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Dhayat, Nasser A.; Lüthi, David; Schneider, Lisa; Mattmann, Cedric; Vogt, Bruno; Fuster, Daniel Guido (2019). Dinstinct phenotype of kidney stone formers with renal phosphate leak. Nephrology, dialysis, transplantation, 34(1), pp. 129-137. Oxford University Press 10.1093/ndt/gfy170

Bulla, M.; Gyimesi, Gergely; Kim, JH.; Bhardwaj, Rajesh; Hediger, Matthias; Frieden, M.; Demaurex, N. (2019). ORAI1 channel gating and selectivity is differentially altered by natural mutations in the first or third transmembrane domain. Journal of physiology, 597(2), pp. 561-582. Wiley-Blackwell 10.1113/JP277079


Poirier, Marion; Awale, Mahendra; Rölli, Matthias A.; Giuffredi, Guy T.; Ruddigkeit, Lars; Evensen, Lasse; Stooss, Amandine; Calarco, Serafina; Lorens, James B.; Charles, Roch-Philippe; Reymond, Jean-Louis (2018). Identifying Lysophosphatidic Acid Acyltransferase β (LPAAT-β) as the Target of a Nanomolar Angiogenesis Inhibitor from a Phenotypic Screen Using the Polypharmacology Browser PPB2 (In Press). ChemMedChem, 13, pp. 1-14. Wiley-VCH 10.1002/cmdc.201800554

Schröck, Alexandra; Henzi, Anna; Bütikofer, Peter; König, Stefan; Weinmann, Wolfgang (2018). Determination of the formation rate of phosphatidylethanol by phospholipase D (PLD) in blood and test of two selective PLD inhibitors. Alcohol, 73, pp. 1-7. Elsevier 10.1016/j.alcohol.2018.03.003

El Mokh, Oussama; Taelmann, Vincent; Radojewski, Piotr; Rölli, Matthias Andreas; Stooss, Amandine; Dumont, Rebecca A; Dettmer, Matthias; Phillips, Wayne; Walter, Martin Alexander; Charles, Roch-Philippe (2018). MEK inhibition induces therapeutic iodine uptake in a murine model of anaplastic thyroid cancer. (In Press). Journal of nuclear medicine Society of Nuclear Medicine 10.2967/jnumed.118.216721

Kandasamy, Palanivel; Gyimesi, Gergely; Kanai, Yoshikatsu; Hediger, Matthias (2018). Amino acid transporters revisited: New views in health and disease. Trends in biochemical sciences, 43(10), pp. 752-789. Elsevier Current Trends 10.1016/j.tibs.2018.05.003

Häfliger, Pascal; Graff, Julien; Rubin, Matthias; Stooss, Amandine; Dettmer, Matthias S.; Altmann, Karl-Heinz; Gertsch, Jürg; Charles, Roch-Philippe (2018). The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model. Journal of experimental & clinical cancer research, 37(1), p. 234. BioMed Central 10.1186/s13046-018-0907-z

Tamò, Luca; Hibaoui, Youssef; Kallol, Sampada; Alves, Marco P.; Albrecht, Christiane; Hostettler, Katrin E; Feki, Anis; Rougier, Jean-Sébastien; Abriel, Hugues; Knudsen, Lars; Gazdhar, Amiq; Geiser, Thomas (2018). Generation of an alveolar epithelial type II cell line from induced pluripotent stem cells. (In Press). American journal of physiology - lung cellular and molecular physiology American Physiological Society 10.1152/ajplung.00357.2017

Jack, Thomas; Leuenberger, Michele; Ruepp, Marc-David; Vernekar, Sanjeev Kumar V; Thompson, Andrew James; Braga-Lagache, Sophie; Heller, Manfred; Lochner, Martin (2018). Mapping the Orthosteric Binding Site of the Human 5-HT3 Receptor Using Photo-crosslinking Antagonists (In Press). ACS chemical neuroscience American Chemical Society 10.1021/acschemneuro.8b00327

Liu, He; He, Zhaoyue; April, Simon Leonhard; Trefny, Marcel Philipp; Rougier, Jean-Sébastien; Salemi, Souzan; Olariu, Radu; Widmer, Hans Rudolf; Simon, Hans-Uwe (2018). Biochemical re-programming of human dermal stem cells to neurons by increasing mitochondrial membrane potential. (In Press). Cell death and differentiation Nature Publishing Group 10.1038/s41418-018-0182-8

Zákány, Nóra; Oláh, Attila; Markovics, Arnold; Takács, Erika; Aranyász, Andrea; Nicolussi, Simon; Piscitelli, Fabiana; Allarà, Marco; Pór, Ágnes; Kovács, Ilona; Zouboulis, Christos C; Gertsch, Jürg; Di Marzo, Vincenzo; Bíró, Tamás; Szabó, Tamás (2018). Endocannabinoid Tone Regulates Human Sebocyte Biology. Journal of Investigative Dermatology, 138(8), pp. 1699-1706. Nature Publishing 10.1016/j.jid.2018.02.022

Franz, Marie-Christine; Pujol Gimenez, Jonai; Montalbetti, Nicolas; Fernandez Tenorio, Miguel; DeGrado, Timothy R.; Niggli, Ernst; Romero, Michael F.; Hediger, Matthias (2018). Reassessment of the transport mechanism of the human zinc transporter SLC39A2. Biochemistry, 57(26), pp. 3976-3986. American Chemical Society 10.1021/acs.biochem.8b00511

Fuster, Daniel G.; Moe, Orson W (2018). Incomplete Distal Renal Tubular Acidosis and Kidney Stones. Advances in chronic kidney disease, 25(4), pp. 366-374. Elsevier 10.1053/j.ackd.2018.05.007

Ozhathil, Lijo Cherian; Delalande, Clémence Marie Sandrine; Bianchi, Beatrice; Nemeth, Gabor; Kappel, Sven; Thomet, Urs; Ross, Daniela; Simonin, Céline; Rubin, Matthias; Gertsch, Jürg; Lochner, Martin; Peinelt, Christine; Reymond, Jean-Louis; Abriel, Hugues (2018). Identification of potent and selective small molecule inhibitors of the cation channel TRPM4. British journal of pharmacology, 175(12), pp. 2504-2519. Wiley-Blackwell 10.1111/bph.14220

Arndt, Nick; Ross-Kaschitza, Daniela; Kojukhov, Artyom; Komar, Anton A.; Altmann, Michael (2018). Properties of the ternary complex formed by yeast eIF4E, p20 and mRNA. Scientific Reports, 8(1), p. 6707. Nature Publishing Group 10.1038/s41598-018-25273-3

Schroeder, Mariana; Jakovcevski, Mira; Polacheck, Tamar; Drori, Yonat; Luoni, Alessia; Röh, Simone; Zaugg, Jonas; Ben-Dor, Shifra; Albrecht, Christiane; Chen, Alon (2018). Placental miR-340 mediates vulnerability to activity based anorexia in mice. Nature communications, 9(1), p. 1596. Nature Publishing Group 10.1038/s41467-018-03836-2

Clemençon, Benjamin; Lüscher, Benjamin; Hediger, Matthias (2018). Establishment of a novel microscale thermophoresis ligand-binding assay for characterization of SLC solute carriers using oligopeptide transporter PepT1 (SLC15 family) as a model system. Journal of pharmacological and toxicological methods, 92, pp. 67-76. Elsevier 10.1016/j.vascn.2018.03.004

Huang, Xiao; Anderle, Pascale; Hostettler, Lu; Baumann, Marc Ulrich; Surbek, Daniel; Ontsouka, Edgar; Albrecht, Christiane (2018). Identification of placental nutrient transporters associated with intrauterine growth restriction and pre-eclampsia. BMC Genomics, 19(1), p. 173. BioMed Central 10.1186/s12864-018-4518-z

Schmidt, Remo S.; Pereira de Macêdo, Juan; Steinmann, Michael Eduard; González Salgado, Amaia; Bütikofer, Peter; Sigel, Erwin; Rentsch, Doris; Mäser, Pascal (2018). Transporters of Trypanosoma brucei -phylogeny, physiology, pharmacology. FEBS journal, 285(6), pp. 1012-1023. Wiley 10.1111/febs.14302

Gertsch, Jürg (2018). Analytical and Pharmacological Challenges in Cannabis Research. Planta medica, 84(4), p. 213. Thieme 10.1055/s-0044-101051

Pathare, Ganesh Tukaram; Anderegg, Manuel; Albano, Giuseppe; Lang, Florian; Fuster, Daniel Guido (2018). Elevated FGF23 Levels in Mice Lacking the Thiazide-Sensitive NaCl cotransporter (NCC). Scientific Reports, 8(1), p. 3590. Nature Publishing Group 10.1038/s41598-018-22041-1

Hichri, Echrak; Abriel, Hugues; Kucera, Jan (2018). Distribution of cardiac sodium channels in clusters potentiates ephaptic interactions in the intercalated disc. Journal of physiology, 596(4), pp. 563-589. Wiley-Blackwell 10.1113/JP275351

Aghazadeh Tabrizi, Mojgan; Baraldi, Pier Giovanni; Baraldi, Stefania; Ruggiero, Emanuela; De Stefano, Lucia; Rizzolio, Flavio; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Chicca, Andrea; Lapillo, Margherita; Gertsch, Jürg; Manera, Clementina; Macchia, Marco; Martinelli, Adriano; Granchi, Carlotta; Minutolo, Filippo; Tuccinardi, Tiziano (2018). Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors. Journal of medicinal chemistry, 61(3), pp. 1340-1354. American Chemical Society 10.1021/acs.jmedchem.7b01845

Pathare, Ganesh Tukaram; Dhayat, Nasser; Mohebbi, Nilufar; Wagner, Carsten A.; Cheval, Lydie; Neuhaus, Thomas J.; Fuster, Daniel Guido (2018). Acute regulated expression of pendrin in human urinary exosomes. Pflügers Archiv : European journal of physiology, 470(2), pp. 427-438. Springer 10.1007/s00424-017-2049-0

Varga, Zoltan V; Matyas, Csaba; Erdelyi, Katalin; Cinar, Resat; Nieri, Daniela; Chicca, Andrea; Nemeth, Balazs Tamas; Paloczi, Janos; Lajtos, Tamas; Corey, Lukas; Hasko, Gyorgy; Gao, Bin; Kunos, George; Gertsch, Jürg; Pacher, Pal (2018). Beta-caryophyllene protects against alcoholic steatohepatitis by attenuating inflammation and metabolic dysregulation in mice. British journal of pharmacology, 175(2), pp. 320-334. Wiley-Blackwell 10.1111/bph.13722

Pathare, Ganesh Tukaram; Dhayat, Nasser; Mohebbi, Nilufar; Wagner, Carsten A.; Bobulescu, Alexandru; Moe, Orson W.; Fuster, Daniel Guido (2018). Changes in V-ATPase subunits of human urinary exosomes reflect the renal response to acute acid/alkali loading and the defects in distal renal tubular acidosis. Kidney international, 93(4), pp. 871-880. Elsevier 10.1016/j.kint.2017.10.018

Alexander, R Todd; McArthur, Eric; Jandoc, Racquel; Welk, Blayne; Fuster, Daniel G; Garg, Amit X; Quinn, Robert R (2018). Thiazide Diuretic Dose and Risk of Kidney Stones in Older Adults: A Retrospective Cohort Study. Canadian journal of kidney health and disease, 5, p. 2054358118787480. Sage 10.1177/2054358118787480


