Glucagon-like peptide-1 receptor imaging for localization of insulinomas

Christ, Emanuel; Wild, Damian; Forrer, Flavio; Brändle, Michael; Sahli, Rahel; Clerici, Thomas; Gloor, Beat; Martius, Ferdinand; Maecke, Helmut; Reubi, Jean-Claude (2009). Glucagon-like peptide-1 receptor imaging for localization of insulinomas. Journal of clinical endocrinology and metabolism, 94(11), pp. 4398-405. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2009-1082

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The surgical removal of insulinomas is hampered by difficulties to localize it using conventional radiological procedures. Recently these tumors were shown to exhibit a very high density of glucagon-like peptide-1 receptors (GLP-1R) in vitro that may be used as specific targets for in vivo receptor radiolabeling.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition

UniBE Contributor:

Christ, Emanuel; Kappeler, Andreas; Sahli, Rahel Gerda and Reubi-Kattenbusch, Jean-Claude

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

0021-972X

ISBN:

19820010

Publisher:

Endocrine Society

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:08

Last Modified:

14 Oct 2019 17:43

Publisher DOI:

10.1210/jc.2009-1082

PubMed ID:

19820010

Web of Science ID:

000271470800035

URI:

https://boris.unibe.ch/id/eprint/29972 (FactScience: 165555)

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