Yousefi, Shida

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2024

Gigon, Lea; Müller, Philipp; Haenni, Beat; Iacovache, Ioan; Barbo, Maruša; Gosheva, Gordana; Yousefi, Shida; Soragni, Alice; von Ballmoos, Christoph; Zuber, Benoît; Simon, Hans-Uwe (2024). Membrane damage by MBP-1 is mediated by pore formation and amplified by mtDNA. Cell reports, 43(4), p. 114084. Cell Press 10.1016/j.celrep.2024.114084

Greuter, Thomas; Straumann, Alex; Fernández Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Chanwangpong, Apinya; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M and Simon, Hans-Uwe (2024). A Multicenter Long-Term Cohort Study of Eosinophilic Esophagitis Variants and Their Progression to EOE over Time. Clinical and translational gastroenterology, 15(4), e00664. Wolters Kluwer Health 10.14309/ctg.0000000000000664

Chen, Yihe; Markov, Nikita; Gigon, Lea; Hosseini, Aref; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2024). The BK Channel Limits the Pro-Inflammatory Activity of Macrophages. Cells, 13(4) MDPI 10.3390/cells13040322

Stojkov, Darko; Yousefi, Shida; Simon, Hans-Uwe (2024). NETs: Important players in asthma? Journal of allergy and clinical immunology, 153(1), pp. 100-102. Elsevier 10.1016/j.jaci.2023.09.031

Bürgler, Christina; Dutoit, Danielle; Radonjic-Hoesli, Susanne; Thormann, Kathrin; Lehmann, Mathias; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2024). Dupilumab normalizes correlates of lysosomal function in atopic dermatitis. JEADV Clinical Practice, 3(2), pp. 478-486. Wiley 10.1002/jvc2.307

2023

Gigon, Lea; Fettrelet, Timothée; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2023). Eosinophils from A to Z. Allergy, 78(7), pp. 1810-1846. Wiley 10.1111/all.15751

Peng, Shuang; Gao, Jian; Stojkov, Darko; Yousefi, Shida; Simon, Hans-Uwe (2023). Established and emerging roles for mitochondria in neutrophils. Immunological reviews, 314(1), pp. 413-426. Wiley-Blackwell 10.1111/imr.13158

Hosseini, Aref; Stojkov, Darko; Fettrelet, Timothée; Bilyy, Rostyslav; Yousefi, Shida; Simon, Hans-Uwe (2023). Transcriptional Insights of Oxidative Stress and Extracellular Traps in Lung Tissues of Fatal COVID-19 Cases. International journal of molecular sciences, 24(3) MDPI 10.3390/ijms24032646

Stojkov, Darko; Claus, Meike J; Kozlowski, Evelyne; Oberson, Kevin; Schaeren, Olivier P; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2023). NET formation is independent of gasdermin D and pyroptotic cell death. Science signaling, 16(769), eabm0517. American Association for the Advancement of Science 10.1126/scisignal.abm0517

Gigon, Lea; Fettrelet, Timothée; Miholic, Marta; McLeish, Kenneth R; Yousefi, Shida; Stojkov, Darko; Simon, Hans-Uwe (2023). Syntaxin-4 and SNAP23 are involved in neutrophil degranulation, but not in the release of mitochondrial DNA during NET formation. Frontiers in immunology, 14(1272699), p. 1272699. Frontiers Research Foundation 10.3389/fimmu.2023.1272699

Hosseini, Aref; Germic, Nina; Markov, Nikita; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2023). The regulatory role of eosinophils in adipose tissue depends on autophagy. Frontiers in immunology, 14, p. 1331151. Frontiers Research Foundation 10.3389/fimmu.2023.1331151

2022

Peng, Shuang; Stojkov, Darko; Gao, Jian; Oberson, Kevin; Latzin, Philipp; Casaulta, Carmen; Yousefi, Shida; Simon, Hans-Uwe (2022). Nascent RHOH acts as a molecular brake on actomyosin-mediated effector functions of inflammatory neutrophils. PLoS biology, 20(9), e3001794. Public Library of Science 10.1371/journal.pbio.3001794

Greuter, Thomas; Straumann, Alex; Fernandez-Marrero, Yuniel; Germic, Nina; Hosseini, Aref; Yousefi, Shida; Simon, Dagmar; Collins, Margaret H; Bussmann, Christian; Chehade, Mirna; Dellon, Evan S; Furuta, Glenn T; Gonsalves, Nirmala; Hirano, Ikuo; Moawad, Fouad J; Biedermann, Luc; Safroneeva, Ekaterina; Schoepfer, Alain M; Simon, Hans-Uwe (2022). Characterization of eosinophilic esophagitis variants by clinical, histological and molecular analyses: A cross-sectional multi-center study. Allergy, 77(8), pp. 2520-2533. Wiley 10.1111/all.15233