Steinmann, Michael E.; Schmidt, Remo S.; Pereira de Macêdo, Juan; Kunz Renggli, Christina; Bütikofer, Peter; Rentsch, Doris; Mäser, Pascal; Sigel, Erwin (2017). Identification and characterization of the three members of the CLC family of anion transport proteins in Trypanosoma brucei. PLoS ONE, 12(12), pp. 1-18. Public Library of Science 10.1371/journal.pone.0188219

Bertini, Simone; Chicca, Andrea; Gado, Francesca; Arena, Chiara; Nieri, Daniela; Digiacomo, Maria; Saccomanni, Giuseppe; Zhao, Pingwei; Abood, Mary E; Macchia, Marco; Gertsch, Jürg; Manera, Clementina (2017). Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor. Bioorganic & medicinal chemistry, 25(24), pp. 6427-6434. Elsevier 10.1016/j.bmc.2017.10.015

Albrecht, Christiane; Baker, Julie C; Blundell, Cassidy; Chavez, Shawn L; Carbone, Lucia; Chamley, Larry; Hannibal, Roberta L; Illsley, Nick; Kurre, Peter; Laurent, Louise C; McKenzie, Charles; Morales-Prieto, Diana; Pantham, Priyadarshini; Paquette, Alison; Powell, Katie; Price, Nathan; Rao, Balaji M; Sadovsky, Yoel; Salomon, Carlos; Tuteja, Geetu; ... (2017). IFPA meeting 2016 workshop report I: Genomic communication, bioinformatics, trophoblast biology and transport systems. Placenta, 60 Suppl 1, S5-S9. Elsevier 10.1016/j.placenta.2017.01.103

Rölli, Matthias Andreas; Ruffieux-Daidiée, Dorothée; Stooss, Amandine; El Mokh, Oussama; Phillips, Wayne A; Dettmer, Matthias; Charles, Roch-Philippe (2017). PIK3CAH1047R-induced paradoxical ERK activation results in resistance to BRAFV600E specific inhibitors in BRAFV600E PIK3CAH1047R double mutant thyroid tumors. OncoTarget, 8(61), pp. 103207-103222. Impact Journals LLC 10.18632/oncotarget.21732

Chicca, Andrea; Berg, Regina; Jessen, Henning J; Marck, Nicolas; Schmid, Fabian; Burch, Patrick; Gertsch, Jürg; Gademann, Karl (2017). Biological evaluation of pyridone alkaloids on the endocannabinoid system. Bioorganic & medicinal chemistry, 25(22), pp. 6102-6114. Elsevier 10.1016/j.bmc.2017.02.031

Wongsamitkul, Nisa; Maldifassi, Maria Constanza; Simeone, Xenia Maria Laura; Baur, Roland; Ernst, Margot; Sigel, Erwin (2017). α subunits in GABAA receptors are dispensable for GABA and diazepam action. Scientific Reports, 7(1), p. 15498. Nature Publishing Group 10.1038/s41598-017-15628-7

Gottier, Petra; Serricchio, Mauro; Vitale, Rita; Corcelli, Angela; Bütikofer, Peter (2017). Cross-species complementation of bacterial- and eukaryotic-type cardiolipin synthases. Microbial cell, 4(11), pp. 376-383. Shared Science Publishers OG 10.15698/mic2017.11.598

Reynoso, Ines del Carmen; Najar-Guerrero, Israel; Escareño, Noé; Flores-Soto, Mario Eduardo; Gertsch, Jürg; Viveros-Paredes, Juan Manuel (2017). An Endocannabinoid Uptake Inhibitor from Black Pepper Exerts Pronounced Anti-Inflammatory Effects in Mice. Journal of agricultural and food chemistry, 65(43), pp. 9435-9442. American Chemical Society 10.1021/acs.jafc.7b02979

Kappel, Sven; dos Santos Marques, Ines Joao; Zoni, Eugenio; Stoklosa, Paulina Agnieszka; Peinelt, Christine; Mercader Huber, Nadia; Kruithof-de Julio, Marianna; Borgström, Anna (2017). Store-Operated Ca2+ Entry as a Prostate Cancer Biomarker — a Riddle with Perspectives. Current Molecular Biology Reports, 3(4), pp. 208-217. Springer 10.1007/s40610-017-0072-8

Patsenker, Eleonora; Chicca, Andrea; Petrucci, Vanessa; Moghadamrad, Sheida; De Gottardi, Andrea; Hampe, Jochen; Gertsch, Jürg; Semmo, Nasser; Stickel, Felix (2017). 4-O'-methylhonokiol protects from alcohol/carbon tetrachloride-induced liver injury in mice. Journal of molecular medicine JMM, 95(10), pp. 1077-1089. Springer 10.1007/s00109-017-1556-y

Ritzmann, Noah; Thoma, Johannes; Hirschi, Stephan; Kalbermatter, David; Fotiadis, Dimitrios José; Müller, Daniel J (2017). Fusion Domains Guide the Oriented Insertion of Light-Driven Proton Pumps into Liposomes. Biophysical journal, 113(6), pp. 1181-1186. Biophysical Society 10.1016/j.bpj.2017.06.022

Dhayat, Nasser; Pathare, Ganesh Tukaram; Anderegg, Manuel; Vogt, Bruno; Fuster, Daniel Guido (2017). Incomplete dRTA in kidney stone formers: diagnostic performance of furosemide/fludrocortisone testing and non-provocative clinical parameters. Clinical journal of the American Society of Nephrology, 12(9), pp. 1507-1517. American Society of Nephrology 10.2215/CJN.01320217

Verchère, Alice; Ou, Wei-Lin; Ploier, Birgit; Morizumi, Takefumi; Goren, Michael A; Bütikofer, Peter; Ernst, Oliver P; Khelashvili, George; Menon, Anant K (2017). Light-independent phospholipid scramblase activity of bacteriorhodopsin from Halobacterium salinarum. Scientific Reports, 7(1), p. 9522. Nature Publishing Group 10.1038/s41598-017-09835-5

Petrucci, Vanessa; Chicca, Andrea; Glasmacher, Sandra Patricia; Paloczi, Janos; Cao, Zongxian; Pacher, Pal; Gertsch, Jürg (2017). Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage. Scientific Reports, 7(1), p. 9560. Nature Publishing Group 10.1038/s41598-017-09808-8

Laskowski, Pawel R; Pfreundschuh, Moritz; Stauffer, Mirko; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José; Müller, Daniel J (2017). High-Resolution Imaging and Multiparametric Characterization of Native Membranes by Combining Confocal Microscopy and an Atomic Force Microscopy-Based Toolbox. ACS nano, 11(8), pp. 8292-8301. American Chemical Society 10.1021/acsnano.7b03456

Dalghi Gens, Marianela Gisela; Ferreira-Gomes, Mariela; Montalbetti, Nicolas; Simonin, Alexandre; Strehler, Emanuel E; Hediger, Matthias; Rossi, Juan Pablo (2017). Cortical cytoskeleton dynamics regulates plasma membrane calcium ATPase isoform-2 (PMCA2) activity. Biochimica et biophysica acta - molecular cell research, 1864(8), pp. 1413-1424. Elsevier 10.1016/j.bbamcr.2017.05.014

Pujol Gimenez, Jonai; Hediger, Matthias; Gyimesi, Gergely (2017). A novel proton transfer mechanism in the SLC11 family of divalent metal ion transporters. Scientific Reports, 7(1), p. 6194. Nature Publishing Group 10.1038/s41598-017-06446-y

Lüscher, Benjamin; Marini, Camilla; Jörger Messerli, Marianne; Huang, Xiao; Hediger, Matthias; Albrecht, Christiane; Baumann, Marc Ulrich; Surbek, Daniel (2017). Placental glucose transporter (GLUT)-1 is down-regulated in preeclampsia. Placenta, 55, pp. 94-99. Elsevier 10.1016/j.placenta.2017.04.023

Kalbermatter, David; Chiu, Po-Lin; Jeckelmann, Jean-Marc; Ucurum Fotiadis, Zöhre; Walz, Thomas; Fotiadis, Dimitrios José (2017). Electron crystallography reveals that substrate release from the PTS IIC glucose transporter is coupled to a subtle conformational change. Journal of structural biology, 199(1), pp. 39-45. Elsevier 10.1016/j.jsb.2017.05.005

von Rotz, Robin; Kometer, Michael; Dornbierer, Dario; Gertsch, Jürg; Gachet Otanez, Maria Salomé; Vollenweider, Franz X; Seifritz, Erich; Bosch, Oliver G; Quednow, Boris B (2017). Neuronal oscillations and synchronicity associated with gamma-hydroxybutyrate during resting-state in healthy male volunteers. Psychopharmacology, 234(13), pp. 1957-1968. Springer 10.1007/s00213-017-4603-z

Chicca, Andrea; Nicolussi, Simon; Bartholomäus, Ruben; Blunder, Martina; Aparisi Rey, Alejandro; Petrucci, Vanessa; Reynoso, Ines del Carmen; Viveros-Paredes, Juan Manuel; Dalghi Gens, Marianela Gisela; Lutz, Beat; Schiöth, Helgi B; Soeberdt, Michael; Abels, Christoph; Charles, Roch-Philippe; Altmann, Karl-Heinz; Gertsch, Jürg (2017). Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 114(25), E5006-E5015. National Academy of Sciences NAS 10.1073/pnas.1704065114

Peng, J-B; Suzuki, Y; Gyimesi, Gergely; Hediger, Matthias (2017). TRPV5 and TRPV6 calcium-selective channels. In: Ashot Kozak, Juliusz; Putney, James Jr. (eds.) Calcium Entry Channels in Non-Excitable Cells. Methods in Signal Transduction Series (pp. 241-274). CRC Press

Gertsch, Jürg (2017). Cannabimimetic phytochemicals in the diet - an evolutionary link to food selection and metabolic stress adaptation? British journal of pharmacology, 174(11), pp. 1464-1483. Wiley-Blackwell 10.1111/bph.13676

Nisa Hernández, Lluís; Häfliger, Pascal; Poliakova, Michaela; Giger, Roland; Francica, Paola; Aebersold, Daniel; Charles, Roch-Philippe; Zimmer, Yitzhak; Medova, Michaela (2017). PIK3CA hotspot mutations differentially impact responses to MET targeting in MET-driven and non-driven preclinical cancer models. Molecular cancer, 16(1), p. 93. BioMed Central 10.1186/s12943-017-0660-5

Pfreundschuh, Moritz; Harder, Daniel; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José; Müller, Daniel J (2017). Detecting Ligand-Binding Events and Free Energy Landscape while Imaging Membrane Receptors at Subnanometer Resolution. Nano letters, 17(5), pp. 3261-3269. American Chemical Society 10.1021/acs.nanolett.7b00941

Farine, Luce; Jelk, Jennifer; Choi, Jae-Yeon; Voelker, Dennis R; Nunes, Jon; Smith, Terry K; Bütikofer, Peter (2017). Phosphatidylserine synthase 2 and phosphatidylserine decarboxylase are essential for aminophospholipid synthesis in Trypanosoma brucei. Molecular microbiology, 104(3), pp. 412-427. Blackwell Science 10.1111/mmi.13637

Orekhov, Philipp; Bothe, Arne; Steinhoff, Heinz-Jürgen; Shaitan, Konstantin V; Raunser, Stefan; Fotiadis, Dimitrios José; Schlesinger, Ramona; Klare, Johann P; Engelhard, Martin (2017). Sensory Rhodopsin I and Sensory Rhodopsin II Form Trimers of Dimers in Complex with their Cognate Transducers. Photochemistry and photobiology, 93(3), pp. 796-804. Blackwell Publishing 10.1111/php.12763

