontsouka, C E; Sorensen, M T; Sejrsen, K; Bruckmaier, R M; Albrecht, C (2011). Identification of ABCA1 and ABCG1 in milk fat globules and mammary cells--implications for milk cholesterol secretion. Journal of dairy science, 94(3), pp. 1265-76. Savoy, Ill.: American Dairy Science Association 10.3168/jds.2010-3521

Lottaz, Daniel; Maurer, Christoph A; Noël, Agnès; Blacher, Silvia; Huguenin, Maya; Nievergelt, Alexandra; Niggli, Verena; Kern, Alexander; Müller, Stefan; Seibold, Frank; Friess, Helmut; Becker-Pauly, Christoph; Stöcker, Walter; Sterchi, Erwin E (2011). Enhanced activity of meprin-?, a pro-migratory and pro-angiogenic protease, in colorectal cancer. PLoS ONE, 6(11), e26450. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0026450

Patel, Dipesh C; Albrecht, Christiane; Pavitt, Darrell; Paul, Vijay; Pourreyron, Celine; Newman, Simon P; Godsland, Ian F; Valabhji, Jonathan; Johnston, Desmond G (2011). Type 2 diabetes is associated with reduced ATP-binding cassette transporter A1 gene expression, protein and function. PLoS ONE, 6(7), e22142. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0022142

Albrecht, Christiane; Nikitina, Liudmila; Wenger, Fabian Oliver; Baumann, Marc; Surbek, Daniel; Körner Jachertz, Meike (2011). ABCA1 and placental cholesterol efflux: a reply. Placenta, 32(9), pp. 710-711. Amsterdam: Elsevier 10.1016/j.placenta.2011.06.006

Greganova, Eva; Altmann, Michael; Bütikofer, Peter (2011). Unique modifications of translation elongation factors. FEBS journal, 278(15), pp. 2613-24. Oxford: Wiley-Blackwell 10.1111/j.1742-4658.2011.08199.x

Serricchio, Mauro; Bütikofer, Peter (2011). Trypanosoma brucei: a model micro-organism to study eukaryotic phospholipid biosynthesis. FEBS journal, 278(7), pp. 1035-46. Oxford: Wiley-Blackwell 10.1111/j.1742-4658.2011.08012.x

Jeckelmann, Jean-Marc; Harder, Daniel; Mari, Stefania A; Meury, Marcel; Ucurum, Zöhre; Müller, Daniel J; Erni, Bernhard; Fotiadis, Dimitrios (2011). Structure and function of the glucose PTS transporter from Escherichia coli. Journal of structural biology, 176(3), pp. 395-403. San Diego, Calif.: Elsevier 10.1016/j.jsb.2011.09.012

Bergeron, Marc J.; Boggavarapu, Rajendra; Meury, Marcel; Ucurum, Zöhre; Caron, Luc; Isenring, Paul; Hediger, Matthias A.; Fotiadis, Dimitrios (2011). Frog oocytes to unveil the structure and supramolecular organization of human transport proteins. PLoS ONE, 6(7), e21901. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0021901

Meury, Marcel; Harder, Daniel; Ucurum, Zöhre; Boggavarapu, Rajendra; Jeckelmann, Jean-Marc; Fotiadis, Dimitrios (2011). Structure determination of channel and transport proteins by high-resolution microscopy techniques. Biological chemistry, 392(1-2), pp. 143-50. Berlin: Walter de Gruyter 10.1515/BC.2011.004

Jeckelmann, Jean-Marc; Palacin, Manuel; Fotiadis, Dimitrios (2011). A tool for the qualitative comparison of membrane-embedded and detergent-solubilized membrane protein structures in projection. Journal of structural biology, 173(2), pp. 375-81. San Diego, Calif.: Elsevier 10.1016/j.jsb.2010.09.005

Ilgü, Hüseyin; Turan, Taylan; Şanli-Mohameda, Gülşa (2011). Immobilization and characterization of recombinant esterase enzyme on chitosan nanoparticles. Journal of macromolecular science. Part A - pure and applied chemistry, 48(9), pp. 713-721. Taylor & Francis 10.1080/10601325.2011.596050

Palanivelu, Dinesh V; Goepfert, Arnaud; Meury, Marcel; Guye, Patrick; Dehio, Christoph; Schirmer, Tilman (2011). Fic domain-catalyzed adenylylation: insight provided by the structural analysis of the type IV secretion system effector BepA. Protein science, 20(3), pp. 492-9. Malden, Mass.: Wiley-Blackwell 10.1002/pro.581

Sigel, Erwin; Baur, Roland; Rácz, Ildiko; Marazzi, Janine; Smart, Trevor G; Zimmer, Andreas; Gertsch, Jürg (2011). The major central endocannabinoid directly acts at GABA(A) receptors. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 108(44), pp. 18150-5. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.1113444108

