Zlobec, Inti; Bihl, Michel P; Foerster, Anja; Rufle, Alex; Lugli, Alessandro (2012). The impact of CpG island methylator phenotype and microsatellite instability on tumour budding in colorectal cancer. Histopathology, 61(5), pp. 777-87. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2559.2012.04273.x
Full text not available from this repository.In colorectal cancer, tumour budding, a process likened to epithelial mesenchymal transition, is an adverse prognostic factor which is rarely found in tumours with high-level microsatellite instability (MSI-H). Cases with MSI-H or high-level CpG island methylator phenotype (CIMP-H) have similar histomorphological features, yet seemingly opposite prognosis. We hypothesized that tumour budding is related to CIMP, thus partially explaining this prognostic difference.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology |
UniBE Contributor: |
Zlobec, Inti, Lugli, Alessandro |
ISSN: |
0309-0167 |
Publisher: |
Blackwell Scientific Publications |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:32 |
Last Modified: |
05 Dec 2022 14:10 |
Publisher DOI: |
10.1111/j.1365-2559.2012.04273.x |
PubMed ID: |
22803799 |
Web of Science ID: |
000310482400004 |
URI: |
https://boris.unibe.ch/id/eprint/12500 (FactScience: 218852) |
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