Hinard, Valérie; Britan, Aurore; Schaeffer, Mathieu; Zahn-Zabal, Monique; Thomet, Urs; Rougier, Jean-Sébastien; Bairoch, Amos; Abriel, Hugues; Gaudet, Pascale (2017). Annotation of functional impact of voltage-gated sodium channel mutations. Human mutation, 38(5), pp. 485-493. Wiley-Blackwell 10.1002/humu.23191

El Mokh, Oussama; Ruffieux-Daidié, Dorothée; Rölli, Matthias Andreas; Stooss, Amandine; Phillips, Wayne A; Gertsch, Jürg; Dettmer, Matthias; Charles, Roch-Philippe (2017). Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo. OncoTarget, 8(15), pp. 24604-24620. Impact Journals LLC 10.18632/oncotarget.15599

Steinmann, Michael Eduard; Schmidt, Remo S; Bütikofer, Peter; Mäser, Pascal; Sigel, Erwin (2017). TbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes. Scientific Reports, 7(1), p. 656. Nature Publishing Group 10.1038/s41598-017-00752-1

Russo-Abrahão, Thais; Koeller, Carolina Macedo; Steinmann, Michael Eduard; Silva-Rito, Stephanie; Marins-Lucena, Thaissa; Alves-Bezerra, Michele; Lima-Giarola, Naira Ligia; de-Paula, Iron Francisco; González Salgado, Amaia; Sigel, Erwin; Bütikofer, Peter; Gondim, Katia Calp; Heise, Norton; Meyer-Fernandes, José Roberto (2017). H+-dependent inorganic phosphate uptake in Trypanosoma brucei is influenced by myo-inositol transporter. Journal of bioenergetics and biomembranes, 49(2), pp. 183-194. Springer 10.1007/s10863-017-9695-y

Vermij, Sarah Helena; Abriel, Hugues; van Veen, Toon A B (2017). Refining the molecular organization of the cardiac intercalated disc. Cardiovascular research, 113(3), pp. 259-275. Oxford University Press 10.1093/cvr/cvw259

Maldifassi, Maria Constanza; Sigel, Erwin (2017). Functional sites for anesthetics in GABAA receptors. OncoTarget, 8(7), pp. 10779-10780. Impact Journals LLC 10.18632/oncotarget.14616

Lochner, Martin; Hemmings, Jennifer Luise; Leuenberger, Michele; Meyer, Jonas; Bartlome, Pascal; Perozzo, Alyssa Victoria; Frenguelli, Bruno G.; Winfield, Ian; Ladds, Graham (12 February 2017). Molecular Tools for the Cellular Study of Adenosine A1 Receptors (Unpublished). In: GDCh/SCS conference on Frontiers in Medicinal Chemistry. Bern. 12.-15.02.2017.

Leuenberger, Michele; Lochner, Martin; Bernhard, Stephanie; Stieger, Bruno (12 February 2017). Synthesis of Fluorescent Bile Salt Derivatives and Their Utility as Tracers of the Canalicular Lipid Transporter System (Unpublished). In: GDCh/SCS conference on Frontiers in Medicinal Chemistry. Bern. 12.-15.2.2017.

Ruepp, Marc-David; Wei, Hao; Leuenberger, Michele; Lochner, Martin; Thompson, Andrew James (2017). The binding orientation of structurally-related ligands can differ; A cautionary note. Neuropharmacology, 119, pp. 48-61. Elsevier 10.1016/j.neuropharm.2017.01.023

Gachet Otanez, Maria Salomé; Schubert, Alexandra; Calarco, Serafina; Boccard, Julien; Gertsch, Jürg (2017). Targeted metabolomics shows plasticity in the evolution of signaling lipids and uncovers old and new endocannabinoids in the plant kingdom. Scientific Reports, 7, p. 41177. Nature Publishing Group 10.1038/srep41177

Thompson, Andrew J.; Metzger, Simon; Lochner, Martin; Ruepp, Marc-David (2017). The binding orientation of epibatidine at α7 nACh receptors. Neuropharmacology, 116, pp. 421-428. Elsevier 10.1016/j.neuropharm.2017.01.008

Ontsouka, Edgar; Huang, Xiao; Aliyev, Eldar; Albrecht, Christiane (2017). In vitro characterization and endocrine regulation of cholesterol and phospholipid transport in the mammary gland. Molecular and cellular endocrinology, 439, pp. 35-45. Elsevier Ireland 10.1016/j.mce.2016.10.016

Mathieu, Christoph; Pereira de Macêdo, Juan; Hürlimann, Daniel; Wirdnam, Corina; Haindrich, Alexander; Suter, Marianne; González Salgado, Amaia; Schmidt, Remo; Inbar, Ehud; Mäser, Pascal; Bütikofer, Peter; Zilberstein, Dan; Rentsch, Doris (2017). Arginine and Lysine Transporters Are Essential for Trypanosoma brucei. PLoS ONE, 12(1), e0168775. Public Library of Science 10.1371/journal.pone.0168775

Soethoudt, Marjolein; Grether, Uwe; Fingerle, Jürgen; Grim, Travis W; Fezza, Filomena; de Petrocellis, Luciano; Ullmer, Christoph; Rothenhäusler, Benno; Perret, Camille; van Gils, Noortje; Finlay, David; MacDonald, Christa; Chicca, Andrea; Gens, Marianela Dalghi; Stuart, Jordyn; de Vries, Henk; Mastrangelo, Nicolina; Xia, Lizi; Alachouzos, Georgios; Baggelaar, Marc P; ... (2017). Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity. Nature communications, 8(13958), p. 13958. Nature Publishing Group 10.1038/ncomms13958

Gottier, Petra; González Salgado, Amaia; Menon, Anant K; Liu, Yuk-Chien; Acosta-Serrano, Alvaro; Bütikofer, Peter (2017). RFT1 affects GPI anchor glycosylation. Journal of biological chemistry, 292(3), pp. 1103-1111. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M116.758367

Albano, Giuseppe; Dolder, Silvia; Siegrist, Mark; Mercier-Zuber, Annie; Auberson, Muriel; Stoudmann, Candice; Hofstetter, Wilhelm; Bonny, Olivier; Fuster, Daniel Guido (2017). Increased bone resorption by osteoclast-specific deletion of the sodium/calcium exchanger isoform 1 (NCX1). Pflügers Archiv : European journal of physiology, 469(2), pp. 225-233. Springer 10.1007/s00424-016-1923-5

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Bauer, Mark; Chicca, Andrea; Tamborrini, Marco; Eisen, David; Lerner, Raissa; Lutz, Beat; Poetz, Oliver; Pluschke, Gerd; Gertsch, Jürg (2012). Identification and quantification of a new family of peptide endocannabinoids (Pepcans) showing negative allosteric modulation at CB1 receptors. Journal of biological chemistry, 287(44), pp. 36944-67. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.382481

Serra, Silvia; Chicca, Andrea; Delogu, Giovanna; Vázquez-Rodríguez, Saleta; Santana, Lourdes; Uriarte, Eugenio; Casu, Laura; Gertsch, Jürg (2012). Synthesis and cytotoxic activity of non-naturally substituted 4-oxycoumarin derivatives. Bioorganic and medicinal chemistry letters, 22(18), pp. 5791-4. New York, N.Y.: Pergamon 10.1016/j.bmcl.2012.07.099

Chicca, Andrea; Marazzi, Janine; Nicolussi, Simon; Gertsch, Jürg (2012). Evidence for bidirectional endocannabinoid transport across cell membranes. Journal of biological chemistry, 287(41), pp. 34660-82. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.373241

Chicca, A; Marazzi, J; Gertsch, J (2012). The antinociceptive triterpene β-amyrin inhibits 2-arachidonoylglycerol (2-AG) hydrolysis without directly targeting cannabinoid receptors. British journal of pharmacology, 167(8), pp. 1596-608. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2012.02059.x

Yang, Peng; Myint, Kyaw-Zeyar; Tong, Qin; Feng, Rentian; Cao, Haiping; Almehizia, Abdulrahman A; Alqarni, Mohammed Hamed; Wang, Lirong; Bartlow, Patrick; Gao, Yingdai; Gertsch, Jürg; Teramachi, Jumpei; Kurihara, Noriyoshi; Roodman, Garson David; Cheng, Tao; Xie, Xiang-Qun (2012). Lead discovery, chemistry optimization, and biological evaluation studies of novel biamide derivatives as CB2 receptor inverse agonists and osteoclast inhibitors. Journal of medicinal chemistry, 55(22), pp. 9973-87. Easton, Pa.: American Chemical Society 10.1021/jm301212u

Bénard, Giovanni; Massa, Federico; Puente, Nagore; Lourenço, Joana; Bellocchio, Luigi; Soria-Gómez, Edgar; Matias, Isabel; Delamarre, Anna; Metna-Laurent, Mathilde; Cannich, Astrid; Hebert-Chatelain, Etienne; Mulle, Christophe; Ortega-Gutiérrez, Silvia; Martín-Fontecha, Mar; Klugmann, Matthias; Guggenhuber, Stephan; Lutz, Beat; Gertsch, Jürg; Chaouloff, Francis; López-Rodríguez, María Luz; ... (2012). Mitochondrial CB₁ receptors regulate neuronal energy metabolism. Nature neuroscience, 15(4), pp. 558-64. New York, N.Y.: Nature America 10.1038/nn.3053

Horváth, Béla; Mukhopadhyay, Partha; Kechrid, Malek; Patel, Vivek; Tanchian, Galin; Wink, David A; Gertsch, Jürg; Pacher, Pál (2012). β-Caryophyllene ameliorates cisplatin-induced nephrotoxicity in a cannabinoid 2 receptor-dependent manner. Free radical biology & medicine, 52(8), pp. 1325-33. San Diego, Calif.: Elsevier 10.1016/j.freeradbiomed.2012.01.014

Anavi-Goffer, Sharon; Baillie, Gemma; Irving, Andrew J; Gertsch, Jürg; Greig, Iain R; Pertwee, Roger G; Ross, Ruth A (2012). Modulation of L-α-lysophosphatidylinositol/GPR55 mitogen-activated protein kinase (MAPK) signaling by cannabinoids. Journal of biological chemistry, 287(1), pp. 91-104. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M111.296020

Gertsch, J; Anavi-Goffer, S (2012). Methylhonokiol attenuates neuroinflammation: a role for cannabinoid receptors? 9. J Neuroinflammation 10.1186/1742-2094-9-135

Kuhn, A; Fotiadis, D (2012). Membrane proteins - at the core of life. Public service review - European science & technology, 17 Newcastle-under-Lyme, UK: publicservice.co.uk Ltd

Trachsel, Christian; Siegemund, Doreen; Kämpfer, Urs; Kopp, Lukas; Bühr, Claudia; Grossmann, Jonas; Lüthi, Christoph; Cunningham, Monica; Nentwig, Wolfgang; Kuhn-Nentwig, Lucia; Schürch, Stefan; Schaller, Johann (2012). Multicomponent venom of the spider Cupiennius salei: a bioanalytical investigation applying different strategies. FEBS journal, 279(15), pp. 2683-2694. Oxford: Wiley-Blackwell 10.1111/j.1742-4658.2012.08650.x

Acharya, G; Albrecht, C; Benton, S J; Cotechini, T; Dechend, R; Dilworth, M R; Duttaroy, A K; Grotmol, T; Heazell, A E; Jansson, T; Johnstone, E D; Jones, H N; Jones, R L; Lager, S; Laine, K; Nagirnaja, L; Nystad, M; Powell, T; Redman, C; Sadovsky, Y; ... (2012). IFPA Meeting 2011 workshop report I: Placenta: Predicting future health; roles of lipids in the growth and development of feto-placental unit; placental nutrient sensing; placental research to solve clinical problems--a translational approach. Placenta, 33 Suppl, S4-8. Amsterdam: Elsevier 10.1016/j.placenta.2011.11.015

