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Antwi, Kwadwo; Hepprich, Matthias; Müller, Natasha A; Reubi, Jean Claude; Fani, Melpomeni; Rottenburger, Christof; Nicolas, Guillaume; Kaul, Felix; Christ, Emanuel R; Wild, Damian (2020). Pitfalls in the Detection of Insulinomas With Glucagon-Like Peptide-1 Receptor Imaging. Clinical nuclear medicine, 45(9), e386-e392. Wolters Kluwer Health 10.1097/RLU.0000000000003124
Reubi, Jean Claude; Fourmy, Daniel; Cordomi, Arnau; Tikhonova, Irina G; Gigoux, Véronique (2020). GIP receptor: Expression in neuroendocrine tumours, internalization, signalling from endosomes and structure-function relationship studies. Peptides, 125, p. 170229. Elsevier 10.1016/j.peptides.2019.170229
Hepprich, Matthias; Antwi, Kwadwo; Waser, Beatrice; Reubi, Jean Claude; Wild, Damian; Christ, Emanuel R. (2020). Brunner's Gland Hyperplasia in a Patient after Roux-Y Gastric Bypass: An Important Pitfall in GLP-1 Receptor Imaging. Case reports in endocrinology, 2020(4510910), p. 4510910. Hindawi 10.1155/2020/4510910
Antwi, Kwadwo; Nicolas, Guillaume; Fani, Melpomeni; Heye, Tobias; Pattou, Francois; Grossman, Ashley; Chanson, Philippe; Reubi, Jean Claude; Perren, Aurel; Gloor, Beat; Vogt, Deborah R; Wild, Damian; Christ, Emanuel (2019). 68Ga-exendin-4 PET/CT detects insulinomas in patients with endogenous hyperinsulinemic hypoglycemia in MEN-1. The journal of clinical endocrinology and metabolism, 104(12), pp. 5843-5852. Oxford University Press 10.1210/jc.2018-02754
Daly, Adrian; Rostomyan, Liliya; Betea, Daniela; Bonneville, Jean Francois; Villa, Chiara; Pellegata, Natalia S; Waser, Beatrice; Reubi-Kattenbusch, Jean-Claude; Waeber Stephan, Catherine; Christ, Emanuel; Beckers, Albert (2019). AIP-mutated acromegaly resistant to first-generation somatostatin analogs: long-term control with pasireotide LAR in two patients. Endocrine Connections, 8(4), pp. 367-377. BioScientifica 10.1530/EC-19-0004
Kaloudi, Aikaterini; Lymperis, Emmanouil; Kanellopoulos, Panagiotis; Waser, Beatrice; de Jong, Marion; Krenning, Eric P; Reubi, Jean Claude; Nock, Berthold A; Maina, Theodosia (2019). Localization of 99mTc-GRP Analogs in GRPR-Expressing Tumors: Effects of Peptide Length and Neprilysin Inhibition on Biological Responses. Pharmaceuticals, 12(1) MDPI 10.3390/ph12010042
Abiraj, Keelara; Ursillo, Samer; Tamma, Maria Luisa; Rylova, Svetlana N; Waser, Beatrice; Constable, Edwin C; Fani, Melpomeni; Nicolas, Guillaume P; Reubi, Jean Claude; Maecke, Helmut R (2018). The tetraamine chelator outperforms HYNIC in a new technetium-99m-labelled somatostatin receptor 2 antagonist. EJNMMI research, 8(1), p. 75. Springer 10.1186/s13550-018-0428-y
Nicolas, Guillaume P; Beykan, Seval; Bouterfa, Hakim; Kaufmann, Jens; Bauman, Andreas; Lassmann, Michael; Reubi, Jean Claude; Rivier, Jean E F; Maecke, Helmut R; Fani, Melpomeni; Wild, Damian (2018). Safety, Biodistribution, and Radiation Dosimetry of Ga-OPS202 in Patients with Gastroenteropancreatic Neuroendocrine Tumors: A Prospective Phase I Imaging Study. Journal of nuclear medicine, 59(6), pp. 909-914. Society of Nuclear Medicine 10.2967/jnumed.117.199737
Nock, Berthold A; Charalambidis, David; Sallegger, Werner; Waser, Beatrice; Mansi, Rosalba; Nicolas, Guillaume P; Ketani, Eleni; Nikolopoulou, Anastasia; Fani, Melpomeni; Reubi, Jean-Claude; Maina, Theodosia (2018). New Gastrin Releasing Peptide Receptor-Directed [Tc]Demobesin 1 Mimics: Synthesis and Comparative Evaluation. Journal of medicinal chemistry, 61(7), pp. 3138-3150. American Chemical Society 10.1021/acs.jmedchem.8b00177
Körner, M.; Waser, Beatrice; Christ, E.; Beck, J.; Reubi, J.C. (2018). A Critical Evaluation of sst3 and sst5 Immunohistochemistry in Human Pituitary Adenomas. Neuroendocrinology, 106(2), pp. 116-127. Karger 10.1159/000472563
Wan, Ming Young Simon; Endozo, Raymond; Michopoulou, Sofia; Shortman, Robert; Rodriguez-Justo, Manuel; Menezes, Leon; Yusuf, Syed; Richards, Toby; Wild, Damian; Waser, Beatrice; Reubi, Jean Claude; Groves, Ashley (2017). PETCT Imaging of Unstable Carotid Plaque with Ga-68 labelled Somatostatin Receptor Ligand. Journal of nuclear medicine, 58(5), pp. 774-780. Society of Nuclear Medicine 10.2967/jnumed.116.181438
Popp, Ilinca; Del Pozzo, Luigi; Waser, Beatrice; Reubi, Jean Claude; Meyer, Philipp T; Maecke, Helmut R; Gourni, Eleni (2017). Approaches to improve metabolic stability of a statine-based GRP receptor antagonist. Nuclear medicine and biology, 45, pp. 22-29. Elsevier 10.1016/j.nucmedbio.2016.11.004
Reubi, Jean Claude; Waser, Beatrice; Maecke, Helmut R; Rivier, Jean E (2016). HIGHLY INCREASED 125I-JR11 ANTAGONIST BINDING IN VITRO REVEALS NOVEL INDICATIONS FOR SST2 TARGETING IN HUMAN CANCERS. Journal of nuclear medicine, 58(2), pp. 300-306. Society of Nuclear Medicine 10.2967/jnumed.116.177733
Rylova, Svetlana N; Waser, Beatrice; Del Pozzo, Luigi; Tönnesmann, Roswitha; Mansi, Rosalba; Meyer, Philipp T; Reubi, Jean Claude; Maecke, Helmut R (2016). Approaches to Improve the Pharmacokinetics of Radiolabeled Glucagon-Like Peptide-1 Receptor Ligands Using Antagonistic Tracers. Journal of nuclear medicine, 57(8), pp. 1282-1288. Society of Nuclear Medicine 10.2967/jnumed.115.168948
Gourni, Eleni; Del Pozzo, Luigi; Kheirallah, Emilie; Smerling, Christiane; Waser, Beatrice; Reubi, Jean-Claude; Paterson, Brett M; Donnelly, Paul S; Meyer, Philipp T; Maecke, Helmut R (2015). Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer. Molecular Pharmaceutics, 12(8), pp. 2781-2790. American Chemical Society 10.1021/mp500671j
Antwi, Kwadwo; Fani, Melpomeni; Nicolas, Guillaume; Rottenburger, Christof; Heye, Tobias; Reubi, Jean Claude; Gloor, Beat; Christ, Emanuel; Wild, Damian (2015). Localization of Hidden Insulinomas with 68Ga-DOTA-Exendin-4 PET/CT: A Pilot Study. Journal of nuclear medicine, 56(7), pp. 1075-1078. Society of Nuclear Medicine 10.2967/jnumed.115.157768
Kolenc Peitl, Petra; Tamma, MariaLuisa; Kroselj, Marko; Braun, Friederike; Waser, Beatrice; Reubi, Jean Claude; Sollner Dolenc, Marija; Maecke, Helmut R; Mansi, Rosalba (2015). Stereochemistry of Amino Acid Spacers Determines the Pharmacokinetics of (111)In-DOTA-Minigastrin Analogues for Targeting the CCK2/Gastrin Receptor. Bioconjugate chemistry, 26(6), pp. 1113-1119. American Chemical Society 10.1021/acs.bioconjchem.5b00187
Christ, Emanuel; Wild, Damian; Antwi, Kwadwo; Waser, Beatrice; Fani, Melpomeni; Schwanda, Stefanie; Heye, Tobias; Schmid, Christoph; Baer, Hans Ulrich; Perren, Aurel; Reubi, Jean Claude (2015). Preoperative localization of adult nesidioblastosis using (68)Ga-DOTA-exendin-4-PET/CT. Endocrine, 50(3), pp. 821-823. Springer 10.1007/s12020-015-0633-7
Reubi, Jean Claude; Waser, Beatrice (2015). Triple-peptide receptor targeting in vitro allows detection of all tested gut and bronchial NETs. Journal of nuclear medicine, 56(4), pp. 613-615. Society of Nuclear Medicine 10.2967/jnumed.114.153189
Mansi, Rosalba; Abiraj, Keelara; Wang, Xuejuan; Tamma, Maria Luisa; Gourni, Eleni; Cescato, Renzo; Berndt, Sandra; Reubi, Jean Claude; Maecke, Helmut R (2015). Evaluation of three different families of bombesin receptor radioantagonists for targeted imaging and therapy of gastrin releasing peptide receptor (GRP-R) positive tumors. Journal of medicinal chemistry, 58(2), pp. 682-691. American Chemical Society 10.1021/jm5012066
