Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study

Rauch, Andri; Kutalik, Zoltán; Descombes, Patrick; Cai, Tao; Di Iulio, Julia; Mueller, Tobias; Bochud, Murielle; Battegay, Manuel; Bernasconi, Enos; Borovicka, Jan; Colombo, Sara; Cerny, Andreas; Dufour, Jean-François; Furrer, Hansjakob; Günthard, Huldrych F; Heim, Markus; Hirschel, Bernard; Malinverni, Raffaele; Moradpour, Darius; Müllhaupt, Beat; ... (2010). Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastroenterology, 138(4), 1338-45, 1345.e1-7. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2009.12.056

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Hepatitis C virus (HCV) induces chronic infection in 50% to 80% of infected persons; approximately 50% of these do not respond to therapy. We performed a genome-wide association study to screen for host genetic determinants of HCV persistence and response to therapy.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology
UniBE Contributor:	Rauch, Andri, Dufour, Jean-François, Furrer, Hansjakob
ISSN:	0016-5085
Publisher:	Elsevier
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:12
Last Modified:	05 Dec 2022 14:02
Publisher DOI:	10.1053/j.gastro.2009.12.056
PubMed ID:	20060832
Web of Science ID:	000276091800023
URI:	https://boris.unibe.ch/id/eprint/2708 (FactScience: 205575)