Ontsouka, E.C.; Burgener, I.A.; Luckschander-Zeller, N; Blum, J.W.; Albrecht, C. (2012). Fish-meal diet enriched with omega-3 PUFA and treatment of canine chronic enteropathies. European journal of lipid science and technology, 2012(114), pp. 412-422. Weinheim: Wiley-Blackwell 10.1002/ejlt.201100343

Körner, Meike; Wenger, Fabian; Nikitina, Liudmila; Baumann, Marc; Surbek, Daniel; Albrecht, Christiane (2012). The lipid transporters ABCA1 and ABCG1 are differentially expressed in syncytiotrophoblasts of preeclamptic and IUGR placentas. Placenta, 2012(9), A91. Elsevier

Lüscher, Benjamin; Messerli, Marianne; Surbek, Daniel; Sager, Ruth; Albrecht, Christiane; Hediger, Matthias; Baumann, Marc (2012). Placental glucose transporter (Glut)-1 expression in preeclampsia. Placenta, 33(9), A90-A90. Elsevier

Eisele, Nicole; Gennari, Carine; Albrecht, Christiane; Baumann, Marc; Surbek, Daniel; Mohaupt, Markus (2012). Does Aldosterone participate in placental angiogenesis via PLGF? Pregnancy hypertension, 2(3), p. 245. Amsterdam: Elsevier Science 10.1016/j.preghy.2012.04.121

Körner, M; Wenger, F; NIkitina, L; Baumann, M; Surbek, D; Albrecht, C (2012). PP141. The lipid transporters ABCA1 and ABCG1 are differentially expressed in preeclamptic and IUGR placentas. Pregnancy hypertension, 2(3), pp. 315-316. Elsevier Science 10.1016/j.preghy.2012.04.252


Gertsch, Jürg; Viveros Paredes, Juan Manuel; Taylor, Peter (2011). Plant immunostimulants-Scientific paradigm or myth? Journal of ethnopharmacology, 136(3), pp. 385-391. Shannon: Elsevier Science Ireland 10.1016/j.jep.2010.06.044

Kovacs, Gergely; Danko, Tamas; Bergeron, Marc J; Balazs, Bernadett; Suzuki, Yoshiro; Zsembery, Akos; Hediger, Matthias A (2011). Heavy metal cations permeate the TRPV6 epithelial cation channel. Cell calcium, 49(1), pp. 43-55. Amsterdam: Elsevier 10.1016/j.ceca.2010.11.007

Landowski, Christopher P; Bolanz, Katrin A; Suzuki, Yoshiro; Hediger, Matthias A (2011). Chemical inhibitors of the calcium entry channel TRPV6. Pharmaceutical research, 28(2), pp. 322-30. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s11095-010-0249-9

Nikitina, L; Wenger, F; Baumann, M; Surbek, D; Körner, M; Albrecht, C (2011). Expression and localization pattern of ABCA1 in diverse human placental primary cells and tissues. Placenta, 32(6), pp. 420-30. Amsterdam: Elsevier 10.1016/j.placenta.2011.03.003

Mani, O; Körner, M; Ontsouka, C E; Sorensen, M T; Sejrsen, K; Bruckmaier, R M; Albrecht, C (2011). Identification of ABCA1 and ABCG1 in milk fat globules and mammary cells--implications for milk cholesterol secretion. Journal of dairy science, 94(3), pp. 1265-76. Savoy, Ill.: American Dairy Science Association 10.3168/jds.2010-3521

Lottaz, Daniel; Maurer, Christoph A; Noël, Agnès; Blacher, Silvia; Huguenin, Maya; Nievergelt, Alexandra; Niggli, Verena; Kern, Alexander; Müller, Stefan; Seibold, Frank; Friess, Helmut; Becker-Pauly, Christoph; Stöcker, Walter; Sterchi, Erwin E (2011). Enhanced activity of meprin-?, a pro-migratory and pro-angiogenic protease, in colorectal cancer. PLoS ONE, 6(11), e26450. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0026450

Patel, Dipesh C; Albrecht, Christiane; Pavitt, Darrell; Paul, Vijay; Pourreyron, Celine; Newman, Simon P; Godsland, Ian F; Valabhji, Jonathan; Johnston, Desmond G (2011). Type 2 diabetes is associated with reduced ATP-binding cassette transporter A1 gene expression, protein and function. PLoS ONE, 6(7), e22142. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0022142

Albrecht, Christiane; Nikitina, Liudmila; Wenger, Fabian Oliver; Baumann, Marc; Surbek, Daniel; Körner Jachertz, Meike (2011). ABCA1 and placental cholesterol efflux: a reply. Placenta, 32(9), pp. 710-711. Amsterdam: Elsevier 10.1016/j.placenta.2011.06.006

Greganova, Eva; Altmann, Michael; Bütikofer, Peter (2011). Unique modifications of translation elongation factors. FEBS journal, 278(15), pp. 2613-24. Oxford: Wiley-Blackwell 10.1111/j.1742-4658.2011.08199.x

Serricchio, Mauro; Bütikofer, Peter (2011). Trypanosoma brucei: a model micro-organism to study eukaryotic phospholipid biosynthesis. FEBS journal, 278(7), pp. 1035-46. Oxford: Wiley-Blackwell 10.1111/j.1742-4658.2011.08012.x

Jeckelmann, Jean-Marc; Harder, Daniel; Mari, Stefania A; Meury, Marcel; Ucurum, Zöhre; Müller, Daniel J; Erni, Bernhard; Fotiadis, Dimitrios (2011). Structure and function of the glucose PTS transporter from Escherichia coli. Journal of structural biology, 176(3), pp. 395-403. San Diego, Calif.: Elsevier 10.1016/j.jsb.2011.09.012

Bergeron, Marc J.; Boggavarapu, Rajendra; Meury, Marcel; Ucurum, Zöhre; Caron, Luc; Isenring, Paul; Hediger, Matthias A.; Fotiadis, Dimitrios (2011). Frog oocytes to unveil the structure and supramolecular organization of human transport proteins. PLoS ONE, 6(7), e21901. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0021901

Meury, Marcel; Harder, Daniel; Ucurum, Zöhre; Boggavarapu, Rajendra; Jeckelmann, Jean-Marc; Fotiadis, Dimitrios (2011). Structure determination of channel and transport proteins by high-resolution microscopy techniques. Biological chemistry, 392(1-2), pp. 143-50. Berlin: Walter de Gruyter 10.1515/BC.2011.004

Jeckelmann, Jean-Marc; Palacin, Manuel; Fotiadis, Dimitrios (2011). A tool for the qualitative comparison of membrane-embedded and detergent-solubilized membrane protein structures in projection. Journal of structural biology, 173(2), pp. 375-81. San Diego, Calif.: Elsevier 10.1016/j.jsb.2010.09.005

Ilgü, Hüseyin; Turan, Taylan; Şanli-Mohameda, Gülşa (2011). Immobilization and characterization of recombinant esterase enzyme on chitosan nanoparticles. Journal of macromolecular science. Part A - pure and applied chemistry, 48(9), pp. 713-721. Taylor & Francis 10.1080/10601325.2011.596050

Palanivelu, Dinesh V; Goepfert, Arnaud; Meury, Marcel; Guye, Patrick; Dehio, Christoph; Schirmer, Tilman (2011). Fic domain-catalyzed adenylylation: insight provided by the structural analysis of the type IV secretion system effector BepA. Protein science, 20(3), pp. 492-9. Malden, Mass.: Wiley-Blackwell 10.1002/pro.581

Sigel, Erwin; Baur, Roland; Rácz, Ildiko; Marazzi, Janine; Smart, Trevor G; Zimmer, Andreas; Gertsch, Jürg (2011). The major central endocannabinoid directly acts at GABA(A) receptors. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 108(44), pp. 18150-5. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.1113444108

Marazzi, Janine; Kleyer, Jonas; Paredes, Juan Manuel Viveros; Gertsch, Jürg (2011). Endocannabinoid content in fetal bovine sera - unexpected effects on mononuclear cells and osteoclastogenesis. Journal of immunological methods, 373(1-2), pp. 219-28. Amsterdam: Elsevier 10.1016/j.jim.2011.08.021

Nievergelt, Andreas; Marazzi, Janine; Schoop, Roland; Altmann, Karl-Heinz; Gertsch, Jürg (2011). Ginger phenylpropanoids inhibit IL-1beta and prostanoid secretion and disrupt arachidonate-phospholipid remodeling by targeting phospholipases A2. Journal of immunology, 187(8), pp. 4140-50. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.1100880

Schuehly, Wolfgang; Paredes, Juan Manuel Viveros; Kleyer, Jonas; Huefner, Antje; Anavi-Goffer, Sharon; Raduner, Stefan; Altmann, Karl-Heinz; Gertsch, Jürg (2011). Mechanisms of osteoclastogenesis inhibition by a novel class of biphenyl-type cannabinoid CB(2) receptor inverse agonists. Chemistry & biology, 18(8), pp. 1053-64. San Francisco, Calif.: Current Biology Ltd. 10.1016/j.chembiol.2011.05.012

Ritchie, M R; Gertsch, J; Klein, P; Schoop, R (2011). Effects of Echinaforce® treatment on ex vivo-stimulated blood cells. Phytomedicine, 18(10), pp. 826-31. Amsterdam: Elsevier 10.1016/j.phymed.2011.05.011

Maffei, Massimo E; Gertsch, Jürg; Appendino, Giovanni (2011). Plant volatiles: production, function and pharmacology. Natural product reports, 28(8), pp. 1359-80. Cambridge: Royal Society of Chemistry 10.1039/c1np00021g

Gertsch, Jürg (2011). Natural products in chemical biology. Current drug targets, 12(11), pp. 1513-4. Hilversum: Bentham Science Publishers 10.2174/138945011798109518

Ramesha, B T; Gertsch, Jürg; Ravikanth, G; Priti, V; Ganeshaiah, K N; Uma Shaanker, R (2011). Biodiversity and chemodiversity: future perspectives in bioprospecting. Current drug targets, 12(11), pp. 1515-30. Hilversum: Bentham Science Publishers

Zhang, Yuxun; Xie, Zhaojun; Wang, Lirong; Schreiter, Brielle; Lazo, John S; Gertsch, Jurg; Xie, Xiang-Qun (2011). Mutagenesis and computer modeling studies of a GPCR conserved residue W5.43(194) in ligand recognition and signal transduction for CB2 receptor. International immunopharmacology, 11(9), pp. 1303-10. Amsterdam: Elsevier 10.1016/j.intimp.2011.04.013

Gertsch, Jürg (2011). Botanical drugs, synergy, and network pharmacology: forth and back to intelligent mixtures. Planta medica, 77(11), pp. 1086-98. Stuttgart: Thieme 10.1055/s-0030-1270904

Schiess, Raphael; Gertsch, Jürg; Schweizer, W Bernd; Altmann, Karl-Heinz (2011). Stereoselective synthesis of 12,13-cyclopropyl-epothilone B and side-chain-modified variants. Organic letters, 13(6), pp. 1436-9. Washington, D.C.: American Chemical Society 10.1021/ol200114k

Bergeron, Marc J; Bürzle, Marc; Kovacs, Gergely; Simonin, Alexandre; Hediger, Matthias A (2011). Synthesis, maturation, and trafficking of human Na+-dicarboxylate cotransporter NaDC1 requires the chaperone activity of cyclophilin B. Journal of biological chemistry, 286(13), pp. 11242-53. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M110.171728

