The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A(2) and suppress PGE(2) formation in mesangial cells

Huwiler, Andrea; Feuerherm, Astrid J; Sakem, Benjamin; Pastukhov, Oleksandr; Filipenko, Iuliia; Nguyen, Thuy; Johansen, Berit (2012). The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A(2) and suppress PGE(2) formation in mesangial cells. British journal of pharmacology, 167(8), pp. 1691-701. Oxford: Wiley-Blackwell 10.1111/j.1476-5381.2012.02114.x

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ω3-polyunsaturated fatty acids (ω3-PUFAs) are known to exert anti-inflammatory effects in various disease models although their direct targets are only poorly characterized.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Pharmacology

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Huwiler, Andrea; Pastukhov, Oleksandr and Filipenko, Iuliia

ISSN:

0007-1188

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:35

Last Modified:

13 Oct 2016 14:30

Publisher DOI:

10.1111/j.1476-5381.2012.02114.x

PubMed ID:

22831644

Web of Science ID:

000311854000012

URI:

https://boris.unibe.ch/id/eprint/14086 (FactScience: 220893)

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