Körner Jachertz, Meike; Waser, Beatrice; Strobel, Oliver; Büchler, Markus; Reubi, Jean Claude (2015). Neurotensin receptors in pancreatic ductal carcinomas. EJNMMI research, 5(17), p. 17. Springer 10.1186/s13550-015-0094-2
Körner Jachertz, Meike; Waser, Beatrice; Reubi, Jean Claude (2015). Does somatostatin or gastric inhibitory peptide receptor expression correlate with tumor grade and stage in gut neuroendocrine tumors? Neuroendocrinology, 101(1), pp. 45-57. Karger 10.1159/000371804
Reubi, Jean-Claude (2014). Strict rules are needed for validation of G-protein-coupled receptor immunohistochemical studies in human tissues. Endocrine, 47(3), pp. 659-661. Springer 10.1007/s12020-014-0320-0
Gourni, Eleni; Mansi, Rosalba; Jamous, Mazen; Waser, Beatrice; Smerling, Christiane; Burian, Antje; Buchegger, Franz; Reubi, Jean-Claude; Maecke, Helmut R (2014). N-terminal modifications improve the receptor affinity and pharmacokinetics of radiolabeled peptidic gastrin-releasing peptide receptor antagonists: examples of 68Ga- and 64Cu-labeled peptides for PET imaging. Journal of nuclear medicine, 55(10), pp. 1719-1725. Society of Nuclear Medicine 10.2967/jnumed.114.141242
Waser, Beatrice; Blank, Annika; Karamitopoulou, Evanthia; Perren, Aurel; Reubi, Jean-Claude (2014). Glucagon-like-peptide-1 receptor expression in normal and diseased human thyroid and pancreas. Modern pathology, 28(3), pp. 391-402. Nature Publishing Group 10.1038/modpathol.2014.113
Maina, Theodosia; Cescato, Renzo; Waser, Beatrice; Tatsi, Aikaterini; Kaloudi, Aikaterini; Krenning, Eric P; de Jong, Marion; Nock, Berthold A; Reubi, Jean-Claude (2014). [111In-DOTA]LTT-SS28, a first pansomatostatin radioligand for in vivo targeting of somatostatin receptor-positive tumors. Journal of medicinal chemistry, 57(15), pp. 6564-6571. American Chemical Society 10.1021/jm500581d
Jamous, Mazen; Tamma, Maria L; Gourni, Eleni; Waser, Beatrice; Reubi, Jean-Claude; Maecke, Helmut R; Mansi, Rosalba (2014). PEG spacers of different length influence the biological profile of bombesin-based radiolabeled antagonists. Nuclear medicine and biology, 41(6), pp. 464-470. Elsevier 10.1016/j.nucmedbio.2014.03.014
Wild, Damian; Fani, Melpomeni; Fischer, Richard; Del Pozzo, Luigi; Kaul, Felix; Krebs, Simone; Fischer, Richard; Rivier, Jean E F; Reubi, Jean-Claude; Maecke, Helmut R; Weber, Wolfgang A (2014). Comparison of Somatostatin Receptor Agonist and Antagonist for Peptide Receptor Radionuclide Therapy: A Pilot Study. Journal of nuclear medicine, 55(8), pp. 1248-1252. Society of Nuclear Medicine 10.2967/jnumed.114.138834
Waser, Beatrice; Reubi, Jean-Claude (2014). Radiolabelled GLP-1 receptor antagonist binds to GLP-1 receptor-expressing human tissues. European journal of nuclear medicine and molecular imaging, 41(6), pp. 1166-1171. Springer 10.1007/s00259-013-2684-4
Gourni, Eleni; Waser, Beatrice; Clerc, Pascal; Fourmy, Daniel; Reubi, Jean-Claude; Maecke, Helmut R (2014). The Glucose-Dependent Insulinotropic Polypeptide Receptor: A Novel Target for Neuroendocrine Tumor Imaging-First Preclinical Studies. Journal of nuclear medicine, 55(6), pp. 976-982. Society of Nuclear Medicine 10.2967/jnumed.113.133744
Mikkola, Kirsi; Yim, Cheng-Bin; Fagerholm, Veronica; Ishizu, Tamiko; Elomaa, Viki-Veikko; Rajander, Johan; Jurttila, Jori; Saanijoki, Tiina; Tolvanen, Tuula; Tirri, Marko; Gourni, Eleni; Béhé, Martin; Gotthardt, Martin; Reubi, Jean-Claude; Mäcke, Helmut; Roivainen, Anne; Solin, Olof; Nuutila, Pirjo (2014). Erratum to: (64)Cu- and (68)Ga-Labelled [Nle (14),Lys (40)(Ahx-NODAGA)NH 2]-Exendin-4 for Pancreatic Beta Cell Imaging in Rats. Molecular imaging and biology, 16(2), p. 293. Springer 10.1007/s11307-013-0700-5
Mikkola, Kirsi; Kirsi, Mikkola; Yim, Cheng-Bin; Cheng-Bin, Yim; Fagerholm, Veronica; Veronica, Fagerholm; Ishizu, Tamiko; Tamiko, Ishizu; Elomaa, Viki-Veikko; Viki-Veikko, Elomaa; Rajander, Johan; Johan, Rajander; Jurttila, Jori; Jori, Jurttila; Saanijoki, Tiina; Tiina, Saanijoki; Tolvanen, Tuula; Tuula, Tolvanen; Tirri, Marko; Marko, Tirri; ... (2014). 64Cu- and 68Ga-labelled [Nle(14),Lys(40)(Ahx-NODAGA)NH2]-exendin-4 for pancreatic beta cell imaging in rats. Molecular imaging and biology, 16(2), pp. 255-263. Springer 10.1007/s11307-013-0691-2
Tatsi, Aikaterini; Maina, Theodosia; Cescato, Renzo; Waser, Beatrice; Krenning, Eric P; de Jong, Marion; Cordopatis, Paul; Reubi, Jean-Claude; Nock, Berthold A (2014). [DOTA]Somatostatin-14 analogs and their (111)In-radioligands: effects of decreasing ring-size on sst1-5 profile, stability and tumor targeting. European journal of medicinal chemistry, 73, pp. 30-37. Elsevier Masson SAS 10.1016/j.ejmech.2013.12.003
Körner Jachertz, Meike; Waser, Beatrice; Rehmann, Ruth; Reubi, Jean-Claude (2014). Early over-expression of GRP receptors in prostatic carcinogenesis. Prostate, 74(2), pp. 217-224. Wiley-Blackwell 10.1002/pros.22743
Komor, Jan; Reubi, Jean-Claude; Christ, Emanuel R. (2014). Peptide receptor radionuclide therapy in a patient with disabling non-functioning pituitary adenoma. Pituitary, 17(3), pp. 227-231. Springer Science + Business Media 10.1007/s11102-013-0494-0
Wieser, Gesche; Mansi, Rosalba; Grosu, Anca L; Schultze-Seemann, Wolfgang; Dumont-Walter, Rebecca A; Meyer, Philipp T; Maecke, Helmut R; Reubi, Jean-Claude; Weber, Wolfgang A (2014). Positron emission tomography (PET) imaging of prostate cancer with a gastrin releasing peptide receptor antagonist - from mice to men. Theranostics, 4(4), pp. 412-419. Ivyspring International 10.7150/thno.7324
Wicki, Andreas; Wild, Damian; Prêtre, Vincent; Mansi, Rosalba; Orleth, Annette; Reubi, Jean-Claude; Rochlitz, Christoph; Mamot, Christoph; Mäcke, Helmut R; Christofori, Gerhard (2014). Synergism of peptide receptor-targeted Auger electron radiation therapy with anti-angiogenic compounds in a mouse model of neuroendocrine tumors. EJNMMI research, 4(1), p. 9. Springer 10.1186/2191-219X-4-9
Reubi, Jean-Claude; Schonbrunn, Agnes (2013). Illuminating somatostatin analog action at neuroendocrine tumor receptors. Trends in Pharmacological Sciences, 34(12), pp. 676-688. Elsevier 10.1016/j.tips.2013.10.001
Sparr, Christof; Purkayastha, Nirupam; Yoshinari, Tomohiro; Seebach, Dieter; Maschauer, Simone; Prante, Olaf; Hübner, Harald; Gmeiner, Peter; Kolesinska, Beata; Cescato, Renzo; Waser, Beatrice; Reubi, Jean-Claude (2013). Syntheses, receptor bindings, in vitro and in vivo stabilities and biodistributions of DOTA-neurotensin(8-13) derivatives containing β-amino acid residues - a lesson about the importance of animal experiments. Chemistry & Biodiversity, 10(12), pp. 2101-2121. Verlag Helvetica Chimica Acta 10.1002/cbdv.201300331
Christ, Emanuel; Wild, Damian; Ederer, Susanne; Béhé, Martin; Nicolas, Guillaume; Caplin, Martyn E.; Brändle, Michael; Clerici, Thomas; Fischli, Stefan; Stettler, Christoph; Ell, Peter J.; Seufert, Jochen; Gloor, Beat; Perren, Aurel; Reubi, Jean-Claude; Forrer, Flavio (2013). Glucagon-like peptide-1 receptor imaging for the localisation of insulinomas: a prospective multicentre imaging study. The lancet. Diabetes & endocrinology, 1(2), pp. 115-122. Elsevier 10.1016/S2213-8587(13)70049-4