Fallegger, Angela; Priola, Martina; Artola-Borán, Mariela; Núñez, Nicolás Gonzalo; Wild, Sebastian; Gurtner, Alessandra; Becher, Burkhard; Yousefi, Shida; Simon, Hans-Uwe; Arnold, Isabelle C; Müller, Anne (2022). TGF-β production by eosinophils drives the expansion of peripherally induced neuropilin- RORγt+ regulatory T-cells during bacterial and allergen challenge. Mucosal immunology, 15(3), pp. 504-514. Springer Nature 10.1038/s41385-022-00484-0

Klapan, Kim; Simon, Dagmar; Karaulov, Alexander; Gomzikova, Marina; Rizvanov, Albert; Yousefi, Shida; Simon, Hans-Uwe (2022). Autophagy and Skin Diseases. Frontiers in Pharmacology, 13, p. 844756. Frontiers 10.3389/fphar.2022.844756

Artola-Borán, Mariela; Fallegger, Angela; Priola, Martina; Jeske, Rima; Waterboer, Tim; Dohlman, Anders B; Shen, Xiling; Wild, Sebastian; He, Jiazhuo; Levesque, Mitchell P; Yousefi, Shida; Simon, Hans-Uwe; Cheng, Phil F; Müller, Anne (2022). Mycobacterial infection aggravates Helicobacter pylori-induced gastric preneoplastic pathology by redirection of de novo induced Treg cells. Cell reports, 38(6), p. 110359. Cell Press 10.1016/j.celrep.2022.110359

Stojkov, Darko; Gigon, Lea; Peng, Shuang; Lukowski, Robert; Ruth, Peter; Karaulov, Alexander; Rizvanov, Albert; Barlev, Nickolai A; Yousefi, Shida; Simon, Hans-Uwe (2022). Physiological and Pathophysiological Roles of Metabolic Pathways for NET Formation and Other Neutrophil Functions. Frontiers in immunology, 13, p. 826515. Frontiers Research Foundation 10.3389/fimmu.2022.826515

2021

Klapan, Kim; Frangež, Živa; Markov, Nikita; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2021). Evidence for lysosomal dysfunction within the epidermis in psoriasis and atopic dermatitis. Journal of investigative dermatology, 141(12), 2838-2848.e4. Elsevier 10.1016/j.jid.2021.05.016

Ackermann, Maximilian; Anders, Hans-Joachim; Bilyy, Rostyslav; Bowlin, Gary L; Daniel, Christoph; De Lorenzo, Rebecca; Egeblad, Mikala; Henneck, Timo; Hidalgo, Andrés; Hoffmann, Markus; Hohberger, Bettina; Kanthi, Yogendra; Kaplan, Mariana J; Knight, Jason S; Knopf, Jasmin; Kolaczkowska, Elzbieta; Kubes, Paul; Leppkes, Moritz; Mahajan, Aparna; Manfredi, Angelo A; ... (2021). Patients with COVID-19: in the dark-NETs of neutrophils. Cell death and differentiation, 28(11), pp. 3125-3139. Springer Nature 10.1038/s41418-021-00805-z

Fettrelet, Timothée; Gigon, Lea; Karaulov, Alexander; Yousefi, Shida; Simon, Hans-Uwe (2021). The Enigma of Eosinophil Degranulation. International journal of molecular sciences, 22(13) MDPI 10.3390/ijms22137091

Germic, Nina; Hosseini, Aref; Stojkov, Darko; Oberson, Kevin; Claus, Meike; Benarafa, Charaf; Calzavarini, Sara; Angelillo-Scherrer, Anne; Arnold, Isabelle C; Müller, Anne; Riether, Carsten; Yousefi, Shida; Simon, Hans-Uwe (2021). ATG5 promotes eosinopoiesis, but inhibits eosinophil effector functions. Blood, 137(21), pp. 2958-2969. American Society of Hematology 10.1182/blood.2020010208

Germic, Nina; Hosseini, Aref; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Regulation of eosinophil functions by autophagy. Seminars in immunopathology, 43(3), pp. 347-362. Springer 10.1007/s00281-021-00860-1

Rohner, Maria Helena; Thormann, Kathrin; Cazzaniga, Simone; Yousefi, Shida; Simon, Hans-Uwe; Schlapbach, Christoph; Simon, Dagmar (2021). Dupilumab reduces inflammation and restores the skin barrier in patients with atopic dermatitis. Allergy, 76(4), pp. 1268-1270. Wiley-Blackwell 10.1111/all.14664

Germic, Nina; Fettrelet, Timothée; Stojkov, Darko; Hosseini, Aref; Horn, Michael P.; Karaulov, Alexander; Simon, Dagmar; Yousefi, Shida; Simon, Hans-Uwe (2021). The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation. Cells, 10(2) MDPI 10.3390/cells10020306