Sigel, Erwin; Lüscher, Benjamin P (2011). A closer look at the high affinity benzodiazepine binding site on GABAA receptors. Current topics in medicinal chemistry, 11(2), pp. 241-6. Hilversum: Bentham Science Publishers 10.2174/156802611794863562


Lis, Annette; Zierler, Susanna; Peinelt, Christine; Fleig, Andrea; Penner, Reinhold (2010). A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating. Journal of general physiology, 136(6), pp. 673-686. Rockefeller University Press 10.1085/jgp.201010484

Bogeski, Ivan; Al-Ansary, Dalia; Qu, Bin; Niemeyer, Barbara A; Hoth, Markus; Peinelt, Christine (2010). Pharmacology of ORAI channels as a tool to understand their physiological functions. Expert review of clinical pharmacology, 3(3), pp. 291-303. Taylor & Francis 10.1586/ecp.10.23

Bogeski, Ivan; Kummerow, Carsten; Al-Ansary, Dalia; Schwarz, Eva C; Koehler, Richard; Kozai, Daisuke; Takahashi, Nobuaki; Peinelt, Christine; Griesemer, Desiree; Bozem, Monika; Mori, Yasuo; Hoth, Markus; Niemeyer, Barbara A (2010). Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling. Science signaling, 3(115), ra24. American Association for the Advancement of Science 10.1126/scisignal.2000672

Ambort, Daniel; Brellier, Florence; Becker-Pauly, Christoph; Stöcker, Walter; Andrejevic-Blant, Snezana; Chiquet, Matthias; Sterchi, Erwin E (2010). Specific processing of tenascin-C by the metalloprotease meprinbeta neutralizes its inhibition of cell spreading. Matrix biology, 29(1), pp. 31-42. Amsterdam: Elsevier 10.1016/j.matbio.2009.08.007

Hofstetter, Willy; Siegrist, Mark; Simonin, Alexandre; Bonny, Olivier; Fuster, Daniel G (2010). Sodium/hydrogen exchanger NHA2 in osteoclasts: subcellular localization and role in vitro and in vivo. Bone, 47(2), pp. 331-340. New York, N.Y.: Elsevier 10.1016/j.bone.2010.04.605

Albrecht, C; Nikitina, L; Wenger, F; Baumann, M; Surbek, D; Körner, M (2010). Localisation of ABCA1 in first trimester and term placental tissues. Placenta, 31(8), pp. 741-2. Amsterdam: Elsevier 10.1016/j.placenta.2010.05.010

Mani, Orlando; Körner, Meike; Sorensen, Martin T; Sejrsen, Kristen; Wotzkow, Carlos; Ontsouka, Corneille E; Friis, Robert R; Bruckmaier, Rupert M; Albrecht, Christiane (2010). Expression, localization, and functional model of cholesterol transporters in lactating and nonlactating mammary tissues of murine, bovine, and human origin. American journal of physiology - regulatory, integrative and comparative physiology, 299(2), R642-54. Bethesda, Md.: American Physiological Society 10.1152/ajpregu.00723.2009

Simonin, Alexandre; Fuster, Daniel Guido (2010). Nedd4-1 and beta-arrestin-1 are key regulators of Na+/H+ exchanger 1 ubiquitylation, endocytosis, and function. Journal of biological chemistry, 285(49), pp. 38293-38303. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M110.115089

Steinke, K; Guertler, P; Paul, V; Wiedemann, S; Ettle, T; Albrecht, C; Meyer, H H D; Spiekers, H; Schwarz, F J (2010). Effects of long-term feeding of genetically modified corn (event MON810) on the performance of lactating dairy cows. Journal of animal physiology and animal nutrition, 94(5), e185-93. Berlin: Blackwell Science 10.1111/j.1439-0396.2010.01003.x

Ontsouka, C E; Burgener, I A; Mani, O; Albrecht, C (2010). Polyunsaturated fatty acid-enriched diets used for the treatment of canine chronic enteropathies decrease the abundance of selected genes of cholesterol homeostasis. Domestic animal endocrinology, 38(1), pp. 32-7. New York, N.Y.: Elsevier 10.1016/j.domaniend.2009.08.001

Guerteler, P; Paul, V; Steinke, K; Wiedemann, S; Preissinger, W; Albrecht, C; Spiekers, H; Schwarz, F.J.; Meyer, H.H.D. (2010). Long-term feeding of genetically modified corn (MON510)- Fate of cry1Ab DNA and recombinant protein during the metabolism of the dairy cow. Livestock science, 2010(131), pp. 250-259. Amsterdam: Elsevier 10.1016/j.livsci.2010.04.010

Altmann, Michael; Linder, Patrick (2010). Power of yeast for analysis of eukaryotic translation initiation. Journal of biological chemistry, 285(42), pp. 31907-12. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.R110.144196

Smith, Terry K; Bütikofer, Peter (2010). Lipid metabolism in Trypanosoma brucei. Molecular and biochemical parasitology, 172(2), pp. 66-79. Amsterdam: Elsevier 10.1016/j.molbiopara.2010.04.001

Xue, Gondga; von Schubert, Conrad; Hermann, Pascal; Peyer, Martina; Maushagen, Regina; Schmuckli-Maurer, Jacqueline; Bütikofer, Peter; Langsley, Gordon; Dobbelaere, Dirk, (2010). Characterisation of gp34, a GPI-anchored protein expressed by schizonts of Theileria parva and T. annulata. Molecular and biochemical parasitology, 172(2), pp. 113-20. Amsterdam: Elsevier 10.1016/j.molbiopara.2010.03.018

Bütikofer, Peter; Greganova, Eva; Liu, Yuk-Chien; Edwards, Ian J; Lehane, Michael J; Acosta-Serrano, Alvaro (2010). Lipid remodelling of glycosylphosphatidylinositol (GPI) glycoconjugates in procyclic-form trypanosomes: biosynthesis and processing of GPIs revisited. Biochemical journal, 428(3), pp. 409-18. London: Portland Press 10.1042/BJ20100229

Greganova, E; Buetikofer, P; Acosta Serrano, A (2010). The lipid portion of protease resistant surface glycoconjugate from Trypanosoma congolense is composed of triacylated phosphatidylinositol lipids and contains myristate. Molecular and biochemical parasitology, 2010(171), pp. 50-54. Amsterdam: Elsevier

Kronenberg, Daniel; Bruns, Bernd C; Moali, Catherine; Vadon-Le Goff, Sandrine; Sterchi, Erwin E; Traupe, Heiko; Böhm, Markus; Hulmes, David J S; Stöcker, Walter; Becker-Pauly, Christoph (2010). Processing of procollagen III by meprins: new players in extracellular matrix assembly? Journal of Investigative Dermatology, 130(12), pp. 2727-35. New York, N.Y.: Nature Publishing 10.1038/jid.2010.202

Bruning, M; Kreplak, L; Leopoldseder, S; Müller, SA; Tingler, P; Duchesne, L; Ferning, DG; Engel, A; Ucurum-Fotiadis, Z; Mayans, O (2010). Biparte Design of a Self-Fibrillating Protein Copolymer with Nanopatterned Peptide Display Capabilites. Nano letters, 10(11)(Nov 2010), pp. 4533-4537. Washington, D.C.: American Chemical Society 10.1021/nl1024886

Dutzler, Raimund; Ernstb, Beat; Hediger, Matthias A; Keppler, Dietrich; Mohr, Peter; Neidhart, Werner; Märki, Hans Peter (2010). Channels and transporters. Mini-symposium of the Division of Medicinal Chemistry (DMC) of the Swiss Chemical Society (SCS) at the Department of Chemistry, University of Basel, May 27, 2010. CHIMIA, 64(9), pp. 662-6. Bern: Schweizerische Chemische Gesellschaft

Luethi, Erika; Nguyen, Kong T; Bürzle, Marc; Blum, Lorenz C; Suzuki, Yoshiro; Hediger, Matthias; Reymond, Jean-Louis (2010). Identification of selective norbornane-type aspartate analogue inhibitors of the glutamate transporter 1 (GLT-1) from the chemical universe generated database (GDB). Journal of medicinal chemistry, 53(19), pp. 7236-50. Easton, Pa.: American Chemical Society 10.1021/jm100959g

Lieben, L; Benn, B S; Ajibade, D; Stockmans, I; Moermans, K; Hediger, M A; Peng, J B; Christakos, S; Bouillon, R; Carmeliet, G (2010). Trpv6 mediates intestinal calcium absorption during calcium restriction and contributes to bone homeostasis. Bone, 47(2), pp. 301-8. New York, N.Y.: Elsevier 10.1016/j.bone.2010.04.595

Baur, Roland; Lüscher, Benjamin P; Richter, Lars; Sigel, Erwin (2010). A residue close to ?1 loop F disrupts modulation of GABAA receptors by benzodiazepines while their binding is maintained. Journal of neurochemistry, 115(6), pp. 1478-85. Oxford: Wiley-Blackwell 10.1111/j.1471-4159.2010.07052.x

Rufener, Lucien; Baur, Roland; Kaminsky, Ronald; Mäser, Pascal; Sigel, Erwin (2010). Monepantel allosterically activates DEG-3/DES-2 channels of the gastrointestinal nematode Haemonchus contortus. Molecular pharmacology, 78(5), pp. 895-902. Bethesda, Md.: American Society for Pharmacology and Experimental Therapeutics 10.1124/mol.110.066498

Baur, Roland; Kaur, Kuldeep H; Sigel, Erwin (2010). Diversity of structure and function of alpha1alpha6beta3delta GABAA receptors: comparison with alpha1beta3delta and alpha6beta3delta receptors. Journal of biological chemistry, 285(23), pp. 17398-405. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M110.108670

Kopp, Sascha; Baur, Roland; Sigel, Erwin; Möhler, Hanns; Altmann, Karl-Heinz (2010). Highly potent modulation of GABA(A) receptors by valerenic acid derivatives. ChemMedChem, 5(5), pp. 678-81. Weinheim: Wiley-VCH 10.1002/cmdc.201000062

Minier, F; Sigel, E (2010). Ligand-Operated Membrane Channels:GABA. In: Elsevier, Oxford (ed.) Encyclopedia of Biological Chemistry (W.J. Lennarz and M.C.Lade, eds). Amsterdam: Elsevier

Sigel, E (2010). Microinjection into Xenopus oocytes. In: John Wiley & Sons Ltd, Chichester (ed.) Encyclopedia of Life Sciences 2010. Chichester: John Wiley & Sons Ltd, Chichester

Dietrich, Silvia Anthoine; Riediker, Linda; Gertsch, Jürg; Altmann, Karl-Heinz (2010). Synthesis and biological activity of new functionalized epothilones for prodrug design and tumor targeting. CHIMIA, 64(3), pp. 136-9. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2010.136

Altmann, Karl-Heinz; Cachoux, Frédéric; Feyen, Fabian; Gertsch, Jürg; Kuzniewski, Christian N; Wartmann, Markus (2010). Natural products as leads for anticancer drug discovery: discovery of new chemotypes of microtubule stabilizers through reengineering of the epothilone scaffold. CHIMIA, 64(1-2), pp. 8-13. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2010.8

Gertsch, Jürg; Pertwee, Roger G; Di Marzo, Vincenzo (2010). Phytocannabinoids beyond the Cannabis plant - do they exist? British journal of pharmacology, 160(3), pp. 523-9. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2010.00745.x

De Simone, Filippo; Gertsch, Jürg; Waser, Jérôme (2010). Catalytic selective cyclizations of aminocyclopropanes: formal synthesis of aspidospermidine and total synthesis of goniomitine. Angewandte Chemie (International ed.), 49(33), pp. 5767-70. Weinheim: Wiley-VCH 10.1002/anie.201001853

