Tumour budding is a strong and independent prognostic factor in pancreatic cancer

Karamitopoulou, Evanthia; Zlobec, I; Born, D; Kondi-Pafiti, A; Lykoudis, P; Mellou, A; Gennatas, K; Gloor, B; Lugli, A (2013). Tumour budding is a strong and independent prognostic factor in pancreatic cancer. European journal of cancer, 49(5), pp. 1032-9. Amsterdam: Elsevier 10.1016/j.ejca.2012.10.022

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Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer that escapes detection and resists treatment. Tumour budding, defined as the presence of de-differentiated single tumour cells or small cell clusters at the invasive front of gastrointestinal carcinomas like colorectal, oesophageal, gastric and ampullary, is linked to adverse prognosis. Tumour budding has not yet been reported in PDAC.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology
04 Faculty of Medicine > Service Sector > Institute of Pathology > Clinical Pathology
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Visceral Surgery

UniBE Contributor:

Karamitopoulou, Evanthia; Zlobec, Inti; Born, Diana; Gloor, Beat and Lugli, Alessandro

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

0959-8049

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:32

Last Modified:

31 Jan 2018 11:46

Publisher DOI:

10.1016/j.ejca.2012.10.022

PubMed ID:

23177090

Web of Science ID:

000315945500006

URI:

https://boris.unibe.ch/id/eprint/12478 (FactScience: 218827)

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