Gigon, Lea; Yousefi, Shida; Karaulov, Alexander; Simon, Hans-Uwe (2021). Mechanisms of toxicity mediated by neutrophil and eosinophil granule proteins. Allergology international, 70(1), pp. 30-38. Elsevier 10.1016/j.alit.2020.11.003

Wang, Xiaoliang; Avsec, Damjan; Obreza, Aleš; Yousefi, Shida; Mlinarič-Raščan, Irena; Simon, Hans-Uwe (2021). A Putative Serine Protease is Required to Initiate the RIPK3-MLKL-Mediated Necroptotic Death Pathway in Neutrophils. Frontiers in Pharmacology, 11, p. 614928. Frontiers 10.3389/fphar.2020.614928

Frangez, Ziva; Gérard, Deborah; He, Zhaoyue; Gavriil, Marios; Fernández-Marrero, Yuniel; Jafari, S. Morteza Seyed; Hunger, Robert E.; Lucarelli, Philippe; Yousefi, Shida; Sauter, Thomas; Sinkkonen, Lasse; Simon, Hans-Uwe (2021). ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1. Frontiers in oncology, 11, p. 721624. Frontiers Research Foundation 10.3389/fonc.2021.721624

2020

Arnold, Isabelle C; Artola-Boran, Mariela; Gurtner, Alessandra; Bertram, Katrin; Bauer, Michael; Frangez, Ziva; Becher, Burkhard; Kopf, Manfred; Yousefi, Shida; Simon, Hans-Uwe; Tzankov, Alexandar; Müller, Anne (2020). The GM-CSF-IRF5 signaling axis in eosinophils promotes antitumor immunity through activation of type 1 T cell responses. Journal of experimental medicine, 217(12) Rockefeller University Press 10.1084/jem.20190706

Wang, Xiaoliang; Gessier, Francois; Perozzo, Remo; Stojkov, Darko; Hosseini, Aref; Amirshahrokhi, Keyvan; Kuchen, Stefan; Yousefi, Shida; Lötscher, Pius; Simon, Hans-Uwe (2020). RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α. Journal of immunology, 205(6), pp. 1653-1663. American Association of Immunologists 10.4049/jimmunol.2000113

Karlen, Hélène; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2020). IL-15 Expression Pattern in Atopic Dermatitis. International archives of allergy and immunology, 181(6), pp. 417-421. Karger 10.1159/000508515

Yousefi, Shida; Simon, Dagmar; Stojkov, Darko; Karsonova, Antonina; Karaulov, Alexander; Simon, Hans-Uwe (2020). In vivo evidence for extracellular DNA trap formation. Cell death & disease, 11(4), p. 300. Nature Publishing Group 10.1038/s41419-020-2497-x

Simon, Dagmar; Yousefi, Shida; Cazzaniga, Simone; Bürgler, Christina; Radonjic, Susanne; Houriet, Carine; Heidemeyer, Kristine; Klötgen, Hans-Willhelm; Kozlowski, Evelyne; Borradori, Luca; Simon, Hans-Uwe (2020). Mepolizumab failed to affect bullous pemphigoid: a randomized, placebo-controlled, double-blind phase 2 pilot study. Allergy, 75(3), pp. 669-672. Wiley 10.1111/all.13950

Surmiak, Marcin; Gielicz, Anna; Stojkov, Darko; Szatanek, Rafał; Wawrzycka-Adamczyk, Katarzyna; Yousefi, Shida; Simon, Hans-Uwe; Sanak, Marek (2020). LTB4 and 5-oxo-ETE from extracellular vesicles stimulate neutrophils in granulomatosis with polyangiitis. Journal of lipid research, 61(1), pp. 1-9. American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.M092072

Simon, Hans-Uwe; Yousefi, Shida; Germic, Nina; Arnold, Isabelle C.; Haczku, Angela; Karaulov, Alexander V.; Simon, Dagmar; Rosenberg, Helene F. (2020). The Cellular Functions of Eosinophils: Collegium Internationale Allergologicum (CIA) Update 2020. International archives of allergy and immunology, 181(1), pp. 11-23. Karger 10.1159/000504847

2019

Yadav, Sandeep Kumar; Stojkov, Darko; Feigelson, Sara W; Roncato, Francesco; Simon, Hans-Uwe; Yousefi, Shida; Alon, Ronen (2019). Chemokine-triggered microtubule polymerization promotes neutrophil chemotaxis and invasion but not transendothelial migration. Journal of leukocyte biology, 105(4), pp. 755-766. Society for Leukocyte Biology 10.1002/JLB.3A1118-437RR