Marazzi, Janine; Kleyer, Jonas; Paredes, Juan Manuel Viveros; Gertsch, Jürg (2011). Endocannabinoid content in fetal bovine sera - unexpected effects on mononuclear cells and osteoclastogenesis. Journal of immunological methods, 373(1-2), pp. 219-28. Amsterdam: Elsevier 10.1016/j.jim.2011.08.021

Nievergelt, Andreas; Marazzi, Janine; Schoop, Roland; Altmann, Karl-Heinz; Gertsch, Jürg (2011). Ginger phenylpropanoids inhibit IL-1beta and prostanoid secretion and disrupt arachidonate-phospholipid remodeling by targeting phospholipases A2. Journal of immunology, 187(8), pp. 4140-50. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.1100880

Schuehly, Wolfgang; Paredes, Juan Manuel Viveros; Kleyer, Jonas; Huefner, Antje; Anavi-Goffer, Sharon; Raduner, Stefan; Altmann, Karl-Heinz; Gertsch, Jürg (2011). Mechanisms of osteoclastogenesis inhibition by a novel class of biphenyl-type cannabinoid CB(2) receptor inverse agonists. Chemistry & biology, 18(8), pp. 1053-64. San Francisco, Calif.: Current Biology Ltd. 10.1016/j.chembiol.2011.05.012

Ritchie, M R; Gertsch, J; Klein, P; Schoop, R (2011). Effects of Echinaforce® treatment on ex vivo-stimulated blood cells. Phytomedicine, 18(10), pp. 826-31. Amsterdam: Elsevier 10.1016/j.phymed.2011.05.011

Maffei, Massimo E; Gertsch, Jürg; Appendino, Giovanni (2011). Plant volatiles: production, function and pharmacology. Natural product reports, 28(8), pp. 1359-80. Cambridge: Royal Society of Chemistry 10.1039/c1np00021g

Gertsch, Jürg (2011). Natural products in chemical biology. Current drug targets, 12(11), pp. 1513-4. Hilversum: Bentham Science Publishers 10.2174/138945011798109518

Ramesha, B T; Gertsch, Jürg; Ravikanth, G; Priti, V; Ganeshaiah, K N; Uma Shaanker, R (2011). Biodiversity and chemodiversity: future perspectives in bioprospecting. Current drug targets, 12(11), pp. 1515-30. Hilversum: Bentham Science Publishers

Zhang, Yuxun; Xie, Zhaojun; Wang, Lirong; Schreiter, Brielle; Lazo, John S; Gertsch, Jurg; Xie, Xiang-Qun (2011). Mutagenesis and computer modeling studies of a GPCR conserved residue W5.43(194) in ligand recognition and signal transduction for CB2 receptor. International immunopharmacology, 11(9), pp. 1303-10. Amsterdam: Elsevier 10.1016/j.intimp.2011.04.013

Gertsch, Jürg (2011). Botanical drugs, synergy, and network pharmacology: forth and back to intelligent mixtures. Planta medica, 77(11), pp. 1086-98. Stuttgart: Thieme 10.1055/s-0030-1270904

Schiess, Raphael; Gertsch, Jürg; Schweizer, W Bernd; Altmann, Karl-Heinz (2011). Stereoselective synthesis of 12,13-cyclopropyl-epothilone B and side-chain-modified variants. Organic letters, 13(6), pp. 1436-9. Washington, D.C.: American Chemical Society 10.1021/ol200114k

Bergeron, Marc J; Bürzle, Marc; Kovacs, Gergely; Simonin, Alexandre; Hediger, Matthias A (2011). Synthesis, maturation, and trafficking of human Na+-dicarboxylate cotransporter NaDC1 requires the chaperone activity of cyclophilin B. Journal of biological chemistry, 286(13), pp. 11242-53. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M110.171728

Sigel, Erwin; Lüscher, Benjamin P (2011). A closer look at the high affinity benzodiazepine binding site on GABAA receptors. Current topics in medicinal chemistry, 11(2), pp. 241-6. Hilversum: Bentham Science Publishers 10.2174/156802611794863562


Lis, Annette; Zierler, Susanna; Peinelt, Christine; Fleig, Andrea; Penner, Reinhold (2010). A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating. Journal of general physiology, 136(6), pp. 673-686. Rockefeller University Press 10.1085/jgp.201010484

Bogeski, Ivan; Al-Ansary, Dalia; Qu, Bin; Niemeyer, Barbara A; Hoth, Markus; Peinelt, Christine (2010). Pharmacology of ORAI channels as a tool to understand their physiological functions. Expert review of clinical pharmacology, 3(3), pp. 291-303. Taylor & Francis 10.1586/ecp.10.23

Bogeski, Ivan; Kummerow, Carsten; Al-Ansary, Dalia; Schwarz, Eva C; Koehler, Richard; Kozai, Daisuke; Takahashi, Nobuaki; Peinelt, Christine; Griesemer, Desiree; Bozem, Monika; Mori, Yasuo; Hoth, Markus; Niemeyer, Barbara A (2010). Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling. Science signaling, 3(115), ra24. American Association for the Advancement of Science 10.1126/scisignal.2000672

