Bovine dilated cardiomyopathy: Almost forgotten but still present

Riedi, Anna-Katharina; Drögemüller, Cord; Gurtner, Corinne; Meylan, Mireille (2018). Bovine dilated cardiomyopathy: Almost forgotten but still present. Schweizer Archiv für Tierheilkunde, 160(5), pp. 289-293. Huber 10.17236/sat00158

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Numerous cases of bovine dilatative cardiomyopathy (BDCMP) were registered in the nineteen-eighties, but the prevalence decreased steadily thanks to classical selection measures, i.e. excluding putative carrier animals from breeding. The cases described here show that the recessively inherited disease is still present in the Swiss cattle population. By use of a direct gene test developed a few years ago, a clinical tentative diagnosis can be confirmed. Since the end of the year 2016, carriers are officially labelled as such in Switzerland. Currently, about 2% of the insemination sires of the Holstein, Red Holstein and Swiss Fleckvieh breeds carry the causative mutation in the OPA3 gene. A combination of increased awareness of the disease and use of the gene test should allow for complete elimination of the disease from the Swiss cattle population.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Clinic for Ruminants
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Animal Pathology
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Institute of Genetics
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH)

UniBE Contributor:

Riedi, Anna-Katharina; Drögemüller, Cord; Gurtner, Corinne and Meylan, Mireille

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 590 Animals (Zoology)
600 Technology > 610 Medicine & health
600 Technology > 630 Agriculture

ISSN:

0036-7281

Publisher:

Huber

Language:

German

Submitter:

Cord Drögemüller

Date Deposited:

09 May 2018 16:10

Last Modified:

11 May 2018 07:30

Publisher DOI:

10.17236/sat00158

PubMed ID:

29717982

Uncontrolled Keywords:

Gendefekt, Diagnostik Herzinsuffizienz Rind Zuchthygiene cattle diagnostics, breeding hygiene genetic defect heart failure

BORIS DOI:

10.7892/boris.116404

URI:

https://boris.unibe.ch/id/eprint/116404

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