Boeltz, Sebastian; Amini, Poorya; Anders, Hans-Joachim; Andrade, Felipe; Bilyy, Rostyslav; Chatfield, Simon; Cichon, Iwona; Clancy, Danielle M; Desai, Jyaysi; Dumych, Tetiana; Dwivedi, Nishant; Gordon, Rachael Ann; Hahn, Jonas; Hidalgo, Andrés; Hoffmann, Markus H; Kaplan, Mariana J; Knight, Jason S; Kolaczkowska, Elzbieta; Kubes, Paul; Leppkes, Moritz; ... (2019). To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. Cell death and differentiation, 26(3), pp. 395-408. Nature Publishing Group 10.1038/s41418-018-0261-x

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: monocytes, macrophages, dendritic cells and antigen presentation. Cell death and differentiation, 26(4), pp. 715-727. Nature Publishing Group 10.1038/s41418-019-0297-6

Germic, Nina; Frangez, Ziva; Yousefi, Shida; Simon, Hans-Uwe (2019). Regulation of the innate immune system by autophagy: neutrophils, eosinophils, mast cells, NK cells. Cell death and differentiation, 26(4), pp. 703-714. Nature Publishing Group 10.1038/s41418-019-0295-8

Yousefi, Shida; Stojkov, Darko; Germic, Nina; Simon, Dagmar; Wang, Xiaoliang; Benarafa, Charaf; Simon, Hans-Uwe (2019). Untangling "NETosis" from NETs. European journal of immunology, 49(2), pp. 221-227. Wiley-VCH 10.1002/eji.201747053

2018

Arnold, Isabelle C; Artola-Borán, Mariela; Tallón de Lara, Paulino; Kyburz, Andreas; Taube, Christian; Ottemann, Karen; van den Broek, Maries; Yousefi, Shida; Simon, Hans-Uwe; Müller, Anne (2018). Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. Journal of experimental medicine, 215(8), pp. 2055-2072. Rockefeller University Press 10.1084/jem.20172049

Amini, Poorya; Stojkov, Darko; Felser, Andrea; Jackson, Christopher B; Courage, Carolina; Schaller, André; Gelman, Laurent; Soriano, Maria Eugenia; Nuoffer, Jean-Marc; Scorrano, Luca; Benarafa, Charaf; Yousefi, Shida; Simon, Hans-Uwe (2018). Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production. Nature communications, 9(1), p. 2958. Nature Publishing Group 10.1038/s41467-018-05387-y

Yousefi, Shida; Sharma, Satish K; Stojkov, Darko; Germic, Nina; Aeschlimann, Salome; Ge, Moyar Q; Flayer, Cameron H; Larson, Erik D; Redai, Imre G; Zhang, Suhong; Koziol-White, Cynthia J; Karikó, Katalin; Simon, Hans-Uwe; Haczku, Angela (2018). Oxidative damage of SP-D abolishes control of eosinophil extracellular DNA trap formation. Journal of leukocyte biology, 104(1), pp. 205-214. Society for Leukocyte Biology 10.1002/JLB.3AB1117-455R

de Graauw, E; Sitaru, C; Horn, Michael; Borradori, Luca; Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2018). Monocytes enhance neutrophil-induced blister formation in an ex vivo model of bullous pemphigoid. Allergy, 73(5), pp. 1119-1130. Wiley-Blackwell 10.1111/all.13376

Gevaert, Elien; Yousefi, Shida; Bachert, Claus; Simon, Hans-Uwe (2018). Reply. The Journal of allergy and clinical immunology, 141(3), pp. 1164-1165. Elsevier 10.1016/j.jaci.2017.05.048

Wang, Xiaoliang; Yousefi, Shida; Simon, Hans-Uwe (2018). Necroptosis and neutrophil-associated disorders. Cell death & disease, 9(2), p. 111. Nature Publishing Group 10.1038/s41419-017-0058-8

Jin, Jing; Britschgi, Adrian; Schläfli, Anna M.; Humbert, Magali; Shan-Krauer, Deborah; Batliner, Jasmin; Federzoni, Elena A.; Ernst, Marion; Torbett, Bruce E.; Yousefi, Shida; Simon, Hans-Uwe; Tschan, Mario (2018). Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxidative medicine and cellular longevity, 2018, p. 1482795. Hindawi 10.1155/2018/1482795

Simon, Dagmar; Radonjic-Hösli, S.; Straumann, A.; Yousefi, Shida; Simon, Hans-Uwe (2018). Epithelial barrier defects and eosinophil extracellular trap formation in active eosinophilic esophagitis. In: 31st Symposium of the Collegium Internationale Allergologicum (pp. 45-47). Pacini Editore S.r.l.

