Valenzuela, Pedro L; Ruilope, Luis M; Santos-Lozano, Alejandro; Wilhelm, Matthias; Kränkel, Nicolle; Fiuza-Luces, Carmen; Lucia, Alejandro (2023). Exercise benefits in cardiovascular diseases: from mechanisms to clinical implementation. European Heart Journal, 44(21), pp. 1874-1889. Oxford University Press 10.1093/eurheartj/ehad170
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There is a pandemic of physical inactivity that appears to parallel the widespread prevalence of cardiovascular disease (CVD). Yet, regular physical activity (PA) and exercise can play an important role not only in primary cardiovascular prevention but also in secondary prevention. This review discusses some of the main cardiovascular effects of PA/exercise and the mechanisms involved, including a healthier metabolic milieu with attenuation of systemic chronic inflammation, as well as adaptations at the vascular (antiatherogenic effects) and heart tissue (myocardial regeneration and cardioprotection) levels. The current evidence for safe implementation of PA and exercise in patients with CVD is also summarized.
Item Type: |
Journal Article (Review Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology 04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Pharmacology |
UniBE Contributor: |
Wilhelm, Matthias |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0195-668X |
Publisher: |
Oxford University Press |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
03 Apr 2023 12:26 |
Last Modified: |
25 Mar 2024 09:55 |
Publisher DOI: |
10.1093/eurheartj/ehad170 |
PubMed ID: |
37005351 |
Uncontrolled Keywords: |
Cardiovascular mortality Exercise and cardiovascular disease Exercise implementation Primary cardiovascular prevention Secondary cardiovascular prevention |
BORIS DOI: |
10.48350/181395 |
URI: |
https://boris.unibe.ch/id/eprint/181395 |