Dumont, Rebecca A.; Tamma, MariaLuisa; Braun, Friederike; Borkowski, Sandra; Reubi, Jean-Claude; Maecke, Helmut; Weber, Wolfgang A.; Mansi, Rosalba (2013). Targeted radiotherapy of prostate cancer with a gastrin-releasing peptide receptor antagonist is effective as monotherapy and in combination with rapamycin. Journal of nuclear medicine, 54(5), pp. 762-769. Society of Nuclear Medicine 10.2967/jnumed.112.112169
Mansi, Rosalba; Fleischmann, Achim; Mäcke, Helmut R.; Reubi, Jean-Claude (2013). Targeting GRPR in urological cancers--from basic research to clinical application. Nature Reviews. Urology, 10(4), pp. 235-244. Nature Publishing Group 10.1038/nrurol.2013.42
Wild, Damian; Bomanji, Jamshed B.; Benkert, Pascal; Maecke, Helmut; Ell, Peter J.; Reubi, Jean-Claude; Caplin, Martyn E. (2013). Comparison of 68Ga-DOTANOC and 68Ga-DOTATATE PET/CT within patients with gastroenteropancreatic neuroendocrine tumors. Journal of nuclear medicine, 54(3), pp. 364-372. Society of Nuclear Medicine 10.2967/jnumed.112.111724
Körner Jachertz, Meike; Reubi, Jean-Claude (2013). Somatostatin/NPY. In: Kastin, Abba J. (ed.) Handbook of Biologically Active Peptides, 2nd ed. (pp. 548-555). Amsterdam: Elsevier
Waser, Beatrice; Rehmann, Ruth; Sanchez, Claire; Fourmy, Daniel; Reubi, Jean-Claude (2012). Glucose-dependent insulinotropic polypeptide receptors in most gastroenteropancreatic and bronchial neuroendocrine tumors. Journal of clinical endocrinology and metabolism, 97(2), pp. 482-8. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2011-2454
Sanchez, Claire; Escrieut, Chantal; Clerc, Pascal; Gigoux, Véronique; Waser, Beatrice; Reubi, Jean-Claude; Fourmy, Daniel (2012). Characterization of a novel five-transmembrane domain cholecystokinin-2 receptor splice variant identified in human tumors. Molecular and cellular endocrinology, 349(2), pp. 170-9. Shannon: Elsevier Ireland 10.1016/j.mce.2011.10.010
von Guggenberg, Elisabeth; Rangger, Christine; Sosabowski, Jane; Laverman, Peter; Reubi, Jean-Claude; Virgolini, Irene Johanna; Decristoforo, Clemens (2012). Preclinical Evaluation of Radiolabeled DOTA-Derivatized Cyclic Minigastrin Analogs for Targeting Cholecystokinin Receptor Expressing Malignancies. Molecular imaging and biology, 14(3), pp. 366-75. New York, N.Y.: Springer 10.1007/s11307-011-0506-2
Win, Thida; Screaton, Nicholas J; Porter, Joanna; Endozo, Raymondo; Wild, Damian; Kayani, Irfan; Dickson, John; Shortman, Robert I; Reubi, Jean-Claude; Ell, Peter J; Groves, Ashley M (2012). Novel positron emission tomography/computed tomography of diffuse parenchymal lung disease combining a labeled somatostatin receptor analogue and 2-deoxy-2[¹⁸F]fluoro-D-glucose. Molecular imaging, 11(2), pp. 91-8. Hamilton, Ont.: Decker 10.1097/00005382-199621000-00001
Waser, Beatrice; Cescato, Renzo; Liu, Qisheng; Kao, Yachu J; Körner, Meike; Christ, Emanuel; Schonbrunn, Agnes; Reubi, Jean-Claude (2012). Phosphorylation of sst2 receptors in neuroendocrine tumors after octreotide treatment of patients. American journal of pathology, 180(5), pp. 1942-9. New York, N.Y.: Elsevier 10.1016/j.ajpath.2012.01.041
Körner, Meike; Waser, Beatrice; Schonbrunn, Agnes; Perren, Aurel; Reubi, Jean (2012). Somatostatin receptor subtype 2A immunohistochemistry using a new monoclonal antibody selects tumors suitable for in vivo somatostatin receptor targeting. The American journal of surgical pathology, 36(2), pp. 242-52. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/PAS.0b013e31823d07f3
Körner, Meike; Christ, Emanuel; Wild, Damian; Reubi, Jean Claude (2012). Glucagon-like peptide-1 receptor overexpression in cancer and its impact on clinical applications. Frontiers in endocrinology, 3, p. 158. Lausanne: Frontiers Research Foundation 10.3389/fendo.2012.00158
Körner, Meike; Rehmann, Ruth; Reubi, Jean-Claude (2012). GLP-2 receptors in human disease: high expression in gastrointestinal stromal tumors and Crohn's disease. Molecular and cellular endocrinology, 364(1-2), pp. 46-53. Shannon: Elsevier Ireland 10.1016/j.mce.2012.08.008
Zhang, Hanwen; Abiraj, Keelara; Thorek, Daniel L. J.; Waser, Beatrice; Smith-Jones, Peter M.; Honer, Michael; Reubi, Jean-Claude; Maecke, Helmut R. (2012). Evolution of bombesin conjugates for targeted PET imaging of tumors. PLoS ONE, 7(9), e44046. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0044046
Nock, Berthold A; Cescato, Renzo; Ketani, Eleni; Waser, Beatrice; Reubi, Jean-Claude; Maina, Theodosia (2012). [(99m)Tc]Demomedin C, a radioligand based on human gastrin releasing peptide(18-27): synthesis and preclinical evaluation in gastrin releasing peptide receptor-expressing models. Journal of medicinal chemistry, 55(19), pp. 8364-74. Easton, Pa.: American Chemical Society 10.1021/jm300741f
Wang, Xuejuan; Fani, Melpomeni; Schulz, Stefan; Rivier, Jean; Reubi, Jean-Claude; Maecke, Helmut R (2012). Comprehensive evaluation of a somatostatin-based radiolabelled antagonist for diagnostic imaging and radionuclide therapy. European journal of nuclear medicine and molecular imaging, 39(12), pp. 1876-85. Berlin: Springer 10.1007/s00259-012-2231-8
Fani, Melpomeni; Braun, Friederike; Waser, Beatrice; Beetschen, Karin; Cescato, Renzo; Erchegyi, Judit; Rivier, Jean E; Weber, Wolfgang A; Maecke, Helmut R; Reubi, Jean-Claude (2012). Unexpected sensitivity of sst2 antagonists to N-terminal radiometal modifications. Journal of nuclear medicine, 53(9), pp. 1481-9. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.112.102764
Lee, Misu; Waser, Beatrice; Reubi, Jean-Claude; Pellegata, Natalia S (2012). Secretin receptor promotes the proliferation of endocrine tumor cells via the PI3K/AKT pathway. Molecular endocrinology, 26(8), pp. 1394-405. Bethesda, Md.: Endocrine Society 10.1210/me.2012-1055
Tatsi, Aikaterini; Maina, Theodosia; Cescato, Renzo; Waser, Beatrice; Krenning, Eric P; de Jong, Marion; Cordopatis, Paul; Reubi, Jean-Claude; Nock, Berthold A (2012). [111In-DOTA]Somatostatin-14 analogs as potential pansomatostatin-like radiotracers - first results of a preclinical study. EJNMMI research, 2(1), p. 25. Berlin: Springer 10.1186/2191-219X-2-25
Allen, Camryn D; Waser, Beatrice; Körner, Meike; Reubi, Jean-Claude; Lee, Soon; Rivier, Catherine (2011). Neuropeptide Y acts within the rat testis to inhibit testosterone secretion. Neuropeptides, 45(1), pp. 55-61. Amsterdam: Elsevier 10.1016/j.npep.2010.10.006
Mansi, Rosalba; Wang, Xuejuan; Forrer, Flavio; Waser, Beatrice; Cescato, Renzo; Graham, Keith; Borkowski, Sandra; Reubi, Jean-Claude; Maecke, Helmut R (2011). Development of a potent DOTA-conjugated bombesin antagonist for targeting GRPr-positive tumours. European journal of nuclear medicine and molecular imaging, 38(1), pp. 97-107. Berlin: Springer 10.1007/s00259-010-1596-9
Wild, Damian; Christ, Emanuel; Caplin, Martyn E; Kurzawinski, Tom R; Forrer, Flavio; Brändle, Michael; Seufert, Jochen; Weber, Wolfgang A; Bomanji, Jamshed; Perren, Aurel; Ell, Peter J; Reubi, Jean Claude (2011). Glucagon-like peptide-1 versus somatostatin receptor targeting reveals 2 distinct forms of malignant insulinomas. Journal of nuclear medicine, 52(7), pp. 1073-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.110.085142