2017

Stojkov, Darko; Amini, Poorya; Oberson, Kevin; Sokollik, Christiane; Duppenthaler, Andrea; Simon, Hans-Uwe; Yousefi, Shida (2017). ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. Journal of cell biology, 216(12), pp. 4073-4090. Rockefeller University Press 10.1083/jcb.201611168

Radonjic-Hoesli, Susanne; Wang, Xiaoliang; de Graauw, Elisabeth Louisa Maria; Stoeckle, Christina; Styp-Rekowska, Beata; Hlushchuk, Ruslan; Simon, Dagmar; Späth, Peter Julius; Yousefi, Shida; Simon, Hans-Uwe (2017). Adhesion-induced eosinophil cytolysis requires the receptor-interacting protein kinase 3 (RIPK3)-mixed lineage kinase-like (MLKL) signaling pathway, which is counterregulated by autophagy. The Journal of allergy and clinical immunology, 140(6), pp. 1632-1642. Elsevier 10.1016/j.jaci.2017.01.044

Germic, Nina; Stojkov, Darko; Oberson, Kevin; Yousefi, Shida; Simon, Hans-Uwe (2017). Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation. Immunology, 152(3), pp. 517-525. Wiley-Blackwell 10.1111/imm.12790

de Graauw, Elisabeth Louisa Maria; Sitaru, Cassian; Horn, Michael Peter; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2017). Evidence for a role of eosinophils in blister formation in bullous pemphigoid. Allergy, 72(7), pp. 1105-1113. Wiley-Blackwell 10.1111/all.13131

Vicari, Alain P; Schoepfer, Alain M; Meresse, Bertrand; Goffin, Laurence; Léger, Olivier; Josserand, Soheila; Guégan, Nicolas; Yousefi, Shida; Straumann, Alex; Cerf-Bensussan, Nadine; Simon, Hans-Uwe; Chvatchko, Yolande (2017). Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis. mAbs, 9(6), pp. 927-944. Taylor & Francis 10.1080/19420862.2017.1332553

Gevaert, Elien; Zhang, Nan; Krysko, Olga; Lan, Feng; Holtappels, Gabriële; De Ruyck, Natalie; Nauwynck, Hans; Yousefi, Shida; Simon, Hans-Uwe; Bachert, Claus (2017). Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in severe airway inflammation. The Journal of allergy and clinical immunology, 139(6), 1849-1860.e6. Elsevier 10.1016/j.jaci.2017.01.019

2016

Stoeckle, Christina; Geering, Barbara; Yousefi, Shida; Rožman, Saša; Andina, Nicola; Benarafa, Charaf; Simon, Hans-Uwe (2016). RhoH is a negative regulator of eosinophilopoiesis. Cell death and differentiation, 23(12), pp. 1961-1972. Nature Publishing Group 10.1038/cdd.2016.73

Wang, Xiaoliang; Simon, Hans-Uwe; He, Zhaoyue; Liu, He; Yousefi, Shida (2016). Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming. Journal of immunology, 197(10), pp. 4090-4100. American Association of Immunologists 10.4049/jimmunol.1600051

Amini, Poorya; Stojkov, Darko; Wang, Xiaoliang; Wicki, Simone; Kaufmann, Thomas; Wong, Wendy Wei-Lynn; Simon, Hans-Uwe; Yousefi, Shida (2016). NET formation can occur independently of RIPK3 and MLKL signaling. European journal of immunology, 46(1), pp. 178-184. Wiley-VCH 10.1002/eji.201545615

Simon, Hans-Uwe; Yousefi, Shida; Simon, Dagmar (2016). Basophils can form extracellular DNA traps independent of a functional NADPH oxidase. In: Maurer, Markus; Behrendt, Heidrum (eds.) Allergies: Current challenges and solutions. Proceedings of the 30th Symposium of the Collegium Internationale Allergologicum (CIA) (pp. 67-70). Ospedaletto (Pisa): Pacini editore Medicina

Yousefi, Shida; Simon, Hans-Uwe (2016). NETosis - Does It Really Represent Nature's "Suicide Bomber"? Frontiers in immunology, 7(328), p. 328. Frontiers Research Foundation 10.3389/fimmu.2016.00328

Stojkov, Darko (2016). Actin polymerization and its glutathionylation are required for NET formation (Submitted). (Dissertation, Institute of Pharmacology, Faculty of Medicine of the University of Bern)

2015

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Hurrell, Benjamin P; Schuster, Steffen; Grün, Eva; Coutaz, Manuel; Williams, Roderick A; Held, Werner; Malissen, Bernard; Malissen, Marie; Yousefi, Shida; Simon, Hans-Uwe; Müller, Andreas J; Tacchini-Cottier, Fabienne (2015). Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion. PLoS pathogens, 11(5), e1004929. Public Library of Science 10.1371/journal.ppat.1004929

