Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses.

Siddharta, Anindya; Pfänder, Stephanie; Vielle, Nathalie Jane; Dijkman, Ronald; Friesland, Martina; Becker, Britta; Yang, Jaewon; Engelmann, Michael; Todt, Daniel; Windisch, Marc P; Brill, Florian H; Steinmann, Joerg; Steinmann, Jochen; Becker, Stephan; Alves, Marco; Pietschmann, Thomas; Eickmann, Markus; Thiel, Volker Earl; Steinmann, Eike (2017). Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses. Journal of infectious diseases, 215(6), pp. 902-906. Oxford University Press 10.1093/infdis/jix046

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The World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this study, we evaluated the virucidal activity of these WHO products in a comparative analysis. Zika virus (ZIKV), Ebola virus (EBOV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) as (re-)emerging viral pathogens and other enveloped viruses could be efficiently inactivated by both WHO formulations, implicating their use in healthcare systems and viral outbreak situations.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Virology and Immunology
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction

UniBE Contributor:

Pfänder, Stephanie; Vielle, Nathalie Jane; Dijkman, Ronald; Alves, Marco and Thiel, Volker Earl

Subjects:

600 Technology > 630 Agriculture
500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

0022-1899

Publisher:

Oxford University Press

Language:

English

Submitter:

Achim Braun Parham

Date Deposited:

15 May 2018 14:38

Last Modified:

15 May 2018 14:48

Publisher DOI:

10.1093/infdis/jix046

PubMed ID:

28453839

Uncontrolled Keywords:

Ebola virus SARS WHO Zika virus MERS

BORIS DOI:

10.7892/boris.112064

URI:

https://boris.unibe.ch/id/eprint/112064

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