Reubi, Jean-Claude; Fleischmann, Achim; Waser, Beatrice; Rehmann, Ruth (2011). Concomitant vascular GRP-receptor and VEGF-receptor expression in human tumors: molecular basis for dual targeting of tumoral vasculature. Peptides, 32(7), pp. 1457-62. New York, N.Y.: Elsevier 10.1016/j.peptides.2011.05.007
Körner, Meike; Waser, Beatriche; Thalmann, George N; Reubi, Jean-Claude (2011). High expression of NPY receptors in the human testis. Molecular and cellular endocrinology, 337(1-2), pp. 62-70. Shannon: Elsevier Ireland 10.1016/j.mce.2011.01.021
Chatenet, David; Cescato, Renzo; Waser, Beatrice; Erchegyi, Judit; Rivier, Jean E; Reubi, Jean-Claude (2011). Novel dimeric DOTA-coupled peptidic Y1-receptor antagonists for targeting of neuropeptide Y receptor-expressing cancers. European journal of nuclear medicine and molecular imaging, 1(1), p. 21. Berlin: Springer 10.1186/2191-219X-1-21
Abiraj, Keelara; Mansi, Rosalba; Tamma, Maria-Luisa; Fani, Melpomeni; Forrer, Flavio; Nicolas, Guillaume; Cescato, Renzo; Reubi, Jean-Claude; Maecke, Helmut R (2011). Bombesin antagonist-based radioligands for translational nuclear imaging of gastrin-releasing peptide receptor-positive tumors. Journal of nuclear medicine, 52(12), pp. 1970-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.111.094375
Cescato, Renzo; Waser, Beatrice; Fani, Melpomeni; Reubi, Jean-Claude (2011). Evaluation of 177Lu-DOTA-sst2 antagonist versus 177Lu-DOTA-sst2 agonist binding in human cancers in vitro. Journal of nuclear medicine, 52(12), pp. 1886-90. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.111.095778
Waser, Beatrice; Beetschen, Karin; Pellegata, Natalia S; Reubi, J.C. (2011). Incretin receptors in non-neoplastic and neoplastic thyroid C cells in rodents and humans: relevance for incretin-based diabetes therapy. Neuroendocrinology, 94(4), pp. 291-301. Basel: Karger 10.1159/000330447
Wild, Damian; Fani, Melpomeni; Behe, Martin; Brink, Ingo; Rivier, Jean E F; Reubi, Jean-Claude; Maecke, Helmut R; Weber, Wolfgang A (2011). First clinical evidence that imaging with somatostatin receptor antagonists is feasible. Journal of nuclear medicine, 52(9), pp. 1412-7. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.111.088922
Erchegyi, Judit; Cescato, Renzo; Waser, Beatrice; Rivier, Jean E; Reubi, Jean-Claude (2011). N-imidazolebenzyl-histidine substitution in somatostatin and in its octapeptide analogue modulates receptor selectivity and function. Journal of medicinal chemistry, 54(17), pp. 5981-7. Easton, Pa.: American Chemical Society 10.1021/jm200307v
Fourmy, Daniel; Gigoux, Véronique; Reubi, Jean Claude (2011). Gastrin in gastrointestinal diseases. Gastroenterology, 141(3), 814-818.e1. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2011.07.006
Fani, Melpomeni; Del Pozzo, Luigi; Abiraj, Keelara; Mansi, Rosalba; Tamma, Maria Luisa; Cescato, Renzo; Waser, Beatrice; Weber, Wolfgang A; Reubi, Jean-Claude; Maecke, Helmut R (2011). PET of somatostatin receptor-positive tumors using 64Cu- and 68Ga-somatostatin antagonists: the chelate makes the difference. Journal of nuclear medicine, 52(7), pp. 1110-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.111.087999
Maecke, Helmut R; Reubi, Jean-Claude (2011). Somatostatin receptors as targets for nuclear medicine imaging and radionuclide treatment. Journal of nuclear medicine, 52(6), pp. 841-4. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.110.084236
Seebach, Dieter; Lukaszuk, Aneta; Patora-Komisarska, Krystyna; Podwysocka, Dominika; Gardiner, James; Ebert, Marc-Olivier; Reubi, Jean-Claude; Cescato, Renzo; Waser, Beatrice; Gmeiner, Peter; Hübner, Harald; Rougeot, Catherine (2011). On the terminal homologation of physiologically active peptides as a means of increasing stability in human serum--neurotensin, opiorphin, B27-KK10 epitope, NPY. Chemistry & Biodiversity, 8(5), pp. 711-39. Zürich: Verlag Helvetica Chimica Acta 10.1002/cbdv.201100093
Ocak, Meltem; Helbok, Anna; Rangger, Christine; Peitl, Petra Kolenc; Nock, Berthold A; Morelli, Giancarlo; Eek, Annemarie; Sosabowski, Jane K; Breeman, Wout A P; Reubi, Jean-Claude; Decristoforo, Clemens (2011). Comparison of biological stability and metabolism of CCK2 receptor targeting peptides, a collaborative project under COST BM0607. European journal of nuclear medicine and molecular imaging, 38(8), pp. 1426-35. Berlin: Springer 10.1007/s00259-011-1818-9
Aloj, Luigi; Aurilio, Michela; Rinaldi, Valentina; D'ambrosio, Laura; Tesauro, Diego; Peitl, Petra Kolenc; Maina, Theodosia; Mansi, Rosalba; von Guggenberg, Elisabeth; Joosten, Lieke; Sosabowski, Jane K; Breeman, Wouter A P; De Blois, Erik; Koelewijn, Stuart; Melis, Marleen; Waser, Beatrice; Beetschen, Karin; Reubi, Jean-Claude; de Jong, Marion (2011). Comparison of the binding and internalization properties of 12 DOTA-coupled and ¹¹¹In-labelled CCK2/gastrin receptor binding peptides: a collaborative project under COST Action BM0607. European journal of nuclear medicine and molecular imaging, 38(8), pp. 1417-25. Berlin: Springer 10.1007/s00259-011-1816-y
Laverman, Peter; Joosten, Lieke; Eek, Annemarie; Roosenburg, Susan; Peitl, Petra Kolenc; Maina, Theodosia; Mäcke, Helmut; Aloj, Luigi; von Guggenberg, Elisabeth; Sosabowski, Jane K; de Jong, Marion; Reubi, Jean-Claude; Oyen, Wim J G; Boerman, Otto C (2011). Comparative biodistribution of 12 ¹¹¹In-labelled gastrin/CCK2 receptor-targeting peptides. European journal of nuclear medicine and molecular imaging, 38(8), pp. 1410-6. Berlin: Springer 10.1007/s00259-011-1806-0
Kolenc-Peitl, Petra; Mansi, Rosalba; Tamma, MariaLuisa; Gmeiner-Stopar, Tanja; Sollner-Dolenc, Marija; Waser, Beatrice; Baum, Richard P; Reubi, Jean-Claude; Maecke, Helmut R (2011). Highly improved metabolic stability and pharmacokinetics of indium-111-DOTA-gastrin conjugates for targeting of the gastrin receptor. Journal of medicinal chemistry, 54(8), pp. 2602-9. Easton, Pa.: American Chemical Society 10.1021/jm101279a
Wild, Damian; Frischknecht, Michael; Zhang, Hanwen; Morgenstern, Alfred; Bruchertseifer, Frank; Boisclair, Julie; Provencher-Bolliger, Anne; Reubi, Jean-Claude; Maecke, Helmut R (2011). Alpha- versus beta-particle radiopeptide therapy in a human prostate cancer model (213Bi-DOTA-PESIN and 213Bi-AMBA versus 177Lu-DOTA-PESIN). Cancer research, 71(3), pp. 1009-18. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-10-1186
Waser, Beatrice; Reubi, Jean-Claude (2011). Value of the radiolabelled GLP-1 receptor antagonist exendin(9-39) for targeting of GLP-1 receptor-expressing pancreatic tissues in mice and humans. European journal of nuclear medicine and molecular imaging, 38(6), pp. 1054-8. Berlin: Springer-Verlag 10.1007/s00259-010-1701-0
Wild, D; Reubi, JC (2011). Localisation d'in insulinome bénin par imagerie des récepteurs du glucagon-like peptide-1. Correspondances en MHDN - métabolismes hormones diabètes & nutrition, 8, pp. 296-297. Courbevoie (F): Edimark