Simon, Dagmar; Radonjic, Susanne Irene; Straumann, A; Yousefi, Shida; Simon, Hans-Uwe (2015). Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation. Allergy, 70(4), pp. 443-452. Wiley-Blackwell 10.1111/all.12570

Soragni, Alice; Yousefi, Shida; Stoeckle, Christina; Soriaga, Angela B; Sawaya, Michael R; Kozlowski, Eveline; Schmid, Ines; Radonjic-Hoesli, Susanne; Boutet, Sebastien; Williams, Garth J; Messerschmidt, Marc; Seibert, M Marvin; Cascio, Duilio; Zatsepin, Nadia A; Burghammer, Manfred; Riekel, Christian; Colletier, Jacques-Philippe; Riek, Roland; Eisenberg, David S and Simon, Hans-Uwe (2015). Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation. Molecular cell, 57(6), pp. 1011-1021. Cell Press 10.1016/j.molcel.2015.01.026

Rozman, Sasa; Yousefi, Shida; Oberson, Kevin; Kaufmann, Thomas; Benarafa, Charaf; Simon, Hans-Uwe (2015). The generation of neutrophils in the bone marrow is controlled by autophagy. Cell death and differentiation, 22(3), pp. 445-456. Nature Publishing Group 10.1038/cdd.2014.169

2014

de Graauw, Elisabeth Louisa; Sitaru, C.; Borradori, Luca; Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (September 2014). The pathogenic role of neutrophils, eosinophils and peripheral blood mononuclear cells (PBMC's) in bullous pemphigoid. Dermatologica Helvetica, 26(6). Karger

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Simon, Hans-Uwe; Yousefi, Shida; Schmid, Ines; Friis, Robert (2014). ATG5 can regulate p53 expression and activation. Cell death & disease, 5(e1339), pp. 176-177. Nature Publishing Group 10.1038/cddis.2014.308

Yousefi, Shida; Simon, Hans-Uwe; Simon, Dagmar (2014). Eosinophil extracellular traps: potential role(s) in eosinophilic diseases. In: Galli, Stephen J.; You-Young, Kim (eds.) Allergic Diseases: from Mechanisms to Cures. Proceedings of the 29th Symposium of the Collegium Internationale Allergologicum. Allergologia e immunologia (pp. 87-89). Pisa: Pacini Editore S.p.A.

Simon, Dagmar; Simon, Hans-Uwe; Yousefi, Shida (2014). Eosinophil extracellular trap formation in response to thymic stromal lymphopoietin stimulation. In: Galli, Stephen J.; You-Young, Kim (eds.) Allergic Diseases: from mechanisms to cures. Proceedings of the 29th Symposium of the Collegium Internationale Allergologicum. Allergologia e immunologia (pp. 83-86). Pisa: Pacini Editore

2013

Simon, Dagmar; Simon, Hans-Uwe; Yousefi, Shida (2013). Extracellular DNA traps in allergic, infectzious, and autoimmune diseases. Allergy, 68(4), pp. 409-416. Wiley-Blackwell 10.1111/all.12111

He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104

Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130

Liu, He; He, Zhaoyue; von Rütte, Thomas; Yousefi, Shida; Hunger, Robert E.; Simon, Hans-Uwe (2013). Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma. Science translational medicine, 5(202), 202ra123. American Association for the Advancement of Science 10.1126/scitranslmed.3005864

2012

Salemi, Souzan; Yousefi, Shida; Constantinescu, Mihai A; Fey, Martin F; Simon, Hans-Uwe (2012). Autophagy is required for self-renewal and differentiation of adult human stem cells. Cell research, 22(2), pp. 432-5. London: Nature Publishing Group 10.1038/cr.2011.200

Yousefi, Shida; Simon, Dagmar; Simon, Hans-Uwe (2012). Eosinophil extracellular DNA traps: molecular mechanisms and potential roles in disease. Current opinion in immunology, 24(6), pp. 736-9. Kidlington, UK: Elsevier 10.1016/j.coi.2012.08.010

Morshed, M; Yousefi, S; Stöckle, C; Simon, H-U; Simon, D (2012). Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps. Allergy, 67(9), pp. 1127-37. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2012.02868.x

Kerstan, A; Simon, H-U; Yousefi, S; Leverkus, M (2012). Extensive accumulation of eosinophil extracellular traps in bullous delayed-pressure urticaria: a pathophysiological link? British journal of dermatology, 166(5), pp. 1151-2. Oxford: Wiley-Blackwell 10.1111/j.1365-2133.2012.10848.x

Simon, HU; Yousefi, S (2012). Mitochondrial DNA released by eosinophils contributes to innate immunity. Pisa: Pacini Editore S.p.A.