Ambort, Daniel; Brellier, Florence; Becker-Pauly, Christoph; Stöcker, Walter; Andrejevic-Blant, Snezana; Chiquet, Matthias; Sterchi, Erwin E (2010). Specific processing of tenascin-C by the metalloprotease meprinbeta neutralizes its inhibition of cell spreading. Matrix biology, 29(1), pp. 31-42. Amsterdam: Elsevier 10.1016/j.matbio.2009.08.007

Hofstetter, Willy; Siegrist, Mark; Simonin, Alexandre; Bonny, Olivier; Fuster, Daniel G (2010). Sodium/hydrogen exchanger NHA2 in osteoclasts: subcellular localization and role in vitro and in vivo. Bone, 47(2), pp. 331-340. New York, N.Y.: Elsevier 10.1016/j.bone.2010.04.605

Albrecht, C; Nikitina, L; Wenger, F; Baumann, M; Surbek, D; Körner, M (2010). Localisation of ABCA1 in first trimester and term placental tissues. Placenta, 31(8), pp. 741-2. Amsterdam: Elsevier 10.1016/j.placenta.2010.05.010

Mani, Orlando; Körner, Meike; Sorensen, Martin T; Sejrsen, Kristen; Wotzkow, Carlos; Ontsouka, Corneille E; Friis, Robert R; Bruckmaier, Rupert M; Albrecht, Christiane (2010). Expression, localization, and functional model of cholesterol transporters in lactating and nonlactating mammary tissues of murine, bovine, and human origin. American journal of physiology - regulatory, integrative and comparative physiology, 299(2), R642-54. Bethesda, Md.: American Physiological Society 10.1152/ajpregu.00723.2009

Simonin, Alexandre; Fuster, Daniel Guido (2010). Nedd4-1 and beta-arrestin-1 are key regulators of Na+/H+ exchanger 1 ubiquitylation, endocytosis, and function. Journal of biological chemistry, 285(49), pp. 38293-38303. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M110.115089

Steinke, K; Guertler, P; Paul, V; Wiedemann, S; Ettle, T; Albrecht, C; Meyer, H H D; Spiekers, H; Schwarz, F J (2010). Effects of long-term feeding of genetically modified corn (event MON810) on the performance of lactating dairy cows. Journal of animal physiology and animal nutrition, 94(5), e185-93. Berlin: Blackwell Science 10.1111/j.1439-0396.2010.01003.x

Ontsouka, C E; Burgener, I A; Mani, O; Albrecht, C (2010). Polyunsaturated fatty acid-enriched diets used for the treatment of canine chronic enteropathies decrease the abundance of selected genes of cholesterol homeostasis. Domestic animal endocrinology, 38(1), pp. 32-7. New York, N.Y.: Elsevier 10.1016/j.domaniend.2009.08.001

Guerteler, P; Paul, V; Steinke, K; Wiedemann, S; Preissinger, W; Albrecht, C; Spiekers, H; Schwarz, F.J.; Meyer, H.H.D. (2010). Long-term feeding of genetically modified corn (MON510)- Fate of cry1Ab DNA and recombinant protein during the metabolism of the dairy cow. Livestock science, 2010(131), pp. 250-259. Amsterdam: Elsevier 10.1016/j.livsci.2010.04.010

Altmann, Michael; Linder, Patrick (2010). Power of yeast for analysis of eukaryotic translation initiation. Journal of biological chemistry, 285(42), pp. 31907-12. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.R110.144196

Smith, Terry K; Bütikofer, Peter (2010). Lipid metabolism in Trypanosoma brucei. Molecular and biochemical parasitology, 172(2), pp. 66-79. Amsterdam: Elsevier 10.1016/j.molbiopara.2010.04.001

Xue, Gondga; von Schubert, Conrad; Hermann, Pascal; Peyer, Martina; Maushagen, Regina; Schmuckli-Maurer, Jacqueline; Bütikofer, Peter; Langsley, Gordon; Dobbelaere, Dirk, (2010). Characterisation of gp34, a GPI-anchored protein expressed by schizonts of Theileria parva and T. annulata. Molecular and biochemical parasitology, 172(2), pp. 113-20. Amsterdam: Elsevier 10.1016/j.molbiopara.2010.03.018

Bütikofer, Peter; Greganova, Eva; Liu, Yuk-Chien; Edwards, Ian J; Lehane, Michael J; Acosta-Serrano, Alvaro (2010). Lipid remodelling of glycosylphosphatidylinositol (GPI) glycoconjugates in procyclic-form trypanosomes: biosynthesis and processing of GPIs revisited. Biochemical journal, 428(3), pp. 409-18. London: Portland Press 10.1042/BJ20100229