Chatterjee, J; Laufer, B; Beck, JG; Helyes, Z; Pinter, E; Szolcsanyi, J; Horvath, A; Mandl, J; Reubi, JC; Keri, G; Kessler, H (2011). N-Methylated sst2 selective somatostatin cyclic peptide analogue as a potent candidate for treating neurogenic inflammation. ACS medicinal chemistry letters, 2(7), pp. 509-514. Washington, D.C.: American Chemical Society 10.1021/ml200032v
Chatenet, D; Cescato, R; Waser, B; Rivier, J; Reubi, JC (2011). Synthesis and characterization of DOTA-coupled dimeric Y1 receptors antagonists for breast cancer targeting. In: Lebl, M (ed.) Proceeding of the 22nd American Peptide Symposium. American Peptide Society
Zueger, Thomas; Buehler, Annette; Stalder, Mario; Walpoth, Nazan; Reubi, Jean-Claude; Stettler, Christoph (2011). A rare localization of a neuroendocrine tumor. Journal of clinical endocrinology and metabolism, 96(6), pp. 1625-6. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2011-0124
Kempná, Petra; Körner, Meike; Waser, Beatrice; Hofer, Gaby; Nuoffer, Jean-Marc; Reubi, J.C.; Flück, Christa E. (2010). Neuropeptide Y modulates steroid production of human adrenal H295R cells through Y1 receptors. Molecular and cellular endocrinology, 314(1), pp. 101-109. Shannon: Elsevier Ireland 10.1016/j.mce.2009.08.010
Körner, Meike; Waser, Beatrice; Reubi, Jean-Claude; Miller, Laurence J. (2010). CCK2 receptor splice variant with intron 4 retention in human gastrointestinal and lung tumours. Journal of Cellular and Molecular Medicine, 14(4), pp. 933-943. Bucharest (Romania): Wiley 10.1111/j.1582-4934.2009.00859.x
Reubi, J.C.; Perren, A; Rehmann, R; Waser, B; Christ, E; Callery, M; Goldfine, A B; Patti, M E (2010). Glucagon-like peptide-1 (GLP-1) receptors are not overexpressed in pancreatic islets from patients with severe hyperinsulinaemic hypoglycaemia following gastric bypass. Diabetologia, 53(12), pp. 2641-5. Heidelberg: Springer-Verlag 10.1007/s00125-010-1901-y
Fani, Melpomeni; Mueller, Andreas; Tamma, Maria-Luisa; Nicolas, Guillaume; Rink, Hans R; Cescato, Renzo; Reubi, Jean-Claude; Maecke, Helmut R (2010). Radiolabeled bicyclic somatostatin-based analogs: a novel class of potential radiotracers for SPECT/PET of neuroendocrine tumors. Journal of nuclear medicine, 51(11), pp. 1771-9. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.110.076695
Waser, Beatrice; Cescato, Renzo; Tamma, Maria-Luisa; Maecke, Helmut R; Reubi, Jean-Claude (2010). Absence of somatostatin SST(2) receptor internalization in vivo after intravenous SOM230 application in the AR42J animal tumor model. European journal of pharmacology, 644(1-3), pp. 257-62. Amsterdam: Elsevier 10.1016/j.ejphar.2010.07.005
Reubi, Jean Claude; Erchegyi, Judit; Cescato, Renzo; Waser, Beatrice; Rivier, Jean E (2010). Switch from antagonist to agonist after addition of a DOTA chelator to a somatostatin analog. European journal of nuclear medicine and molecular imaging, 37(8), pp. 1551-8. Berlin: Springer-Verlag 10.1007/s00259-010-1445-x
Abiraj, Keelara; Mansi, Rosalba; Tamma, Maria-Luisa; Forrer, Flavio; Cescato, Renzo; Reubi, Jean-Claude; Akyel, Kayhan G; Maecke, Helmut R (2010). Tetraamine-derived bifunctional chelators for technetium-99m labelling: synthesis, bioconjugation and evaluation as targeted SPECT imaging probes for GRP-receptor-positive tumours. Chemistry - a European journal, 16(7), pp. 2115-24. Weinheim: Wiley-VCH 10.1002/chem.200902011
Cescato, Renzo; Loesch, Kimberly A; Waser, Beatrice; Mäcke, Helmut R; Rivier, Jean E; Reubi, Jean-Claude; Schonbrunn, Agnes (2010). Agonist-biased signaling at the sst2A receptor: the multi-somatostatin analogs KE108 and SOM230 activate and antagonize distinct signaling pathways. Molecular endocrinology, 24(1), pp. 240-9. Bethesda, Md.: Endocrine Society 10.1210/me.2009-0321
Christ, Emanuel; Wild, Damian; Reubi, Jean-Claude (2010). Glucagonlike peptide-1 receptor: an example of translational research in insulinomas: a review. Endocrinology and metabolism clinics of North America, 39(4), pp. 791-800. Philadelphia, Pa.: Elsevier 10.1016/j.ecl.2010.09.003
Shastry, Manu; Kayani, Irfan; Wild, Damian; Caplin, Martyn; Visvikis, Dimitris; Gacinovic, Svetislav; Reubi, Jean-Claude; Bomanji, Jamshed B (2010). Distribution pattern of 68Ga-DOTATATE in disease-free patients. Nuclear medicine communications, 31(12), pp. 1025-32. London: Lippincott Williams & Wilkins 10.1097/MNM.0b013e32833f635e
Di Cianni, Alessandra; Carotenuto, Alfonso; Brancaccio, Diego; Novellino, Ettore; Reubi, Jean-Claude; Beetschen, Karin; Papini, Anna Maria; Ginanneschi, Mauro (2010). Novel octreotide dicarba-analogues with high affinity and different selectivity for somatostatin receptors. Journal of medicinal chemistry, 53(16), pp. 6188-97. Easton, Pa.: American Chemical Society 10.1021/jm1005868
Laznickova, A; Laznicek, M; Trejtnar, F; Maecke, H R; Eisenwiener, K P; Reubi, J C (2010). Biodistribution of two octreotate analogs radiolabeled with indium and yttrium in rats. Anticancer research, 30(6), pp. 2177-84. Kapandriti: International Inst. of Anticancer Research
Oberg, Kjell E; Reubi, Jean-Claude; Kwekkeboom, Dik J; Krenning, Eric P (2010). Role of somatostatins in gastroenteropancreatic neuroendocrine tumor development and therapy. Gastroenterology, 139(3), 742-53, 753.e1. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2010.07.002
Wild, Damian; Theodoraki, Aikaterini; Kurzawinski, Tom R; Bomanji, Jamshed; Reubi, Jean-Claude; Khan, Rehman; Bouloux, Pierre; Khoo, Bernard (2010). 'Running on empty'. European journal of nuclear medicine and molecular imaging, 37(7), pp. 1439-40. Berlin: Springer 10.1007/s00259-010-1455-8
Cordier, D; Forrer, F; Bruchertseifer, F; Morgenstern, A; Apostolidis, C; Good, S; Müller-Brand, J; Mäcke, H; Reubi, J C; Merlo, A (2010). Targeted alpha-radionuclide therapy of functionally critically located gliomas with 213Bi-DOTA-[Thi8,Met(O2)11]-substance P: a pilot trial. European journal of nuclear medicine and molecular imaging, 37(7), pp. 1335-44. Berlin: Springer 10.1007/s00259-010-1385-5
Wa ngler, Carmen; Waser, Beatrice; Alke, Andrea; Iovkova, Ljuba; Buchholz, Hans-Georg; Niedermoser, Sabrina; Jurkschat, Klaus; Fottner, Christian; Bartenstein, Peter; Schirrmacher, Ralf; Reubi, Jean-Claude; Wester, Hans-Ju rgen; Wa ngler, Bjo rn (2010). One-Step (18)F-Labeling of Carbohydrate-Conjugated Octreotate-Derivatives Containing a Silicon-Fluoride-Acceptor (SiFA): In Vitro and in Vivo Evaluation as Tumor Imaging Agents for Positron Emission Tomography (PET). Bioconjugate chemistry, 21(12), pp. 2289-96. Washington, D.C.: American Chemical Society 10.1021/bc100316c
Reubi, Jean-Claude; Waser, Beatrice; Cescato, Renzo; Gloor, Beat; Stettler, Christoph; Christ, Emanuel (2010). Internalized somatostatin receptor subtype 2 in neuroendocrine tumors of octreotide-treated patients. Journal of clinical endocrinology and metabolism, 95(5), pp. 2343-50. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2009-2487
Christ, Emanuel; Wild, Damian; Forrer, Flavio; Brändle, Michael; Sahli, Rahel; Clerici, Thomas; Gloor, Beat; Martius, Ferdinand; Maecke, Helmut; Reubi, Jean-Claude (2009). Glucagon-like peptide-1 receptor imaging for localization of insulinomas. Journal of clinical endocrinology and metabolism, 94(11), pp. 4398-405. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2009-1082