Leonti, Marco; Casu, Laura; Solinas, Maria Novella; Cottiglia, Filippo; Caboni, Pierluigi; Floris, Costantino; Gertsch, Juerg; Saba, Anna Rita (2010). A chromone from Seseli praecox (Apiaceae). Natural product communications, 5(4), pp. 551-4. Westerville, Ohio: Natural Product Communications NPC

Erdélyi, Máté; Navarro-Vázquez, Armando; Pfeiffer, Bernhard; Kuzniewski, Christian N; Felser, Andrea; Widmer, Toni; Gertsch, Jürg; Pera, Benet; Díaz, José Fernando; Altmann, Karl-Heinz; Carlomagno, Teresa (2010). The binding mode of side chain- and C3-modified epothilones to tubulin. ChemMedChem, 5(6), pp. 911-920. Weinheim: Wiley-VCH 10.1002/cmdc.201000050

Zurwerra, Didier; Gertsch, Jürg; Altmann, Karl-Heinz (2010). Synthesis of (-)-dactylolide and 13-desmethylene-(-)-dactylolide and their effects on tubulin. Organic letters, 12(10), pp. 2302-5. Washington, D.C.: American Chemical Society 10.1021/ol100665m

Nievergelt, Andreas; Huonker, Peter; Schoop, Roland; Altmann, Karl-Heinz; Gertsch, Jürg (2010). Identification of serotonin 5-HT1A receptor partial agonists in ginger. Bioorganic & medicinal chemistry, 18(9), pp. 3345-51. Amsterdam: Elsevier 10.1016/j.bmc.2010.02.062

Leonti, Marco; Casu, Laura; Gertsch, Jürg; Bonsignore, Leonardo; Floris, Costantino; Casu, Mariano; Cottiglia, Filippo (2010). A pterocarpan from the seeds of Bituminaria morisiana. Journal of natural medicines, 64(3), pp. 354-7. Tōkyō: Springer 10.1007/s11418-010-0408-7

Shwe, Htay Htay; Aye, Mye; Sein, Myint Myint; Htay, Khin Than; Kreitmeier, Peter; Gertsch, Jürg; Reiser, Oliver; Heilmann, Jörg (2010). Cytotoxic steroidal saponins from the rhizomes of Tacca integrifolia. Chemistry & Biodiversity, 7(3), pp. 610-22. Zürich: Verlag Helvetica Chimica Acta

Leonti, Marco; Casu, Laura; Raduner, Stefan; Cottiglia, Filippo; Floris, Costantino; Altmann, Karl-Heinz; Gertsch, Jürg (2010). Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin. Biochemical pharmacology, 79(12), pp. 1815-26. New York, N.Y.: Elsevier 10.1016/j.bcp.2010.02.015

Wullschleger, Christoph W; Gertsch, Jürg; Altmann, Karl-Heinz (2010). Stereoselective synthesis of a monocyclic peloruside a analogue. Organic letters, 12(5), pp. 1120-3. Washington, D.C.: American Chemical Society 10.1021/ol100123p

Peng, Jiangnan; Kudrimoti, Sucheta; Prasanna, Sivaprakasam; Odde, Srinivas; Doerksen, Robert J; Pennaka, Hari K; Choo, Yeun-Mun; Rao, Karumanchi V; Tekwani, Babu L; Madgula, Vamsi; Khan, Shabana I; Wang, Bin; Mayer, Alejandro M S; Jacob, Melissa R; Tu, Lan Chun; Gertsch, Jürg; Hamann, Mark T (2010). Structure-activity relationship and mechanism of action studies of manzamine analogues for the control of neuroinflammation and cerebral infections. Journal of medicinal chemistry, 53(1), pp. 61-76. Easton, Pa.: American Chemical Society

Greganova, E; Heller, M; Bütikofer, P (2010). A structural domain mediates attachment of ethanolamine phosphoglycerol to eukaryotic elongation factor 1A in Trypanosoma brucei. PLoS ONE, 5(3), e9486. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0009486

Kempna, Petra; Ricciarelli, Roberta; Azzi, Angelo; Zingg, Jean-Marc (2010). Alternative splicing and gene polymorphism of the human TAP3/SEC14L4 gene. Molecular Biology Reports, 37(7), pp. 3503-3508. Springer 10.1007/s11033-009-9943-2


Peinelt, Christine; Beck, Andreas; Monteilh-Zoller, Mahealani K; Penner, Reinhold; Fleig, Andrea (2009). IP(3) receptor subtype-dependent activation of store-operated calcium entry through I(CRAC). Cell calcium, 45(4), pp. 326-330. Elsevier 10.1016/j.ceca.2008.12.001

Wiedemann, S; Lutz, B; Albrecht, C; Kuehn, R; Killermann, B; Einspanier, R; Meyer, H.H.D. (2009). Fate of genetically modified maize and conventional rapeseed, and endozoochory in wild boar (Sus scrofa). Mammalian biology, 3(74), pp. 191-197. München: Elsevier 10.1016/j.mambio.2008.07.002

Shedova, E; Albrecht, C; Zverlov, V.V.; Schwarz, W.H. (2009). Stimulation of bacterial DNA transformation by cattle saliva: implications for using genetically modified plants in animal feed. World journal of microbiology & biotechnology, 3(25), 457-463 [7 page(s) (article)] (3/4 p.). Oxford: Springer 10.1007/s11274-008-9910-4

Gertsch, Jürg; Meier, Sarah; Müller, Martin; Altmann, Karl-Heinz (2009). Differential effects of natural product microtubule stabilizers on microtubule assembly: single agent and combination studies with taxol, epothilone B, and discodermolide. ChemBioChem, 10(1), pp. 166-75. Weinheim: Wiley-VCH 10.1002/cbic.200800556

Banerjee, S; Oneda, B; Yap, L M; Jewell, D P; Matters, G L; Fitzpatrick, L R; Seibold, F; Sterchi, E E; Ahmad, T; Lottaz, D; Bond, J S (2009). MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease. Mucosal immunology, 2(3), pp. 220-31. New York, N.Y.: Nature Publishing Group 10.1038/mi.2009.3

Signorell, Aita; Gluenz, Eva; Rettig, Jochen; Schneider, André; Shaw, Michael; Gull, Keith; Bütikofer, Peter (2009). Perturbation of phosphatidylethanolamine synthesis affects mitochondrial morphology and cell-cycle progression in procyclic-form Trypanosoma brucei. Molecular microbiology, 72(4), pp. 1068-79. Oxford: Blackwell Science 10.1111/j.1365-2958.2009.06713.x

Vassella, Erik; Oberle, Michael; Urwyler, Simon; Renggli, Christina Kunz; Studer, Erwin; Hemphill, Andrew; Fragoso, Cristina; Bütikofer, Peter; Brun, Reto; Roditi, Isabel (2009). Major surface glycoproteins of insect forms of Trypanosoma brucei are not essential for cyclical transmission by tsetse. PLoS ONE, 4(2), e4493. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0004493

Passarella, Daniele; Comi, Daniela; Cappelletti, Graziella; Cartelli, Daniele; Gertsch, Juerg; Quesada, Ana R; Borlak, Jurgen; Altmann, Karl-Heinz (2009). Synthesis and biological evaluation of epothilone A dimeric compounds. Bioorganic & medicinal chemistry, 17(21), pp. 7435-40. Amsterdam: Elsevier 10.1016/j.bmc.2009.09.032

Dietrich, Silvia Anthoine; Lindauer, Renate; Stierlin, Claire; Gertsch, Jürg; Matesanz, Ruth; Notararigo, Sara; Díaz, José Fernando; Altmann, Karl-Heinz (2009). Epothilone analogues with benzimidazole and quinoline side chains: chemical synthesis, antiproliferative activity, and interactions with tubulin. Chemistry - a European journal, 15(39), pp. 10144-57. Weinheim: Wiley-VCH 10.1002/chem.200901376

Oesch, Susanne; Gertsch, Jürg (2009). Cannabinoid receptor ligands as potential anticancer agents--high hopes for new therapies? Journal of pharmacy and pharmacology, 61(7), pp. 839-53. London: Royal Pharmaceutical Society of Great Britain 10.1211/jpp/61.07.0002

Pfeiffer, Bernhard; Hauenstein, Kurt; Merz, Philipp; Gertsch, Jürg; Altmann, Karl-Heinz (2009). Synthesis and SAR of C12-C13-oxazoline derivatives of epothilone A. Bioorganic and medicinal chemistry letters, 19(14), pp. 3760-3. New York, N.Y.: Pergamon 10.1016/j.bmcl.2009.04.112

Gollner, Andreas; Altmann, Karl-Heinz; Gertsch, Jürg; Mulzer, Johann (2009). The laulimalide family: total synthesis and biological evaluation of neolaulimalide, isolaulimalide, laulimalide and a nonnatural analogue. Chemistry - a European journal, 15(24), pp. 5979-97. Weinheim: Wiley-VCH 10.1002/chem.200802605

Chicca, Andrea; Raduner, Stefan; Pellati, Federica; Strompen, Thomas; Altmann, Karl-Heinz; Schoop, Roland; Gertsch, Jürg (2009). Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts. International immunopharmacology, 9(7-8), pp. 850-8. Amsterdam: Elsevier 10.1016/j.intimp.2009.03.006

Gertsch, Jürg (2009). How scientific is the science in ethnopharmacology? Historical perspectives and epistemological problems. Journal of ethnopharmacology, 122(2), pp. 177-83. Shannon: Elsevier Science Ireland 10.1016/j.jep.2009.01.010

Markt, Patrick; Feldmann, Clemens; Rollinger, Judith Maria; Raduner, Stefan; Schuster, Daniela; Kirchmair, Johannes; Distinto, Simona; Spitzer, Gudrun Maria; Wolber, Gerhard; Laggner, Christian; Altmann, Karl-Heinz; Langer, Thierry; Gertsch, Jürg (2009). Discovery of novel CB2 receptor ligands by a pharmacophore-based virtual screening workflow. Journal of medicinal chemistry, 52(2), pp. 369-78. Easton, Pa.: American Chemical Society 10.1021/jm801044g

Rollinger, Judith M; Schuster, Daniela; Danzl, Birgit; Schwaiger, Stefan; Markt, Patrick; Schmidtke, Michaela; Gertsch, Jürg; Raduner, Stefan; Wolber, Gerhard; Langer, Thierry; Stuppner, Hermann (2009). In silico target fishing for rationalized ligand discovery exemplified on constituents of Ruta graveolens. Planta medica, 75(3), pp. 195-204. Stuttgart: Thieme 10.1055/s-0028-1088397

Gertsch, Jürg; Feyen, Fabian; Bützberger, Alexander; Gerber, Barbara; Pfeiffer, Bernhard; Altmann, Karl-Heinz (2009). Making epothilones fluoresce: design, synthesis, and biological characterization of a fluorescent N12-aza-epothilone (azathilone). ChemBioChem, 10(15), pp. 2513-21. Weinheim: Wiley-VCH 10.1002/cbic.200900376

Casagrande, Fabio; Harder, Daniel; Schenk, Andreas; Meury, Marcel; Ucurum, Zohre; Engel, Andreas; Weitz, Dietmar; Daniel, Hannelore; Fotiadis, Dimitrios (2009). Projection structure of DtpD (YbgH), a prokaryotic member of the peptide transporter family. Journal of molecular biology, 394(4), pp. 708-17. Amsterdam: Elsevier 10.1016/j.jmb.2009.09.048

Bippes, Christian A; Zeltina, Antra; Casagrande, Fabio; Ratera, Merce; Palacin, Manuel; Muller, Daniel J; Fotiadis, Dimitrios (2009). Substrate binding tunes conformational flexibility and kinetic stability of an amino acid antiporter. Journal of biological chemistry, 284(28), pp. 18651-63. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M109.004267

