Morshed, M; Yousefi, S; Stöckle, C; Simon, H-U; Simon, D (2012). Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps. Allergy, 67(9), pp. 1127-37. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2012.02868.x
Full text not available from this repository. (Request a copy)Thymic stromal lymphopoietin (TSLP) that is released by epithelial cells upon certain environmental triggers activates cells of the innate and adaptive immune system resulting in a preferential T helper 2 immune response. By releasing eosinophil extracellular traps (EETs), eosinophils achieve an efficient extracellular bacterial killing. Eosinophil extracellular traps release, however, has been observed in both infectious and noninfectious eosinophilic diseases. Here, we aim to investigate whether eosinophils generate functional EETs as a direct response to TSLP, and further to study the extra- and intracellular mechanisms involved in this process as well as TSLP receptor (TSLPR) expression by eosinophils in vitro and in vivo.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Pharmacology 04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Morshed, Md. Mahbubul, Yousefi, Shida, Simon, Hans-Uwe, Simon, Dagmar |
ISSN: |
0105-4538 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:35 |
Last Modified: |
02 Mar 2023 23:21 |
Publisher DOI: |
10.1111/j.1398-9995.2012.02868.x |
PubMed ID: |
22764833 |
Web of Science ID: |
000307380000006 |
URI: |
https://boris.unibe.ch/id/eprint/14106 (FactScience: 220915) |
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