Mansi, Rosalba; Wang, Xuejuan; Forrer, Flavio; Kneifel, Stefan; Tamma, Maria-Luisa; Waser, Beatrice; Cescato, Renzo; Reubi, Jean-Claude; Maecke, Helmut R (2009). Evaluation of a 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-conjugated bombesin-based radioantagonist for the labeling with single-photon emission computed tomography, positron emission tomography, and therapeutic radionuclides. Clinical cancer research, 15(16), pp. 5240-9. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-08-3145
Fleischmann, Achim; Waser, Beatrice; Reubi, Jean-Claude (2009). High expression of gastrin-releasing peptide receptors in the vascular bed of urinary tract cancers: promising candidates for vascular targeting applications. Endocrine-related cancer, 16(2), pp. 623-33. Bristol: BioScientifica Ltd. 10.1677/ERC-08-0316
Waser, Bea; Tamma, Maria-Luisa; Cescato, Renzo; Maecke, Helmut R; Reubi, Jean-Claude (2009). Highly efficient in vivo agonist-induced internalization of sst2 receptors in somatostatin target tissues. Journal of nuclear medicine, 50(6), pp. 936-41. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.108.061457
Beierle, John M; Horne, W Seth; van Maarseveen, Jan H; Waser, Beatrice; Reubi, Jean-Claude; Ghadiri, M Reza (2009). Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: receptor-selective somatostatin analogues. Angewandte Chemie (International ed.), 48(26), pp. 4725-9. Weinheim: Wiley-VCH 10.1002/anie.200805901
Erchegyi, Judit; Cescato, Renzo; Grace, Christy Rani R; Waser, Beatrice; Piccand, Véronique; Hoyer, Daniel; Riek, Roland; Rivier, Jean E; Reubi, Jean-Claude (2009). Novel, potent, and radio-iodinatable somatostatin receptor 1 (sst1) selective analogues. Journal of medicinal chemistry, 52(9), pp. 2733-46. Easton, Pa.: American Chemical Society 10.1021/jm801314f
Akgün, Eyup; Körner Jachertz, Meike; Gao, Fan; Harikumar, Kaleeckal G; Waser, Beatrice; Reubi, Jean-Claude; Portoghese, Philip S; Miller, Laurence J (2009). Synthesis and in vitro characterization of radioiodinatable benzodiazepines selective for type 1 and type 2 cholecystokinin receptors. Journal of medicinal chemistry, 52(7), pp. 2138-47. Easton, Pa.: American Chemical Society 10.1021/jm801439x
Feytens, Debby; De Vlaeminck, Magali; Cescato, Renzo; Tourwé, Dirk; Reubi, Jean-Claude (2009). Highly potent 4-amino-indolo[2,3-c]azepin-3-one-containing somatostatin mimetics with a range of sst receptor selectivities. Journal of medicinal chemistry, 52(1), pp. 95-104. Easton, Pa.: American Chemical Society 10.1021/jm801205x
Reubi, Jean-Claude; Maecke, Helmut R (2008). Peptide-based probes for cancer imaging. Journal of nuclear medicine, 49(11), pp. 1735-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.108.053041
Wild, Damian; Mäcke, Helmut; Christ, Emanuel; Gloor, Beat; Reubi, Jean-Claude (2008). Glucagon-like peptide 1-receptor scans to localize occult insulinomas. New England journal of medicine NEJM, 359(7), pp. 766-8. Waltham, Mass.: Massachusetts Medical Society MMS 10.1056/NEJMc0802045
Körner, Meike; Waser, Beatrice; Reubi, Jean-Claude (2008). High expression of neuropeptide Y1 receptors in ewing sarcoma tumors. Clinical cancer research, 14(16), pp. 5043-9. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-07-4551
Grace, Christy Rani R; Erchegyi, Judit; Reubi, Jean Claude; Rivier, Jean E; Riek, Roland (2008). Three-dimensional consensus structure of sst2-selective somatostatin (SRIF) antagonists by NMR. Biopolymers, 89(12), pp. 1077-87. Hoboken, N.J.: John Wiley & Sons, Inc. 10.1002/bip.21060
Körner, Meike; Reubi, Jean Claude (2008). Neuropeptide Y receptors in primary human brain tumors: overexpression in high-grade tumors. Journal of neuropathology and experimental neurology, 67(8), pp. 741-9. Hagerstown, Md.: Lippincott Williams & Wilkins
Palii, Stela S; Afzal, Aqeela; Shaw, Lynn C; Pan, Hao; Caballero, Sergio; Miller, Rehae C; Jurczyk, Simona; Reubi, Jean-Claude; Tan, Yufei; Hochhaus, Guenther; Edelhauser, Henry; Geroski, Dayle; Shapiro, Gideon; Grant, Maria B (2008). Nonpeptide somatostatin receptor agonists specifically target ocular neovascularization via the somatostatin type 2 receptor. Investigative ophthalmology & visual science, 49(11), pp. 5094-102. Hagerstown, Md.: Association for Research in Vision and Ophthalmology 10.1167/iovs.08-2289
Good, Stephan; Walter, Martin A; Waser, Beatrice; Wang, Xuejuan; Müller-Brand, Jan; Béhé, Martin P; Reubi, Jean-Claude; Maecke, Helmut R (2008). Macrocyclic chelator-coupled gastrin-based radiopharmaceuticals for targeting of gastrin receptor-expressing tumours. European journal of nuclear medicine and molecular imaging, 35(10), pp. 1868-77. Berlin: Springer 10.1007/s00259-008-0803-4
Erchegyi, Judit; Grace, Christy Rani R; Samant, Manoj; Cescato, Renzo; Piccand, Veronique; Riek, Roland; Reubi, Jean Claude; Rivier, Jean E (2008). Ring size of somatostatin analogues (ODT-8) modulates receptor selectivity and binding affinity. Journal of medicinal chemistry, 51(9), pp. 2668-75. Easton, Pa.: American Chemical Society 10.1021/jm701444y
Grace, Christy Rani R; Erchegyi, Judit; Samant, Manoj; Cescato, Renzo; Piccand, Veronique; Riek, Roland; Reubi, Jean Claude; Rivier, Jean E (2008). Ring size in octreotide amide modulates differently agonist versus antagonist binding affinity and selectivity. Journal of medicinal chemistry, 51(9), pp. 2676-81. Easton, Pa.: American Chemical Society 10.1021/jm701445q
Ginj, Mihaela; Zhang, Hanwen; Eisenwiener, Klaus-Peter; Wild, Damian; Schulz, Stefan; Rink, Hans; Cescato, Renzo; Reubi, Jean Claude; Maecke, Helmut R (2008). New pansomatostatin ligands and their chelated versions: affinity profile, agonist activity, internalization, and tumor targeting. Clinical cancer research, 14(7), pp. 2019-27. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-07-1687
Heppeler, Axel; André, João P; Buschmann, Ingeborg; Wang, Xuejuan; Reubi, Jean-Claude; Hennig, Michael; Kaden, Thomas A; Maecke, Helmut R (2008). Metal-ion-dependent biological properties of a chelator-derived somatostatin analogue for tumour targeting. Chemistry - a European journal, 14(10), pp. 3026-34. Weinheim: Wiley-VCH 10.1002/chem.200701264
Körner, Meike U; Hayes, Gregory M; Carrigan, Patricia E; Rehmann, Ruth; Miller, Laurence J; Reubi, Jean C (2008). Wild-type and splice-variant secretin receptors in lung cancer: overexpression in carcinoid tumors and peritumoral lung tissue. Modern pathology, 21(4), pp. 387-95. London: Nature Publishing Group 10.1038/modpathol.3801005
D'Addona, Debora; Carotenuto, Alfonso; Novellino, Ettore; Piccand, Véronique; Reubi, Jean Claude; Di Cianni, Alessandra; Gori, Francesca; Papini, Anna Maria; Ginanneschi, Mauro (2008). Novel sst5-selective somatostatin dicarba-analogues: synthesis and conformation-affinity relationships. Journal of medicinal chemistry, 51(3), pp. 512-20. Easton, Pa.: American Chemical Society 10.1021/jm070886i
Cescato, Renzo; Maina, Theodosia; Nock, Berthold; Nikolopoulou, Anastasia; Charalambidis, David; Piccand, Véronique; Reubi, Jean Claude (2008). Bombesin receptor antagonists may be preferable to agonists for tumor targeting. Journal of nuclear medicine, 49(2), pp. 318-26. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.107.045054