2011

Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007

Mihalache, Cristina C; Yousefi, Shida; Conus, Sébastien; Villiger, Peter M; Schneider, E Marion; Simon, Hans-Uwe (2011). Inflammation-associated autophagy-related programmed necrotic death of human neutrophils characterized by organelle fusion events. Journal of immunology, 186(11), pp. 6532-42. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.1004055

Dworski, Ryszard; Simon, Hans-Uwe; Hoskins, Aimee; Yousefi, Shida (2011). Eosinophil and neutrophil extracellular DNA traps in human allergic asthmatic airways. Journal of allergy and clinical immunology, 127(5), pp. 1260-6. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.12.1103

Simon, Dagmar; Hoesli, Susanne; Roth, Nina; Staedler, Simon; Yousefi, Shida; Simon, Hans-Uwe (2011). Eosinophil extracellular DNA traps in skin diseases. Journal of allergy and clinical immunology, 127(1), pp. 194-9. St. Louis, Mo.: Mosby 10.1016/j.jaci.2010.11.002

2010

El-Hashim, Ahmed; Yousefi, Shida; Edafiogho, Ivan; Raghupathy, Raj; Yousif, Mariam; Simon, Hans-Uwe (2010). Anti-inflammatory and immunosuppressive effects of the enaminone E121. European journal of pharmacology, 632(1-3), pp. 73-78. Amsterdam: Elsevier 10.1016/j.ejphar.2009.12.004

Schmidt-Mende, Jan; Geering, Barbara; Yousefi, Shida; Simon, Hans-Uwe (2010). Lysosomal degradation of RhoH protein upon antigen receptor activation in T but not B cells. European journal of immunology, 40(2), pp. 525-9. Weinheim: Wiley-VCH 10.1002/eji.200939556

2009

Salemi, S; Yousefi, S; Simon, D; Schmid, I; Moretti, L; Scapozza, L; Simon, H-U (2009). A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome. Allergy, 64(6), pp. 913-8. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2009.01943.x

Yousefi, S; Mihalache, C; Kozlowski, E; Schmid, I; Simon, H U (2009). Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps. Cell death and differentiation, 16(11), pp. 1438-44. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.96

Daryadel, Arezoo; Yousefi, Shida; Troi, David; Schmid, Inès; Schmidt-Mende, Jan; Mordasini, Carlo; Dahinden, Clemens A; Ziemiecki, Andrew; Simon, Hans-Uwe (2009). RhoH/TTF negatively regulates leukotriene production in neutrophils. Journal of immunology, 182(10), pp. 6527-32. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803846

Yousefi, Shida; Simon, Hans-Uwe (2009). Autophagy in cells of the blood. Biochimica and biophysica acta - molecular and cell biology of lipids, 1793(9), pp. 1461-4. New York, N.Y.: Elsevier 10.1016/j.bbamcr.2008.12.023

Yousefi, Shida; Simon, Hans-Uwe (2009). Autophagy in cancer and chemotherapy. Results and problems in cell differentiation, 49, pp. 183-190. Berlin: Springer

2008

Simon, Dagmar; Salemi, Souzan; Yousefi, Shida; Simon, Hans-Uwe (2008). Primary resistance to imatinib in Fip1-like 1-platelet-derived growth factor receptor alpha-positive eosinophilic leukemia. Journal of allergy and clinical immunology, 121(4), pp. 1054-6. St. Louis, Mo.: Mosby 10.1016/j.jaci.2007.11.027

Federzoni, Elena; Gordon, Grace; Müller, Stefan; Schmid, Inès; Simon, Hans-Uwe; Yousefi, Shida (2008). Expression of CD95 on mature leukocytes of MRL/lpr mice after transplantation of genetically modified bone marrow stem cells. Immunology letters, 117(1), pp. 45-9. Amsterdam: Elsevier 10.1016/j.imlet.2007.11.019

Kuhn, A; Leupin, N; Fey, M.F.; Yousefi, S; Simon, H.U. (2008). Leukaemia cell lines are robust in vitro models - response to MacLeod & Drexler. British journal of haematology(142), pp. 138-141. Oxford: Wiley-Blackwell

Yousefi, Shida; Gold, Jeffrey A; Andina, Nicola; Lee, James J; Kelly, Ann M; Kozlowski, Evelyne; Schmid, Inès; Straumann, Alex; Reichenbach, Janine; Gleich, Gerald J; Simon, Hans-Uwe (2008). Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense. Nature medicine, 14(9), pp. 949-53. New York, N.Y.: Nature Publishing Group 10.1038/nm.1855

