Siddharta, Anindya; Pfänder, Stephanie; Vielle, Nathalie Jane; Dijkman, Ronald; Friesland, Martina; Becker, Britta; Yang, Jaewon; Engelmann, Michael; Todt, Daniel; Windisch, Marc P; Brill, Florian H; Steinmann, Joerg; Steinmann, Jochen; Becker, Stephan; Alves, Marco; Pietschmann, Thomas; Eickmann, Markus; Thiel, Volker Earl; Steinmann, Eike (2017). Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses. Journal of infectious diseases, 215(6), pp. 902-906. Oxford University Press 10.1093/infdis/jix046
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The World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this study, we evaluated the virucidal activity of these WHO products in a comparative analysis. Zika virus (ZIKV), Ebola virus (EBOV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) as (re-)emerging viral pathogens and other enveloped viruses could be efficiently inactivated by both WHO formulations, implicating their use in healthcare systems and viral outbreak situations.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Virology and Immunology 05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) 05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction |
UniBE Contributor: |
Pfänder, Stephanie, Vielle, Nathalie Jane, Dijkman, Ronald, Alves, Marco, Thiel, Volker Earl |
Subjects: |
600 Technology > 630 Agriculture 500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
0022-1899 |
Publisher: |
Oxford University Press |
Language: |
English |
Submitter: |
Pamela Schumacher |
Date Deposited: |
15 May 2018 14:38 |
Last Modified: |
05 Dec 2022 15:11 |
Publisher DOI: |
10.1093/infdis/jix046 |
PubMed ID: |
28453839 |
Uncontrolled Keywords: |
Ebola virus SARS WHO Zika virus MERS |
BORIS DOI: |
10.7892/boris.112064 |
URI: |
https://boris.unibe.ch/id/eprint/112064 |
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