Exercise benefits in cardiovascular diseases: from mechanisms to clinical implementation.

Valenzuela, Pedro L; Ruilope, Luis M; Santos-Lozano, Alejandro; Wilhelm, Matthias; Kränkel, Nicolle; Fiuza-Luces, Carmen; Lucia, Alejandro (2023). Exercise benefits in cardiovascular diseases: from mechanisms to clinical implementation. European Heart Journal, 44(21), pp. 1874-1889. Oxford University Press 10.1093/eurheartj/ehad170

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There is a pandemic of physical inactivity that appears to parallel the widespread prevalence of cardiovascular disease (CVD). Yet, regular physical activity (PA) and exercise can play an important role not only in primary cardiovascular prevention but also in secondary prevention. This review discusses some of the main cardiovascular effects of PA/exercise and the mechanisms involved, including a healthier metabolic milieu with attenuation of systemic chronic inflammation, as well as adaptations at the vascular (antiatherogenic effects) and heart tissue (myocardial regeneration and cardioprotection) levels. The current evidence for safe implementation of PA and exercise in patients with CVD is also summarized.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Pharmacology

UniBE Contributor:

Wilhelm, Matthias

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0195-668X

Publisher:

Oxford University Press

Language:

English

Submitter:

Pubmed Import

Date Deposited:

03 Apr 2023 12:26

Last Modified:

25 Mar 2024 09:55

Publisher DOI:

10.1093/eurheartj/ehad170

PubMed ID:

37005351

Uncontrolled Keywords:

Cardiovascular mortality Exercise and cardiovascular disease Exercise implementation Primary cardiovascular prevention Secondary cardiovascular prevention

BORIS DOI:

10.48350/181395

URI:

https://boris.unibe.ch/id/eprint/181395

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