Greganova, E; Buetikofer, P; Acosta Serrano, A (2010). The lipid portion of protease resistant surface glycoconjugate from Trypanosoma congolense is composed of triacylated phosphatidylinositol lipids and contains myristate. Molecular and biochemical parasitology, 2010(171), pp. 50-54. Amsterdam: Elsevier

Kronenberg, Daniel; Bruns, Bernd C; Moali, Catherine; Vadon-Le Goff, Sandrine; Sterchi, Erwin E; Traupe, Heiko; Böhm, Markus; Hulmes, David J S; Stöcker, Walter; Becker-Pauly, Christoph (2010). Processing of procollagen III by meprins: new players in extracellular matrix assembly? Journal of Investigative Dermatology, 130(12), pp. 2727-35. New York, N.Y.: Nature Publishing 10.1038/jid.2010.202

Bruning, M; Kreplak, L; Leopoldseder, S; Müller, SA; Tingler, P; Duchesne, L; Ferning, DG; Engel, A; Ucurum-Fotiadis, Z; Mayans, O (2010). Biparte Design of a Self-Fibrillating Protein Copolymer with Nanopatterned Peptide Display Capabilites. Nano letters, 10(11)(Nov 2010), pp. 4533-4537. Washington, D.C.: American Chemical Society 10.1021/nl1024886

Dutzler, Raimund; Ernstb, Beat; Hediger, Matthias A; Keppler, Dietrich; Mohr, Peter; Neidhart, Werner; Märki, Hans Peter (2010). Channels and transporters. Mini-symposium of the Division of Medicinal Chemistry (DMC) of the Swiss Chemical Society (SCS) at the Department of Chemistry, University of Basel, May 27, 2010. CHIMIA, 64(9), pp. 662-6. Bern: Schweizerische Chemische Gesellschaft

Luethi, Erika; Nguyen, Kong T; Bürzle, Marc; Blum, Lorenz C; Suzuki, Yoshiro; Hediger, Matthias; Reymond, Jean-Louis (2010). Identification of selective norbornane-type aspartate analogue inhibitors of the glutamate transporter 1 (GLT-1) from the chemical universe generated database (GDB). Journal of medicinal chemistry, 53(19), pp. 7236-50. Easton, Pa.: American Chemical Society 10.1021/jm100959g

Lieben, L; Benn, B S; Ajibade, D; Stockmans, I; Moermans, K; Hediger, M A; Peng, J B; Christakos, S; Bouillon, R; Carmeliet, G (2010). Trpv6 mediates intestinal calcium absorption during calcium restriction and contributes to bone homeostasis. Bone, 47(2), pp. 301-8. New York, N.Y.: Elsevier 10.1016/j.bone.2010.04.595

Baur, Roland; Lüscher, Benjamin P; Richter, Lars; Sigel, Erwin (2010). A residue close to ?1 loop F disrupts modulation of GABAA receptors by benzodiazepines while their binding is maintained. Journal of neurochemistry, 115(6), pp. 1478-85. Oxford: Wiley-Blackwell 10.1111/j.1471-4159.2010.07052.x

Rufener, Lucien; Baur, Roland; Kaminsky, Ronald; Mäser, Pascal; Sigel, Erwin (2010). Monepantel allosterically activates DEG-3/DES-2 channels of the gastrointestinal nematode Haemonchus contortus. Molecular pharmacology, 78(5), pp. 895-902. Bethesda, Md.: American Society for Pharmacology and Experimental Therapeutics 10.1124/mol.110.066498

Baur, Roland; Kaur, Kuldeep H; Sigel, Erwin (2010). Diversity of structure and function of alpha1alpha6beta3delta GABAA receptors: comparison with alpha1beta3delta and alpha6beta3delta receptors. Journal of biological chemistry, 285(23), pp. 17398-405. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M110.108670

Kopp, Sascha; Baur, Roland; Sigel, Erwin; Möhler, Hanns; Altmann, Karl-Heinz (2010). Highly potent modulation of GABA(A) receptors by valerenic acid derivatives. ChemMedChem, 5(5), pp. 678-81. Weinheim: Wiley-VCH 10.1002/cmdc.201000062

Minier, F; Sigel, E (2010). Ligand-Operated Membrane Channels:GABA. In: Elsevier, Oxford (ed.) Encyclopedia of Biological Chemistry (W.J. Lennarz and M.C.Lade, eds). Amsterdam: Elsevier

Sigel, E (2010). Microinjection into Xenopus oocytes. In: Encyclopedia of Life Sciences. Chichester: John Wiley & Sons Ltd 10.1002/9780470015902.a0002658.pub2

Dietrich, Silvia Anthoine; Riediker, Linda; Gertsch, Jürg; Altmann, Karl-Heinz (2010). Synthesis and biological activity of new functionalized epothilones for prodrug design and tumor targeting. CHIMIA, 64(3), pp. 136-9. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2010.136