Gugger, Mathias; White, Richard; Song, Susan; Waser, Bea; Cescato, Renzo; Rivière, Pierre; Reubi, Jean Claude (2008). GPR87 is an overexpressed G-protein coupled receptor in squamous cell carcinoma of the lung. Disease markers, 24(1), pp. 41-50. Amsterdam: IOS Press 10.1155/2008/857474
Betzel, Thomas; Hess, Tobias; Waser, Beatrice; Reubi, Jean-C.; Roesch, Frank (2008). closo-borane conjugated regulatory peptides retain high biological affinity: synthesis of closo-borane conjugated Tyr(3)-octreotate derivatives for BNCT. Bioconjugate chemistry, 19(9), pp. 1796-802. Washington, D.C.: American Chemical Society 10.1021/bc800101h
Cescato, Renzo; Erchegyi, Judith; Waser, Beatrice; Piccand, Véronique; Maecke, Helmut R; Rivier, Jean E; Reubi, Jean Claude (2008). Design and in vitro characterization of highly sst2-selective somatostatin antagonists suitable for radiotargeting. Journal of medicinal chemistry, 51(13), pp. 4030-7. Easton, Pa.: American Chemical Society 10.1021/jm701618q
Nikolopoulou, A; Nock, B; Petrou, C; Cordopatis, P; Reubi, JC; Maina, T (2008). Toward 99mTc-based somatostatins with high affinity for all five somatostatin receptor subtypes. In: Cordopatis PA, Manessi-Zoupa E (ed.) 5th Hellenic Forum on Bioactive Peptides (pp. 195-202). Typorama
Wild, D; Christ, E; Gloor, B; Mäcke, H; Reubi, JC (2008). Nuklearmedizin: Neue nuklearmedizinische Bildgebung zur Lokalisation von okkulten Insulinomen. Schweizerisches Medizin-Forum SMF / Swiss medical forum / Forum médical suisse FMS, 8(51-52), pp. 1009-1010. Basel: EMH Editores Medicorum Helveticorum
Waser, Beatrice; Eltschinger, Véronique; Linder, Karen; Nunn, Adrian; Reubi, Jean Claude (2007). Selective in vitro targeting of GRP and NMB receptors in human tumours with the new bombesin tracer 177Lu-AMBA. European journal of nuclear medicine and molecular imaging, 34(1), pp. 95-100. Berlin: Springer-Verlag 10.1007/s00259-006-0229-9
Fleischmann, Achim; Waser, Beatrice; Reubi, Jean Claude (2007). Overexpression of gastrin-releasing peptide receptors in tumor-associated blood vessels of human ovarian neoplasms. Cellular oncology, 29(5), pp. 421-33. Amsterdam: IOS Press
Reubi, Jean Claude (2007). Peptide receptor expression in GEP-NET. Virchows Archiv, 451 Suppl 1, S47-50. Berlin: Springer-Verlag 10.1007/s00428-007-0443-2
Hayes, Gregory M; Carrigan, Patricia E; Dong, Maoqing; Reubi, Jean Claude; Miller, Laurence J (2007). A novel secretin receptor splice variant potentially useful for early diagnosis of pancreatic carcinoma. Gastroenterology, 133(3), pp. 853-61. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2007.06.013
Wicki, Andreas; Wild, Damian; Storch, Daniel; Seemayer, Christian; Gotthardt, Martin; Behe, Martin; Kneifel, Stefan; Mihatsch, Michael J; Reubi, Jean-Claude; Mäcke, Helmut R; Christofori, Gerhard (2007). [Lys40(Ahx-DTPA-111In)NH2]-Exendin-4 is a highly efficient radiotherapeutic for glucagon-like peptide-1 receptor-targeted therapy for insulinoma. Clinical cancer research, 13(12), pp. 3696-705. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-06-2965
Feytens, Debby; Cescato, Renzo; Reubi, Jean Claude; Tourwé, Dirk (2007). New sst4/5-selective somatostatin peptidomimetics based on a constrained tryptophan scaffold. Journal of medicinal chemistry, 50(14), pp. 3397-401. Easton, Pa.: American Chemical Society 10.1021/jm070246f
Körner, Meike; Stöckli, Martin; Waser, Beatrice; Reubi, Jean Claude (2007). GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting. Journal of nuclear medicine, 48(5), pp. 736-43. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.106.038679
de Visser, M; Bernard, H F; Erion, J L; Schmidt, M A; Srinivasan, A; Waser, B; Reubi, J. C.; Krenning, E P; de Jong, M (2007). Novel 111In-labelled bombesin analogues for molecular imaging of prostate tumours. European journal of nuclear medicine and molecular imaging, 34(8), pp. 1228-38. Berlin: Springer 10.1007/s00259-006-0356-3
Zhang, Hanwen; Schuhmacher, Jochen; Waser, Beatrice; Wild, Damian; Eisenhut, Michael; Reubi, Jean Claude; Maecke, Helmut R (2007). DOTA-PESIN, a DOTA-conjugated bombesin derivative designed for the imaging and targeted radionuclide treatment of bombesin receptor-positive tumours. European journal of nuclear medicine and molecular imaging, 34(8), pp. 1198-208. Berlin: Springer 10.1007/s00259-006-0347-4
Antunes, Patricia; Ginj, Mihaela; Walter, Martin A; Chen, Jianhua; Reubi, Jean-Claude; Maecke, Helmut R (2007). Influence of different spacers on the biological profile of a DOTA-somatostatin analogue. Bioconjugate chemistry, 18(1), pp. 84-92. Washington, D.C.: American Chemical Society 10.1021/bc0601673
Antunes, P; Ginj, M; Zhang, H; Waser, B; Baum, R P; Reubi, J. C.; Maecke, H (2007). Are radiogallium-labelled DOTA-conjugated somatostatin analogues superior to those labelled with other radiometals? European journal of nuclear medicine and molecular imaging, 34(7), pp. 982-93. Berlin: Springer 10.1007/s00259-006-0317-x
Körner, Meike; Reubi, Jean Claude (2007). NPY receptors in human cancer: a review of current knowledge. Peptides, 28(2), pp. 419-25. New York, N.Y.: Elsevier 10.1016/j.peptides.2006.08.037
Melis, M; Forrer, F; Capello, A; Bijster, M; Bernard, B F; Reubi, J C; Krenning, E P; De Jong, M (2007). Up-regulation of somatostatin receptor density on rat CA20948 tumors escaped from low dose [(177)Lu-DOTA(0),Tyr(3)]octreotate therapy. Quarterly journal of nuclear medicine and molecular imaging, 51(4), pp. 324-33. Torino: Minerva Medica
Reubi, Jean Claude (2007). Targeting CCK receptors in human cancers. Current topics in medicinal chemistry, 7(12), pp. 1239-42. Hilversum: Bentham Science Publishers
Fainstein Day, Patricia; Frohman, Lawrence; Garcia Rivello, Hernan; Reubi, Jean Claude; Sevlever, Gustavo; Glerean, Mariela; Fernandez Gianotti, Tomas; Pietrani, Marcelo; Rabadan, Alejandra; Racioppi, Silvina; Bidlingmaier, Martin (2007). Ectopic growth hormone-releasing hormone secretion by a metastatic bronchial carcinoid tumor: a case with a non hypophysial intracranial tumor that shrank during long acting octreotide treatment. Pituitary, 10(3), pp. 311-9. Norwell, Mass.: Springer Science + Business Media 10.1007/s11102-007-0019-9
Storch, D; Schmitt, JS; Waldherr, C; Waser, B; Reubi, Jean-Claude; Maecke, HR (2007). Preclinical evaluation of somatostatin analogs bearing two macrocyclic chelators for high specific activity labeling with radiometals. Radiochimica acta, 95(6), pp. 359-69. München: Oldenbourg 10.1524/ract.2007.95.6.359
Körner, Meike; Hayes, Gregory M; Rehmann, Ruth; Zimmermann, Arthur; Scholz, Arne; Wiedenmann, Bertram; Miller, Laurence J; Reubi, Jean Claude (2006). Secretin receptors in the human liver: expression in biliary tract and cholangiocarcinoma, but not in hepatocytes or hepatocellular carcinoma. Journal of hepatology, 45(6), pp. 825-35. Amsterdam: Elsevier 10.1016/j.jhep.2006.06.016
Waser, Beatrice; Rehmann, Ruth; Rivier, Jean; Vale, Wylie; Reubi, Jean Claude (2006). CRF receptors in the rodent and human cardiovascular systems: Species differences. Peptides, 27(12), pp. 3029-38. New York, N.Y.: Elsevier 10.1016/j.peptides.2006.07.005