Jastrzebska, Beata; Golczak, Marcin; Fotiadis, Dimitrios; Engel, Andreas; Palczewski, Krzysztof (2009). Isolation and functional characterization of a stable complex between photoactivated rhodopsin and the G protein, transducin. FASEB journal, 23(2), pp. 371-81. Bethesda, Md.: Federation of American Societies for Experimental Biology 10.1096/fj.07-114835

Bolanz, Katrin A; Kovacs, Gergely Gy; Landowski, Christopher P; Hediger, Matthias A (2009). Tamoxifen inhibits TRPV6 activity via estrogen receptor-independent pathways in TRPV6-expressing MCF-7 breast cancer cells. Molecular cancer research, 7(12), pp. 2000-10. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1541-7786.MCR-09-0188

Sigel, Erwin; Kaur, Kuldeep H; Lüscher, Benjamin P; Baur, Roland (2009). Use of concatamers to study GABAA receptor architecture and function: application to delta-subunit-containing receptors and possible pitfalls. Biochemical Society transactions, 37(Pt 6), pp. 1338-42. London: Portland Press 10.1042/BST0371338

Tan, Kelly R; Baur, Roland; Charon, Sébastien; Goeldner, Maurice; Sigel, Erwin (2009). Relative positioning of diazepam in the benzodiazepine-binding-pocket of GABA receptors. Journal of neurochemistry, 111(5), pp. 1264-73. Oxford: Wiley-Blackwell 10.1111/j.1471-4159.2009.06419.x

Baur, Roland; Kaur, Kuldeep H; Sigel, Erwin (2009). Structure of alpha6 beta3 delta GABA(A) receptors and their lack of ethanol sensitivity. Journal of neurochemistry, 111(5), pp. 1172-81. Oxford: Wiley-Blackwell 10.1111/j.1471-4159.2009.06387.x

Kaur, Kuldeep H; Baur, Roland; Sigel, Erwin (2009). Unanticipated structural and functional properties of delta-subunit-containing GABAA receptors. Journal of biological chemistry, 284(12), pp. 7889-96. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M806484200

Nichols, Buford L; Quezada-Calvillo, Roberto; Robayo-Torres, Claudia C; Ao, Zihua; Hamaker, Bruce R; Butte, Nancy F; Marini, Juan; Jahoor, Farook; Sterchi, Erwin E (2009). Mucosal maltase-glucoamylase plays a crucial role in starch digestion and prandial glucose homeostasis of mice. Journal of nutrition, 139(4), pp. 684-90. Bethesda, Md.: American Society for Nutrition 10.3945/jn.108.098434

Bergeron, Marc J; Frenette-Cotton, Rachelle; Carpentier, Gabriel A; Simard, Michael G; Caron, Luc; Isenring, Paul (2009). Phosphoregulation of K(+)-Cl(-) cotransporter 4 during changes in intracellular Cl(-) and cell volume. Journal of cellular physiology, 219(3), pp. 787-96. Hoboken, N.J.: Wiley 10.1002/jcp.21725

Wächter, Regula; Masarik, Lukas; Bürzle, Marc; Mallik, Ajit; von Mandach, Ursula (2009). Differential expression and activity of 11beta-hydroxysteroid dehydrogenase in human placenta and fetal membranes from pregnancies with intrauterine growth restriction. Fetal diagnosis and therapy, 25(3), pp. 328-35. Basel: Karger 10.1159/000235879

Gollner, A; Altmann, K.-H; Gertsch, J; Mulzer, J (2009). Synthesis and biological evaluation of a des-dihydropyran laulimalide analog. Tetrahedron letters, 50(42), pp. 5790-5792. Amsterdam: Elsevier 10.1016/j.tetlet.2009.07.122

Guertler, Patrick; Paul, Vijay; Albrecht, Christiane; Meyer, Heinrich H D (2009). Sensitive and highly specific quantitative real-time PCR and ELISA for recording a potential transfer of novel DNA and Cry1Ab protein from feed into bovine milk. Analytical and bioanalytical chemistry, 393(6-7), pp. 1629-38. Heidelberg: Springer 10.1007/s00216-009-2667-2

Mani, O; Sorensen, M T; Sejrsen, K; Bruckmaier, R M; Albrecht, C (2009). Differential expression and localization of lipid transporters in the bovine mammary gland during the pregnancy-lactation cycle. Journal of dairy science, 92(8), pp. 3744-56. Savoy, Ill.: American Dairy Science Association 10.3168/jds.2009-2063


Peinelt, Christine; Lis, Annette; Beck, Andreas; Fleig, Andrea; Penner, Reinhold (2008). 2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels. Journal of physiology, 586(13), pp. 3061-3073. Wiley-Blackwell 10.1113/jphysiol.2008.151365

Parvez, Suhel; Beck, Andreas; Peinelt, Christine; Soboloff, Jonathan; Lis, Annette; Monteilh-Zoller, Mahealani; Gill, Donald L; Fleig, Andrea; Penner, Reinhold (2008). STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation. FASEB journal, 22(3), pp. 752-761. Federation of American Societies for Experimental Biology 10.1096/fj.07-9449com

Bollan, Karen A; Baur, Roland; Hales, Tim G; Sigel, Erwin; Connolly, Christopher N (2008). The promiscuous role of the epsilon subunit in GABA(A) receptor biogenesis. Molecular and cellular neuroscience, 37(3), pp. 610-621. San Diego, Calif.: Elsevier 10.1016/j.mcn.2007.12.011

Niggli, Verena; Sigel, Erwin (2008). Anticipating antiport in P-type ATPases. Trends in biochemical sciences, 33(4), pp. 156-60. Cambridge: Elsevier Current Trends 10.1016/j.tibs.2007.12.005

Farke, Carolin; Meyer, Heinrich H D; Bruckmaier, Rupert M; Albrecht, Christiane (2008). Differential expression of ABC transporters and their regulatory genes during lactation and dry period in bovine mammary tissue. Journal of dairy research, 75(4), pp. 406-14. London: Cambridge University Press 10.1017/S002202990800335X

Paul, Vijay; Meyer Heinrich, H D; Leidl, Katharina; Soumian, Soni; Albrecht, Christiane (2008). A novel enzyme immunoassay specific for ABCA1 protein quantification in human tissues and cells. Journal of lipid research, 49(10), pp. 2259-67. Bethesda, Md.: American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.D700040-JLR200

Gürtler, P; Lutz, B; Kühn, R; Meyer, H.H.D.; Albrecht, C (2008). Fate of recombinant DNA and Cry1Ab protein after ingestion and dispersal of genetically modified maize in comparison to rapeseed by fallow deer (Dama dama). European journal of wildlife research, 54(2008), pp. 36-43. Berlin: Springer-Verlag 10.1007/s10344-007-0104-4

Casagrande, Fabio; Ratera, Merce; Schenk, Andreas D; Chami, Mohamed; Valencia, Eva; Lopez, Jesus Maria; Torrents, David; Engel, Andreas; Palacin, Manuel; Fotiadis, Dimitrios (2008). Projection structure of a member of the amino acid/polyamine/organocation transporter superfamily. Journal of biological chemistry, 283(48), pp. 33240-8. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M806917200

Harder, Daniel; Stolz, Jürgen; Casagrande, Fabio; Obrdlik, Petr; Weitz, Dietmar; Fotiadis, Dimitrios; Daniel, Hannelore (2008). DtpB (YhiP) and DtpA (TppB, YdgR) are prototypical proton-dependent peptide transporters of Escherichia coli. FEBS journal, 275(13), pp. 3290-8. Oxford: Wiley-Blackwell 10.1111/j.1742-4658.2008.06477.x

Whorton, Matthew R; Jastrzebska, Beata; Park, Paul S-H; Fotiadis, Dimitrios; Engel, Andreas; Palczewski, Krzysztof; Sunahara, Roger K (2008). Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer. Journal of biological chemistry, 283(7), pp. 4387-94. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M703346200

Hoogenboom, B.W.; Frederix, P.L.T.M.; Fotiadis, D (2008). Potential of interferometric cantilever detection and its application for SFM/AFM in liquids. Nanotechnology, 19(38), p. 384019. Bristol, UK: Institute of Physics Publishing IOP 10.1088/0957-4484/19/38/384019

Bosshart, P.D.; Casagrande, F; Frederix, P.L.T.M.; Ratera, M; Bippes, C.A.; Müller, D.J.; Palacin, M; Engel, A; Fotiadis, D (2008). High-throughput single-molecule force spectroscopy for membrane proteins. Nanotechnology, 19(38), p. 384014. Bristol, UK: Institute of Physics Publishing IOP 10.1088/0957-4484/19/38/384014

Goldshmidt, Hanoch; Sheiner, Lilach; Bütikofer, Peter; Roditi, Isabel; Uliel, Shai; Günzel, Mark; Engstler, Markus; Michaeli, Shulamit (2008). Role of protein translocation pathways across the endoplasmic reticulum in Trypanosoma brucei. Journal of biological chemistry, 283(46), pp. 32085-32098. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M801499200

Signorell, Aita; Rauch, Monika; Jelk, Jennifer; Ferguson, Michael A J; Bütikofer, Peter (2008). Phosphatidylethanolamine in Trypanosoma brucei is organized in two separate pools and is synthesized exclusively by the Kennedy pathway. Journal of biological chemistry, 283(35), pp. 23636-44. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M803600200

Signorell, Aita; Jelk, Jennifer; Rauch, Monika; Bütikofer, Peter (2008). Phosphatidylethanolamine is the precursor of the ethanolamine phosphoglycerol moiety bound to eukaryotic elongation factor 1A. Journal of biological chemistry, 283(29), pp. 20320-9. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M802430200

Jaquenoud, Malika; Pagac, Martin; Signorell, Aita; Benghezal, Mohammed; Jelk, Jennifer; Bütikofer, Peter; Conzelmann, Andreas (2008). The Gup1 homologue of Trypanosoma brucei is a GPI glycosylphosphatidylinositol remodelase. Molecular microbiology, 67(1), pp. 202-12. Oxford: Blackwell Science 10.1111/j.1365-2958.2007.06043.x

Sterchi, Erwin E (2008). Special issue: metzincin metalloproteinases. Molecular aspects of medicine, 29(5), pp. 255-7. Amsterdam: Elsevier 10.1016/j.mam.2008.08.007

Ambort, Daniel; Lottaz, Daniel; Sterchi, Erwin (2008). Sample preparation of culture medium from Madin-Darby canine kidney cells. Methods in molecular biology, 425, pp. 113-130. Totowa, N.J.: Humana Press

Sterchi, Erwin E; Stöcker, Walter; Bond, Judith S (2008). Meprins, membrane-bound and secreted astacin metalloproteinases. Molecular aspects of medicine, 29(5), pp. 309-28. Amsterdam: Elsevier 10.1016/j.mam.2008.08.002

Bergin, David A; Greene, Catherine M; Sterchi, Erwin E; Kenna, Cliona; Geraghty, Patrick; Belaaouaj, Abderazzaq; Taggart, Clifford C; O'Neill, Shane J; McElvaney, Noel G (2008). Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway. Journal of biological chemistry, 283(46), pp. 31736-44. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M803732200

Ambort, Daniel; Stalder, Daniel; Lottaz, Daniel; Huguenin, Maya; Oneda, Beatrice; Heller, Manfred; Sterchi, Erwin E (2008). A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin. FEBS journal, 275(18), pp. 4490-509. Oxford: Wiley-Blackwell 10.1111/j.1742-4658.2008.06592.x