Altmann, Karl-Heinz; Cachoux, Frédéric; Feyen, Fabian; Gertsch, Jürg; Kuzniewski, Christian N; Wartmann, Markus (2010). Natural products as leads for anticancer drug discovery: discovery of new chemotypes of microtubule stabilizers through reengineering of the epothilone scaffold. CHIMIA, 64(1-2), pp. 8-13. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2010.8

Gertsch, Jürg; Pertwee, Roger G; Di Marzo, Vincenzo (2010). Phytocannabinoids beyond the Cannabis plant - do they exist? British journal of pharmacology, 160(3), pp. 523-9. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2010.00745.x

De Simone, Filippo; Gertsch, Jürg; Waser, Jérôme (2010). Catalytic selective cyclizations of aminocyclopropanes: formal synthesis of aspidospermidine and total synthesis of goniomitine. Angewandte Chemie (International ed.), 49(33), pp. 5767-70. Weinheim: Wiley-VCH 10.1002/anie.201001853

Leonti, Marco; Casu, Laura; Solinas, Maria Novella; Cottiglia, Filippo; Caboni, Pierluigi; Floris, Costantino; Gertsch, Juerg; Saba, Anna Rita (2010). A chromone from Seseli praecox (Apiaceae). Natural product communications, 5(4), pp. 551-4. Westerville, Ohio: Natural Product Communications NPC

Erdélyi, Máté; Navarro-Vázquez, Armando; Pfeiffer, Bernhard; Kuzniewski, Christian N; Felser, Andrea; Widmer, Toni; Gertsch, Jürg; Pera, Benet; Díaz, José Fernando; Altmann, Karl-Heinz; Carlomagno, Teresa (2010). The binding mode of side chain- and C3-modified epothilones to tubulin. ChemMedChem, 5(6), pp. 911-920. Weinheim: Wiley-VCH 10.1002/cmdc.201000050

Zurwerra, Didier; Gertsch, Jürg; Altmann, Karl-Heinz (2010). Synthesis of (-)-dactylolide and 13-desmethylene-(-)-dactylolide and their effects on tubulin. Organic letters, 12(10), pp. 2302-5. Washington, D.C.: American Chemical Society 10.1021/ol100665m

Nievergelt, Andreas; Huonker, Peter; Schoop, Roland; Altmann, Karl-Heinz; Gertsch, Jürg (2010). Identification of serotonin 5-HT1A receptor partial agonists in ginger. Bioorganic & medicinal chemistry, 18(9), pp. 3345-51. Amsterdam: Elsevier 10.1016/j.bmc.2010.02.062

Leonti, Marco; Casu, Laura; Gertsch, Jürg; Bonsignore, Leonardo; Floris, Costantino; Casu, Mariano; Cottiglia, Filippo (2010). A pterocarpan from the seeds of Bituminaria morisiana. Journal of natural medicines, 64(3), pp. 354-7. Tōkyō: Springer 10.1007/s11418-010-0408-7

Shwe, Htay Htay; Aye, Mye; Sein, Myint Myint; Htay, Khin Than; Kreitmeier, Peter; Gertsch, Jürg; Reiser, Oliver; Heilmann, Jörg (2010). Cytotoxic steroidal saponins from the rhizomes of Tacca integrifolia. Chemistry & Biodiversity, 7(3), pp. 610-22. Zürich: Verlag Helvetica Chimica Acta

Leonti, Marco; Casu, Laura; Raduner, Stefan; Cottiglia, Filippo; Floris, Costantino; Altmann, Karl-Heinz; Gertsch, Jürg (2010). Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin. Biochemical pharmacology, 79(12), pp. 1815-26. New York, N.Y.: Elsevier 10.1016/j.bcp.2010.02.015

Wullschleger, Christoph W; Gertsch, Jürg; Altmann, Karl-Heinz (2010). Stereoselective synthesis of a monocyclic peloruside a analogue. Organic letters, 12(5), pp. 1120-3. Washington, D.C.: American Chemical Society 10.1021/ol100123p

Peng, Jiangnan; Kudrimoti, Sucheta; Prasanna, Sivaprakasam; Odde, Srinivas; Doerksen, Robert J; Pennaka, Hari K; Choo, Yeun-Mun; Rao, Karumanchi V; Tekwani, Babu L; Madgula, Vamsi; Khan, Shabana I; Wang, Bin; Mayer, Alejandro M S; Jacob, Melissa R; Tu, Lan Chun; Gertsch, Jürg; Hamann, Mark T (2010). Structure-activity relationship and mechanism of action studies of manzamine analogues for the control of neuroinflammation and cerebral infections. Journal of medicinal chemistry, 53(1), pp. 61-76. Easton, Pa.: American Chemical Society

Greganova, E; Heller, M; Bütikofer, P (2010). A structural domain mediates attachment of ethanolamine phosphoglycerol to eukaryotic elongation factor 1A in Trypanosoma brucei. PLoS ONE, 5(3), e9486. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0009486