Cescato, Renzo; Schulz, Stefan; Waser, Beatrice; Eltschinger, Véronique; Rivier, Jean E; Wester, Hans-Jürgen; Culler, Michael; Ginj, Mihaela; Liu, Qisheng; Schonbrunn, Agnes; Reubi, Jean Claude (2006). Internalization of sst2, sst3, and sst5 receptors: effects of somatostatin agonists and antagonists. Journal of nuclear medicine, 47(3), pp. 502-11. New York, N.Y.: Society of Nuclear Medicine
Schmassmann, Adrian; Zoidl, Georg; Peskar, Brigitta M; Waser, Bea; Schmassmann-Suhijar, Diana; Gebbers, Jan-Olaf; Reubi, Jean Claude (2006). Role of the different isoforms of cyclooxygenase and nitric oxide synthase during gastric ulcer healing in cyclooxygenase-1 and -2 knockout mice. American journal of physiology - gastrointestinal and liver physiology, 290(4), G747-56. Bethesda, Md.: American Physiological Society 10.1152/ajpgi.00416.2005
Wild, Damian; Béhé, Martin; Wicki, Andreas; Storch, Daniel; Waser, Beatrice; Gotthardt, Martin; Keil, Boris; Christofori, Gerhard; Reubi, Jean Claude; Mäcke, Helmut R (2006). [Lys40(Ahx-DTPA-111In)NH2]exendin-4, a very promising ligand for glucagon-like peptide-1 (GLP-1) receptor targeting. Journal of nuclear medicine, 47(12), pp. 2025-33. New York, N.Y.: Society of Nuclear Medicine
Ginj, Mihaela; Zhang, Hanwen; Waser, Beatrice; Cescato, Renzo; Wild, Damian; Wang, Xuejuan; Erchegyi, Judit; Rivier, Jean; Mäcke, Helmut R; Reubi, Jean Claude (2006). Radiolabeled somatostatin receptor antagonists are preferable to agonists for in vivo peptide receptor targeting of tumors. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 103(44), pp. 16436-41. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.0607761103
Ginj, Mihaela; Schmitt, Jörg S; Chen, Jianhua; Waser, Beatrice; Reubi, Jean-Claude; de Jong, Marion; Schulz, Stefan; Maecke, Helmut R (2006). Design, synthesis, and biological evaluation of somatostatin-based radiopeptides. Chemistry & biology, 13(10), pp. 1081-90. San Francisco, Calif.: Current Biology Ltd. 10.1016/j.chembiol.2006.08.012
Lebtahi, Rachida; Moreau, Severine; Marchand-Adam, Sylvain; Debray, Marie-Pierre; Brauner, Michel; Soler, Paul; Marchal, Joëlle; Raguin, Olivier; Gruaz-Guyon, Anne; Reubi, Jean-Claude; Le Guludec, Dominique; Crestani, Bruno (2006). Increased uptake of 111In-octreotide in idiopathic pulmonary fibrosis. Journal of nuclear medicine, 47(8), pp. 1281-7. New York, N.Y.: Society of Nuclear Medicine
Nock, Berthold A; Nikolopoulou, Anastasia; Reubi, Jean-Claude; Maes, Veronique; Conrath, Peter; Tourwé, Dirk; Maina, Theodosia (2006). Toward stable N4-modified neurotensins for NTS1-receptor-targeted tumor imaging with 99mTc. Journal of medicinal chemistry, 49(15), pp. 4767-76. Easton, Pa.: American Chemical Society 10.1021/jm060415g
Grace, Christy Rani R; Erchegyi, Judit; Koerber, Steven C; Reubi, Jean Claude; Rivier, Jean; Riek, Roland (2006). Novel sst2-selective somatostatin agonists. Three-dimensional consensus structure by NMR. Journal of medicinal chemistry, 49(15), pp. 4487-96. Easton, Pa.: American Chemical Society 10.1021/jm060363v
Lantry, Laura E; Cappelletti, Enrico; Maddalena, Mary Ellen; Fox, Jaclyn S; Feng, Weiwei; Chen, Jianqing; Thomas, Regi; Eaton, Stephen M; Bogdan, Nancy J; Arunachalam, Thangavel; Reubi, Jean Claude; Raju, Natarajan; Metcalfe, Edmund C; Lattuada, Luciano; Linder, Karen E; Swenson, Rolf E; Tweedle, Michael F; Nunn, Adrian D (2006). 177Lu-AMBA: Synthesis and characterization of a selective 177Lu-labeled GRP-R agonist for systemic radiotherapy of prostate cancer. Journal of nuclear medicine, 47(7), pp. 1144-52. New York, N.Y.: Society of Nuclear Medicine
Kneifel, Stefan; Cordier, Dominik; Good, Stephan; Ionescu, Mihai C S; Ghaffari, Anthony; Hofer, Silvia; Kretzschmar, Martin; Tolnay, Markus; Apostolidis, Christos; Waser, Beatrice; Arnold, Marlene; Mueller-Brand, Jan; Maecke, Helmut R; Reubi, Jean Claude; Merlo, Adrian (2006). Local targeting of malignant gliomas by the diffusible peptidic vector 1,4,7,10-tetraazacyclododecane-1-glutaric acid-4,7,10-triacetic acid-substance p. Clinical cancer research, 12(12), pp. 3843-50. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-05-2820
Ji, G C; Zhou, S T; Shapiro, G; Reubi, J.C.; Jurczyk, Simona; Carlton, S M (2006). Analgesic activity of a non-peptide imidazolidinedione somatostatin agonist: in vitro and in vivo studies in rat. Pain, 124(1-2), pp. 34-49. Amsterdam: Elsevier 10.1016/j.pain.2006.03.014
Maina, Theodosia; Nock, Berthold A; Cordopatis, Paul; Bernard, Bert F; Breeman, Wout A P; van Gameren, Arthur; van den Berg, Ria; Reubi, Jean-Claude; Krenning, Eric P; de Jong, Marion (2006). [(99m)Tc]Demotate 2 in the detection of sst(2)-positive tumours: a preclinical comparison with [(111)In]DOTA-tate. European journal of nuclear medicine and molecular imaging, 33(7), pp. 831-40. Berlin: Springer 10.1007/s00259-006-0068-8
Gairí, Margarida; Saiz, Pilar; Madurga, Sergio; Roig, Xavier; Erchegyi, Judit; Koerber, Steven C; Reubi, Jean Claude; Rivier, Jean E; Giralt, Ernest (2006). Conformational analysis of a potent SSTR3-selective somatostatin analogue by NMR in water solution. Journal of Peptide Science, 12(2), pp. 82-91. Chichester: John Wiley & Sons 10.1002/psc.743
Reubi, JC (2006). Radiopeptide targeting for tumor therapy: peptide receptor distribution. In: , (ed.) Radionuclide peptide cancer therapy Chinol M (pp. 31-39). London: Taylor & Francis
Rivier, J; Gulyas, J; Erchegyi, J; Koerber, SC; Grace, C; Riek, R; DiGruccio, M; Perrin, M; Rivier, C; Eltschinger, V; Waser, B; Cescato, R; Reubi, J.C.; Vale, W (2006). Guiding principles applied in the design of GPCR-selective hypothalamic hormone agonists and antagonists. In: Insights into Receptor Function and New Drug Development Targets (pp. 117-138). Heidelberg: Springer Verlag 10.1007/3-540-34447-0_8
Gugger, M; Reubi, JC (2006). Somatostatin. In: Kastin, AJ (ed.) (pp. 1123-1130). Amsterdam: Elsevier
Koerner, M; Reubi, JC (2006). Somatostatin and NPY. In: Kastin, AJ (ed.) (pp. 435-444). Amsterdam: Elsevier
Reubi, Jean-Claude; Körner Jachertz, Meike; Waser, Beatrice; Mazzucchelli, Luca; Guillou, Louis (2004). High expression of peptide receptors as a novel target in gastrointestinal stromal tumours. European journal of nuclear medicine and molecular imaging, 31(6), pp. 803-810. Springer-Verlag 10.1007/s00259-004-1476-2
Reubi, Jean-Claude; Gugger, Mathias; Waser, Beatrice (2002). Co-expressed peptide receptors in breast cancer as a molecular basis for in vivo multireceptor tumour targeting. European journal of nuclear medicine and molecular imaging, 29(7), pp. 855-862. Springer-Verlag 10.1007/s00259-002-0794-5
Reubi, Jean-Claude (1997). Relevance of somatostatin receptors and other peptide receptors in pathology. Endocrine pathology, 8(1), pp. 11-20. Springer 10.1007/BF02739703
Laissue, J A; Chappuis, B B; Müller, C; Reubi, J C; Gebbers, J-O (1993). The intestinal immune system and its relation to disease. Digestive diseases, 11(4-5), pp. 298-312. Karger 10.1159/000171421
Anderson, B; Reubi, Jean-Claude; Waser, Beatrice (1979). Labor contracts and negotiations. NLN publications(52-1805), pp. 69-74.