2007

Salemi, Souzan; Yousefi, Shida; Lochmatter, Didier; Eblé, Andrée; Deladoëy, Johnny; Robinson, Iain C A F; Simon, Hans-Uwe; Mullis, Primus E (2007). Isolated autosomal dominant growth hormone deficiency: stimulating mutant GH-1 gene expression drives GH-1 splice-site selection, cell proliferation, and apoptosis. Endocrinology, 148(1), pp. 45-53. Chevy Chase, Md.: Endocrine Society 10.1210/en.2006-0772

Yousefi, Shida; Simon, Hans-Uwe (2007). Apoptosis regulation by autophagy gene 5. Critical reviews in oncology, hematology, 63(3), pp. 241-4. Boca Raton, Fla.: Elsevier 10.1016/j.critirevonc.2007.06.005

Tsilimparis, N; Alevizakos, P; Yousefi, S; Hanack, U; Im Spring, B; Blank, B; Rückert, R I (2007). [Endovascular therapy of an abdominal aortic aneurysm in a renal transplant recipient]. Zentralblatt für Chirurgie, 132(3), 220-5; discussion 225-6. Stuttgart: Thieme 10.1055/s-2007-981162

White, Amy M; Banovac, Filip; Yousefi, Shadi; Slack, Rebecca S; Spies, James B (2007). Uterine fibroid embolization: the utility of aortography in detecting ovarian artery collateral supply. Radiology, 244(1), pp. 291-8. Oak Brook, Ill.: Radiological Society of North America RSNA 10.1148/radiol.2441060796

Tsilimparis, Nikolaos; Hanack, Ulrich; Yousefi, Sharom; Alevizakos, Pavlos; Rückert, Ralph I (2007). Cystic adventitial disease of the popliteal artery: an argument for the developmental theory. Journal of vascular surgery, 45(6), pp. 1249-52. Amsterdam: Elsevier 10.1016/j.jvs.2007.01.051

Yousefi, S; Simon, HU (2007). Taxol Therapy revisited. Blood, 110(2007), p. 3492. Washington, D.C.: American Society of Hematology 10.1182/blood-2007-08-105486

2006

Yousefi, Shida; Perozzo, Remo; Schmid, Inès; Ziemiecki, Andrew; Schaffner, Thomas; Scapozza, Leonardo; Brunner, Thomas; Simon, Hans-Uwe (2006). Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nature cell biology, 8(10), pp. 1124-32. London: Nature Publishing Group 10.1038/ncb1482

Daryadel, Arezoo; Grifone, Remo Filippo; Simon, Hans-Uwe; Yousefi, Shida (2006). Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alpha. Journal of biological chemistry, 281(37), pp. 27653-61. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M604051200

Vassina, Ekatherina M; Yousefi, Shida; Simon, Dagmar; Zwicky, Caroline; Conus, Sébastien; Simon, Hans-Uwe (2006). cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis. European journal of immunology, 36(7), pp. 1975-84. Weinheim: Wiley-VCH 10.1002/eji.200635943

Martinelli, S; Kostylina, G; Niggli, V; Baumann, C; Fey, M F; Wendel, H-G; Lowe, S W; Yousefi, S; Simon, H-U (2006). Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils. Oncogene, 25(52), pp. 6915-23. Basingstoke, UK: Nature Publishing Group 10.1038/sj.onc.1209692

Salemi, Souzan; Yousefi, Shida; Eblé, Andrée; Deladoëy, Johnny; Mullis, Primus E (2006). Impact of del32-71-GH (exon 3 skipped GH) on intracellular GH distribution, secretion and cell viability: a quantitative confocal microscopy analysis. Hormone research, 65(3), pp. 132-41. Basel: Karger 10.1159/000091607

Nachbur, Ueli; Kassahn, Daniela; Yousefi, Shida; Legler, Daniel F; Brunner, Thomas (2006). Posttranscriptional regulation of Fas (CD95) ligand killing activity by lipid rafts. Blood, 107(7), pp. 2790-6. Washington, D.C.: American Society of Hematology 10.1182/blood-2005-07-2744

2004

Baumann, Ralf; Yousefi, Shida; Simon, Dagmar; Russmann, Stefan; Mueller, Christoph; Simon, Hans-Uwe (2004). Functional expression of CD134 by neutrophils. European journal of immunology, 34(8), pp. 2268-2275. Wiley-VCH 10.1002/eji.200424863

Altznauer, Frank; Martinelli, Sibylla; Yousefi, Shida; Thürig, Christine; Schmid, Inès; Conway, Edward M; Schöni, Martin H; Vogt, Peter; Mueller, Christoph; Fey, Martin F; Zangemeister-Wittke, Uwe; Simon, Hans-Uwe (2004). Inflammation-associated cell cycle-independent block of apoptosis by survivin in terminally differentiated neutrophils. The Journal of experimental medicine, 199(10), pp. 1343-1354. Rockefeller Univ. Press 10.1084/jem.20032033

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