Kempna, Petra; Ricciarelli, Roberta; Azzi, Angelo; Zingg, Jean-Marc (2010). Alternative splicing and gene polymorphism of the human TAP3/SEC14L4 gene. Molecular biology reports, 37(7), pp. 3503-3508. Springer 10.1007/s11033-009-9943-2


Peinelt, Christine; Beck, Andreas; Monteilh-Zoller, Mahealani K; Penner, Reinhold; Fleig, Andrea (2009). IP(3) receptor subtype-dependent activation of store-operated calcium entry through I(CRAC). Cell calcium, 45(4), pp. 326-330. Elsevier 10.1016/j.ceca.2008.12.001

Wiedemann, S; Lutz, B; Albrecht, C; Kuehn, R; Killermann, B; Einspanier, R; Meyer, H.H.D. (2009). Fate of genetically modified maize and conventional rapeseed, and endozoochory in wild boar (Sus scrofa). Mammalian biology, 3(74), pp. 191-197. München: Elsevier 10.1016/j.mambio.2008.07.002

Shedova, E; Albrecht, C; Zverlov, V.V.; Schwarz, W.H. (2009). Stimulation of bacterial DNA transformation by cattle saliva: implications for using genetically modified plants in animal feed. World journal of microbiology & biotechnology, 3(25), 457-463 [7 page(s) (article)] (3/4 p.). Oxford: Springer 10.1007/s11274-008-9910-4

Gertsch, Jürg; Meier, Sarah; Müller, Martin; Altmann, Karl-Heinz (2009). Differential effects of natural product microtubule stabilizers on microtubule assembly: single agent and combination studies with taxol, epothilone B, and discodermolide. ChemBioChem, 10(1), pp. 166-75. Weinheim: Wiley-VCH 10.1002/cbic.200800556

Banerjee, S; Oneda, B; Yap, L M; Jewell, D P; Matters, G L; Fitzpatrick, L R; Seibold, F; Sterchi, E E; Ahmad, T; Lottaz, D; Bond, J S (2009). MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease. Mucosal immunology, 2(3), pp. 220-31. New York, N.Y.: Nature Publishing Group 10.1038/mi.2009.3

Signorell, Aita; Gluenz, Eva; Rettig, Jochen; Schneider, André; Shaw, Michael; Gull, Keith; Bütikofer, Peter (2009). Perturbation of phosphatidylethanolamine synthesis affects mitochondrial morphology and cell-cycle progression in procyclic-form Trypanosoma brucei. Molecular microbiology, 72(4), pp. 1068-79. Oxford: Blackwell Science 10.1111/j.1365-2958.2009.06713.x

Vassella, Erik; Oberle, Michael; Urwyler, Simon; Renggli, Christina Kunz; Studer, Erwin; Hemphill, Andrew; Fragoso, Cristina; Bütikofer, Peter; Brun, Reto; Roditi, Isabel (2009). Major surface glycoproteins of insect forms of Trypanosoma brucei are not essential for cyclical transmission by tsetse. PLoS ONE, 4(2), e4493. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0004493

Passarella, Daniele; Comi, Daniela; Cappelletti, Graziella; Cartelli, Daniele; Gertsch, Juerg; Quesada, Ana R; Borlak, Jurgen; Altmann, Karl-Heinz (2009). Synthesis and biological evaluation of epothilone A dimeric compounds. Bioorganic & medicinal chemistry, 17(21), pp. 7435-40. Amsterdam: Elsevier 10.1016/j.bmc.2009.09.032

Dietrich, Silvia Anthoine; Lindauer, Renate; Stierlin, Claire; Gertsch, Jürg; Matesanz, Ruth; Notararigo, Sara; Díaz, José Fernando; Altmann, Karl-Heinz (2009). Epothilone analogues with benzimidazole and quinoline side chains: chemical synthesis, antiproliferative activity, and interactions with tubulin. Chemistry - a European journal, 15(39), pp. 10144-57. Weinheim: Wiley-VCH 10.1002/chem.200901376

Oesch, Susanne; Gertsch, Jürg (2009). Cannabinoid receptor ligands as potential anticancer agents--high hopes for new therapies? Journal of pharmacy and pharmacology, 61(7), pp. 839-53. London: Royal Pharmaceutical Society of Great Britain 10.1211/jpp/61.07.0002

Pfeiffer, Bernhard; Hauenstein, Kurt; Merz, Philipp; Gertsch, Jürg; Altmann, Karl-Heinz (2009). Synthesis and SAR of C12-C13-oxazoline derivatives of epothilone A. Bioorganic and medicinal chemistry letters, 19(14), pp. 3760-3. New York, N.Y.: Pergamon 10.1016/j.bmcl.2009.04.112

Gollner, Andreas; Altmann, Karl-Heinz; Gertsch, Jürg; Mulzer, Johann (2009). The laulimalide family: total synthesis and biological evaluation of neolaulimalide, isolaulimalide, laulimalide and a nonnatural analogue. Chemistry - a European journal, 15(24), pp. 5979-97. Weinheim: Wiley-VCH 10.1002/chem.200802605