Oneda, Beatrice; Lods, Nadège; Lottaz, Daniel; Becker-Pauly, Christoph; Stöcker, Walter; Pippin, Jeffrey; Huguenin, Maya; Ambort, Daniel; Marti, Hans-Peter; Sterchi, Erwin E (2008). Metalloprotease meprin beta in rat kidney: glomerular localization and differential expression in glomerulonephritis. PLoS ONE, 3(5), e2278. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0002278

Huguenin, Maya; Müller, Eliane J; Trachsel-Rösmann, Sandra; Oneda, Beatrice; Ambort, Daniel; Sterchi, Erwin E; Lottaz, Daniel (2008). The metalloprotease meprinbeta processes E-cadherin and weakens intercellular adhesion. PLoS ONE, 3(5), e2153. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0002153

Quezada-Calvillo, Roberto; Sim, Lyann; Ao, Zihua; Hamaker, Bruce R; Quaroni, Andrea; Brayer, Gary D; Sterchi, Erwin E; Robayo-Torres, Claudia C; Rose, David R; Nichols, Buford L (2008). Luminal starch substrate "brake" on maltase-glucoamylase activity is located within the glucoamylase subunit. Journal of nutrition, 138(4), pp. 685-92. Bethesda, Md.: American Society for Nutrition

Sim, Lyann; Quezada-Calvillo, Roberto; Sterchi, Erwin E; Nichols, Buford L; Rose, David R (2008). Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity. Journal of molecular biology, 375(3), pp. 782-92. Amsterdam: Elsevier 10.1016/j.jmb.2007.10.069

Burgunder, Jean-Marc; Huifang, Shang; Beguin, Pascal; Baur, Roland; Eng, Chew Soh; Seet, Raymond C S; Lim, Erle C H; Ong, Benjamin K C; Hunziker, Walter; Sigel, Erwin (2008). Novel chloride channel mutations leading to mild myotonia among Chinese. Neuromuscular disorders, 18(8), pp. 633-40. Amsterdam: Elsevier 10.1016/j.nmd.2008.05.007

Baur, Roland; Tan, Kelly R; Lüscher, Benjamin P; Gonthier, Anne; Goeldner, Maurice; Sigel, Erwin (2008). Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs. Journal of neurochemistry, 106(6), pp. 2353-63. Oxford: Wiley-Blackwell 10.1111/j.1471-4159.2008.05574.x

Sung, Ji-Min; Cho, Hee-Jung; Yi, Hee; Lee, Chi-Ho; Kim, Hye-Sun; Kim, Dong-Ku; Abd El-Aty, A M; Kim, Jin-Suk; Landowski, Christopher P; Hediger, Matthias A; Shin, Ho-Chul (2008). Characterization of a stem cell population in lung cancer A549 cells. Biochemical and biophysical research communications, 371(1), pp. 163-7. Orlando, Fla.: Academic Press 10.1016/j.bbrc.2008.04.038

Bergeron, M; Simonin, A; Bürzle, M; Hediger, M (2008). Inherited epithelial transporter disorders-an overview. Journal of inherited metabolic disease, 31(2), pp. 178-187. Lancaster, UK: Springer Netherlands 10.1007/s10545-008-0861-6

Suzuki, Yoshiro; Kovacs, Christopher S; Takanaga, Hitomi; Peng, Ji-Bin; Landowski, Christopher P; Hediger, Matthias A (2008). Calcium channel TRPV6 is involved in murine maternal-fetal calcium transport. Journal of bone and mineral research, 23(8), pp. 1249-56. Hoboken, N.J.: Wiley-Blackwell 10.1359/JBMR.080314

Suzuki, Yoshiro; Pasch, Andreas; Bonny, Olivier; Mohaupt, Markus G; Hediger, Matthias A; Frey, Felix J (2008). Gain-of-function haplotype in the epithelial calcium channel TRPV6 is a risk factor for renal calcium stone formation. Human molecular genetics, 17(11), pp. 1613-8. Oxford: Oxford University Press 10.1093/hmg/ddn048

Bolanz, Katrin A; Hediger, Matthias A; Landowski, Christopher P (2008). The role of TRPV6 in breast carcinogenesis. Molecular cancer therapeutics, 7(2), pp. 271-9. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1535-7163.MCT-07-0478

Mackenzie, Bryan; Illing, Anthony C; Hediger, Matthias A (2008). Transport model of the human Na+-coupled L-ascorbic acid (vitamin C) transporter SVCT1. American journal of physiology - cell physiology, 294(2), C451-9. Bethesda, Md.: American Physiological Society 10.1152/ajpcell.00439.2007

Suzuki, Yoshiro; Landowski, Christopher P; Hediger, Matthias A (2008). Mechanisms and regulation of epithelial Ca2+ absorption in health and disease. Annual review of physiology, 70, pp. 257-271. Palo Alto, Calif.: Annual Reviews Inc. 10.1146/annurev.physiol.69.031905.161003

Benn, Bryan S; Ajibade, Dare; Porta, Angela; Dhawan, Puneet; Hediger, Matthias; Peng, Ji-Bin; Jiang, Yi; Oh, Goo Taeg; Jeung, Eui-Bae; Lieben, Liesbet; Bouillon, Roger; Carmeliet, Geert; Christakos, Sylvia (2008). Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k. Endocrinology, 149(6), pp. 3196-205. Chevy Chase, Md.: Endocrine Society 10.1210/en.2007-1655

Schütz, Patrick; Bumann, Mario; Oberholzer, Anselm Erich; Bieniossek, Christoph; Trachsel, Hans; Altmann, Michael; Baumann, Ulrich (2008). Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein-protein interactions. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 105(28), pp. 9564-9569. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.0800418105

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Gertsch, Jürg; Leonti, Marco; Raduner, Stefan; Racz, Ildiko; Chen, Jian-Zhong; Xie, Xiang-Qun; Altmann, Karl-Heinz; Karsak, Meliha; Zimmer, Andreas (2008). Beta-caryophyllene is a dietary cannabinoid. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 105(26), pp. 9099-104. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.0803601105

Kuzniewski, Christian N; Gertsch, Jürg; Wartmann, Markus; Altmann, Karl-Heinz (2008). Total synthesis of hypermodified epothilone analogs with potent in vitro antitumor activity. Organic letters, 10(6), pp. 1183-6. Washington, D.C.: American Chemical Society 10.1021/ol800089x

Gertsch, Jürg (2008). Immunomodulatory lipids in plants: plant fatty acid amides and the human endocannabinoid system. Planta medica, 74(6), pp. 638-50. Stuttgart: Thieme 10.1055/s-2008-1034302

Erdélyi, Máté; Pfeiffer, Bernhard; Hauenstein, Kurt; Fohrer, Jörg; Gertsch, Jürg; Altmann, Karl-Heinz; Carlomagno, Teresa (2008). Conformational preferences of natural and C3-modified epothilones in aqueous solution. Journal of medicinal chemistry, 51(5), pp. 1469-73. Easton, Pa.: American Chemical Society 10.1021/jm7013452

Hamel, Cotinica; Prusov, Evgeny V; Gertsch, Jürg; Schweizer, W Bernd; Altmann, Karl-Heinz (2008). Total synthesis of the marine diterpenoid blumiolide C. Angewandte Chemie (International ed.), 47(52), pp. 10081-5. Weinheim: Wiley-VCH 10.1002/anie.200804004

Collu, Francesca; Bonsignore, Leonardo; Casu, Mariano; Floris, Costantino; Gertsch, Jürg; Cottiglia, Filippo (2008). New cytotoxic saturated and unsaturated cyclohexanones from Anthemis maritima. Bioorganic and medicinal chemistry letters, 18(5), pp. 1559-62. New York, N.Y.: Pergamon 10.1016/j.bmcl.2008.01.078

Feyen, Fabian; Cachoux, Frédéric; Gertsch, Jürg; Wartmann, Markus; Altmann, Karl-Heinz (2008). Epothilones as lead structures for the synthesis-based discovery of new chemotypes for microtubule stabilization. Accounts of chemical research, 41(1), pp. 21-31. Easton, Pa.: American Chemical Society 10.1021/ar700157x


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Arechaga, Ignacio; Fotiadis, Dimitrios (2007). Reconstitution of mitochondrial ATP synthase into lipid bilayers for structural analysis. Journal of structural biology, 160(3), pp. 287-94. San Diego, Calif.: Elsevier 10.1016/j.jsb.2007.09.007

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Mackenzie, Bryan; Takanaga, Hitomi; Hubert, Nadia; Rolfs, Andreas; Hediger, Matthias A (2007). Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1). Biochemical journal, 403(1), pp. 59-69. London: Portland Press 10.1042/BJ20061290

Tan, Kelly R; Baur, Roland; Gonthier, Anne; Goeldner, Maurice; Sigel, Erwin (2007). Two neighboring residues of loop A of the alpha1 subunit point towards the benzodiazepine binding site of GABAA receptors. FEBS letters, 581(24), pp. 4718-22. Amsterdam: Elsevier 10.1016/j.febslet.2007.08.068

Tan, Kelly R; Gonthier, Anne; Baur, Roland; Ernst, Margot; Goeldner, Maurice; Sigel, Erwin (2007). Proximity-accelerated chemical coupling reaction in the benzodiazepine-binding site of gamma-aminobutyric acid type A receptors: superposition of different allosteric modulators. Journal of biological chemistry, 282(36), pp. 26316-25. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M702153200

Baur, Roland; Sigel, Erwin (2007). Replacement of histidine in position 105 in the alpha(5) subunit by cysteine stimulates zolpidem sensitivity of alpha(5)beta(2)gamma(2) GABA(A) receptors. Journal of neurochemistry, 103(6), pp. 2556-2564. Oxford: Wiley-Blackwell 10.1111/j.1471-4159.2007.04982.x

Raduner, Stefan; Bisson, William; Abagyan, Ruben; Altmann, Karl-Heinz; Gertsch, Jürg (2007). Self-assembling cannabinomimetics: supramolecular structures of N-alkyl amides. Journal of natural products, 70(6), pp. 1010-5. Washington, D.C.: American Chemical Society 10.1021/np060598+

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Altmann, Karl-Heinz; Gertsch, Jürg (2007). Anticancer drugs from nature--natural products as a unique source of new microtubule-stabilizing agents. Natural product reports, 24(2), pp. 327-57. Cambridge: Royal Society of Chemistry 10.1039/b515619j


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Negis, Yesim; Aytan, Nurgül; Ozer, Nesrin; Ogru, Esra; Libinaki, Roksan; Gianello, Robert; Azzi, Angelo; Zingg, Jean-Marc (2006). The effect of tocopheryl phosphates on atherosclerosis progression in rabbits fed with a high cholesterol diet. Archives of biochemistry and biophysics, 450(1), pp. 63-6. San Diego, Calif.: Elsevier 10.1016/j.abb.2006.02.027

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Munteanu, Adelina; Taddei, Michele; Tamburini, Ilaria; Bergamini, Ettore; Azzi, Angelo; Zingg, Jean-Marc (2006). Antagonistic effects of oxidized low density lipoprotein and alpha-tocopherol on CD36 scavenger receptor expression in monocytes: involvement of protein kinase B and peroxisome proliferator-activated receptor-gamma. Journal of biological chemistry, 281(10), pp. 6489-97. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M508799200

Ozer, Nesrin Kartal; Negis, Yesim; Aytan, Nurgül; Villacorta, Luis; Ricciarelli, Roberta; Zingg, Jean-Marc; Azzi, Angelo (2006). Vitamin E inhibits CD36 scavenger receptor expression in hypercholesterolemic rabbits. Atherosclerosis, 184(1), pp. 15-20. Amsterdam: Elsevier 10.1016/j.atherosclerosis.2005.03.050

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