Chicca, Andrea; Raduner, Stefan; Pellati, Federica; Strompen, Thomas; Altmann, Karl-Heinz; Schoop, Roland; Gertsch, Jürg (2009). Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts. International immunopharmacology, 9(7-8), pp. 850-8. Amsterdam: Elsevier 10.1016/j.intimp.2009.03.006

Gertsch, Jürg (2009). How scientific is the science in ethnopharmacology? Historical perspectives and epistemological problems. Journal of ethnopharmacology, 122(2), pp. 177-83. Shannon: Elsevier Science Ireland 10.1016/j.jep.2009.01.010

Markt, Patrick; Feldmann, Clemens; Rollinger, Judith Maria; Raduner, Stefan; Schuster, Daniela; Kirchmair, Johannes; Distinto, Simona; Spitzer, Gudrun Maria; Wolber, Gerhard; Laggner, Christian; Altmann, Karl-Heinz; Langer, Thierry; Gertsch, Jürg (2009). Discovery of novel CB2 receptor ligands by a pharmacophore-based virtual screening workflow. Journal of medicinal chemistry, 52(2), pp. 369-78. Easton, Pa.: American Chemical Society 10.1021/jm801044g

Rollinger, Judith M; Schuster, Daniela; Danzl, Birgit; Schwaiger, Stefan; Markt, Patrick; Schmidtke, Michaela; Gertsch, Jürg; Raduner, Stefan; Wolber, Gerhard; Langer, Thierry; Stuppner, Hermann (2009). In silico target fishing for rationalized ligand discovery exemplified on constituents of Ruta graveolens. Planta medica, 75(3), pp. 195-204. Stuttgart: Thieme 10.1055/s-0028-1088397

Gertsch, Jürg; Feyen, Fabian; Bützberger, Alexander; Gerber, Barbara; Pfeiffer, Bernhard; Altmann, Karl-Heinz (2009). Making epothilones fluoresce: design, synthesis, and biological characterization of a fluorescent N12-aza-epothilone (azathilone). ChemBioChem, 10(15), pp. 2513-21. Weinheim: Wiley-VCH 10.1002/cbic.200900376

Casagrande, Fabio; Harder, Daniel; Schenk, Andreas; Meury, Marcel; Ucurum, Zohre; Engel, Andreas; Weitz, Dietmar; Daniel, Hannelore; Fotiadis, Dimitrios (2009). Projection structure of DtpD (YbgH), a prokaryotic member of the peptide transporter family. Journal of molecular biology, 394(4), pp. 708-17. Amsterdam: Elsevier 10.1016/j.jmb.2009.09.048

Bippes, Christian A; Zeltina, Antra; Casagrande, Fabio; Ratera, Merce; Palacin, Manuel; Muller, Daniel J; Fotiadis, Dimitrios (2009). Substrate binding tunes conformational flexibility and kinetic stability of an amino acid antiporter. Journal of biological chemistry, 284(28), pp. 18651-63. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M109.004267

Jastrzebska, Beata; Golczak, Marcin; Fotiadis, Dimitrios; Engel, Andreas; Palczewski, Krzysztof (2009). Isolation and functional characterization of a stable complex between photoactivated rhodopsin and the G protein, transducin. FASEB journal, 23(2), pp. 371-81. Bethesda, Md.: Federation of American Societies for Experimental Biology 10.1096/fj.07-114835

Bolanz, Katrin A; Kovacs, Gergely Gy; Landowski, Christopher P; Hediger, Matthias A (2009). Tamoxifen inhibits TRPV6 activity via estrogen receptor-independent pathways in TRPV6-expressing MCF-7 breast cancer cells. Molecular cancer research, 7(12), pp. 2000-10. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1541-7786.MCR-09-0188

Sigel, Erwin; Kaur, Kuldeep H; Lüscher, Benjamin P; Baur, Roland (2009). Use of concatamers to study GABAA receptor architecture and function: application to delta-subunit-containing receptors and possible pitfalls. Biochemical Society transactions, 37(Pt 6), pp. 1338-42. London: Portland Press 10.1042/BST0371338

Tan, Kelly R; Baur, Roland; Charon, Sébastien; Goeldner, Maurice; Sigel, Erwin (2009). Relative positioning of diazepam in the benzodiazepine-binding-pocket of GABA receptors. Journal of neurochemistry, 111(5), pp. 1264-73. Oxford: Wiley-Blackwell 10.1111/j.1471-4159.2009.06419.x

Baur, Roland; Kaur, Kuldeep H; Sigel, Erwin (2009). Structure of alpha6 beta3 delta GABA(A) receptors and their lack of ethanol sensitivity. Journal of neurochemistry, 111(5), pp. 1172-81. Oxford: Wiley-Blackwell 10.1111/j.1471-4159.2009.06387.x

Kaur, Kuldeep H; Baur, Roland; Sigel, Erwin (2009). Unanticipated structural and functional properties of delta-subunit-containing GABAA receptors. Journal of biological chemistry, 284(12), pp. 7889-96. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M806484200

Nichols, Buford L; Quezada-Calvillo, Roberto; Robayo-Torres, Claudia C; Ao, Zihua; Hamaker, Bruce R; Butte, Nancy F; Marini, Juan; Jahoor, Farook; Sterchi, Erwin E (2009). Mucosal maltase-glucoamylase plays a crucial role in starch digestion and prandial glucose homeostasis of mice. Journal of nutrition, 139(4), pp. 684-90. Bethesda, Md.: American Society for Nutrition 10.3945/jn.108.098434

Bergeron, Marc J; Frenette-Cotton, Rachelle; Carpentier, Gabriel A; Simard, Michael G; Caron, Luc; Isenring, Paul (2009). Phosphoregulation of K(+)-Cl(-) cotransporter 4 during changes in intracellular Cl(-) and cell volume. Journal of cellular physiology, 219(3), pp. 787-96. Hoboken, N.J.: Wiley 10.1002/jcp.21725

Wächter, Regula; Masarik, Lukas; Bürzle, Marc; Mallik, Ajit; von Mandach, Ursula (2009). Differential expression and activity of 11beta-hydroxysteroid dehydrogenase in human placenta and fetal membranes from pregnancies with intrauterine growth restriction. Fetal diagnosis and therapy, 25(3), pp. 328-35. Basel: Karger 10.1159/000235879

Gollner, A; Altmann, K.-H; Gertsch, J; Mulzer, J (2009). Synthesis and biological evaluation of a des-dihydropyran laulimalide analog. Tetrahedron letters, 50(42), pp. 5790-5792. Amsterdam: Elsevier 10.1016/j.tetlet.2009.07.122

Guertler, Patrick; Paul, Vijay; Albrecht, Christiane; Meyer, Heinrich H D (2009). Sensitive and highly specific quantitative real-time PCR and ELISA for recording a potential transfer of novel DNA and Cry1Ab protein from feed into bovine milk. Analytical and bioanalytical chemistry, 393(6-7), pp. 1629-38. Heidelberg: Springer 10.1007/s00216-009-2667-2

Mani, O; Sorensen, M T; Sejrsen, K; Bruckmaier, R M; Albrecht, C (2009). Differential expression and localization of lipid transporters in the bovine mammary gland during the pregnancy-lactation cycle. Journal of dairy science, 92(8), pp. 3744-56. Savoy, Ill.: American Dairy Science Association 10.3168/jds.2009-2063


Peinelt, Christine; Lis, Annette; Beck, Andreas; Fleig, Andrea; Penner, Reinhold (2008). 2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels. Journal of physiology, 586(13), pp. 3061-3073. Wiley-Blackwell 10.1113/jphysiol.2008.151365

Parvez, Suhel; Beck, Andreas; Peinelt, Christine; Soboloff, Jonathan; Lis, Annette; Monteilh-Zoller, Mahealani; Gill, Donald L; Fleig, Andrea; Penner, Reinhold (2008). STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation. FASEB journal, 22(3), pp. 752-761. Federation of American Societies for Experimental Biology 10.1096/fj.07-9449com

Bollan, Karen A; Baur, Roland; Hales, Tim G; Sigel, Erwin; Connolly, Christopher N (2008). The promiscuous role of the epsilon subunit in GABA(A) receptor biogenesis. Molecular and cellular neuroscience, 37(3), pp. 610-621. San Diego, Calif.: Elsevier 10.1016/j.mcn.2007.12.011

Niggli, Verena; Sigel, Erwin (2008). Anticipating antiport in P-type ATPases. Trends in biochemical sciences, 33(4), pp. 156-60. Cambridge: Elsevier Current Trends 10.1016/j.tibs.2007.12.005

Farke, Carolin; Meyer, Heinrich H D; Bruckmaier, Rupert M; Albrecht, Christiane (2008). Differential expression of ABC transporters and their regulatory genes during lactation and dry period in bovine mammary tissue. Journal of dairy research, 75(4), pp. 406-14. London: Cambridge University Press 10.1017/S002202990800335X

Paul, Vijay; Meyer Heinrich, H D; Leidl, Katharina; Soumian, Soni; Albrecht, Christiane (2008). A novel enzyme immunoassay specific for ABCA1 protein quantification in human tissues and cells. Journal of lipid research, 49(10), pp. 2259-67. Bethesda, Md.: American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.D700040-JLR200

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Casagrande, Fabio; Ratera, Merce; Schenk, Andreas D; Chami, Mohamed; Valencia, Eva; Lopez, Jesus Maria; Torrents, David; Engel, Andreas; Palacin, Manuel; Fotiadis, Dimitrios (2008). Projection structure of a member of the amino acid/polyamine/organocation transporter superfamily. Journal of biological chemistry, 283(48), pp. 33240-8. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M806917200

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